Medical Academy Research Articles

Determination of subdural hematoma volume: Comparative analysis of calculation methods

Background. Accurate calculation of the volume of subdural hematomas of traumatic, vascular, and other origins during diagnosis is complicated which leads to difficulties in selection of optimal tactics of neurosurgical treatment. Aim. To preform comparative analysis of accuracy of different methods of subdural hematoma volume calculations to increase the quality of evaluation of the results of radiological methods in selection of surgical tactics.Materials and methods. Data from preoperative computed tomography of 20 patients (15 men and 5 women between the ages of 20 and 60 years) with confirmed diagnosis of subdural hematoma who were examined and treated at the Neurosurgery Clinic of the Kirov Military Medical Academy were used. Four groups were formed based of the calculation method: two groups using formulas for volume of ellipsoid or convexo-concave lens (the shape most accurately representing the shape of subdural hematoma); electronic algorithm of volume calculation (Gamma MultiVox D2 software, Gammamed-Soft, Russia); control method (manual sectional calculation of areas of the formed structures with subsequent summation).Results. Deviations between the obtained values varied between +18 and -16 %. Deviations for calculations using ellipsoid volume formula were +46 and -19 %; using convexo-concave lens formula +38 and -35 %, respectively. Electronic calculation algorithm (Gamma MultiVox D2) showed the best accuracy compared to other methods including the control method.Conclusions. Comparative analysis of the accuracy of the studied methods of calculation of subdural hematoma volume showed that median results are statistically similar which allows for selection and use of these methods in accordance with the neurosurgeon's preferences.Study of the algorithm based on ellipsoid volume shows low specificity of this method, comparatively high deviations of the results from the true value with a trend toward overprediction.Calculation using volume of convexo-concave lens showed intermediate result if the shape of the hematoma corresponded to the ideal chape of a figure enclosed between two segments of a sphere. In cases where the shape did not correspond to the convexo-concave lens, both overprediction and underprediction of hematoma volume were observed.Calculations using the Gamma MultiVox D2 software showed the highest accuracy, lowest range of deviation from the control data, best versatility, independence from both the shape and location of the subdural hematoma, as well as selection of a section used in other algorithms for the measurements.It should be noted that accuracy of determination of subdural hematoma volume by the studied methods is directly proportional to time necessary for calculation.

47P Prognostic value of dynamic HER2 status conversion in patients with metastatic breast cancer: Retrospective study of the Clinic of Medical Oncology of Military Medical Academy, Sofia, Bulgaria

With the implementation of anti-HER2 therapies in clinical practice, the OS of patients with HER2(+) breast carcinoma significantly improves. The aim of this retrospective analysis is to asses the prognostic value of dynamic HER2 status conversion among the patients with metastatic disease, treated in our institution.

Ocena wpływu wczesnej rehabilitacji na poziom występowania zaburzeń i proces reinerwacji na przykładzie gałązek ruchowych nerwu twarzowego u pacjentów po urazach twarzowo-czaszkowych

Introduction. Lymphoedema of the skull's facial part is one of the main complications observed in a patient after surgical treatment of disorders of this area. Another noticeable and frequently reported complication by the patient is irregularities in facial expression muscles' work. A relationship between them and reducing edema performed in patients in the first days after surgery will reduce the noted disturbances in motor branches' function. Aim. To investigate the impact of early swelling reduction on the extent of nervous system disorders and its reinnervation rate. Materials and methods. Patients of the Maxillofacial Surgery Clinic of the University Clinical Hospital of the Military Medical Academy in Łódź were enrolled in the study. The study was conducted on 60 people who underwent maxillofacial surgery procedures from February to December 2019. Lymphatic drainage and dynamic taping were used to reduce patients' edema. Forty-five people were divided into three equal groups. Fifteen patients constituted the comparative group. The research tools were a survey created following the author's idea, linear measurements for measuring edema, and the Pietruski scale for assessing the state of reinnervation imaged by mimic muscle motility. On the first day after surgery, patients were examined four times, then on the third and seventh day after surgery, and finally four months after surgery. Results. The use of anti-edema therapy noticeably (from 2-5 points on the Pietruski scale) reduces the disturbances in facial expression muscles' function. The difference has been visible already on the third day after surgery. Regarding the patient's pain, the lack of manual lymphatic system development resulted in pain sensations remaining in each of the three tests performed. The occurrence of edema, pain level, and level of facial expression muscle disorders were similar between groups and made the following research objective in terms of observed relationships. Conclusions. The level of disturbances in the area of the mobility of expressive facial muscles (based on Pietruski scale) indicates that the implementation of anti edematous therapy, and thus the reduction of excess lymph, already in the first days after surgery provides a reduction of disorders of conduction of efferent impulses of motor fibers, appearing already in the first days after surgery. Increased drainage rate also accelerates the reinnervation process, shortens it by several weeks, and reduces pain symptoms.

