Members Of Certain Families Research Articles

‘Je suis corse, un homme de village’: Towards a Study of Contemporary Corsican Nationalism (1959–98)

AbstractThis article reconstructs the genesis and developments of contemporary Corsican nationalism between 1959 to 1998, from the emergence of regionalism to the most dramatic phase of the resurgence of violence represented by the murder of Prefect Claude Érignac. The underlying hypothesis for this study is that Corsica embodies the community of destiny through a dialogue between tradition and modernity. With regard to permanency, what remains is a community and clan‐oriented mentality with a lasting impact upon nationalism. The emergence of contemporary Corsican nationalism must be viewed from a dual perspective: on the one hand, as a traditional system reserved for members of certain families according to a clan‐based approach; on the other, there is a protest movement that does not imply the dismantlement of the clan system but its renewal on the basis of criteria of democracy, equality and justice.

Inverse ambiguous functions on some finite non-abelian groups

In Schmitz (Aequ Math 91:373–389, 2017), the first author defines an “inverse ambiguous function” on a group G to be a bijective function $$f:G \rightarrow G$$ satisfying the functional equation $$f^{-1}(x) = (f(x))^{-1}$$ for all $$x \in G$$ . Using a simple criterion involving the number of elements in G not equal to their own inverse, the classification of finite abelian groups admitting inverse ambiguous functions is achieved. In this paper we aim to extend the results from (2017) to determine the existence of inverse ambiguous functions on members of certain families of non-abelian groups, namely the symmetric groups $$S_n$$ , the alternating groups $$A_n$$ , and the general linear groups GL(2, q) over a finite field $$\mathbb {F}_q$$ .

Some Elementary Aspects of Means

We raise several elementary questions pertaining to various aspects of means. These questions refer to both known and newly introduced families of means, and include questions of characterizations of certain families, relations among certain families, comparability among the members of certain families, and concordance of certain sequences of means. They also include questions about internality tests for certain mean-looking functions and about certain triangle centers viewed as means of the vertices. The questions are accessible to people with no background in means, and it is also expected that these people can seriously investigate, and contribute to the solutions of, these problems. The solutions are expected to require no more than simple tools from analysis, algebra, functional equations, and geometry.

Detection of polyoma and corona viruses in bats of Canada

Several instances of emerging diseases in humans appear to be caused by the spillover of viruses endemic to bats, either directly or through other animal intermediaries. The objective of this study was to detect, identify and characterize viruses in bats in the province of Manitoba and other regions of Canada. Bats were sampled from three sources: live-trapped Myotis lucifugus from Manitoba, rabies-negative Eptesicus fuscus, M. lucifugus, M. yumanensis, M. septentrionalis, M. californicus, M. evotis, Lasionycteris (L.) noctivagans and Lasiurus (Las.) cinereus, provided by the Centre of Expertise for Rabies of the Canadian Food Inspection Agency (CFIA), and L. noctivagans, Las. cinereus and Las. borealis collected from a wind farm in Manitoba. We attempted to isolate viruses from fresh tissue samples taken from trapped bats in cultured cells of bat, primate, rodent, porcine, ovine and avian origin. We also screened bat tissues by PCR using primers designed to amplify nucleic acids from members of certain families of viruses. We detected RNA of a group 1 coronavirus from M. lucifugus (3 of 31 animals) and DNA from an as-yet undescribed polyomavirus from female M. lucifugus (4 of 31 animals) and M. californicus (pooled tissues from two females).

