Abstract

Abstract. Organoids, a novel field, were first experimentally supported in 2007 and began to be engineered around 2020. Organoids can be developed from stem cells or organ progenitor cells through the process of differentiation, or they can be created by changing the alignment of pluripotent stem cells throughout the process of cell differentiation. Organoids are exploited for the purpose of scientific research in the areas of human development, illness, screening of medications, and gene therapy. The study utilized a literature review method to examine the evolution of organoid production, new application, and technological advancements. Organoids have advanced from basic tissue engineering organs to being used for modeling diseases and providing more therapeutic options. Their progress is noteworthy and has the potential to be a significant approach in biological medicine research in the future.

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