The Patriarch of maxillofacial traumatology (on the 100th anniversary of Professor V.A. Malyshev, Colonel of Medical Service)

The prominent place in the cohort of famous Russian dentists of XX century belongs to the participant of Great Patriotic War 19411945, Doctor of Medicine, Professor, colonel of medical service Vasily Alekseevich Malyshev (19222006), whose 100-year anniversary is celebrated by Russian stomatological community in 2022.
 AIM: To present scientific, clinical, pedagogical and social activity of prominent maxillofacial surgeon Doctor of Medicine, Professor, colonel of medical service V.A. Malyshev, as well as his merits before the Motherland.
 To present the role of V.A. Malyshev in formation and development of the military stomatology, maxillofacial surgery and traumatology in Russia on the basis of analysis of the national literature, life and professional activity as well as scientific labors of the doctor of medical sciences, professor, colonel of the medical service.
 Scientific works of V.A. Malyshev are mainly devoted to the research of issues of clinic, diagnostics, treatment of fractures of the lower jaw and prevention of traumatism. Having become the master of maxillofacial traumatology, he has significantly improved the diagnostics of maxillofacial injuries and introduced in everyday clinical practice a great number of original methods and effective ways of treatment of the indicated pathology. His scientific and practical developments and suggestions regarding the treatment of patients with maxillofacial region injuries have been widely spread in our country, implemented in practice of many medical preventive institutions and included in many textbooks, manuals and teaching aids used in Russian higher educational institutions. His method of treatment of chronic fractures of mandibular articular process by means of its replantation with following osteosynthesis, which was developed in our country and abroad, gained recognition not only in our country but also abroad.
 V.A. Malyshev was one of the oldest military dentists of Russia, a brilliant teacher, an excellent scientist and clinician. His name was well known to the stomatological community of the USSR, and since 1991 in Russia and the former Soviet Union. His work for 50 years was connected with the department of maxillofacial surgery and dentistry of Military Medical Academy named after S.M. Kirov. In 19751988 V.A. Malyshev as an off-duty chief dentist did a lot to improve the organization and provision of dental care to the servicemen and sailors.

75 lat polskiej medycyny i farmacji we Wrocławiu. Wybrane elementy historii wrocławskich wyższych uczelni. Część pierwsza (1945–1949)

75 years of Polish medicine and pharmacy in Wrocław. Selected elements from the history of higher education in Wrocław. Part one (1945–1949) Professional training in medicine and pharmacy had begun in Wrocław by the fall of 1945. The Faculty of Medicine was created within the structure of Wrocław University and Wrocław University of Science and Technology. Two departments were established within it: the Pharmaceutical and Dentistry departments. In 1950, a specialized medical school was developed from the University, functioning briefly under the name of the Medical Academy (which was changed to the Academy of Medicine), already with an independent Faculty of Pharmacy. In 1979, the Medical Analytics Department was established within the Faculty of Pharmacy (which ceased its activities in 2020). In 1978, the Faculty of Nursing was created which was transformed into the Faculty of Public Health in 2001 and into the Faculty of Health Sciences in 2008. Starting in 1989, the school was called the Academy of Medicine in Wrocław (Akademia Medyczna im. Piastów Śląskich). In 1992, the Post-Graduate Faculty of Medicine (existing until the academic year 2019/2020) was distinguished from the Faculty of Medicine. In 2000, the Department of Dentistry was transformed into the Faculty of Medicine and Dentistry. As a part of the school, liberal arts and social studies connected with medicine were also developed in units located within the structure of various departments of the AM. The Academy of Medicine in Wrocław existed until 2011 when the decision was made to transform it into Wrocław Medical University (Uniwersytet Medyczny im. Piastów Śląskich), functioning until now. The article presents the major stages in the history of medical schools in Wroclaw after 1945, taking into consideration the external factors that had an effect on the changes occurring in them. It also presents their results. It consists of three parts. The first one presents the most important aspects of the history of the Faculty of Medicine of Wrocław University and Wroclaw University of Science and Technology in the years 1945–1949. The second part discusses the history of the Academy of Medicine in the years 1950–2011, and the third one of Wrocław Medical University in the years 2011–2020. The article contains an extensive bibliography of studies concerning the history of these schools as well as the system of public medicine in Poland in the years 1945–2020, providing the context for their activities.

