Medical School Affiliation Research Articles

Role of intercellular adhesion molecule-1 in adhesion and migration of mesenchymal stem cells in ankylosing spondylitis and its mechanisms

Objective: To investigate the role and underlying mechanisms of intercellular adhesion molecule-1 (ICAM-1) in the adhesion and migration of mesenchymal stem cells (MSCs) in patients with ankylosing spondylitis (AS). Methods: Bone marrow and ligament tissues were collected during surgery from patients with AS and thoracolumbar fractures (as controls, HC) treated from October 2021 to October 2022 at Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital. MSCs were isolated and cultured from the bone marrow using the Ficoll separation method. Cell morphology was observed under high-resolution microscopy, and differences in the cytoskeletal features between AS-and HC-MSCs were analyzed through immunofluorescence staining. The expression of ICAM-1 was quantified in both groups using real-time quantitative polymerase chain reaction (RT-qPCR) and flow cytometry. Transwell migration assays and wound healing experiments were conducted to evaluate the differences in migration rates between the two groups of MSCs. Results: The interspinous ligament and bone marrow was acquired in AS (2 males and 1 female; 33, 37, 32 years old, respectively) and no-AS patients (2 males and 1 female; 35, 32, 38 years old, respectively). AS-MSCs exhibited broader cell morphology compared to HC-MSCs under bright field and fluorescence microscopy. Immunofluorescence staining of the interspinous ligament showed higher expression of ICAM-1 (68.38±3.42 vs 48.31±2.43) and CD105 (37.97±2.16 vs 23.36±2.06) in AS patients (both P<0.001). Western blot and RT-qPCR analysis revealed significantly stronger protein expression and transcription levels of ICAM-1 in AS-MSCs when compared to those in HC-MSCs (both P<0.001). Flow cytometry confirmed greater mean fluorescence intensity of ICAM-1 in AS-MSCs than in that in HC-MSCs (924.30±54.99 vs 636.47±40.03, P=0.002). Regarding cell adhesion efficiency, it showed no significant difference between AS-MSCs and HC-MSCs in the early stage of adhesion (0.5 h: 1 496±213 vs 1 205±163, P=0.133), but they were all significantly higher in AS-MSCs in the later stage (1 h: 2 894±172 vs 1 908±155, P=0.002; 2 h: 4 540±286 vs 3 334±188, P=0.004; 3 h: 5 212±281 vs 4 208±303, P=0.014). Finally, cell migration experiments demonstrated a stronger migration capability of AS-MSCs compared to HC-MSCs (5 449±172 vs 4 016±155, P<0.001), and the inhibition efficiency of A-205804 on the migration rate of AS-MSCs was stronger than that on HC-MSCs (2 145±239 vs 3 539±316, P=0.004). Conclusions: The aberrant expression of ICAM-1 markedly influences the adhesion and migration dynamics of MSCs. Elevated ICAM-1 levels in MSCs derives from patients with AS significantly enhance their migratory capabilities.

Web Site Accessibility Among Doctor of Physical Therapy Programs in the United States.

Given the impetus to improve accessibility for diverse learners seeking physical therapist education, it is critical that all entry points to access information have minimal barriers. This study identified Web site accessibility barriers among Doctor of Physical Therapy (DPT) programs in the United States. Web site accessibility has been evaluated among many institutions of higher education, but none focused on DPT education. Individuals with disabilities may be adversely affected by Web site accessibility barriers. This cross-sectional study included 262 DPT programs in the United States. Doctor of Physical Therapy program characteristics collected were geographic region, institutional control type (public/private), medical school affiliation, accreditation status, total institutional enrollment, and DPT class size. The Web Accessibility Evaluation (WAVE) Tool assessed data related to accessibility barriers among DPT program homepage Uniform Resource Locators. Three primary outcomes from the WAVE Tool included WAVE Total Errors, Error Density, and Total Alerts. Web site homepage accessibility barriers varied among programs for WAVE Total Errors (range 0-150), Error Density (range 0-14.6%), and Total Alerts (range 1-331). Median Total Errors were greater among private (9.0) versus public (5.0) institution Web sites (P < .001). Median Total Errors were greater among those institutions not affiliated with a medical school (9.0) compared with those that had an affiliated medical school (7.0) (P = .04). No differences in accessibility barriers were identified according to geographic region or accreditation status (P > .05). Median Total Errors were significantly different between institutional enrollment quartiles (H[3] = 17.9, P < .001), with no differences noted between DPT class size quartiles for any outcome (P > .05). Generally, weak-fair inverse correlations were observed between student enrollment for the institution and Web site accessibility barrier outcomes. Homepage accessibility barriers varied greatly among DPT programs in the United States. Factors, including being a private institution, no medical school affiliation, and lower institutional enrollment, were related to increased accessibility barriers.

