Medical Screening Research Articles

Global Origin and Spatiotemporal Spread of Hepatitis C Virus Epidemic Genotypes/Subtypes: A Complete Genome-Based Phylodynamic and Phylogeographic Analyses.

Hepatitis C virus (HCV) is a pathogenic virus of global health concern. The phylodynamics of HCV genotypes/subtypes 1a, 1b, 2, and 3 are explored only for specific geographic regions. However, their genome based global origin and detailed spatiotemporal spread, have yet to be extensively studied. To study the global evolution of "epidemic" HCV genotypes/subtypes, we screened all available HCV complete genome sequences (n = 2744) from 27 countries worldwide for over four decades. We used representative sequences (n = 516) for phylodynamic and phylogeographic analyses, examining HCV worldwide origin, transmission, and spatiotemporal spread. We are the first to study the global phylogeography of genotype 2. The evolutionary rates for genotype/subtype 1a, 1b, 2, and 3 are 1.109 × 10-3, 1.096 × 10-3, 5.013 × 10-3 and 1.483 × 10-3 substitutions/site/year respectively. We deduced tMRCAs and origin location of respective HCV genotype/subtype as 1909.21 (United States), 1893.36 (Japan), 981.76 (France), and 1714.89 (India). We estimated their migration pattern with time to and from different continents. The origin location of genotype 2 was estimated to be France instead of previous postulated African origin. This can be related to slave trade, French colonization, and previous studies on specific geographic regions only. HCV genotypes/subtypes showed transmission and expansion due to factors like World War II, iatrogenic infections, "baby boomer" population, inefficient medical screening, intravenous drug use, decline due to antiviral therapy introduction. Our study provides novel and extensive information about the evolutionary history and spatiotemporal spread of the HCV genotypes responsible for most infections worldwide.

Dental Treatment Patterns in Pediatric Patients with Rare Diseases: A Retrospective Analysis at Yonsei University Dental Hospital

This study aimed to investigate dental treatment patterns in pediatric patients with rare diseases at Yonsei University Dental Hospital over 3 years. Data of 786 pediatric patients diagnosed with rare diseases who received dental treatment between January 2020 and December 2022 were analyzed retrospectively. Patients were identified through electronic medical record screening for rare disease codes registered with the Korea Disease Control and Prevention Agency. Demographics, rare disease categories, and dental treatment methods and modalities were analyzed using chi-square tests, Fisher’s exact tests, t-tests, and logistic regression. Significant differences in dental treatment needs and methods were observed among categories. Patients with nervous system diseases were less likely to receive preventive or restorative treatments, such as sealants (<i>p</i> = 0.0062) and composite restoration (<i>p</i> = 0.0171), and had a higher prevalence of disabilities (<i>p</i> < 0.00001), leading to greater dental care challenges. Conversely, patients with congenital malformations required more extensive treatments, including stainless-steel crowns (<i>p</i> = 0.0118) and surgery (<i>p</i> = 0.0234), often under general anesthesia (<i>p</i> = 0.0337). The study underscores the importance of tailored dental care protocols and interdisciplinary collaboration to address the needs of pediatric patients with rare diseases, enhancing their oral health outcomes and quality of life.

Medical mistrust and receptivity to lung cancer screening among African American and white American smokers

ABSTRACT Although medical mistrust is associated with lower cancer screening uptake among racial minorities, such as African Americans, potential impacts on cancer screening among White Americans are generally understudied. In this study, we examined links from medical mistrust to lung cancer screening among African American (N = 203) and White American (N = 201) smokers. Participants completed the Group-Based Medical Mistrust Scale and viewed a brief online educational module about lung cancer risks, etiology, and screening. Thereafter, participants reported their receptivity to lung cancer screening using a Theory of Planned Behavior (TPB) measurement framework (attitudes, normative beliefs, perceived control, and intentions). Medical mistrust predicted lower screening receptivity across all TPB measures for both racial groups. Although medical mistrust was higher among African Americans, there were no race differences in screening receptivity. However, there was some evidence that race moderates the relationship between medical mistrust and screening attitudes. While greater mistrust predicted more negative attitudes among both races, this effect was stronger among White Americans than African Americans. Findings suggest that group-based medical mistrust is a barrier to lung cancer screening for both African Americans and White Americans and illustrates the need to address medical mistrust as a barrier to screening for both racial minority and nonminority populations.

