Medical Center Blvd Research Articles

Pediatric urology

Department of Urology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA Correspondence to Tony Atala, Department of Urology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA E-mail: [email protected]

Vacuum‐assisted closure for management of a traumatic neck wound in a horse

Equine Veterinary EducationVolume 17, Issue 1 p. 27-33 Vacuum-assisted closure for management of a traumatic neck wound in a horse K. D. Gemeinhardt, Corresponding Author K. D. Gemeinhardt Latitude 36 Mobile Veterinary Services, PO Box 466, Germanton, North Carolina, USALatitude 36 Mobile Veterinary Services, PO Box 466, Germanton, North Carolina, USASearch for more papers by this authorJ. A. Molnar, J. A. Molnar Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, North Carolina, USASearch for more papers by this author K. D. Gemeinhardt, Corresponding Author K. D. Gemeinhardt Latitude 36 Mobile Veterinary Services, PO Box 466, Germanton, North Carolina, USALatitude 36 Mobile Veterinary Services, PO Box 466, Germanton, North Carolina, USASearch for more papers by this authorJ. A. Molnar, J. A. Molnar Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, North Carolina, USASearch for more papers by this author First published: 05 January 2010 https://doi.org/10.1111/j.2042-3292.2005.tb00331.xCitations: 31AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume17, Issue1February 2005Pages 27-33 RelatedInformation

Parecoxib, Valdecoxib, and Cardiovascular Risk

Selective inhibitors of cyclooxygenase (COX)-21 depress prostacyclin (PGI2) but not COX-1–derived thromboxane A2. The effects of thromboxane A2 would be exaggerated during treatment with COX-2 inhibitors, potentially predisposing patients to heart attack and stroke.2 A randomized controlled trial in patients undergoing coronary artery bypass graft (CABG) surgery and receiving either placebo or 40 mg parecoxib (Dynastat; Pfizer), the intravenously administered prodrug of valdecoxib (Bextra; Pfizer), followed by oral valdecoxib 40 mg BID for 14 days, revealed a cluster of cardiovascular events.3 In a second study, one group received parecoxib/valdecoxib, another …

POOR NUTRITIONAL STATUS AND INFLAMMATION: Poor Nutritional Status and Inflammation: Mechanisms and Treatment

Seminars in DialysisVolume 17, Issue 6 p. 425-426 POOR NUTRITIONAL STATUS AND INFLAMMATION: Poor Nutritional Status and Inflammation: Mechanisms and Treatment Michael V. Rocco, Corresponding Author Michael V. Rocco Department of Internal Medicine, Division of Nephrology, Wake Forest University School of Medicine, Winston-Salem, North CarolinaAddress correspondence to: Michael V. Rocco, MD, MSCE, Department of Internal Medicine/Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1053, or e-mail: [email protected].Search for more papers by this author Michael V. Rocco, Corresponding Author Michael V. Rocco Department of Internal Medicine, Division of Nephrology, Wake Forest University School of Medicine, Winston-Salem, North CarolinaAddress correspondence to: Michael V. Rocco, MD, MSCE, Department of Internal Medicine/Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1053, or e-mail: [email protected].Search for more papers by this author First published: 09 December 2004 https://doi.org/10.1111/j.0894-0959.2004.17601.xRead the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Volume17, Issue6November 2004Pages 425-426 RelatedInformation

The Vomiting Infant

Dr. Anthony is Assistant Professor of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088; E-mail: [email protected]. The author has disclosed that she has no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

Abdominal Lymph Nodes

Dr. Bechtold is Professor of Radiology, and Dr. Chen is Associate Professor of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088; E-mail:[email protected]. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

Benign Conditions of the Colon: Part II

Dr. Chen is Associate Professor of Radiology, and Dr. Ott is Professor of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157; E-mail: [email protected]. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

The US smallpox vaccination plan.