Academician Viktor Nikolaevich Shevkunenko (1872-1952) (on the 150<sup>th</sup> anniversary of the birth)

The outstanding Russian scientist and teacher in the field of topographic anatomy and operative surgery, one of the initiators of the creation of the Academy of Medical Sciences of the USSR and its full member (1944), Honored Scientist of the RSFSR (1935), winner of the Stalin Prize of the first degree (1943), Lieutenant General of the Medical Service (1943), Professor (1912) Viktor Nikolayevich Shevkunenko was born on February 17 (29 new style), 1872 in the county town of Mezen, Arkhangelsk province. In 1895, he graduated from the Imperial Military Medical Academy. From 1912 to 1948, he headed the Department of Operative Surgery and Topographic Anatomy of the Academy. V.N. Shevkunenko is the founder of the doctrine of the type and age variability of human anatomy. As a result of many years of research carried out by the staff of the department, atypical forms of the structure and location of organs and anatomical structures were described in detail, optimal accesses and rational technique were justified when performing surgical interventions on different organs, depending on the typical, sexual and age topographic and anatomical features of patients. V.N. Shevkunenko is the founder of a major Russian school in the field of operative surgery and topographic anatomy: 44 of his students became professors. Academician V.N. Shevkunenko died on July 3, 1952 and was buried at the Theological Cemetery in Leningrad.

Clinical assessment of nutrition status score and body mass index in newborns

Background: Fetal growth restriction can occur at any gestational period and is affected by maternal, placental and environmental factors. These factors can cause neonatal mortality or morbidity and long term sequalae. Thereby it is important to assess the nutritional status at birth. Clinical assessment of nutrition status score (CAN) assessment based on birth centile became important. Objectives: Aim was to compare CAN score and BMI birth centiles using pre-designated cut offs for assessing fetal nutrition. Materials and Methods: 1000 newborns cross-Sectional descriptive study. Department of Paediatrics, K.S. Hegde Medical Academy, Mangalore. Nov-2015 to June-2017. Inclusion criteria included term neonates with gestational age >37 completed weeks of gestation by dates or ultra-sonogram. Neonates with major congenital malformation or syndromes were excluded. Results: Out of 1000 newborns, 259 newborns (25.9%) had BMI below 10th centile out of which 99(9.9%) had BMI less than 3rd centile suggesting severe malnutrition. Malnutrition as per CAN Score was seen in 319(31.9%) infants. When CAN score and BMI was compared, among the 353 babies who had CAN score less than 25 indicating FM, only 129(36.5%) had BMI less than 10th centile. In 130 of the 259 infants with BMI less than 10th centile, CAN score was normal.

