Use Of Medicines Research Articles

Pharmacognostic, phytochemical and pharmacological activities of Ocimum kilimandscharicum Guerke

The family Lamiaceae encompasses a diverse array of therapeutic plants, with the genus Ocimum being particularly esteemed. The plant known as Kapur Tulsi in India, Ocimum kilimandscharicum Guerke is a perennial woody shrub characterized by its essential oil, which predominantly contains camphor, along with linalool, limonene, eugenol, 1,8-cineole, and camphene. This review aims to provide current information on the taxonomy, botany, distribution, ethnomedicinal uses, phytochemistry, pharmacology, and toxicological profile of O. kilimandscharicum. The information presented was critically analyzed to understand the current research on this species and to explore potential future opportunities for this plant in pharmaceutical research. A comprehensive literature search was conducted and relevant information was collected through an extensive exploration of bibliographic databases, including Google Scholar, ScienceDirect, PubMed, Web of Science, Semantic Scholar, Europe PMC, and Scopus. The literature suggests that the plant contains a range of compounds that underpin its broad spectrum of pharmacological effects. These phytoconstituents have been widely employed in the treatment and management of numerous conditions. This review consolidates the latest information on its phytochemical and pharmacological activities, traditional applications, and scientific research. The review highlights the significant phytoconstituents of Ocimum kilimandscharicum Guerke and summarizes the evidence supporting its pharmacological potential. The findings suggest that the plant's diverse compounds contribute to its extensive use in traditional medicine and underscore its potential for therapeutic applications in various diseases.

Preserving Stem Cells for Potential Use in Future Reparative Medicine

With its enormous potential for regenerative medicine and therapeutic applications, stem cell preservation represents a major breakthrough in biomedical science. Stem cells are gathered, processed, and stored under carefully monitored circumstances in order to preserve their viability for potential use in the future. Because they may differentiate into a variety of cell types, stem cells—especially those derived from sources like umbilical cord blood—are essential for both therapeutic and research uses. An essential function of cord blood banking is to offer a plentiful supply of immune system cells that may be stored for potential future therapeutic applications. Immunological deficits, osteoarthritis, Parkinson's disease, and heart failure are just a few of the conditions for which stem cell treatments have shown promise. Notwithstanding the promise, there remain obstacles such immunological rejection and the need for more research to fully comprehend the development and functionality of stem cells. It is essential for the general public to be informed about stem cell treatments and cord blood banking in order for expectant parents to make well-informed decisions. Future advancements in the subject depend heavily on resolving ethical issues and enhancing the effectiveness of stem cell-based therapies. To fully realise the promise of stem cell preservation in conventional medicine, more research, creativity, and international cooperation are required.

Calibration of discrete meta-parameters of bamboo flour based on magnitude analysis and BP neural network.

In the research and development of technology and equipment for bamboo products deep processing, such as filling, drying, and medicinal use of bamboo flour (BF), the poor compaction and fluidity of BF materials entails the need for accurate discrete element model (DEM) and BF parameters to provide a reference for the simulation of BF processing operationsand the development of related equipment. The average particle size of the 5 types of BFs ranges from 0.136 mm to 0.293 mm, and the small particle size of BF particles causes to the number of BF particles in bamboo processing equipment to reach tens of millions or even billions. When conventional methods are used for simulation, ordinary computers cannot provide the required computing power. To address the aforementioned challenges, this paper proposes a calibration method for the discrete element contact parameters of BFs based on dimensional analysis and a back propagation (BP) neural network. Using particle scaling theory and dimensional analysis methods, the average particle size of the BF was increased to 1 mm, and the main discrete element contact parameters of the five types of BF to be tested were used as input layers. The injection method and sidewall collapse method were used to obtain the angle of repose (AR) as the output layer. Fifty groups were randomly selected using MATLAB for EDEM simulation, and the simulation results were trained using the BP neural network algorithm; an ideal neural network model was obtained, the discrete element parameters of different BFs were predicted, and physical experiments were performed to verify two types of AR and mold hole compression under calibrated parameters. The relative error between the simulated AR obtained through calibration parameters and the physical experimental values is less than 2.3%. Through BF parameter validity verification, the simulated maximum compression displacement and compression ratio after stabilization were 34.81 mm and 0.477, which were close to the actual experimental results of 34.77 mm and 0.461, respectively, verifying the accuracy of the neural network prediction model. The research results provide a reference for the simulation of BF processing operations and the development of related equipment.

