Medicine Logistics Research Articles

Advancing Emergency Supplies Management: A Blockchain‐Based Traceability System for Cold‐Chain Medicine Logistics

AbstractAdvancing cold‐chain medicine logistics and emergency supplies management necessitates a robust blockchain‐based traceability system. This specialized information system is essential for enhancing quality control and operational efficiency. Despite challenges like insufficient supplies, ineffective distribution, and delays, blockchain's transparency and traceability offer significant potential to revolutionize national emergency management. This paper presents a blockchain‐based traceability system tailored for cold‐chain medicine logistics. This system achieves traceability and automatic medicine quality assessment by integrating blockchain principles and leveraging hazard analysis theory combined with IoT technology. This system also enhances data reliability with a multi‐sensor data fusion algorithm, improving temperature accuracy beyond conventional methods. Additionally, the feasibility and necessity of integrating blockchain into cold‐chain pharmaceutical traceability processes is thoroughly examined. The proposed system fulfills traceability needs for emergency cold‐chain medicine while addressing industry challenges.

Analisa Pengadaan dan Pengaruhnya Logistik Obat di RS Xyz Pamulang Berdasarkan Metode Abc Ven

This research analyzes the influence of factors that influence the efficiency of drug logistics at Permata XYZ Hospital. The research results show that drug procurement methods, procurement process efficiency, ABC VEN method, and staff training and expertise have a significant influence on drug logistics efficiency. Better procurement methods can improve the availability and use of medicines, procurement process efficiency contributes to efficient medicine logistics management, and the ABC VEN method helps reduce waste of resources and procurement costs. In addition, the training and expertise of medical and non-medical staff play an important role in managing drug supply, distribution and more efficient use of resources. Recommendations include increased transparency in the procurement process, automation of the procurement process, use of integrated information systems, better collaboration with drug suppliers, as well as investment in staff training in drug inventory management, use of information systems, and best procurement practices. These findings provide valuable guidance for Permata Pamulang Hospital in their efforts to improve operational efficiency and patient service.

Dynamic Uncertainty Study of Multi-Center Location and Route Optimization for Medicine Logistics Company

Multi-center location of pharmaceutical logistics is the focus of pharmaceutical logistics research, and the dynamic uncertainty of pharmaceutical logistics multi-center location is a difficult point of research. In order to reduce the risk and cost of multi-enterprise, multi-category, large-volume, high-efficiency, and nationwide centralized medicine distribution, this study explores the best solution for planning medicine delivery for the medicine logistics. In this paper, based on the idea of big data, comprehensive consideration is given to uncertainties in center location, medicine type, medicine chemical characteristics, cost of medicine quality control (refrigeration and monitoring costs), delivery timeliness, and other factors. On this basis, a multi-center location- and route-optimization model for a medicine logistics company under dynamic uncertainty is constructed. The accuracy of the algorithm is improved by hybridizing the fuzzy C-means algorithm, sequential quadratic programming algorithm, and variable neighborhood search algorithm to combine the advantages of each. Finally, the model and the algorithm are verified through multi-enterprise, multi-category, high-volume, high-efficiency, and nationwide centralized medicine distribution cases, and various combinations of the three algorithms and several rival algorithms are compared and analyzed. Compared with rival algorithms, this hybrid algorithm has higher accuracy in solving multi-center location path optimization problem under the dynamic uncertainty in pharmaceutical logistics.

Impact of COVID-19 pandemic on pharmaceutical systems and supply chain – a phenomenological study

BackgroundResilient pharmaceutical systems and supply chains are critical in the control of COVID-19, a pandemic that has mostly devastated public health systems and livelihoods in resource-limited countries in sub-Saharan Africa. ObjectiveTo evaluate the impact of COVID-19 on pharmaceutical systems and supply chain in a resource-limited setting. MethodsA descriptive qualitative survey using a phenomenological approach was conducted among key informants in the public and private pharmaceutical sectors of Namibia. Data were collected on the perceived impact of COVID-19 pandemic on the supply chain, as well as access and availability of essential medicines among the distributors and points of care in the private and public sectors. Qualitative themes of the impact were analyzed using Tesch's approach. ResultsOf the 21 key-informants, 57.1% were female and 85% were from the private versus the public pharmaceutical sector. Overall, key informants reported a negative impact on access and availability of essential medicines, particularly sanitation and hygiene products, and antimicrobials. Most medicine outlets, experienced longer lead times, attributed to reduced inter-country transportation of goods and services and limited in-country capacity and capabilities to manufacture. The main thematic challenges included bureaucratic bottlenecks and lack of emergency readiness of the medicine's logistics supply chain in Namibia. ConclusionCOVID-19 pandemic aggravated the inequitable access to essential medicines in the public and private sectors of Namibia. Governments in resource-limited countries need to strengthen in-country Private-Public Partnerships as well as regional treaties for Universal Health Coverage in context of the COVID-19 pandemic.

