The Unmanned Aerial Vehicle (UAV) has been used for the delivery of medical supplies in urban logistical distribution, due to its ability to reduce human contact during the global fight against COVID-19. However, due to the reliability of the UAV system and the complex and changeable operation scene and population distribution in the urban environment, a few ground-impact accidents have occurred and generated enormous risks to ground personnel. In order to reduce the risk of UAV ground-impact accidents in the urban logistical scene, failure causal factors, and failure modes were classified and summarized in the process of UAV operation based on the accumulated operation data of more than 20,000 flight hours. The risk assessment model based on the Bayesian network was built. According to the established network and the probability of failure causal factors, the probabilities of ground impact accidents and intermediate events under different working conditions were calculated, respectively. The posterior probability was carried out based on the network topology to deduce the main failure inducement of the accidents. Mitigation measures were established to achieve the equivalent safety level of manned aviation, aiming at the main causes of accidents. The results show that the safety risk of the UAV was reduced to 3.84 × 10−8 under the action of risk-mitigation measures.
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