School entry examinations in the former German Democratic Republic (GDR) from 1949 to 1989 - An overview of formal and content-related implementation

Summarising the formal and substantive enrolment practice of school entry examinations (SEU) in the German Democratic Republic (GDR). Through a systematic literature review using a conventional as well as internet-based sources, specialised literature on specific topics and original documents were made available following selected search terms to capture essential characteristics of SEU in the GDR and to present them in a general context. In the GDR, regular school enrolment took place at the age of 6, although SEU implementation practice during the 1950s and 1960s was fundamentally inconsistent in terms of form and content. On the basis of mandatory annual screening examinations for children, the medical screening examination at pre-school age of 5-6 years was formally valid as a SEU. On a case-by-case basis, the responsible paediatricians carried out supplementary, but non-standardised developmental tests. From the 1970s onwards, the increasing density of kindergarten in the GDR led to their specialist staff getting more involved in the assessment of pre-school children's competences relevant to schooling. In addition, screening at the age of 4-5 years also became more relevant for developmental diagnostic purposes. While various examination procedures were initially used, a standardised inventory of instruments for assessing learning ability, intellectual development and language development gradually emerged during the 1970s. These two staggered SEUs between the age of 4 and 6 years enabled preschool children to be supported if necessary, so that children with developmental delays could be given adequate developmental and educational opportunities. This concept also enabled an intensifying, partly informal cooperation between the specialist staff in the kindergartens, paediatricians, parents and school headmasters. Overall, the SEU in the GDR was based on a professionally and a well thought-out concept from the 1970s onwards. At this time, the standardised, staggered and multidisciplinary approach was methodologically superior to school enrolment practice in West Germany.

Large-Area Metal-Organic Framework Glasses for Efficient X-Ray Detection.

Cutting-edge techniques utilizing continuous films made from pure, novel semiconductive materials offer promising pathways to achieve high performance and cost-effectiveness for X-ray detection. Semiconductive metal-organic framework (MOF) glass films are known for their remarkably smooth surface morphology, straightforward synthesis, and capability for large-area fabrication, presenting a new direction for high-performance X-ray detectors. Here, a novel material centered on MOF glasses for highly uniform glass film fabrication customized for X-ray detection is introduced. MOF glasses, composed of zinc and imidazole derivatives, enable the transition from solid to liquid at low temperatures, facilitating the straightforward preparation of large-area and continuous MOF films with high mobility for X-ray device fabrication. Remarkably, MOF glass detectors demonstrate an exceptional sensitivity of 112.8 µC Gyair -1 cm-2 and a detection limit of 0.41 µGyair s-1, making them one of the most sensitive and with the best detection limits reported to date for MOF X-ray detectors. Clear X-ray images are successfully conducted using these developed MOF glass detectors for the first time. This breakthrough in X-ray sensitivity, and detection limit along with the spatial imaging resolution establishes a new standard for developing large-area and efficient MOF-based X-ray detectors with practical applications in medical and security screening.

Review on the development of the organoids

Abstract. Organoids, a novel field, were first experimentally supported in 2007 and began to be engineered around 2020. Organoids can be developed from stem cells or organ progenitor cells through the process of differentiation, or they can be created by changing the alignment of pluripotent stem cells throughout the process of cell differentiation. Organoids are exploited for the purpose of scientific research in the areas of human development, illness, screening of medications, and gene therapy. The study utilized a literature review method to examine the evolution of organoid production, new application, and technological advancements. Organoids have advanced from basic tissue engineering organs to being used for modeling diseases and providing more therapeutic options. Their progress is noteworthy and has the potential to be a significant approach in biological medicine research in the future.

A qualitative study of patient and family experiences in adolescents with varicoceles: A focus on fertility, self-esteem, and sexual function