The American Academy of Pediatrics (AAP) recently published a policy statement on the use of the smallpox vaccine in children.1 This commentary expands on issues raised by Congress2 regarding the implementation of a smallpox vaccination program in children. AAP policy states that children should not be offered the smallpox vaccine at this time. This recommendation is based on weighing the fact that infants and children are particularly vulnerable to serious complications caused by the smallpox vaccine, including death, versus the government’s own assessment that the current risk of a smallpox attack is low.3 When the risk of a smallpox attack is low, a ring-vaccination policy that includes a plan for rapid distribution … Address correspondence to Jon S. Abramson, MD, Department of Pediatrics, Wake Forest University School of Medicine, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157-0001. E-mail: jabrams{at}wfubmc.edu

Cystic fibrosis: bench to bedside 2003.

Department of Pediatrics, and Departments of Biomedical Engineering, Physiology and Pharmacology, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, North Carolina, USA Correspondence: Dr Bruce K Rubin, Department of Pediatrics, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1081, USA. Telephone 336-716-0512, fax 336-716-9229, e-mail brubin@wfubmc.edu In the 17 years since the cystic fibrosis transmembrane ion regulator (CFTR) gene and protein were first identified at the Hospital for Sick Children in Toronto, Ontario (1), much has been learned about the primary defect in cystic fibrosis (CF) and how this relates to some of the clinical manifestations of this disease. The CFTR protein regulates airway chloride transport, and is also a regulator of sodium and water transport across the epithelium (2). In addition, it appears to play a role in the regulation of protein assembly and degradation within the cell (3). The complex regulatory network attributed to CFTR has made it difficult to link abnormalities of the gene and protein to the chronic airway infection and inflammation that are hallmarks of this disease. Thus, although the ‘cure’ for CF remains tantalizingly out of reach, new knowledge of disease pathogenesis and CFTR function has led to the development of novel therapies that have promise in controlling the relentless progress of lung disease (4). We have also learned that mild CFTR mutations can lead to a number of disorders now referred to as nonclassical CF (5). Some of these patients have chronic sinusitis and a later onset of chronic airway infection (6). Because of preserved exocrine pancreatic function, some patients develop pancreatitis in early adulthood (7). Sweat chloride values, usually in the range of 60 to 90 mmol/L, often are normal (8). Men with specific, mild CFTR defects can have no lung disease or pancreatic malabsorption, but only infertility with agenesis of the vas deferens and obstructive azoospermia (9). Because preservation of even a small amount of CFTR function appears to ameliorate lung disease, strategies have been proposed to augment abnormal CFTR function and enhance ion transport (10). This manuscript reviews some of the recently developed therapies for managing infection and inflammation in the CF airway, as well as progress toward correcting the abnormal chloride transport associated with CFTR protein malfunction, gene activation and gene replacement therapy, and finally the role of lung transplantation in end-stage CF lung disease.

Lymphoma of the Stomach and Small Bowel

Dr. Ott is Professor of Radiology and Dr. Chen is Associate Professor of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157; E-mail: [email protected]. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

What Is Your Diagnosis?

From the Departments of Pathology and Dermatology, Wake Forest University, School of Medicine, Winston-Salem, North Carolina. Address correspondence and reprint requests to Omar P. Sangueza, M.D., Department of Pathology, Wake Forest University School of Medicine, The Bowman Gray Campus, Medical Center Boulevard, Winston-Salem, NC 27157-1072. E-mail: [email protected]

Bryant.

