Medinilla Speciosa Research Articles

Pengaruh Metode Pengeringan Terhadap Aktivitas Antioksidan Ekstrak Etanol

Drying is the most important step to keep the compound stability in simplicia and is very influential to produce good quality igredients in the antioxidant activity contained in the simplicia. Antioxidants are oxidation-free inhibitors of free radical reactions. Parijoto is one of the plants that have antioxidant compounds.This study aims to determine the effect of drying, concentration of antioxidant activity of parijoto (Medinilla speciosa Blume) fruit. The drying method used is direct sunlight drying, indirect sunlight and oven. The antioxidant activity of ethanol extract on drying method was determined by 2,2 diphenyl-1-picrylhidrazyl (DPPH) method which is free radical. The qualitative test DPPH showed that the higher levels of ethanol extract from the three drying methods further diminished the color of DPPH solution in ethanol.The result showed thet the drying method gave different effect to the antioxidant activity of parijoto fruit which is significant(p0,05). Drying methods wich have high antioxidant activity are given by drying using oven method with an IC50 value 33,75µg/ml.

Antioxidant Activity of Parijoto Fruit Extract at Various Temperature of Food Processing

Parijoto (Medinilla speciosa) is a tropical plant that is used as traditional medicine by the community. This fruit contains many bioactive compounds. This study aims to analyze the effect of food processing temperature on the total phenolic compounds and antioxidant activity in parijoto extract. Tests are carried out at temperatures of 10, 30, 60, 75 and 100 ºC. Total phenolic compounds were analyzed by Folin-Ciocalteu method. Antioxidant activity were analyzed by DPPH (1,1-Diphenil-2-pikrilhidrazil) radical scavenging method. The results showed that the increased processing temperature causes a decrease in total phenolic compounds. This causes antioxidant activity to decrease. Processing at low temperatures is able to maintain the content of phenol compounds (33.02 μg/ml) and the greatest antioxidant activity.

PENGARUH EKSTRAK ETANOLIK BUAH PARIJOTO (Medinilla speciosa Blume) TERHADAP KADAR GULA DARAH DAN FUNGSI SEKSUAL TIKUS JANTAN GALUR WISTAR MODEL DIABETES MELLITUS KRONIK

ABSTRACTChronic diabetes mellitus is a disease of increased blood glucose levels in a long time so that it can affect sexual function such as damage spermatogenesis and aphrodisiac function. Parijoto has flavonoid content. This study aimed to determine the effect of ethanolic extract of parijoto (Medinilla speciosa Blume) fruit in blood glucose level and the sexual function in alloxan-induced diabetic male rats. The design of the study was post test only control group design, 25 male wistar rats aged 2 months with BB 100-200 gram divided into 5 groups. Group 1 (normal control), group 2 (negative control) induced alloxan 100mg / kgBB, groups 3, 4, and 5 were alloxan induced and administered EEBP at doses of 100 mg / kgBW, 250 mg / kgBW, and 500 mg / kgBW. Alloxan-induced rats were left for 4 weeks to achieve chronic DM. Data analysis of blood glucose level and spermatozoa quality using one way anova followed by LSD post hoc. While aphrodisiac of introducing and climbing using one way anova continued by LSD and coitus using kruskal wallis. The results showed that there were significant differences between negative control with normal group, III, IV, and V. The effect of ethanolic extract of parijoto fruit on blood glucose level and sexual function in alloxan-induced diabetic male rats showed no difference between treatment group of 100 mg / kgBW with negative group, and there were significant differences between treatment group of 250 mg / kgBW and 500 mg / kgBW with negative group. Ethanolic extract of parijoto fruit at dose 250 mg / kgBB and 500 mg / kgBB decrease blood glucose level, improve and increase sexual function in alloxan-induced diabetic male rats.

FORMULASI KRIM TABIR SURYA EKSTRAK BUAH PARIJOTO (Medinilla speciosa Blume) DAN UJI NILAI SPF SECARA IN VITRO

Sunscreen preparations are cosmetic preparations used as a protection to reduce the impact of sun exposure whose formulations contain active ingredients to absorb or diffuse sunlight, especially in areas of ultraviolet and infrared wave emissions. One of the potential natural ingredients for a sunscreen is parijoto fruit (Medinilla speciosa Blume). It contains flavonoid compounds that are able to prevent the harmful effects of UV rays. The objective of this research is to find out the formula of sunscreen cream of parijoto extract that meets the good physical quality of cream and to find out the result of SPF value test of parijoto fruit extract as sunscreen cream preparation in Vitro. The design of the study was experimental research conducted in the laboratory. The sample used in this research was parijoto made into thick extract by maceration method. Further, the viscous extract obtained was made to be a sunscreen cream and then tested either its physical evaluation or calculation of SPF value. The results of this study indicate that the preparation of sunscreen cream of parijoto fruit extract included in the extra protection category with the value is 6.66 and can be made into the good and stable preparations. The sunscreen cream of parijoto fruit extract has good physical properties and also has activity as UV protection in vitro.