A varicocele is an abnormal dilation of the pampiniform plexus of veins in the scrotum that commonly affects postpubertal males. The condition has been associated with male infertility, testicular hypotrophy, and pain. However, the clinical experiences of adolescent patients and their families regarding the evaluation, surveillance, and management of varicoceles have not been previously examined. This study explores the patient's and family's experiences of varicocele diagnosis and subsequent management to better understand the salient factors impacting decision-making and care. We conducted semi-structured interviews with patients and their families between August 2022 and January 2023. A total of 39 participants (16 adolescent males and 23 parents) were recruited following varicocele diagnosis and treatment at an urban, tertiary care hospital in California. Purposive sampling was adopted for the recruitment of participants through medical record screening to identify eligibility. Utilizing a modified grounded theory approach through the use of constant comparison and memo writing, the analysis consisted of open coding, axial coding, and selective coding, resulting in the production of core concepts and categories. Results demonstrate that parents and adolescents can benefit from improved understanding and education about long-term expectations during the diagnosis and treatment of adolescent varicoceles. Qualitative analysis indicates: 1) parents and adolescents have common concerns regarding fertility; however, this is exacerbated by the complexity of medical decision-making being dependent on adolescent and parental understanding of the full scope of varicocele impacts and outcomes, and 2) the psychosocial impact of a varicocele on adolescent self-esteem and sexual function are significant drivers for seeking care, which often manifested through discussions on masculinity through notions of 'manhood' and future sexual performance. Discussions with patients and families largely focused on their concerns regarding fertility, sexual function, and aesthetics (impacting self-esteem); however, their primary concern was for the need for more accurate and comprehensive information, which includes the natural history of the condition and the full scope of treatment options. Future studies should examine the experiences of patients and families from diverse backgrounds and geographic locations to identify potential differences in experiences. Findings identified the need for potential improvement in communication between pediatric urologists and families to alleviate anxiety and uncertainty among patients and families and empower them to make informed decisions about their care.

Novelty Classification Model Use in Reinforcement Learning for Cervical Cancer.

Cervical cancer significantly impacts global health, where early detection is piv- otal for improving patient outcomes. This study aims to enhance the accuracy of cervical cancer diagnosis by addressing class imbalance through a novel hybrid deep learning model. The proposed model, RL-CancerNet, integrates EfficientNetV2 and Vision Transformers (ViTs) within a Reinforcement Learning (RL) framework. EfficientNetV2 extracts local features from cervical cytology images to capture fine-grained details, while ViTs analyze these features to recognize global dependencies across image patches. To address class imbalance, an RL agent dynamically adjusts the focus towards minority classes, thus reducing the common bias towards majority classes in medical image classification. Additionally, a Supporter Module incorporating Conv3D and BiLSTM layers with an attention mechanism enhances contextual learning. RL-CancerNet was evaluated on the benchmark cervical cytology datasets Herlev and SipaKMeD, achieving an exceptional accuracy of 99.7%. This performance surpasses several state-of-the-art models, demonstrating the model's effectiveness in identifying subtle diagnostic features in complex backgrounds. The integration of CNNs, ViTs, and RL into RL-CancerNet significantly improves the diagnostic accuracy of cervical cancer screenings. This model not only advances the field of automated medical screening but also provides a scalable framework adaptable to other medical imaging tasks, potentially enhancing diagnostic processes across various medical domains.

Provision of basic swimming and water safety skills in low-resource environments: barriers and facilitators of use of WHO practical guidance

IntroductionWHO guidance supports implementation of drowning prevention interventions. This study aimed to examine barriers and facilitators of use of WHO guidance on basic swimming and water safety skills in low-resource...

Barriers to Family History Collection and Family Medical Screening Recommendation in the Sudden Death in the Young Case Registry.

Sudden death in the young (SDY) poses a public health problem affecting thousands of individuals annually in the United States. The SDY Case Registry utilizes existing infrastructure of death investigation programs, including medical examiner/coroner (ME/C) systems, to enhance understanding of SDY causes and risk factors to inform prevention strategies. This includes identifying and promoting screening recommendations for at-risk family members. To explore barriers to family history collection and familial screening recommendation procedures across Registry sites, nine individuals from seven SDY sites were interviewed. Interviews focused on logistics, methods to address barriers, and recommendations for improvements. Despite variability in practices, data analysis revealed three common themes related to barriers of these processes: (1) timing and grief, (2) lack of family history in medical records, and (3) families lost to follow-up. This study offers insights into these processes within the Registry and sheds light on broader practices within the death investigation domain. Data analysis led to recommendations for the improvement of these practices including the prioritization of three key family history questions during the initial death investigation by a designated individual in each office/system.

Key contextual factors involved with participation in medical and genomic screening and research for African American and White Americans: a qualitative inquiry.