Prodromal Phase of Idiopathic Generalized Epilepsy: A Register-Based Case Control Study.

Idiopathic generalized epilepsy (IGE) is associated with distinct behavioral traits, symptoms of frontal lobe dysfunction, and psychiatric comorbidity. Whether psychiatric symptoms are part of the IGE endophenotype or secondary to the burden of chronic disease is unknown. In this study, we aimed at describing the sequence of appearance of psychiatric and epilepsy symptoms in patients with IGE. Inclusion criteria for this cohort study were diagnosis of IGE with age at diagnosis at 10-25 years. We created 2 mutually exclusive cohorts, 1 based on ICD-10 codes in Danish registers with a first IGE diagnosis from January 1, 2005, to December 31, 2018, and a second patient cohort treated at Odense University Hospital and the Danish Epilepsy Centre in the same period. Each case was matched with 10 age-matched, sex-matched, and geography-matched normal population controls from the Danish registers. We compared social status, health care utilization, and psychiatric diagnoses between the groups in the 5 years preceding epilepsy diagnosis, at diagnosis, and at the end of the study period using the Wilcoxon rank-sum test and confirmatory logistic regression models. We identified 1,009 patients for the register-based cohort (55.1% female; mean age at diagnosis [SD]: 15.9 [±3.8] years) and 402 patients for the hospital-based cohort (56.2% female; mean age at diagnosis [SD]: 18.3 [±7.4] years) and matched them to 10,090 and 4,020 controls, respectively. IGE cohorts and controls did not differ at birth. In the 5 years before their IGE diagnosis, register patients had an increasing number of contacts with hospitals (mean visits [SD]: cases: 8.3 [±5.6], controls: 6.6 [±4.5]) and their general practitioners (mean visits [SD]: cases: 48.7 [±26.3], controls: 45.3 [±24.5]) and received more prescriptions for psychiatric medications (prescriptions: cases: 4.2%, controls: 2.5%, p = 0.003) compared with controls. Patients had a higher rate of psychiatric comorbidity (comorbidity: cases: 26.5%, controls: 17.8%, p < 0.0001) at the end of the study than controls. Data were similar in the hospital-based cohort. Our data suggest a prodromal phase of IGE detectable approximately 5 years before the first seizure characterized by increased health care utilization and greater use of prescription medicine for psychiatric symptoms.

Exploring the material basis and molecular targets of Changma Xifeng tablet in treating Tourette syndrome: an integrative approach of network pharmacology and miRNA analysis.

This study was to investigate the mechanism of Changma Xifeng tablet, a traditional Chinese medicine in the treatment of Tourette syndrome. Network pharmacology was utilized to pinpoint blood-entering constituents of Changma Xifeng and explore their potential targets. Additionally, differential microRNA expression analysis was conducted to predict Tourette syndrome-associated targets, complemented by molecular docking and dynamics simulations to support the interactions of the active compounds with these targets. The study identified 98 common targets between Changma Xifeng and Tourette syndrome, which may be involved in the treatment process. A protein-protein interaction network and a drug-active ingredient-disease target network highlighted the formulation's multi-component, multi-target therapeutic approach. Eight pivotal targets-AR, GRM5, MET, RORA, HTR2A, CNR1, PDE4B, and TOP1-were identified at the intersection of microRNA and drug targets. Molecular docking revealed 12 complexes with favorable binding energies below - 7kcal/mol, specifically: AR with Alfacalcidol, TOP1 with Albiflorin, GRM5 with Arachidic Acid, GRM5 with Palmitic Acid, AR with Arachidic Acid, AR with 2-Hydroxyoctadecanoic Acid, RORA with Pinellic Acid, RORA with Palmitic Acid, AR with Acoronene, AR with Epiacoronene, AR with 4,4'-Methylenediphenol, and HTR2A with Calycosin. Our molecular docking and molecular dynamics simulations suggest potential stable interactions between the formulation's active components and target proteins. These computational methods provide a preliminary theoretical framework that will guide our future experimental work. The study provides a scientific rationale for the use of traditional Chinese medicine in Tourette syndrome management and offers new insights for drug development.