Sitotoksisitas in vitro ekstrak etanolik buah parijoto (Medinilla speciosa, reinw.ex bl.) terhadap sel kanker payudara T47D

Background: Several studies focused on phytochemical as agents of cancer prevention and co-chemotherapy. One of Indonesian plant which has edible fruit but it hasn’t been completely explored is Medinilla speciosa (Reinw.ex Bl.). Objective : The aim of this study is to examine the cytotoxic activity (IC50 value) of Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract. Methods : Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract was used in this study. The cytotoxic activity was investigated in vitro on human breast cancer T47D cell-line. The cells viability were assessed using MTT colorimetric assay. Breast cancer T47D cell lines was treated with fruit ethanolic extract (10, 25, 50, 100, 250, 500 and 1000 µg/ml) for 24 hour of incubation. This study also identified phytochemical compound of the fruit with thin layer chromatography (TLC). Results: The result showed that ethanolic extract of Medinilla speciosa (Reinw.ex Bl.) has moderate cytotoxicity on breast cancer T47D cell line with IC50 value of 614.50 µg/ml and yield the decrease of cell viability at higher concentration. Medinilla speciosa fruit can not be used as anticancer agent but chemoprevention agent. Phytochemical test showed that the fruit extract contain flavonoid and saponin compound. Conclusion: Ethanolic extract of Medinilla speciosa fruit exhibited moderate cytotocicity on breast cancer T47D cell lines with IC50 value was 614,50 µg/ml thus it can be used as chemopreventioan agent.

Addition to the genus Medinilla (Melastomataceae) from Great Nicobar Biosphere Reserve

Medinilla speciosa (Reinw. ex Blume) Blume collected from the Campbell Bay National Park, Great Nicobar Island is reported here as a new record to the angiosperm flora of India. Brief description, illustration and photographs are provided.

The potency of Bukit Tapak forest as means for traditional ceremony, environmental conservation, and education

Bukit Tapak (1903 m) the natural reserve of Batukau I (816.4 ha) is one of three natural reserve area of Batukau (1762.8ha, 1974). Located at the tourism object of Bedugul, the eastern part boundaries to the Botanic Garden Eka Karya-LIPI(154.5 ha, 1959) and settlement of Candikuning area (1152 family, 4475 persons) and near the three lakes of the waterresources of Bali; Beratan, Buyan and Tamblingan lake. The special plants; cemara geseng (Casuarina junghuhniana Miq.),cemara pandak (Dacrycarpus imbricatus (Blume) de Laub.), nyabah (Pinanga arinasaensis J.R. Witono), paku kidang(Dicksonia blumei Planch.), and purnajiwa (Euchresta horsfieldii (Lesch.) Benth.). The pioneer plant of the hill is cemara geseng and the endemic is cemara pandak. The plant of needle leaves that basically the existence of Bali Botanical Garden as the conservation ex situ flora of noodle leaves especially at the eastern Indonesian area. Nyabah, which is supposed to be the new kind of palm named Arinasa, driven from the staff name who is the pioneer of the conservation. Paku kidang is rare. There are ethnobotany plants of ritual ceremony such as: kayu tulak (Schefflera sp.), kayu tulung (Brasaia sp.), penjalin (Calamus sp.), paku pidpid (Nephrolepis sp.), trijata (Medinilla speciosa (Blume ex Mart.) Blume), etc. Balinese people believe that forest is holly and sacred. But because of the existence of Pura Teratai Bang (16 century) at the slope, moslem cemetery (found in 1938) at the peak, and other needs (climbing, food, medicine, etc.), it can not be avoided the entrances of people that caused the forest is damaged. The forest reservation needs the approach to the local people, so the solution are morally and integration. The use of the forest which is potential as the environment education facilities conservation and other alternatives such as: horticulture, the improvement of the people economy discussed here to be the input for the forest conservation wisely and continuously.© 2004 Jurusan Biologi FMIPA UNS SurakartaKeywords: Bukit Tapak, traditional ceremony, environment, conservation, education.