U.S. Medical School Participation in Nationally Funded Biomedical Research: A New Accounting of NIH Award Dollars.

To better understand the amount of National Institutes of Health (NIH) funding received by U.S. medical schools with Liaison Committee on Medical Education-accredited medical education programs, the Association of American Medical Colleges (AAMC) developed a new methodology that crosswalks faculty NIH grants with medical schools and their affiliated organizations (e.g., teaching hospitals). This approach offers a more comprehensive and methodologically transparent accounting of NIH extramural funding to academic medicine than existing processes.The AAMC Crosswalk utilized publicly available grants data from the NIH and resources unique to the AAMC, such as the Faculty Roster and Council of Teaching Hospitals and Health Systems records. Using a multi-step algorithm, the AAMC Crosswalk linked individual faculty with NIH grants, their organizations, and partner medical schools, aggregated at the level of the medical school and its affiliated organizations for fiscal year (FY) 2017-2021.The AAMC Crosswalk attributed on average $3.7 billion more per year in NIH funding to U.S. medical schools, representing a 24% increase compared to the NIH and Blue Ridge Institute for Medical Research (BRIMR) methodologies. In FY 2021, the AAMC Crosswalk attributed 60% of NIH funding to U.S. medical schools compared with 47% by NIH and 50% by BRIMR. An exploration of limitations showed no medical school affiliations were missed by the AAMC Crosswalk among 90 randomly sampled organizations, and medical school affiliations for 30 randomly sampled principal investigator faculty members were attributed correctly.These findings indicate that academic medicine's contribution to biomedical research may be greater than historically reported. Systematically accounting for grants awarded to faculty across medical schools and their affiliated organizations provides a more comprehensive understanding of NIH funding to U.S. medical schools. The AAMC Crosswalk provides a new tool to better estimate the true investment and role of academic medicine in advancing biomedical research.

Geographic Proximity of Medical Students to PM&R Residency Programs Is Associated With Increased Match Rates Into PM&R.

Despite the growing popularity of physical medicine and rehabilitation as a specialty among medical students, meaningful experiences and mentorship can be challenging to obtain and may significantly vary depending on opportunities available to interact with physiatrists. This study explores the association between the geographic proximity of physical medicine and rehabilitation residency programs to medical schools and the match rate of medical students into physical medicine and rehabilitation from 2019 to 2021. Data on US medical schools, graduates, and physical medicine and rehabilitation residency programs were collected from publicly available sources, and a sample of 1193 physical medicine and rehabilitation residents from US medical schools was analyzed using a one-sample proportion test. The proportion of physical medicine and rehabilitation residents originating from medical schools with physical medicine and rehabilitation residency programs in the same metropolitan area was significantly greater than the corresponding proportion of expected residents based on medical school graduates, even when controlling for medical school affiliations with physical medicine and rehabilitation residency programs. These findings suggest that exposure and opportunities provided by physical medicine and rehabilitation residency programs may influence nearby medical students and that expanding residency programs into geographic regions without existing physical medicine and rehabilitation programs may foster interest and promote growth in the field of physiatry.

Appendicitis Hospitalization Care Costs Among Patients With Delayed Diagnosis of Appendicitis

Delayed appendicitis diagnosis is associated with worse outcomes. Appendicitis hospital care costs associated with delayed diagnosis are unknown. To determine whether delayed appendicitis diagnosis was associated with increased appendicitis hospital care costs. This cohort study used data from patients receiving an appendectomy aged 18 to 64 years in 5 states (Florida, Maryland, Massachusetts, New York, Wisconsin) that were captured in the Healthcare Cost and Utilization Project State Inpatient and Emergency Department databases for the years 2016 and 2017 with no additional follow-up. Data were analyzed January through April 2023. Delayed diagnosis was defined as a previous emergency department or inpatient hospital encounter with an abdominal diagnosis other than appendicitis, and no intervention 7 days prior to appendectomy encounter. The main outcome was appendicitis hospital care costs. This was calculated from aggregated charges of encounters 7 days prior to appendectomy, the appendectomy encounter, and 30 days postoperatively. Cost-to-charge ratios were applied to charges to obtain costs, which were then adjusted for wage index, inflation to 2022 US dollar, and with extreme outliers winsorized. A multivariable Poisson regression estimated appendicitis hospital care costs associated with a delayed diagnosis while controlling for age, sex, race and ethnicity, insurance status, care discontinuity, income quartile, hospital size, teaching status, medical school affiliation, percentage of Black and Hispanic patient discharges, core-based statistical area, and state. There were 76 183 patients (38 939 female [51.1%]; 2192 Asian or Pacific Islander [2.9%], 14 132 Hispanic [18.5%], 8195 non-Hispanic Black [10.8%], 46 949 non-Hispanic White [61.6%]) underwent appendectomy, and 2045 (2.7%) had a delayed diagnosis. Delayed diagnosis patients had median (IQR) unadjusted cost of $11 099 ($6752-$17 740) compared with $9177 ($5575-$14 481) for nondelayed (P < .001). Patients with delayed diagnosis had 1.23 times (95% CI, 1.16-1.28 times) adjusted increased appendicitis hospital care costs. The mean marginal cost of delayed diagnosis was $2712 (95% CI, $2083-$3342). Even controlling for delayed diagnosis, non-Hispanic Black patients had 1.22 times (95% CI, 1.17-1.28 times) the adjusted increased appendicitis hospital care costs compared with non-Hispanic White patients. In this cohort study, delayed diagnosis of appendicitis was associated with increased hospital care costs.