Gastroprotective Efficacy of North African Medicinal Plants: A Review on Their Therapeutic Potential for Peptic Ulcers

ABSTRACTPeptic ulcer disease remains a prevalent gastrointestinal disorder worldwide. Current treatments often have limitations, sparking interest in alternative therapies from medicinal plants. This review examines the gastroprotective potential of 54 North African medicinal plants against peptic ulcers. An extensive literature search was conducted, focusing on plants with preclinical and clinical evidence of anti‐ulcer efficacy and documented use in North African traditional medicine. The review identified several promising plant species, such as licorice (Glycyrrhiza glabra), chamomile (Matricaria chamomilla), olive (Olea europaea), pomegranate (Punica granatum), Aloe vera, and black seed (Nigella sativa), along with their bioactive constituents, including flavonoids, tannins, and terpenoids. These compounds exhibit gastroprotective properties through multiple mechanisms, such as enhancing the gastric mucosal barrier, inhibiting acid secretion, displaying antioxidant and anti‐inflammatory effects, promoting ulcer healing, and combating Helicobacter pylori infection. The evidence presented includes in vitro assays, animal models, and some clinical studies. While many of the 53 plants reviewed demonstrated significant anti‐ulcer effects compared to standard drugs, further clinical research is needed to establish efficacy and safety in humans. The synergistic actions of phytochemical mixtures in medicinal plant extracts likely contribute to their therapeutic potential. This review highlights the role these North African medicinal plants may play in the prevention and treatment of peptic ulcers and identifies promising candidates for further research and development of evidence‐based botanical therapies.

Cultural and socio-demographic drivers shape seahorse uses in Malaysia: implications for conservation

Abstract Seahorses Hippocampus spp. are commercially and culturally important to many communities. Although seahorses are widely used in traditional medicine, as curios and as aquarium fishes in Southeast Asia, documentation on the current nature and extent of culturally motivated seahorse uses in Malaysia is lacking. To examine how ethnicity and other socio-demographic drivers shape traditional medicinal use and underlying cultural beliefs involving seahorses, we administered a questionnaire-based survey during March 2021–April 2022 to members of the general public and fishers in Malaysia. Approximately one-fifth (21.0%) of respondents reported consuming seahorses (34.4% of these used seahorses for medicinal purposes, 55.2% for other non-medicinal uses and 10.4% for both types). Consumers of seahorses were from all ethnic groups except for Indigenous groups. In the general public group, medicinal use was more common amongst the Chinese respondents, whereas in the fisher group, other uses were more common amongst the Malay respondents. Amongst the threats facing seahorses, which include overfishing, habitat destruction, bycatch and ocean plastic pollution, only bycatch was perceived as a major threat by most of the general public and fisher respondents. The relatively low prevalence of reported seahorse use amongst Malaysians is an encouraging finding from a conservation perspective. However, the high proportion of non-medicinal uses indicates the need to focus on such other uses to ensure the sustainability of seahorse use in Malaysia.

Effectiveness of Patient Medication Counseling in a Tertiary Care Hospital: A Cross-Sectional Study

Background: Medicine is prescribed to help the patient. But it can cause unwanted effects in the patient if one take too much or multiple medicines that don’t go together. Many patients have problems each year, some serious, because of taking the wrong medicine or not taking the right medicines correctly. This cross-sectional study was done to assess the effectiveness of patient medication counseling in a tertiary care hospital. Methods: This cross-sectional questionnaire-guided study was carried out in the dispensary of a tertiary care hospital, from January to April 2024. convenient sampling technique was employed to select study participants. Results: A total of 540 respondents were included in this study. Only 50.3% of the participants knew the correct frequency and dose of the prescribed medications. Majority of the patients did not knew the indications of the medication they were taking. Conclusion: There is a need to strengthen the patient medication counselling process so that patients understand &amp; remember what have been advised during counselling. As a healthcare provider, it is our responsibility to educate the patient about the prescribed medicines to obtain the positive healthcare and ensure safe use of medicines.