Tremendous progress has been made promoting diversity in recruitment for genomic research, yet challenges remain for several racial demographics. Research has cited intertwined fears of racial discrimination and medical mistrust as contributing factors. This study aimed to identify key factors to establishing trust in medical and genomic screening and research among African Americans and White Americans. Participants completed online focus groups and resulting transcripts were analyzed using a qualitative descriptive approach, with content analysis methods based on recommendations by Schreier. Fifteen African Americans and twenty-three White Americans participated in the study, 63% of which were female. The mean age of participants was 38.5 (SD = 16.6). The Overarching Theme of Trust is Context Dependent was identified, along with the following five themes describing elements influencing trustworthiness for our participants: (1) Professional Experience, Education, and Training Bolster Trust; (2) Trust Depends on Relationships; (3) Cross-checking Provided Information is Influential in Establishing Trust; (4) Trust is Undermined by Lack of Objectivity and Bias; and (5) Racism is an Embedded Concern and a Medical Trust Limiting Component for African Americans. To effectively address mistrust and promote recruitment of diverse participants, genomic research initiatives must be communicated in a manner that resonates with the specific diverse communities targeted. Our results suggest key factors influencing trust that should be attended to if we are to promote equity appropriately and respectfully by engaging diverse populations in genomic research.

Asymptomatic bacteriuria screening for developing countries using a modified water quality test kit.

Between 2% and 15% of pregnant women unknowingly experience asymptomatic bacteriuria (ASB), defined as ≥105 CFU per milliliter of urine in the absence of symptoms. ASB increases the risk of adverse pregnancy outcomes including pyelonephritis, preterm labor, and low-birth weight infants. While pregnant women in the United States are routinely screened for ASB, those in developing countries with limited resources and funding lack an accurate mechanism for ASB screening. Aquagenx water quality test kits detect Escherichia coli, the most common causative agent of ASB, and total coliform bacteria in drinking water via colorimetric and fluorescent indicators. We found that the Aquagenx system is compatible with human urine and then proceeded to develop an ASB screening protocol using disposable inoculating loops. Our protocol diagnosed artificial ASB- samples (104 CFU/mL E. coli) with a false positive (FP) rate of 33% (n = 18) and ASB+ (105 CFU/mL E. coli) with a false negative (FN) rate of 5.6% (n = 18). Clinical sample testing with our protocol revealed a FP rate of 0% in ASB- samples (n = 28) and a FN rate of 0% in ASB+ samples caused by coliforms (n = 13). Aquagenx did not detect ASB in nine clinical samples with non-coliform etiological agents due to the limitations of the technology. However, with very high accuracy for detection of E. coli and other causative agents that collectively account for 90.1% of ASB cases, these kits could be used as a diagnostic ASB screening tool in developing countries in which there is currently no alternative to urine culture.IMPORTANCEAsymptomatic bacteriuria (ASB) affects 2%-15% of pregnant women and can result in adverse maternal and fetal outcomes if left undetected and untreated. In the United States and other developed nations, pregnant women are regularly screened for ASB via urine culture. However, in low-resource countries where bacterial culture is not available, dipstick testing is used. Although accurate in cases of symptomatic bacteriuria, dipstick detection is ineffective for detecting ASB. Here, we made use of an existing water quality field test for ASB urine screening, which would be readily deployable in low-resource settings. We optimized a dilution protocol for sampling patient urine within the detection limits of the Aquagenx kit technology. Overall, we were able to detect ASB samples with Gram-negative pathogens that collectively account for 90% of all ASB cases. Utilization of this repurposed technology for proactive medical screening may help prevent adverse pregnancy and birth outcomes due to ASB.

Predictors for psychosocial consequences of screening for liver diseases in Germany: a LASSO approach

Abstract Background Medical screening is extensively used across various disciplines for early disease detection and prevention of severe progression aiming to reduce disease-specific burden, improve quality of life and promote health. However, screening is debated due to unclear evidence of its overall benefits from a public health perspective. Screening is associated with improved health behavior and cost-effectiveness. However, studies identified adverse effects of screening like psychosocial burden. Most results originate from cancer screening and it is unclear whether they are transferable to other contexts. Within a research program, a systematic screening procedure to detect patients with liver cirrhosis at early stage in an asymptomatic general population was evaluated. In this study, we aimed to identify patient characteristics that predict and explain variance in psychosocial outcomes of screened patients. Methods This study analyzed data from 523 participants who underwent a systematic liver disease screening in Germany from Jan 2018 to Feb 2021. We used bootstrapped LASSO regression with 10-fold validation to evaluate the influence of various predictors on the outcomes measured by the Psychological Consequences of Screening Questionnaire (PCQ). The constructs measured by the PCQ are social, physical and emotional dysfunction associated with screening. Results We identified lower severity of comorbidities, higher subjective social status, stronger social support, older age, better critical health communication skills and higher health literacy as relevant predictors of lower psychosocial dysfunction, indicating their protective role in preventing psychosocial burden of screening. Conclusions From a public health perspective, medical screening offers should take into account patients’ individual context regarding their subjective social status, health impairments, personal social networks and health literacy skills to reduce post-screening psychosocial burden. Key messages • Social support, age, health literacy and higher subjective social status were positively associated with lower psychosocial consequences of liver screening. • The findings indicate that liver screening should be carried out, taking into account the individual’s situation and resources available.