The Impact of a New Anesthesiology Residency Program on the Number of Medical Students Matching Into Anesthesiology at a Single Institution: A Retrospective Longitudinal Study.

Introduction There are projected workforce shortages within anesthesiology exacerbated by an increase in demand for anesthesia services and an aging anesthesia workforce. Given this mismatch, it is critical for the specialty to recruit the next generation of anesthesiologists and understand the factors affecting medical students' decision to apply to anesthesiology. This study aims to evaluate the impact of establishing a new anesthesiology residency program at a single institution on the number of medical students that match into anesthesiology in the subsequent years. Methods A single-center, retrospective longitudinal study examined the number of medical students matching into anesthesiology at a single institution between 2013 and 2023, five years before and after the establishment of an accredited anesthesiology residency program. The data were compared to aggregated data on all US medical student applicants through the National Resident Matching Program. Results The pre-anesthesiology residency match rate (2013-2018) of medical students from Alpert Medical School (AMS) was 2.47% while the post-anesthesiology residency match rate (2019-2023) was 4.30%. This represents a 74% increase in the average proportion of medical students matching into anesthesiology after the start of the residency program compared to a 20% increase nationally over the same time period. The rate of change of AMS matched applicants after the implementation of the AMS anesthesia residency program increased compared to the national applicant pool (p= 0.002). Conclusion The establishment of a new accredited anesthesiology residency program increased the proportion of medical students matching into anesthesiology at the affiliated medical school in the subsequent five years. Exposure to an academic anesthesiology program improves medical student interest and ultimately matches rates in anesthesiology, a vital tool to address the projected shortages in the anesthesiology workforce.

A decade of diversity: using statistical indices to compare neurosurgery to other surgical specialties

OBJECTIVE Studies have demonstrated the benefits of diversity in neurosurgery. However, recruitment of minoritized groups within the neurosurgical workforce consistently lags other surgical specialties. While racial and gender demographics of neurosurgical residents are well documented, there has been minimal exploration into the multidimensional nature of diversity. The current study will evaluate the longitudinal diversity changes in neurosurgery residency programs compared with other surgical fields with validated diversity indices. METHODS Nationwide reports including data about resident physicians were obtained from the American Medical Association and the Association of American Medical Colleges for the academic years 2008–2021. Self-reported race, biological sex, and medical school affiliation were recorded for surgical residents in the 10 commonly recognized surgical fields. The Gini-Simpson Diversity Index was used to calculate the effective counts (ECs) of races, sexes, and medical school types for each field. A Composite Diversity Index (CDI) comprising the aforementioned diversity traits was used to calculate the percentage of characteristics upon which two randomly selected residents within each specialty would differ. CDIs were calculated for each field in every year from 2008 to 2021. Median CDIs were compared between fields using Kruskal-Wallis testing, and p values &lt; 0.05 were deemed statistically significant. RESULTS Plastic surgery had the highest median sex EC (1.92, interquartile range [IQR] 1.78–1.95), indicating greater diversity, while neurosurgery had the third lowest sex EC (1.40, IQR 1.35–1.41). All surgical fields examined had fewer than 3 races effectively represented among their residents, despite there being 8 races present. Neurosurgery ranked among the top fields in effective racial diversity (EC 2.17, IQR 2.09–2.21) and medical school type diversity (EC 1.25, IQR 1.21–1.26). There were statistically significant differences in the sex, race, and school ECs between surgical specialties. While neurosurgery had a relatively low median overall diversity (CDI = 32.7, IQR 32.0–34.6), there was a consistent longitudinal increase in CDI from 2015 to 2021. CONCLUSIONS Neurosurgery resident physicians have become increasingly diverse in the past decade but are more homogenous than residents in other surgical fields. The continued use of diversity indices to more accurately track diversity progress over time may better inform leaders in the field of how they may best focus their equity and inclusion efforts.