Evaluation of the Wound Healing Potential of Aloe Vera Leaf Extract Containing Carbopol 934 as a Gelling Agent and Comparing with Sodium CMC and HPMC on Surgically Induced in Wound Wister Rats: A Preclinical Study

ABSTRACT Introduction: The restricted injury can occur in any tissue or organ and is caused by an external source. The toughness and adaptability of the delivery system are enhanced by the synthetic hydrophilic, biocompatible, and biodegradable stable polymer known as carbopol 934. Aloe vera is a plant belonging to the Liliaceae family that releases anthraquinones, a bitter liquid that has medicinal qualities. Aim: The current study is to determine if aloe vera gel containing Carbopol 934 can cure wounds in animal models used in experiments. Need of the Study: This review will offer a thorough examination of recent studies on the medicinal use of Aloe vera gel. Further study is required to establish the mechanism of action because certain areas, such as wound healing, have not received much attention in the scientific community. However, these biological materials must first be appropriately isolated and identified. Materials and Methods: Various centralizations of Carbopol 934, sodium CMC, and HPMC will be attempted, and lastly, gel that showed great spreadability and consistency will be chosen for wound mending properties of homegrown Aloe vera gel.

Synergistic role of prebiotics and probiotics in gut microbiome health: Mechanisms and clinical applications

AbstractPrebiotic and probiotic usage has exploded, with most formulations promoting gastrointestinal and immunological benefits. Prebiotics modulate the gut microbiota, as a result, short‐chain fatty acids are released into the bloodstream. Prebiotics have immunomodulatory properties that reduce inflammation while enhancing immune responses and boosting gut health. The potential of probiotics has shown steady expansion in the digestive system, metabolic balance, and vaginal health. Probiotics offer therapeutic and preventative strategies for a range of human diseases. The in vitro studies suggested the delivery matrix might influence their effects through physicochemical interactions with molecular and cellular structures as well as modifications in cellular expression. Dietary fibers and polyphenols both contribute significantly to human health protection and can ferment in the gut microbiota to create butyrate. This comprehensive review aims to highlight the probiotics and prebiotics, and provide evidence to support their use in preventive and therapeutic medicine. It is anticipated that it will help the clinical and preclinical research to look into the effects of inclusion and processing on their activity in different food delivery formulations. There are potential opportunities needed to enhance immunological and digestive health by comprehending and using the interaction between the gut microbiota and the immune system in our diet.

AUTOMEDICAÇÃO ENTRE ESTUDANTES UNIVERSITÁRIOS DA ÁREA DA SAÚDE NO BRASIL: UMA REVISÃO INTEGRATIVA DA LITERATURA

This study aimed to investigate, through an integrative review of the literature, the main reasons that lead undergraduate students in the health area to self-medicate, since they have the responsibility to guide society on the appropriate use and medicine insurance. After applying the inclusion and exclusion criteria, eleven studies were selected in which it was identified that, among the variables that influenced the practice of self-medication that were mentioned at least once in the productions, the most frequent were self-knowledge, advice from third parties, previous medical concession and ease of access. It is argued that undergraduate students in the health area are a portion of the population who self-medicate in an exacerbated manner, mainly because they believe they have sufficient theoretical, technical and scientific knowledge to carry out such practice. Thinking about this serious public health problem, we can see that there is a lack of data to promote effective measures in the rational use of medicines. It is necessary to understand that the idea of ​​integrated health care comprises knowledge developed collectively by professionals, teachers, managers and users/patients, co-responsible for the production of health, so that self-medication can be responsible for all segments of health. society.

Antimicrobial Resistance: What Lies Beneath This Complex Phenomenon?

Antimicrobial Resistance (AMR) has evolved from a mere concern into a significant global threat, with profound implications for public health, healthcare systems, and the global economy. Since the introduction of antibiotics between 1945 and 1963, their widespread and often indiscriminate use in human medicine, agriculture, and animal husbandry has led to the emergence and rapid spread of antibiotic-resistant genes. Bacteria have developed sophisticated mechanisms to evade the effects of antibiotics, including drug uptake limitation, drug degradation, target modification, efflux pumps, biofilm formation, and outer membrane vesicles production. As a result, AMR now poses a threat comparable to climate change and the COVID-19 pandemic, and projections suggest that death rates will be up to 10 million deaths annually by 2050, along with a staggering economic cost exceeding $100 trillion. Addressing AMR requires a multifaceted approach, including the development of new antibiotics, alternative therapies, and a significant shift in antibiotic usage and regulation. Enhancing global surveillance systems, increasing public awareness, and prioritizing investments in research, diagnostics, and vaccines are critical steps. By recognizing the gravity of the AMR threat and committing to collaborative action, its impact can be mitigated, and global health can be protected for future generations.