Management of Post-Disaster Medicine Logistics at the Pharmacy Installation of Regional Public Hospital Undata of Central Sulawesi Province

The purpose of this research is to fine out how the management of post-disaster medicine logistics at the Pharmacy Installation of Regional Public Hospital Undata the research. Method used was qualitative with in-depth interview data cullcolection techniques. Research informants were 6 informants who were determined by purposive sampling technique. The results show that the planning of pharmaceutical supplies at Regional Public Hospital Undata used consumtion methods epidemiology. The obstacles to logistical planning for type medicine, a disease tread is changing. Medicine logistics budget in pharmaceutical installations comes from the state budget and BLUD. Procurement of pharmaceutical supplies using the method of direct purchases and E-purchasing, obstacles in the procurement of medicine logistic are still arrears of payment of medicine to distributors. Slow distribution of medicine from distributors and the emtiness of medicine stocks acceptance of pharmaceutical supplies is carried out by the pharmaceutical installation warehouse staff and reception team, there are still obstacles in receiving the time for quality inspection and quantity of logistical goods wich quite long. Medicine logistics storage is carried out with the FIFO and FEFO systems with alphabetical storage arrangements, constraints in logistics storage, narrow IFRS repositories. Medicine logistics control was done by taking inventory to find out the quality and quantity of medicine as well as the medicine expired date, the obstacles in controlling medicine logistics time to take stock of hospitalization takes a long time.

Development of a Protocol for Cardiac Referral Transport Requests at a Pediatric Academic Center

Background: The process of triaging potential admissions at a busy academic center is logistically complex. Patients can originate from multiple sources including internal (emergency center, operating room, inpatient floor) and external (scene, non-pediatric facility, pediatric facility, colleague). The high number of physicians involved in accepting patients to the cardiac ICU or cardiology service introduces variability to the process and places undue stress on the system. Furthermore, the transport team can be strained when physicians unfamiliar with transport medicine physiology and logistics take lead on medical control for incoming patients. The aim …

0907 Implementation Of Pathway For Severe Obstructive Sleep Apnea Management In Children

Abstract Introduction Obstructive Sleep Apnea (OSA) is associated with neuro-cognitive, cardiovascular and metabolic morbidity in children. Adeno-tonsillectomy is the first line of treatment for OSA with PAP therapy and Oxygen supplementation being alternative therapeutic options in select cases. Severe Obstructive Sleep Apnea is a known risk factor for postoperative respiratory complications after adenotonsillectomy. Therefore, inpatient adenotonsillectomy with close monitoring is recommended for this group of children. Challenges to safe and timely care for this high risk group of children can be overcome with effective coordination of care between different locations and health care providers. Methods All children seeking treatment at Dayton Children’s Division of Sleep Medicine were managed through a pathway developed by a multi-disciplinary team involving sleep medicine, otolaryngology and clinical logistics. Severe OSA was defined as AHI ≥15 events/hr (children <2 year old), AHI ≥15 events/hr with three or more Oxygen desaturations <80% (children ≥2 to <6 years old), AHI ≥ 30 events/hr with three or more Oxygen desaturations <80% (Children ≥6 to 18 years old). Results A total of 78 children were diagnosed with severe OSA in 2019. All children were successfully triaged to appropriate therapeutic option (Adenonotonsillectomy, PAP, O2) within 24 hours of diagnosis. Urgent adenotonsillectomy was performed on the same day in 4 children and within 2 weeks on 12 children. There was no postoperative respiratory complication after urgent adenotonsillectomy. Thirteen children had adenotonsillectomy after 2 weeks. PAP therapy was started in 28 children (34%). Therapy was initiated on the same day in 10 children and the next day on one child. Oxygen supplementation was started in 21 children (27%). Conclusion A multidisciplinary collaborative approach can result in delivery of timely and safe care for severe OSA in children. Support NA

