Medical simulation is a practical field of education. Its indirect goal is to inspire and connect specialists responsible for various roles in simulation centers. Medical simulation is a highly developed professional field which, along with the development of educational paths, has become a permanent part of the didactic process. Therefore, the audience of the conference consisted of everyone who starts or continues a career in the field of medical simulation. “Science has no homeland because human knowledge covers the whole world.” Therefore, we should remember that everything we have learned and taught our students: professionalism, understanding, empathy, humanity, not only in medical areas, will be lost if we are not able to find application for this knowledge. We are aware that the implementation of a medical simulation is a long process, often raising many questions and prompting all of us to make an effort that gives didactic and scientific satisfaction. Taking into account this challenge related to the creation of Medical Simulation Centers in the disciplines of medicine, nursing, obstetrics and paramedics, dentistry, physiotherapy or pharmacy, we meet the needs of the teaching staff of our universities. Sharing good practices and our own very valuable experience is principal goal for today and building a network of medical simulation centers mutually supporting this task for tomorrow and the nearest common future. Therefore, the II International Conference “Medical Simulation-Practical Applications and Technologies” (11th–12th March 2022, http://medsim2022.bok-ump.pl) brings together enthusiasts of modern medical education and simulation, experts and specialists. The event is organized in Poznan at the Poznan University of Medical Sciences in close cooperation with the Pomeranian Academy in Slupsk, the Polish Nursing Society and the Polish Society of Medical Simulation. That meeting was dedicated such important issues as: • New tools in medical simulation education • Organizing the osce exam • “in-situ” medical simulation • Experiences and best practices