Complementary and Alternative Medicine Use among Cancer Patients in Iraq

Complementary and Alternative Medicine Use among Cancer Patients in Iraq

3D Bioprinting for Engineered Tissue Constructs and Patient-Specific Models: Current Progress and Prospects in Clinical Applications.

Advancements in bioprinting technology are driving the creation of complex, functional tissue constructs for use in tissue engineering and regenerative medicine. Various methods, including extrusion, jetting, and light-based bioprinting, have their unique advantages and drawbacks. Over the years, researchers and industry leaders have made significant progress in enhancing bioprinting techniques and materials, resulting in the production of increasingly sophisticated tissue constructs. Despite this progress, challenges still need to be addressed in achieving clinically relevant, human-scale tissue constructs, presenting a hurdle to widespread clinical translation. However, with ongoing interdisciplinary research and collaboration, the field is rapidly evolving and holds promise for personalized medical interventions. Continued development and refinement of bioprinting technologies have the potential to address complex medical needs, enabling the development of functional, transplantable tissues and organs, as well as advanced in vitro tissue models.

Maternal and neonatal factors’ effects on wharton's jelly mesenchymal stem cell yield

As Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) are easily accessible, easy to isolate, and ethically acceptable, they represent a promising source of MSCs for use in regenerative medicine. Considering decisions on WJ-MSCs collection requires extensive knowledge of the factors that impact their yield. This study's aim was to evaluate the influence of parameters related to mothers and newborns on the WJ-MSCs yield. The WJ-MSCs were isolated and expanded after being isolated from 79 umbilical cord (UC) samples. Population doubling time and cell proliferation were assessed. By flow cytometry analysis, WJ-MSCs were identified by positivity of CD105, CD90, and CD73 and negativity of CD45 and CD34. There was a statistically significant negative correlation between UC width and P1 doubling time. Maternal age and WJ-MSC yield were shown to be negatively correlated. Birth weight and gestational age showed a significant positive correlation between WJ-MSCs yield and neonatal variables. No significant correlations were detected between the WJ-MSCs and the mother parity, nor the neonatal sex, fetal presentation, or head circumference. The WJ-MSCs yield increases with younger maternal age, higher gestational age, and increased neonatal birth weight. Hence, consideration should be given to these factors when selecting the ideal donors.

Formulation and Evaluation of Controlled Release Tablet Using Thyme and Rosemary for Osteoporosis

Osteoporosis is a common public health problem which currently affected millions of people worldwide. Osteoporosis is mainly associated with Ovarian hormone deficiency following menopause is till now a most common reason of age-related bone loss. There are tablets that are available in the market, which shows the side effect such as nausea, heart burn, gastric problem after the continuous use of medicine. These side effects led to the avoidance of such medicine. Using herbal plant such as thyme and rosemary as an alternative of those drug will help to reduce these effects. Hence, selected to develop a Controlled Release Tablet of Rosemary and Thyme. Tablet is the most popular among all dosage forms existing today because of its convenience of self-administration, compactness and easy manufacturing. Developing the tablet using thyme and rosemary in the form of controlled release drug will help to prolonged the effect of the medicine. As precision of dosing, to improve the bioavailability of the drug and to maintain the constant level of drug in the plasma become important to provide the long-term effect to the patient. It will also provide the patience compliance as well as prolonged the effect of drug in the patient’s body.

Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid.

Chrysin (CHR) is a naturally occurring flavonoid found in the human diet, recognized for its potential in preventing neurodegenerative diseases. However, its limited water solubility restricts its bioavailability and therapeutic applications. To address this issue and bolster the neuroprotective properties of CHR for potential nutraceutical or medicinal use, we investigated a novel compound, LQFM280, formed by conjugating CHR with β-d-glucose tetraacetate. We conducted both in vitro (using SH-SY5Y cells, mutant STHdhQ111/Q111 cells, and wild-type STHdhQ7/Q7 cells), and in vivo (mice) neurotoxicity experimental model induced by 3-nitropropionic acid, which mimic biological changes akin to Huntington's disease in humans. Compared to non-glycosylated CHR, LQFM280 showed superior in vitro effects in preventing neurotoxicity caused by increased mitochondrial vulnerability due to mutant huntingtin. In vivo findings demonstrated that LQFM280 has heightened efficacy in mitigating weight loss, memory and locomotor impairment, oxidative stress, and disruptions in the antioxidant defense system, as well as succinate dehydrogenase, and cholinesterase activities induced by 3-nitropropionic acid. These findings underscore the significant enhancement of chrysin's neuroprotective effects through glycosylation with β-d-glucose tetraacetate, positioning it as a promising candidate for use as a nutraceutical or food supplement to promote health benefits.

