Background and Aims: To investigate the incidence and risk factors of stroke in hypertension patients over 60 years of age, and to investigate the correlation. Methods: A retrospective analysis of 454 hypertension patients who were diagnosed through examination were divided into 4 groups, of which included group A (hypertension plus type 2 diabetes) were 4 cases, group B (hypertension plus hyperlipidemia) were 367 cases, group C (hypertension plus type 2 diabetes and hyperlipidemia) were 47 cases, and group D (hypertension) were 36cases. Every patient was given observation after definite diagnosis and treatment of 54 months, and to investigate the incidence of acute cerebral infarction, cerebral hemorrhage. Results: There were 44 patients occurred acute cerebral infarction in all 4 groups. Of these cases, there were 1 case in group A, 31 cases in group B,10 cases in group C and 2 cases in group D. In group B, 3 cases occurred cerebral hemorrhage. Logistic regression analysis showed systolic blood pressure (OR=1.106, P=0.001), fasting glucose (OR=2.059, P=0.000) and low-density lipoprotein cholesterol (LDL-C) (OR=0.104, P=0.025) were risk factors for stroke. Conclusions: Higher levels of blood glucose and/or blood lipid associate with higher risk of stroke in patients with hypertension.