Third-Party Cold Chain Medicine Logistics Provider Selection by a Rough Set-Based Gained and Lost Dominance Score Method

Choosing third-party cold chain logistics suppliers can be regarded as a multiple criteria group decision-making problem since multiple aspects of suppliers are required to be evaluated by multiple experts. This paper aims to address the problem of selecting the optimal third-party cold chain medicine logistics provider considering the uncertainties caused by the qualitative criteria that are difficult to accurately evaluate and the limitation of experts’ knowledge and cognition. We propose a rough set-based gained and lost dominance score method in which experts are supposed to use linguistic terms to express their information. First, we combine rough numbers with linguistic scale functions to depict the semantics of linguistic terms and convert the formal expression information of linguistic terms into numerical information, which has an advantage of expressing imprecision and subjective judgments of experts. In addition, given that different experts often have different emphases on different attributes, we investigate a rough set-based gained and lost dominance score method in which experts have different weights for different criteria. Finally, an illustrative example of selecting the optimal third-party cold chain medicine logistics is given with comparative analysis, showing the efficiency of the proposed method. This method provides a new way to solve the selection problem of third-party logistics suppliers.

Securing E-health Networks from Counterfeit Medicine Penetration Using Blockchain

This paper attempts to explain a solution to tackle the problem of counterfeit medicines in India by proposing a resilient electronic health networks using blockchain. The distribution and consumption of fake medicines take thousands of lives every year. There are no effective measures to combat the network of the fake medicine syndicate in the country, and the stakeholders in the healthcare ecosystem have to work under trust-deficit relationships amongst them. Blockchain is a decentralized system of computer nodes, where each node stores the same data, and coexist with other nodes without having to trust them. The proposed solution is based on recording the medicine logistics requirements from medicine manufacturing to the patient on the blockchain network. If, at any stage, counterfeit medicine is introduced into the system, it will be detected immediately, and its further penetration will be stopped. The system is simulated using a hyper ledger fabric platform, and its performance is also compared with other existing methods. Results show that the system thus formed is computationally intensive but offers a reliable solution to the menace of fake medicines.

\u201cThe system here isn\u2019t on patients\u2019 side\u201d- perspectives of women and men on the barriers to accessing and utilizing maternal healthcare services in South Sudan

BackgroundIn fragile and war-affected setting such as South Sudan, a combination of physical environmental, socioeconomic factors and healthcare’s characteristic contributes to higher rates of home delivery attended by unskilled attendants. This study aims to understand the community members’ experience, perceptions and the barriers in relation to accessing and utilizing maternal healthcare services in South Sudan.MethodsWe conducted in-depth one-on-one interview with 30 women and 15 men to investigate their perspectives on the barriers to access maternal and child health related services. We purposively selected women and their partners in this study.ResultsOur study revealed that inadequate quality of antenatal care services such as lack of essential medicine, supplies and tools was linked to individual’s mothers dissatisfaction with the services they received. In addition, sudden onset of labor and lack of safety and security were important reasons for home delivery in this study. Furthermore, lack of transport as a result of a combination of long distance to a facility and associated costs either restricted or delayed women reaching the health facilities.ConclusionsOur study highlighted an urgent need for the government of South Sudan to implement security and safety measures in order to improved access to delivery service at night. Incorporating private transports to provide access to affordable and reliable transport services for pregnant and post-partum women is also important. Increasing the budget allocation for medicine and health supplies and improving management of medicine and supply chain logistics are essential.

Research on the Current Situation and Strategy of E-commerce Development of Chinese Medicinal Materials in Gansu Province

At present, there are some problems in e-commerce of Chinese medicinal materials in Gansu Province, such as insufficient awareness of the development of business entities, loss of regional brand advantages, great differences in the quality of Chinese medicinal material commodities, and empty trading platform. This paper proposes to strengthen the brand building, establish a unified standard, pay attention to personnel training, speed up the construction of network platform and the Chinese medicine logistics system.

Conceptions on pharmaceutical services in Brazilian primary health care.