On Being a Doctor5 November 2002BryantRichard B. Weinberg, MDRichard B. Weinberg, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-9-200211050-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The most peculiar thing about being fired is that everybody stops talking to you.“It's time for a change,” they told me, and with that, my decade of service as a section head was over.My telephone stopped ringing. My e-mail slowed to a trickle. No one knocked at my door. When I walked down the hallway, those who had lobbied for my downfall slipped guiltily by, the politically prudent—lest the gossip be true—avoided me, and the rest mumbled embarrassed condolences and rushed on to attend to their own problems. So alone in my office, I stewed in a toxic ... Author, Article, and Disclosure InformationAffiliations: Corresponding Author: Richard B. Weinberg, MD, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157; e-mail, [email protected]edu. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 5 November 2002Volume 137, Issue 9Page: 770-771KeywordsComputersEpilepsyFoodInternetLibrariesResidencySaltsTechnicians ePublished: 5 November 2002 Issue Published: 5 November 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Save Our Skin

Jill S. Smith, RN, CWOCN, is a Certified Wound, Ostomy, and Continence Nurse at North Carolina Baptist Hospital, Winston-Salem, North Carolina. Reprint requests: Jill Smith, RN, CWOCN, Staff Development, North Carolina Baptist Hospital, Medical Center Blvd, Winston-Salem, NC 27157; e-mail: [email protected].

Obstetric Anesthesia Handbook .

Assistant Professor, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina. ldean@wfubmc.eduBy Sanjay Datta. Hanley & Belfus, Philadelphia, 2000. Pages: 401. Price: $37.00.THE third edition of Obstetric Anesthesia Handbook presents a concise and current review of obstetric anesthesia that is easy to read, from beginning to end, as well as a quick clinical reference. The fact that the text has only one author allows for very little redundancy, as is often found in books written by several authors. There are a reasonable number of graphs and tables to supplement the text, and appropriate clinical pearls are italicized in each section to highlight the important aspects of each area.Datta's handbook is outlined in a very readable fashion beginning with a chapter on maternal physiology during pregnancy, labor, and postpartum. The next three chapters focus on maternal and perinatal pharmacology, emphasizing local anesthetics and drug interactions during pregnancy. The chapter on local anesthetics is concise and clinically useful, particularly to training practitioners. Uteroplacental circulation with an emphasis on the implications of those pharmacologic agents that alter blood flow is addressed in chapter 5. Datta focuses on labor and delivery in the next six chapters, including a review of nonpharmacologic options as well as systemic agents for labor analgesia. Fetal monitoring and the long-term effects of a variety of analgesic techniques on neonates are included.State of the art options for regional anesthesia for labor are described in chapter 11, including a thorough summary of potential complications. An elementary review of the anatomy of the epidural space and the site of action of anesthetics is very clear to the novice provider. Advantages and disadvantages of spinal, epidural, and general anesthesia for cesarean section are outlined and their techniques clearly summarized in the subsequent chapter.Chapter 13 is devoted to high-risk pregnancy. The chapter begins with advise on managing regional and general anesthesia for high-risk conditions. This extensive section is subdivided to include descriptions of hemorrhage, pregnancy induced hypertension, diabetes, cardiac and respiratory disease, neurologic problems, malpresentation, prematurity, multiple gestation, and a variety of other miscellaneous disorders. This chapter discusses a broad array of obstetric conditions addressing the anesthetic implications and guidelines for their management. There is a particularly useful summary of antihypertensive therapies before general anesthesia for the preeclamptic patient. These ninety pages are a good introduction to the pertinent anesthetic issues surrounding high-risk pregnancy.Neonatal resuscitation is covered in chapter 14 very clearly, with current recommendations from the American Heart Association. Anesthetic management for postpartum tubal ligation, in vitro fertilization, and anesthesia for nonobstetric surgery in the parturient is summarized in the next three chapters. The handbook concludes with a discussion of morbidity and mortality and includes the Practice Guidelines from the American Society of Anesthesiologists (ASA) task force on obstetric anesthesia. Dr. Datta intends this new edition of his earlier work as a current and clinically useful resource for training anesthesia care providers providers as well as more experienced anesthesiologists and obstetriciangynecologists. I believe he has met these goals.

Genitourinary system

Comprehensive Cancer Center of Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. Correspondence to Frank M. Torti, MD, Comprehensive Cancer Center of Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC, USA; e-mail: [email protected]

Esophagogastric Region: Anatomy, Function, And Common Disorders

Dr. Chen is Associate Professor of Radiology and Dr. Ott is Professor of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

Presidential address of the American Orthopaedic Society for Sports Medicine. Get involved!