Anthropocentrism in Contemporary Chinese Dictionary: A Synergic Perspective of Critical Lexicographical Discourse Studies and Systemic Functional Linguistics

Abstract Critical Lexicographical Discourse Studies (CLDS) view the dictionary as a discourse and emphasize an ideological, ethico-political dimension to the lexicographical process. Combining CLDS with Systemic Functional Linguistics, this paper looks into how anthropocentrism is manifested linguistically in Contemporary Chinese Dictionary (Seventh Edition), the most influential authoritative general-purpose Chinese dictionary, by examining the transitivity and appraisal patterns in the definition texts concerning animals and plants. The analysis shows that animals and plants are seldom assigned agency in their own right and that the animals and plants are evaluated either positively or negatively according to whether they are useful to the human beings while their intrinsic value is ignored. In particular, animals are highlighted for their agricultural and medicinal use and plants for their medicinal and ornamental value. However, compared with its previous editions, the dictionary has shown an enhanced awareness of environmental protection by deleting the encyclopaedic information that describes the use of some rare animals’ meat, bones and fur. It is argued that, although modern general-purpose dictionaries are increasingly corpus-based and descriptive, their role in shaping social values and stances cannot be disregarded. Dictionary makers need to balance what words mean with what they can be said to mean or be allowed to mean (Moon, 2014). The study contributes to unmasking and denaturalizing the hidden ideology in colony texts such as the dictionary, enhances a critical use of dictionaries and helps develop the theory of critical lexicography and emerging ecolexicography.

Potential Use of Organoids in Regenerative Medicine.

In vitro cell culture is crucial for studying human diseases and development. Compared to traditional monolayer cultures, 3D culturing with organoids offers significant advantages by more accurately replicating natural tissues' structural and functional features. This advancement enhances disease modeling, drug testing, and regenerative medicine applications. Organoids, derived from stem cells, mimic tissue physiology in a more relevant manner. Despite their promise, the clinical use of regenerative medicine currently needs to be improved by reproducibility, scalability, and maturation issues. This article overviews recent organoid research, focusing on their types, sources, 3D culturing methods, and applications in regenerative medicine. A literature review of "organoid" and "regenerative medicine" in PubMed/MEDLINE highlighted relevant studies published over the past decade, emphasizing human-sourced organoids and their regenerative benefits, as well as the availability of free full-text articles. The review uses descriptive data, including tables and text, to illustrate the challenges and potential of organoids in regenerative medicine. The transition from 2D to 3D models, particularly organoids, has significantly advanced in vitro research. This review covers a decade of progress in various organoid types-such as liver, cholangiocyte, intestinal, pancreatic, cardiac, brain, thymus, and mammary organoids-and their 3D culture methods and applications. It addresses critical issues of maturity, scalability, and reproducibility and underscores the need for standardization and improved production techniques to facilitate broader clinical applications in regenerative medicine. Successful therapy requires increased scalability and standardization. Organoids have enormous potential in biological research, notwithstanding obstacles.

Challenges in integrating traditional Chinese medicine and gut microbiota research for insomnia treatment

The gut microbiome is an extensive variety of bacteria with a range of metabolic capabilities that can be pathogenic, beneficial, or opportunistic. Changes in the gut microbiota's composition can affect the link between gut integrity and host health as well as cause disruptions to numerous neurological systems. The second most prevalent mental health problem, insomnia has a negative social and economic impact. Currently, it is becoming increasingly obvious how crucial it is to preserve the delicate balance of gut microbiota to treat illness-related symptoms like insomnia. Although traditional Chinese medicine has proposed an effective strategy against insomnia through gut microbiota alteration in animal models, studies in human models are limited. This decreases the predictive value of the studies in terms of human outcomes. This editorial places an emphasis on cultural sensitivity rather than scientific reasoning that promotes the use of traditional Chinese medicine (TCM). We aim to emphasize the concern that promoting TCM could divert resources from conventional medical research, leading to suboptimal care.