Multidisciplinary approach to asylum seekers health assessment: a 5-year experience in Modena, Italy

Abstract Background Asylum seekers’ well-being represents a global health issue. They face significant challenges to their physical and mental health due to their migratory path. In the Modena province (Northern Italy), a multidisciplinary approach has been applied to the care of asylum seekers by Department of Public Health (DPH), with a team of specialists in infectious diseases, dermatology, gynaecology, obstetrics, psychology and preventive medicine. Asylum seekers receive a first visit, including medical and psychological assessment and screening for infectious diseases. Ad hoc pathways are also active for asylum seekers who need secondary-level care. This study aims to investigate the health status of asylum seekers referred to Modena Centre. Methods This cohort study enrolled asylum seekers hosted in Modena between November 2018 and May 2023. During the first visit, personal and anamnestic data were collected aided by cultural mediators, along with clinical assessment. Furthermore, Tuberculin-Skin-Test (TST) and blood tests for HBV-HCV-HIV-Syphilis were performed. Results A total of 646 migrants were included, 94% were males with a median age of 26 years (range: 15-50), the majority from Bangladesh (39%). Females were mostly from Ivory Coast (36%), median age of 30 years (range: 17-45). Most conditions were treated at the primary care level and were related to cutaneous disease (22%), only 11% of subjects required second-level diagnostics. Positive TSTs were 41% (N = 265). Of them, 55.5% (N = 147) also tested positive for QuantiFERON-TB. Screening for infectious diseases revealed positivity rates of 4% for HBsAg, 1% for HCVAb, 0.8% for HIV and 1.4% for TPPA+RPR. Conclusions The multidisciplinary approach is the innovative and strength point of this protocol for asylum seekers’ health ensuring prompt management of pathologies after their arrival. Moreover, data collection is useful for improving intake services and implementing public health programs for vulnerable individuals. Key messages • The innovation of this protocol for asylum seekers’ health lies in its multidisciplinary approach. • Clinical data collection will support health policies’ choices to protect vulnerable individuals.

Heavy Work Investment (HWI) and Its Effect on Employees’ Physical and Mental Health

Abstract Background Economic reality and centrality of work have led to employees investing much time and effort in work. However, The number of hours spent at work may not be the only explanation, and other characteristics, such as type of work, employees’ personality, economic status, motivations, etc., need to be considered. The Heavy Work Investment model (Snir & Harpaz, 2012) considers these variables and classifies employees into four types of investors. This study examines the physical and mental health consequences of each HWI group. Methods Participants (N = 962) were workers who came to a medical center for annual medical screenings. About 70% were males, and the average age was 50.13 years (SD = 9.53). They divided into 5 groups: Typical full-time workers (N = 208, 29.2%), ‘Needy’ (N = 111, 15.6%), ‘Employer directed’ (N = 111, 15.6%), ‘Workaholic’ (N = 192, 26.9%) and ‘Work devoted’ (N = 91, 12.7%). The personal data was cross-referenced with the respondents’ health data. Differences for categorical variables were examined with Chi-square analyses. Results ‘Employer-directed’ employees, more than ‘work-devoted’ employees, perceived their health status as preventing them from performing mild activities. ‘Employer-directed’ and ‘needy’ employees, more than ‘work-devoted’ employees, perceived their health status as interfering with their social activities and their pain as interfering with their regular activities. ‘Workaholic’ employees suffered from more diseases than ‘work-devoted’ employees, and they were found to be 3.70 times more likely to be at a high risk of cardiovascular disease than typical full-time workers. Conclusions It is possible to anticipate types of health damage according to occupation type and develop occupation-adjusted health promotion programs. It is necessary to base labor laws on protecting employees’ health, particularly regarding time and workload’ outside of work’ in both hours (additional or flexible) and location (hybrid work). Key messages • Inspire organizations to be aware of potential injuries caused by HWI and promote the creation of intervention programs, potentially significantly improving employees’ health and well-being. • Evidence for the necessary laws that protect employees’ health, particularly regarding time and workload ‘outside of work’ in both hours (additional or flexible) and location (hybrid work).