Diversity and Inclusion Analysis of the Association of Program Directors in Surgery's Annual Conference From 2010 to 2022

Explored the diversity and inclusion of our annual meeting. The authors compared our members' diversity to the participation in the impactful portions of our annual conference as a measure of our organizational inclusion. The authors retrospectively reviewed and calculated the diversity demographics of our membership based on our 2022 data. Demographics consisted of institutional affiliation and gender. Also the authors retrospectively analyzed the topics discussed at our annual meeting from 2010 to 2022. In 2022, the Association of Program Directors in Surgery (APDS) had 308 members; while we had 100% of the institutional affiliation, most members did not self-report gender or ethnicity information. One hundred eleven members self-reported gender information in 2022: 76% were men and 24% were women. Fifty-seven percent of our institutions had a medical school affiliation, 40% had a nonmedical school affiliation, and 3% had a military instillation affiliation. The authors' current analysis demonstrates disparities in the distribution of meaningful space in the APDS meeting program. Future efforts are ongoing to identify members and their demographics, track participation, and encourage more diverse involvement across membership.

Variation in academic neurosurgery departments’ #neurosurgery social media influence

BackgroundSocial media use is increasingly common among academic neurosurgery departments, but its relationship with academic metrics remains underexamined. MethodsWe examine the relationship between American academic neurosurgery departments’ number of followers on Twitter, Instagram, and Facebook and the following academic metrics: Doximity Residency rankings, US News & World Report rankings (USNWR) of their affiliated medical schools, and the amount of NIH funding of those schools. ResultsFew departments had disproportionate number of followers. A greater proportion of programs had Twitter accounts (88.9%) than had Instagram (72.2%) or Facebook (51.9%) accounts (p=0.0001). Programs identified as "Influencers" had more departmental NIH funding (p=0.044), more institutional NIH funding (p=0.035), better Doximity residency rankings (p=0.044), and better affiliated medical school rankings (p=0.002). Number of Twitter followers had the strongest correlation with academic metrics, yet only modest correlations were identified to departmental NIH funding (R=0.496, p=0.0001), institutional NIH funding (R=0.387, p=0.0072), Doximity residency rank (R=0.411, p=0.0020), and affiliated medical school ranking (R=0.545,p<0.0001). On multivariable regression, only being affiliated with a medical school in the top quartile on the USNWR rankings, rather than neurosurgery departmental metrics, predicted having more Twitter (OR=5.666, p=0.012) and Instagram (OR=8.33, p=0.009) followers. ConclusionAmerican academic neurosurgery departments preferentially use Twitter over Instagram or Facebook. Their Twitter or Instagram presences are associated with better performance on traditional academic metrics. However, these associations are modest, suggesting that other factors contribute to a department’s social media influence. A department’s affiliated medical school may contribute to the department’s social media brand.

Recruitment into Academic Neurosurgery Using a Model for Successful Cross-Campus Research Collaboration: A Premedical Student Survey

Recruitment of diverse and talented students to the field of neurosurgery is key to its continued growth and scientific advancement. Barriers, including poor perceptions and lack of early exposure, can impact recruitment and have been compounded by the ongoing COVID-19 pandemic. This study examines the impact of an inaugural Neurosurgery Research Consortium meeting on premedical students, assessing whether this exposure generated interest and improved perceptions of a career in neurosurgery. Premedical students were recruited to virtually attend an inaugural Neurosurgery Research Consortium developed by the affiliated medical school's American Association of Neurological Surgeons (AANS) Student Chapter. Questionnaires were distributed to students before and after the meeting to assess student demographics and perceptions of neurosurgery. A total of 54 students attended the meeting, with general interest in neurosurgery, medicine, and research opportunities being the primary factors for attendance. Following the research meeting, we found that students perceived neurosurgeons to be friendlier and more approachable, with a more positive quality of life (QoL). Overall perceptions of neurosurgery improved after the meeting, but perceptions among racial and ethnic minority students did not significantly change in the areas of diversity, inclusion, and equity. These results suggest recruitment strategies targeting undergraduate students may improve their perception of neurosurgery as a career, and may mitigate some barriers to entry. These strategies are cost effective and easily replicable, making an easily implementable approach to provide direct insight into neurosurgery for future medical students while also promoting academic efforts in the field of neurosurgery.

Over-Application and Interviewing in the 2021 United States Primary Care Virtual Recruitment Season.