Molecular and functional characterization of Arabidopsis Cullin 3A

Cullin proteins, which belong to multigenic families in all eukaryotes, associate with other proteins to form ubiquitin protein ligases (E3s) that target substrates for proteolysis by the 26S proteasome. Here, we present the molecular and genetic characterization of a plant Cullin3. In contrast to fungi and animals, the genome of the model plant Arabidopsis thaliana contains two related CUL3 genes, called CUL3A and CUL3B. We found that CUL3A is ubiquitously expressed in plants and is able to interact with the ring-finger protein RBX1. A genomic search revealed the existence of at least 76 BTB-domain proteins in Arabidopsis belonging to 11 major families. Yeast two-hybrid experiments indicate that representative members of certain families are able to physically interact with both CUL3A and CUL3B, suggesting that Arabidopsis CUL3 forms E3 protein complexes with certain BTB domain proteins. In order to determine the function of CUL3A, we used a reverse genetic approach. The cul3a null mutant flowers slightly later than the control plants. Furthermore, this mutant exhibits a reduced sensitivity of the inhibition of hypocotyl growth in far-red light and miss-expresses COP1. The viability of the mutant plants suggests functional redundancy between the two CUL3 genes in Arabidopsis.

Rational Curves in Calabi-Yau Threefolds#

We study the set of rational curves of a certain topological type in general members of certain families of Calabi-Yau threefolds. For some families we investigate to what extent it is possible to conclude that this set is finite. For other families we investigate whether this set contains at least one point representing an isolated rational curve. Our study is inspired by Johnsen and Kleiman (Johnsen, T., Kleiman, S. (1996). Rational Curves of degree at most 9 on a general quintic threefold. Comm. Algebra 24(8): 2721–2753). Dedicated to Steven L. Kleiman on the occasion of his 60th birthday.

Thematic stratiotai in Byzantine society: A contribution to a new assessment of the subject

Thematic stratiotai in Byzantine society: A contribution to a new assessment of the subject

The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.

Dominant mutations of the SOD1 gene encoding Cu,Zn superoxide dismutase have been found in members of certain families with familial amyotrophic lateral sclerosis (ALS). To better understand the contribution of SOD1 mutations in the pathogenesis of familial ALS, we developed transgenic mice expressing one of the mutations found in familial ALS. These animals display clinical and pathological features closely resembling human ALS. Early changes observed in these animals were intra-axonal and dendritic vacuoles due to dilatation of the endoplasmic reticulum and vacuolar degeneration of mitochondria. We have reported that the Golgi apparatus of spinal cord motor neurons in patients with sporadic ALS is fragmented and atrophic. In this study we show that spinal cord motor neurons of transgenic mice for an SOD1 mutation display a lesion of the Golgi apparatus identical to that found in humans with sporadic ALS. In these mice, the stacks of the cisternae of the fragmented Golgi apparatus are shorter than in the normal organelle, and there is a reduction in Golgi-associated vesicles and adjacent cisternae of the rough endoplasmic reticulum. Furthermore, the fragmentation of the Golgi apparatus occurs in an early, presymptomatic stage and usually precedes the development of the vacuolar changes. Transgenic mice overexpressing the wild-type human superoxide dismutase are normal. In familial ALS, an early lesion of the Golgi apparatus of motor neurons may have adverse functional effects, because newly synthesized proteins destined for fast axoplasmic transport pass through the Golgi apparatus.

Invariants for Families of Brieskorn Varieties

Fintushel and Stern have defined invariants for certain homology $3$-spheres which, if positive, show that the homology $3$-sphere cannot bound a positive definite $4$-manifold with no $2$-torsion in its first homology. In this note a number-theoretic formula is given for these invariants. It is used to show that all members of certain families of Brieskorn varieties have the same invariants, and hence exhibit the same nonbounding when one of the invariants is positive.

Invariants for families of Brieskorn varieties

Fintushel and Stern have defined invariants for certain homology 3 3 -spheres which, if positive, show that the homology 3 3 -sphere cannot bound a positive definite 4 4 -manifold with no 2 2 -torsion in its first homology. In this note a number-theoretic formula is given for these invariants. It is used to show that all members of certain families of Brieskorn varieties have the same invariants, and hence exhibit the same nonbounding when one of the invariants is positive.