Factors associated with a history of acute traumatic cycling injuries in 60 941 cycling race entrants in South Africa: SAFER study XLII

BackgroundInformation on acute traumatic cycling injuries (ATCIs) in the 12 months prior to entry in a cycling race and the predisposing factors have not been well-researched.ObjectiveDetermine factors associated with a...

Health information and the timing of social security benefit entitlements

This study examines whether new health information obtained through medical screening affects entitlements to Social Security benefits. Random assignment of information is derived from a unique feature of the Continuous National Health and Nutrition Examination Survey. The survey data are matched to administrative data from the Social Security Administration. The results suggest that new health information led to delays in benefit entitlements, particularly among workers near the early entitlement age. The results are consistent with employment lock, whereby workers delay retirement and continue to work to obtain employer-provided health insurance.

Epidemiological overlaps in COVID-19 and malaria within healthcare and community settings of Southern Ghana.

COVID-19 disruptions including lockdowns and prioritization of COVID-19 control programs in Africa in 2020-2022 contributed to reductions in malaria control activities including malaria diagnosis, treatment and resistance monitoring. This study investigated the malaria burden and distribution on the background of active transmission of SARS-CoV-2 in Southern Ghana; utilizing community health education and medical screening (CHEMS) approach to determine epidemiological overlaps in COVID-19 and malaria. Between October-December 2022, prospective cross-sectional surveys, with CHEMS were conducted in Greater Accra and Central regions, where 994 participants enrolled either at a hospital or community setting provided demographic and clinical data including history of clinical malaria infection and antimalarial treatment in the past 2 weeks. Of this study population, 953 provided nasal/throat swabs for COVID-19 RT-PCR testing, with a subset of 136 participants also providing finger-prick blood for malaria RDT testing. The study population comprised of 73.6% adults, with 54.6% COVID-19 vaccination rate. Overall, 18.1% of participants had a history of clinical malaria, which was associated (adjusted odds ratio > 1.50, p-value ≤0.022) with COVID-19 symptoms and positivity, study area and hospital setting, suggestive of overlaps in the epidemiological risk for malaria. On a background of widespread SARS-CoV-2 infections (12-37%), malaria parasitaemia was detected in 6%, with 2% being co-infections with SARS-CoV-2. Among the malaria positives, 9.5% had a history of antimalarial treatment, which suggested that their infections were recrudescent parasitaemia. The epidemiological and clinical overlap between malaria and COVID-19 within the hospital and community settings underscores the need for accurate case diagnosis to inform effective clinical treatments. Innovative surveillance programs, with community engagement are needed to maximize control interventions including treatment of asymptomatic malaria infections.

Early-stage breast cancer screening using a new biodegradable and easily implantable multi-element sensor in sub-THz range

In this article, a new biodegradable and easily implantable multi-element sensor is presented for early-stage breast cancer screening within the Sub-THz frequency range. The evolution of the sensor begins with the development of a single element. Once the desired operating frequency of operation is accomplished by the single element it is transformed into a multi-element configuration. The sensor is implemented on a compact size (20,000 × 20,000 µm2) easily biodegradable cordura substrate. The sensor performance is evaluated in terms of in-band reflection, directivity and surface current. The sensor is offered Factional Bandwidth (FBW), average directivity and surface current density 115.15%, 10.5 dBi and 20 A/m, respectively. The breast phantom screening is carried out for normal and malignant phantoms of (Tis, N0, M0), (T1, N0, M0) and (T2, N1, M0) using the proposed Multi-Element Sensor (MES). The Principal Component Analysis (PCA) results, error bar and sensitivity parameters are accounted for in the analysis to discriminate the normal phantom from malignant phantoms. The sub-THz range of operation of the proposed sensor has opened a new research scope for medical screening applications and the proposed method comparatively, offers a wide range of measurements for tumour detection.

309 Novel Addition of Point-of-Care Ultrasound to Medical Screening Exam for Obstetric Patients Reduces Time to Diagnosis of Ruptured Ectopic Pregnancy

309 Novel Addition of Point-of-Care Ultrasound to Medical Screening Exam for Obstetric Patients Reduces Time to Diagnosis of Ruptured Ectopic Pregnancy