Importance Over-application and interviewing are believed to be widespread in residency recruitment. These may have increased during the 2021 virtual recruitment season. The increase does not correspond to an increase in available residency positions and likely results in more interviews with low probabilities of yielding matches. Prior work demonstrates that such marginal interviews are identifiable ‑ from key explanatory factors like same-state for interviewee and program ‑ in sufficient volume to allow programs to substantially decrease interviews. Objective To evaluate the importance of same-state relationships in primary care and to determine the extent of over-interviewing in the 2021 virtual recruitment season. Design The National Resident Matching Program and Thalamus merged match (outcomes) and interview (explanatory variables) data from primary care specialties (family medicine, internal medicine, pediatrics). Data were analyzed by logistic regression, trained on the 2017-2020 seasons, and projected on the 2021 season for testing. Setting The setting was the 2017-2021 main residency matches. Participants This comprised 4,442 interviewees applying to 167 residency programs in primary care. Intervention This included the transition to virtual recruitment from in-person recruitment in the 2021 residency recruitment season. Measurements A total of 20,415 interviews and 20,791 preferred programs with program and interviewee characteristics and match outcomes were included. Results Same-state geographic relations predicted match probability in primary care residency interviews better than medical school/residency affiliation, with 86.0% of interviewees matching consistently with their preferences for the same state. Same-state was more effective than medical school affiliations with programs in predicting matching. Eliminating interviews with less than a 5% probability of matching (upper 95% prediction limit) removed 31.5% of interviews. Conclusions and relevance The large number of low-match probability interviews demonstrates over-interviewing in primary care. We suggest that programs eliminate interview offers to applications falling below their chosen match probability threshold.

Using a Multidimensional Statistical Approach to Evaluate Diversity Trends Among U.S. Neurology Residents Between 2008–2020 (S13.001)

<h3>Objective:</h3> To develop a multidimensional statistical model to quantify diversity within neurology residency. <h3>Background:</h3> Studies have demonstrated the benefits of diversity in medicine. However, recruitment and retention within neurology consistently lags behind other medical specialties. While demographics of neurology graduates has been studied, no statistical models exist to objectively assess diversity among graduates entering into the neurological workforce. <h3>Design/Methods:</h3> Demographics of neurology residents between 2008–2020 across 3 categories (sex, medical school affiliation, race/ethnicity) was measured. Within each category, <i>μ</i> (the probability that two randomly individuals represent a different sex, medical school affiliation [US MD, DO, IMG, or Canadian], or race/ethnicity), and true diversity, <i>D</i> (the effective number of equally populated categories per variable), were calculated. All 3 categories were combined using the Sullivan composite diversity index (CDI) to produce <i>A</i>_<i>w</i> (the proportion of attributes on which two random residents will differ). Linear regressions of <i>D</i> for each variable across time was calculated. <h3>Results:</h3> There were an average of 2,326 residents/year, with 36% female, 95% US MD graduate, and 70% White. The probability that two random residents represented a different: sex was 49.6%; medical school affiliation was 56.4%; and racial/ethnic group was 60.9%. This corresponded to an effective number of 1.98 sexes, 2.29 medical school types, and 2.56 races/ethnicities. True diversity <i>D</i> increased over time for medical school affiliation only (+0.016/year), while <i>D</i> remained constant for sex and race/ethnicity. Lastly, two random residents differed on about 55.6% of all attributes (<i>A</i>_<i>w</i>), suggesting relative heterogeneity. <h3>Conclusions:</h3> Both sexes are nearly equally represented across neurology residents, and neurology residency programs were represented by effectively two different medical school affiliations. However, despite the presence of seven races in the population, neurology residents were only as diverse as a cohort with 2.5 equally represented races. Leaders in neurology should consider additional strategies to improve the neurology residency recruitment. <b>Disclosure:</b> Mr. Persad-Paisley has received research support from NIH National Heart, Lung, Blood Institute (NHLBI) . Ms. Paracha has nothing to disclose. Ms. Moges has nothing to disclose. Dr. Daruvala has nothing to disclose. Dr. Mahta has nothing to disclose. The institution of Dr. Ayub has received research support from Brown Physicians Incorporated.

Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis.