ABSTRACTOBJECTIVE To identify and discuss the conceptions of pharmaceutical services in Brazilian Primary Health Care, according to different subjects.METHODS This study is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos – Serviços, 2015 (PNAUM – National Survey on Access, Use and Promotion of Rational Use of Medicines – Services, 2015), which is composed of an information survey in a representative sample of cities, stratified according to Brazilian regions, and a subsample of primary health care services. Municipal secretaries of health, those responsible for pharmaceutical services, and those responsible for medicine delivery in pharmacies/dispensing units of the selected services were interviewed. The questionnaires included one question about the understanding of the interviewee regarding pharmaceutical services. The content analysis technique was used to apprehend, in the statements, the meanings attributed to pharmaceutical services, which were subsequently classified into categories according to their main conceptions.RESULTS Among the wide diversity of conceptions on pharmaceutical services (PS), we highlight the ones focused on 1) logistic control of medicines with activities concerning guidance or information on their use and 2) guidance or information to users on the use of medicine. The findings reveal a shifting tendency from a medicine-focused conception to one that considers the users and their needs as the final recipient of these actions. However, the lack of references to conceptions regarding care management and integrality point out the slowness of this change; after all, this is a social and historical process that comprises the production of meanings that transcend legal, logistic, and technical arrangements in pharmaceutical services.CONCLUSIONS The diversity of conceptions expresses the several meanings attributed to pharmaceutical services; we also identified, in their reorientation process, a movement that reflects a gradual shift in the technical paradigm, from the focus on medicine logistics to a user-oriented approach of health services.

Logistics planning for hospital pharmacy trusteeship under a hybrid of uncertainties

This paper presents two medicine logistics planning models by using a time-space network approach, one with deterministic variables and the other with stochastic variables. Flow dependent variable costs, random demand and random service time are featured in our models in addressing economies of scale and uncertainties in a real-world medical logistics problem. Effective computational schemes are designed, and an evaluation method is proposed to derive and assess a solution to the models. Numerical tests are conducted and show promising results for applications to a real-world problem.

Multi-stage emergency medicine logistics system optimization based on survival probability

Multi-stage emergency medicine logistics system optimization based on survival probability

Chinese Herbal Medicine Warehouse Management and Control Integration System Design

Chinese herbal medicine is the quintessence of the Chinese nation. However, Chinese herbal medicine processing, warehousing, distribution mode is relatively backward. Lack of appropriate industry standards, cause its quality and safety is a great hidden danger. The development of Chinese herbal medicine logistics is also in urgent need to follow the pace of the times, to meet the growing needs of the people. Storage is a very important part of the Chinese herbal medicine, a reasonable and appropriate storage can make the value and efficacy of medicinal materials are well preserved. Information management system, equipment automatic control system and operation safety monitoring system integrated storage management and control integrated systemi¼ŒBased on shared informationi¼Œthe storage efficiency of Chinese medicinal materials is improved, and it provides the basis for the information tracing system of Chinese herbal medicine. system

Chinese Herbal Medicine Warehouse Management and Control Integration System Design

Chinese herbal medicine is the quintessence of the Chinese nation. However, Chinese herbal medicine processing, warehousing, distribution mode is relatively backward. Lack of appropriate industry standards, cause its quality and safety is a great hidden danger. The development of Chinese herbal medicine logistics is also in urgent need to follow the pace of the times, to meet the growing needs of the people. Storage is a very important part of the Chinese herbal medicine, a reasonable and appropriate storage can make the value and efficacy of medicinal materials are well preserved. Information management system, equipment automatic control system and operation safety monitoring system integrated storage management and control integrated systemi¼ŒBased on shared informationi¼Œthe storage efficiency of Chinese medicinal materials is improved, and it provides the basis for the information tracing system of Chinese herbal medicine. system

Rational use of medicines – Indian perspective!

