Melittis melissophyllum L. from the family Lamiaceae is a wild perennial living in Europe. As a medicinal plant, it occurs only in folk medicine, with indications for digestive problems, insomnia and as an anti-inflammatory and antispasmodic agent. Modern phytochemical studies of extracts obtained from the aerial parts of Melittis melissophyllum have shown the presence of many biologically active substances that have long been known for their pharmacological medicinal properties. Their strong impact on the human body may justify the use of Melittis melissophyllum in unconventional therapies, and at the same time signals the possibility of extending the indications for medical applications. The use of Melittis melissophyllum extracts in the recipes of medicinal ointments accelerating the healing of wounds, pressure sores, burns and other skin damage, and showing antimicrobial effects comparable to traditionally used antiseptics, raises great hopes. Such studies are currently being conducted at the University of Medical Sciences in Bialystok. The presented article is a review of current literature on the potential use of Melittis melissophyllum L. for medicinal purposes. It is a pilot material for our further publications appearing as work progresses on discovering new therapeutic properties of this plant.