Conflicting evidence exists regarding the risks and benefits of inotropic therapies during cardiac surgery, and the extent of variation in clinical practice remains understudied. Therefore, the authors sought to quantify patient-, anesthesiologist-, and hospital-related contributions to variation in inotrope use. In this observational study, nonemergent adult cardiac surgeries using cardiopulmonary bypass were reviewed across a multicenter cohort of academic and community hospitals from 2014 to 2019. Patients who were moribund, receiving mechanical circulatory support, or receiving preoperative or home inotropes were excluded. The primary outcome was an inotrope infusion (epinephrine, dobutamine, milrinone, dopamine) administered for greater than 60 consecutive min intraoperatively or ongoing upon transport from the operating room. Institution-, clinician-, and patient-level variance components were studied. Among 51,085 cases across 611 attending anesthesiologists and 29 hospitals, 27,033 (52.9%) cases received at least one intraoperative inotrope, including 21,796 (42.7%) epinephrine, 6,360 (12.4%) milrinone, 2,000 (3.9%) dobutamine, and 602 (1.2%) dopamine (non-mutually exclusive). Variation in inotrope use was 22.6% attributable to the institution, 6.8% attributable to the primary attending anesthesiologist, and 70.6% attributable to the patient. The adjusted median odds ratio for the same patient receiving inotropes was 1.73 between 2 randomly selected clinicians and 3.55 between 2 randomly selected institutions. Factors most strongly associated with increased likelihood of inotrope use were institutional medical school affiliation (adjusted odds ratio, 6.2; 95% CI, 1.39 to 27.8), heart failure (adjusted odds ratio, 2.60; 95% CI, 2.46 to 2.76), pulmonary circulation disorder (adjusted odds ratio, 1.72; 95% CI, 1.58 to 1.87), loop diuretic home medication (adjusted odds ratio, 1.55; 95% CI, 1.42 to 1.69), Black race (adjusted odds ratio, 1.49; 95% CI, 1.32 to 1.68), and digoxin home medication (adjusted odds ratio, 1.48; 95% CI, 1.18 to 1.86). Variation in inotrope use during cardiac surgery is attributable to the institution and to the clinician, in addition to the patient. Variation across institutions and clinicians suggests a need for future quantitative and qualitative research to understand variation in inotrope use affecting outcomes and develop evidence-based, patient-centered inotrope therapies.

PD30-09 TRENDS IN FEMALE AUTHORSHIP AMONG UROLOGY RESIDENTS: IS THE GENDER GAP CLOSING?

You have accessJournal of UrologyCME1 Apr 2023PD30-09 TRENDS IN FEMALE AUTHORSHIP AMONG UROLOGY RESIDENTS: IS THE GENDER GAP CLOSING? Melody Ong, Joshua Ballway, Emily Kokush, John Fastenau, George Mina, Madeleine Andreas, Rose Maisner, Mohit Khera, and Hossein Sadeghi-Nejad Melody OngMelody Ong More articles by this author , Joshua BallwayJoshua Ballway More articles by this author , Emily KokushEmily Kokush More articles by this author , John FastenauJohn Fastenau More articles by this author , George MinaGeorge Mina More articles by this author , Madeleine AndreasMadeleine Andreas More articles by this author , Rose MaisnerRose Maisner More articles by this author , Mohit KheraMohit Khera More articles by this author , and Hossein Sadeghi-NejadHossein Sadeghi-Nejad More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003316.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Gender disparities have been demonstrated among women in academia. Women face barriers to acquiring mentorship, publishing, and obtaining academic promotions. Urology, a historically male-dominated field, has seen a steady rise in female representation in recent years. With the proportion of females matching to urology increasing each year, this study aims to examine the current trends in academic productivity of urology residents based on gender. METHODS: Urology residents in the top 50 Doximity reputation ranking residency programs in 2021-2022 were identified through program websites and Twitter accounts. Publications during residency were recorded from July 1 of PGY1 year to December 2021 using PubMed and Scopus. Demographic data including training year, geographic location, program size, program length, and medical school affiliation were collected. Research productivity was measured by number and type of publications, authorship position, H-index, and journal impact factor. Chi-square and Mann-Whitney U tests were used to perform statistical analyses. RESULTS: 801 residents from 46 urology programs were identified. Females accounted for 31% of the residents, while 69% were males. There were no significant differences in distribution between female and male residents for year of training, program geographic region, average number of residents per year, program length, program with mandatory research year, resident graduation from a top 50 research medical school, and program affiliation with a top 20 research medical school. Overall, the median (interquartile range) number of publications was higher in male than female residents [2(0-5) vs. 1(0-3), p=0.001]. Similarly, the h-index for males was higher overall [2(1-4), vs. 1(1-3), p=0.002]. However, when residents were stratified by year of training, the total number of publications and h-indices were not significantly different between genders, with the exception of male residents having a higher h-index in their PGY2 year [2(1-4) vs. 1(0-2), p=0.014]. The percentage of first or second author publications for each resident, as well as the percentage of original articles and articles published in a high-impact urology journal, did not differ between genders. CONCLUSIONS: At first glance, male urology residents seem to produce more research than female residents. However, after stratification by year of training, research productivity is similar between genders. These promising results suggest that the gender gap for women in academia may be closing as female representation continues to improve in urology. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e834 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Melody Ong More articles by this author Joshua Ballway More articles by this author Emily Kokush More articles by this author John Fastenau More articles by this author George Mina More articles by this author Madeleine Andreas More articles by this author Rose Maisner More articles by this author Mohit Khera More articles by this author Hossein Sadeghi-Nejad More articles by this author Expand All Advertisement PDF downloadLoading ...