India, the largest democracy in the world, is with a federal structure of 29 states and 7 union territories. With a population of more than 1.2 billion, resource is always a constraint and so is in the health system too. In the federal structure, providing healthcare is largely the responsibility of state governments. Medicines are important component of health care delivery system and quality care is dependent on the availability and proper use of quality medicines. In spite of being known as pharmacy of the third world, poor access to medicines in the country is always a serious concern. Realizing the need of quality use of medicines, several initiatives have been initiated. As early as 1994, seeds of rational use of medicines were sown in the country with two initiatives: establishment of a civil society, Delhi Society for Promoting Rational Use of Drugs (DSPURD) and establishment of government agency in Tamil Nadu, a southern state, called Tamil Medical Services Corporation Limited (TNMSCL). DSPUD was in official association with World Health Organization Country Office for implementing essential medicine programme in the country for two biennia. In addition to organizing sensitising and training programme for healthcare professionals throughout the country, it looked after the procurement and appropriate use of medicines in Delhi government health facilities. TNMSCL has made innovations in medicine management including procurement directly from manufacturers as a part of pooled procurement, establishing warehouses with modern storage facilities and Information Technology enabled management of whole process. TNMSCL Model is now replicated in almost the entire country and even in some small other countries as it is successful in improving access to medicines.The National Government and the State Governments have developed strategies to promote rational use of medicines as a part of improving access and quality care in public health facilities. National Government developed policies and regulations for combating antimicrobial resistance, controlling the prices of medicines, establishing generic medicines stores and advocating for the need for improvement of medicine logistics at state level and prescription auditing system. There is wide variation in medicine procurement and management system among the states. Spending on medicines ranges from as small as 2% of health budget to as high as 17%. The procurement system varies from individual facilities to partial pooled procurement to complete centralised system.There are attempts of developing essential medicine lists, standard treatment guidelines and costing of treatment of common illnesses. Except for the few states, essential medicine list remains an ornamental showpiece. However, with apex court's intervention, the prices are now controlled for all 348 medicines listed in national list. The pharmaceutical companies continue to violate price regulations either through making the medicines at different strengths or new fixed dose combinations (FDCs). Perhaps the largest number of FDCs and many of them with no valid justification are available in the country. Decisions on compulsory licensing have made the new anticancer medicines affordable. Other countries have also benefited from this decision. While some progress has been made for appropriate use of medicines in public health facilities, there are little efforts in private sectors and at community levels. Availability of prescription medicines without much control and free drug advertising are other concerns. Like all other countries irrational use of medicines continues to be of concern in India despite of several attempts of improving use of medicines both in the health system as well as in community. But efforts continue to be made for improving the use of medicines!

Suggestions to strengthen quality management of herbal decoction pieces——based on production chain of herbal decoction pieces

With the development of society and the improvement of people's living standards, the effect of Chinese medicine in treatment and health care is more and more prominent. The herbal decoction pieces are the important part of Chinese medicine,it can be applied directly to clinical treatment and it's also the raw material of Chinese patent medicine. Therefore, the quality of herbal decoction pieces is quite important. The parts of the production of herbal decoction pieces are numerous, and there are possibilities of adverse effects on the quality of the herbal decoction pieces in every part. In this paper, we based on the production chain of herbal decoction pieces, analyzed the main problem that affect the quality of herbal decoction pieces in the part of selection of Chinese herbal medicines, planting, purchasing, processing, packaging, storage and transport, such as the poor quality of seed and seedlings of plant-based Chinese medicines, some plants left their place of origin and have been introduced in the place that is not suitable for this kind of plant, the insufficient growth time and the excessive harmful substances. The purchasers and the accepters lack of professional knowledge and professional ethics. The mechanism of processing is not clear, the standards can not be uniformed, and lack of qualified person in processing, etc. So we suggest: intensify the basic research of key scientific issues. Improve the quality of persons who work in herbal decoction pieces; Establish an "integration" mode of operation in herbal decoction pieces enterprise; Breeding high quality plant resources, establish the large-scale planting basement; Make the packing of herbal decoction pieces standard; Establish the modernization traditional Chinese medicine logistics enterprise.

Study on Optimization of Cargo Space Allocation Based on Jointown Pharmaceutical Logistics Center

With the rapid development of modern logistics technology and automation of information technology, the AS/RS has been more and more widely used in the field of medicine logistics. In order to more effectively manage AS/RS, improve the rationality of the layout, reduce the number of goods handling and storage costs, it demands to optimize the cargo space allocation for goods .This article adopts multi-objective genetic algorithm to solve the optimization problem of cargo space allocation modeling, and use Jointown pharmaceutical logistics center as an example to further verify the analysis, getting the ideal optimization results and the simulation image.

A Web Service Enabled Framework for RFID Applications

RFID can give a unique digital identifier to real physical object, and bridges the physical world with the virtual digital world. Based on the analysis on our experience of RFID applications, some common key issues and requirements of RFID application are presented. A lightweight framework based on Web Service to support ubiquitous RFID application of medicine logistics is designed and implemented. This lightweight framework provides the integration of RFID technology and other holistic applications. Virtual object is used to map the real physical world object and the virtual digital object. Experiment result is given and some future research directions are discussed.