Is Leukemia Caused by a Transmissible Virus?: A Working Hypothesis

Abstract 1. Leukemia, like other malignant tumors, has long been observed to occur more frequently among members of certain families than in the average population. This observation has been made not only in chickens, mice, and cattle, but also in humans. 2. Direct experimental evidence is now available suggesting that at least in chickens and mice, leukemia is caused by a filterable, submicroscopic agent, presumably a virus, transmitted from one generation to another directly through the embryos. 3. Although no experimental evidence is yet available concerning the nature of leukemia in cattle and in humans, the possibility should be considered that, as in chickens and mice, leukemia in other species may also be caused by a transmissible agent. In cattle, numerous observations have been made of leukemia developing in several members of the same family, in two or three successive generations. In humans, one case has been published in which three, and perhaps four, out of seven, and another in which five out of eight, siblings died from leukemia ; other observers have recorded leukemia developing in three successive generations in man. 4. The familial occurrence of leukemia and other malignant tumors in man and other species, could be explained by the following working hypothesis: there may exist a group of submicroscopic, cell-free oncogenic agents, individually distinct (some causing leukemia, others causing different malignant tumors), transmitted directly through the germinal cells from one generation to another. These agents would usually exist in an inactive form; in such a form, these agents would be frugal and moderate in their requirements, causing no apparent harm to their carrier hosts. Occasionally, however, prompted by as yet obscure but presumably varied trigger stimuli, these hitherto masked agents might change into formidable pathogens. Activated oncogenic agents would cause rapid multiplication of cells harboring them, resulting in the development of leukemia or other malignant new growth, and usually sealing the fate of their carrier hosts. Since, however, the activation of the oncogenic agent would usually occur in middle-aged hosts, the survival of the agent would have been already assured, the transmission of the agent to the host’s offspring occurring prior to the activation of the agent. Leukemia and other malignant tumors would therefore be essentially egg-borne virus diseases, like many other parasitic virus diseases of plants, insects, and birds. 5. On the basis of this working hypothesis, one could therefore regard the development of leukemia, or that of another malignant tumor, as the result of activation, frequently merely accidental, of an oncogenic agent, hitherto, masked, and carried by the host since birth. Since in many, perhaps in most, instances, the oncogenic agents would never become activated (though they would continue being transmitted from one generation to another), only now and then would leukemia, or another malignant new growth, develop in some of the members of certain families. Such instances, however, would usually be separated by one, two, or three generations of healthy individuals. 6. Since, therefore, two cases of leukemia (or other malignant tumors) representing successive links in the generation-to-generation transmission of the hypothetic virus in humans might frequently be separated by a century or two, the tracing of the epidemic course of the oncogenic agents in man would be extremely difficult, if at all possible, unless accurate records of cause of death would become available covering a sufficient number of successive generations. 7. Should this working hypothesis prove to be true, it would then follow that the number of individuals suffering from leukemia, or other tumors, would represent only a fraction of those actually carrying the seeds of either disease.

Carcinoma of the Breast in Homologous Twins

The role of heredity in disease has interested observers since early times. The recurrence of such diseases as hemophilia and peroneal atrophy in male members of certain families illustrates well the sex-linked hereditary character of these diseases. Likewise the direct inheritance of Huntington9s chorea seems well established. The part played by heredity in tumors has been less easy to trace, however. It is generally agreed that certain types of cancer can be hereditary in mice. Maud Slye (1) says: “That the occurrence of cancer has its basis in inherited susceptibility seems now to be satisfactorily established by the results obtained in many controlled breeding experiments.” Proof of the hereditary nature of the disease in man is less satisfactory. Macklin (2) gives a number of reasons why it is so difficult for observers to agree on this point. She reaches the conclusion that no matter what the mechanism of inheritance is, whether the tumor tendency is inherited as a single characteristic or whether it comes about by the influence of many factors, it is dependent on heredity. Among the arguments assumed to be in favor of the hereditary nature of tumors is the occurrence of similar tumors in similar positions in homologous twins. It is with this argument in mind that the following cases are reported.

Scientific Serials

Scientific Serials