Widespread Third-Party Tracking On Hospital Websites Poses Privacy Risks For Patients And Legal Liability For Hospitals.

Computer code that transfers data to third parties (third-party tracking) is common across the web and is subject to few federal privacy regulations. We determined the presence of potentially privacy-compromising data transfers to third parties on a census of US nonfederal acute care hospital websites, and we used descriptive statistics and regression analyses to determine the hospital characteristics associated with a greater number of third-party data transfers. We found that third-party tracking is present on 98.6percent of hospital websites, including transfers to large technology companies, social media companies, advertising firms, and data brokers. Hospitals in health systems, hospitals with a medical school affiliation, and hospitals serving more urban patient populations all exposed visitors to higher levels of tracking in adjusted analyses. By including third-party tracking code on their websites, hospitals are facilitating the profiling of their patients by third parties. These practices can lead to dignitary harms, which occur when third parties gain access to sensitive health information that a person would not wish to share. These practices may also lead to increased health-related advertising that targets patients, as well as to legal liability for hospitals.

Adjuvant treatment of surgically treated bone metastasis patients: association with hospital characteristics and trends over time.

Patients with metastatic disease of the bone (MDB) often require surgical stabilization; however, there is not widespread consensus on subsequent adjuvant management. This study aimed to characterize utilization of perioperative adjuvant treatment among MDB patients. We identified 9413 surgically treated MDB patients with primary (breast, kidney, lung, prostate, or multiple myeloma) cancer from Surveillance, Epidemiology, and End Results (SEER)-Medicare data. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for receipt of chemotherapy, radiation, and bisphosphonates, respectively, in the adjuvant setting (90days before or after surgery) by hospital characteristics-medical school affiliation, surgery volume, and Commission on Cancer (CoC) accreditation. Trends in treatment utilization by year of surgery were assessed via bar charts and Chi-square tests for trend. Patients surgically treated at major medical schools or high-volume facilities (compared to no medical school affiliation and low volume) had significantly higher odds of receiving radiation and chemotherapy, independent of patient and tumor characteristics (OR (95% CI); medical school: radiation 1.33 (1.19-1.49), chemotherapy 1.15 (1.02-1.30); and high volume: radiation 1.22 (1.11-1.34), chemotherapy 1.11 (1.02-1.22)). Patients surgically treated at CoC-accredited institutions, compared to non-accredited, had significantly higher odds of receiving radiation and bisphosphonates [radiation 1.24 (1.13-1.36); bisphosphonates 1.15 (1.04-1.28)]. Use of chemotherapy and bisphosphonates increased while radiation use declined over the study period from 1991 to 2014. Medical school affiliation, hospital volume, and CoC accreditation are associated with receipt of adjuvant treatment to prevent or manage pathologic fractures in MDB patients. Further investigation is needed to determine whether these associations reflect delivery of optimal care.

The Demographic Make-up of Orthopaedic Surgery Residents in the United States Post ACGME Merger

Objective The purpose of this study was to investigate differences in the demographic characteristics of orthopaedic surgery residents in 2021 in regard to sex, degree earned, and regional or medical school affiliation. Design The Fellowship and Residency Electronic Interactive Database was used to identify all orthopaedic surgery residency programs in the United States. Resident sex, degree, residency year, and geographic region attended for residency and medical school were collected from each program website. Results 199 orthopaedic surgery residencies were identified: 153 traditional Accreditation Council for Graduate Medical Education (tACGME) programs, 38 traditional American Osteopathic Association (tAOA) programs, and 8 military programs, which were excluded. 4,095 orthopaedic surgery residents were identified. Females accounted for 16.6% (N=679) of residents, 17.6% (N=620) within tACGME programs and 10.4% (N=59) in tAOA programs (p&lt;0.001). The 573 orthopaedic residents with DO degrees accounted for 14% of the residents identified, 97.6% (N=533) of residents in tAOA programs, and 1.1% (N=40) of residents in tACGME programs. Regional data showed that 34.4% (N=1208) of MDs trained in the Northeast, while 41.9% (N=240) of DOs trained in the Midwest. Conclusion There has been a slight increase in the representation of females and DOs in orthopaedic surgery residency programs since the mid-2000s; however, data following the ACGME and AOA merger still shows significant predilection for male and MD degree applicants. This study suggests that the Northeast and Midwest regions of the United States train more MDs and DOs, respectively. This finding offers potential data for interested applicants and demonstrates opportunity for more heterogeneity in applicant selection.