Before I begin, I would like to play a short line from a song. It is from a group that I am sure many of you have heard about but have not actually heard. The line is from a song called Truckin’ by the Grateful Dead. It captures perfectly my years of involvement with the American Orthopaedic Society for Sports Medicine. “Sometimes the lights are shining on me, other times I can barely see. Lately, it occurs to me: what a long strange trip it’s been.” It has, indeed, been a long and strange trip through my medical career. But before we get to that, I would first of all like to acknowledge and thank some of the people present who have been with me on this journey and are, in large part, responsible for my not getting lost along the way. First of all, my parents. My father passed away in 1998, but my mother has taken time from her busy schedule to be here, and I know that she is absolutely amazed and, I hope, proud to see me up here as President of the AOSSM. I know there were many times when I was a youngster that I am sure that my parents were both positive I was never going to survive, let alone accomplish anything. Mom, I just want to let you know that I appreciate the many things that you have done to support me through the years. My two sons, Doug and Mike, along with Doug’s fiance Cory, are here today also. They are great kids and I am proud of them and grateful for the many wonderful times that we have had together over the years. I have them to thank for reintroducing me to the Grateful Dead. I bet you guys never thought you would be hearing them today! Thanks to my wife, Kay. We have been married for almost 31 years, so we have been together for almost my entire military and medical career. She has certainly been the beacon of light that has guided me along the way, ensuring that I did not wander too far off the path, either with my career or in the pursuit of one of my many whims. I am also pleased that my brother and sister, Gil and Cathy, could be here today, along with Gil’s wife, Ginny, and Cathy’s two daughters, Shannon and Meagan. Finally, a special thanks to Irv and Camille. They have been invaluable to me, not only in this past year as President, but also in my many associations with the Society in years past. My talk today is about involvement. I am sure many of us ask how we, as members of our Society, can get the most out of this association. I would like to play a sound clip that will set the stage for what I am going to say. As * Presented at the 27th annual meeting of the AOSSM, Keystone, Colorado, June 29, 2001. † Address correspondence and reprint requests to Walton W. Curl, MD, Wake Forest University School of Medicine, Department of Orthopaedic Surgery, Medical Center Boulevard, Winston-Salem, NC 27157-1070. 0363-5465/101/2929-0684$02.00/0 THE AMERICAN JOURNAL OF SPORTS MEDICINE, Vol. 29, No. 6 © 2001 American Orthopaedic Society for Sports Medicine

Benign Bone-Forming Tumors

Dr. Chew is Professor and Section Head of Musculoskeletal Radiology, Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088. The author has disclosed that he has no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

The Breast Cancers We Miss

Dr. Freimanis is Associate Professor and Dr. Lesko is Assistant Professor, Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity.

Reducing costs through centralization and standardization of an i.v. admixture program

Journal Article Reducing costs through centralization and standardization of an i.v. admixture program Get access Richard D. Paoletti, Richard D. Paoletti Manager Pharmacy Services, Crozer-Chester Medical Center, and IV Admixture Supervisor, Crozer-Keystone Health System, Upland, PA Address reprint requests to Mr. Paoletti at the Pharmacy Department, Crozer-Keystone Health System, One Medical Center Boulevard, Upland, PA 19013 or to rich.paoletti@crozer.org. Search for other works by this author on: Oxford Academic Google Scholar Edward W. Casey, M.B.A. Edward W. Casey, M.B.A. Director Pharmacy Services, Crozer-Keystone Health System Search for other works by this author on: Oxford Academic Google Scholar American Journal of Health-System Pharmacy, Volume 57, Issue 12, 15 June 2000, Pages 1147–1149, https://doi.org/10.1093/ajhp/57.12.1147 Published: 15 June 2000