Vaccine Hesitancy among Medical Students at a Tertiary Hospital—Affiliated Medical School

The coronavirus disease 2019 (COVID-19) caused a global pandemic with long-lasting economic and cultural impacts. International governments have attempted to scale up vaccine production to mitigate this crisis. However, vaccine hesitancy, particularly among healthcare providers, remains an understudied subject that may hinder vaccine effectiveness. We performed a cross-sectional study to evaluate vaccine hesitancy among medical students using a pre-validated survey based on the 5C model of psychological antecedents, which includes confidence, complacency, constraints, calculation, and collective responsibility. The majority of medical students had high scores for confidence (79.7%), non-complacency (88%), and not having constraints against receiving the COVID-19 vaccine (97.4%). Surprisingly, students had low scores for calculation (38%) and collective responsibility (14.7%). Many predictors of the psychological antecedents included in the 5C model have been reported, including academic year and gender. We observed moderate levels of vaccine hesitancy among the medical students included in our study. We urge medical students to be more aware of community public health concerns. We recommend that authorized institutions lay out urgent reforms to increase awareness of COVID-19 and available vaccines.

A Gap in Mission: The Disparate Missions of Medical Schools and Teaching Hospitals

Objective The social contract mandates that in return for the government-funded labor of residents and fellows, the medical profession trains, to the best of its ability, the physicians of our future. This contract obligates graduate medical education (GME) to utilize all available information to create an optimal learning environment for its trainees. Business research has determined that a clearly defined mission statement is associated with improved employee engagement, retention, and wellness. Given that GME trainees are situated at the intersection of at least two institutions, each with its own separate mission, trainees could potentially be hindered by incongruent missions in the learning environment. The literature on mission statements has analyzed medical schools and hospitals separately; however, investigations comparing the statements of these affiliated institutions have not been conducted. Therefore, we plan to compare the content and assess the consistency of mission statements from affiliated medical schools and hospitals to determine if incongruencies exist. Methods In 2023, the mission statements from the Association of American Medical Colleges (AAMC) medical schools and affiliated teaching hospitals (n = 163) were aggregated from their public websites. The content of each mission statement was thematically analyzed to assess variation. Results According to content analysis of the mission statements from 163 AAMC medical school members and affiliated teaching hospitals, less than half of their top priorities are shared by their affiliated hospitals (45%). Additionally, themes of diversity, religion, and global care were found to be contrasting priorities between affiliated institutions. Conclusion Given the precedence within the business and the observed discrepancies in mission, further research is needed to determine whether collaborating medical schools and hospitals could provide a more favorable graduate training environment by uniting their priorities and identifying shared goals.

Diversity in Orthopaedic Surgery Residencies Based on Allopathic Medical School Affiliation.

All 202 Accreditation Council for Graduate Medical Education (ACGME)-accredited orthopaedics programs were divided into 2 groups: Group 1 consisted of residency programs without an affiliated allopathic medical school, and Group 2 consisted of programs with an affiliated allopathic medical school. Affiliations were determined by cross-referencing the ACGME residency program list with the medical school list published by Association of American Medical Colleges (AAMC). Program and resident characteristics were then compiled using AAMC's Residency Explorer including region, program setting, number of residents, and osteopathic recognition. Resident characteristics included race, gender, experiences (work, volunteer, and research), peer-reviewed publications, and US Medical Licensing Examination Step 1 scores. Of the 202 ACGME-accredited orthopaedics residencies, Group 1 had 61 (30.2%) programs, and Group 2 had 141 (69.8%) programs. Group 2 had larger programs (4.9 vs. 3.2 resident positions/year; p < 0.001) and 1.7 times the number of residency applicants (655.8 vs. 385.5; p < 0.001). Most Group 2 residents were allopathic medical school graduates, 95.5%, compared with 41.6% in Group 1. Group 1 had 57.0% osteopathic medical school graduates, compared with 2.9% in Group 2. There were 6.1% more White residents in Group 1 residencies (p = 0.025), and Group 2 residencies consisted of 3.5% more Black residents in relation to Group 1 (p = 0.03). Academic performance metrics were comparable between the 2 groups (p > 0.05). This study demonstrated that candidates who successfully match into an orthopaedic surgery residency program achieve high academic performance, regardless of whether the program was affiliated with an allopathic medical school. Differences may be influenced by increased representation of minority faculty, greater demand for allopathic residents, or stronger emphasis on promotion of diversity in those residency programs. Available on reasonable request. Level III. See Instructions for Authors for a complete description of levels of evidence.