TYPES OF HEMODYNAMICS AND ASSOCIATIONS BETWEEN HEMODYNAMIC PARAMETERS AND BODY MASS INDEX IN MEDICAL STUDENTS

The study goal was to investigate hemodynamic parameters in medical students with different types of hemodynamics and their relationship with the body mass index. Materials and methods. A cross-sectional study of 2- and 3-year students of the North-Ossetian State Medical Academy (NOSMA) (133 female and 37 male subjects) was performed. Blood pressure, pulse rate, and anthropometric variables were measured. Hemodynamic parameters and body mass index were calculated. Statistical processing included frequency and correlation analyses and analysis of variance. Results. Overall, 60.6%, 36.5%, and 2.9% of the subjects had a eukinetic, hypokinetic, and hyperkinetic type of hemodynamics, respectively. Stroke volume (74.1 (68.6; 79.4)), cardiac output (7.8 (7.6; 7.8)), heart rate (100.4 (96.5; 109.9)), pulse pressure (50.0 (45.0; 60.0)), and rate pressure product (103.5 (90.3; 113.1)) were the highest in the hyperkinetic type group, and the lowest values of stroke volume (55.2 (54.2; 60.6)), cardiac output (4.3 (4.1; 5.0)), and pulse pressure (39.0 (30.0; 40.0)) were reported in the hypokinetic type group. Correlations between the evaluated parameters and body mass index (r=0.17–0.46) have been established. In the hypokinetic and eukinetic type groups, CO, SBP, DBP, PP, RPP, and AP were higher in subjects with BMI ≥ 25 compared with those with BMI < 25. Conclusions. The eukinetic type of hemodynamics is the most common among medical students, and is predominantly inherent in females, while the hypokinetic type is more common among males. HR, SV, CI, CO, PP, RPP, KI increased and TPVR, RPVR, SBP, DBP, MBP decreased from the hypokinetic to hyperkinetic types. The observed within-group trends in the evaluated hemodynamic parameters were consistent with the types of hemodynamics both in female and male subjects. Regardless of the type of hemodynamics, the hemodynamic parameters and adaptation potential of the cardiovascular system decrease in subjects with BMI ≥ 25. Higher BMI was associated with a significantly greater cardiovascular load and AP of the cardiovascular system.

Experience in the use of low-temperature plasma in the therapy of radiation reactions.

The use of low-temperature plasma is a modern and developing direction in medicine, including rehabilitation. Low-temperature plasma (LTP) has a high antiseptic, wound-healing activity, and is also a safe method of physical exposure. In the in-patient facility of clinical unit of Federal State Budgetary Educational Institution of Further Professional Education Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation named after Prof. Yu.N. Kasatkinа, a patient was treated with low-temperature argon plasma after selective right cervical lymph node dissection, resection of the mandible, and tissues of the oral floor with defect plasty with a fibular autograft for cancer of the gingival mucosa of the mandible on the right pT4aN0M0, stage IVa. In the process of EBRT (external beam radiation therapy), the patient developed a complication in the form of a local radiation reaction with the formation of a fistulous opening in the area of the postoperative scar. The fistulous opening and the affected area were treated with a cooled air-plasma flow. During the continued use of LTP, the termination of pyorrhea, a decrease in hyperemia and edema in the area of tissues damaged by ionizing radiation were noted. The patient was promptly continued radiation therapy.
 Thus, the use of this therapeutic factor in the program of medical rehabilitation is an effective way of local impact on the pathological focus, allows you to achieve a quick reparative effect, eliminates and prevents the development of bacterial complications. In addition, the use of an air-plasma flow contributes to the rapid relief of manifestations of radiation reactions, having a beneficial effect on damaged tissues, as well as shortening the rehabilitation period for severe cancer patients in the postoperative period and during the course of EBRT. The results of LTP action have a positive effect on the general condition of patients and improve their quality of life.

A survey of physician opinions in Russia in the field of pharmacogenetics of cardiovascular disease.

Aims: To study the readiness of Russian physicians with experience and younger physicians undergoing clinical residency and postgraduate education to apply pharmacogenetic testing in their clinical practice. Materials & methods: The sociological study involved physicians (n =378) living in different regions of the Russian Federation, as well as residents and graduate students (n =185) of the Russian Medical Academy of Continuing Professional Medical Education. The survey consisted of 35 questions, and 23 were created on the online platform of professional surveys, Testograf.ru. Results: Every second respondent was willing to use pharmacogenetic testing in clinical practice to predict the efficacy and safety of medications in patients with cardiovascular disease (p=0.06). Factors impeding the clinical implementation of pharmacogenetic testing in Russia were identified: physicians' ignorance of pharmacogenetics (p=0.015), a lack of pharmacogenetic testing in clinical guidelines and treatment standards (p=0.175) and a lack of economic justification for using pharmacogenetic testing (p=0.320). Conclusion: Russian physicians have a positive attitude toward pharmacogenetic testing. However, the level of test implementation remains low.

Predominance of t355/ST152/SCCmec V clonal type among PVL-positive MRSA isolates in a tertiary care hospital in Belgrade, Serbia.

Epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) is continually changing. Frequency of genotypes typical for community-associated MRSA (CA-MRSA) is increasing in hospitals, as well as resistance to antimicrobial agents. Moreover, different clones predominate in different geographic regions, and temporal shifts occur in the predominant clonal type. The aim of this study was to estimate the prevalence of MRSA, CA-MRSA and PVL-positive MRSA isolates from patients hospitalised in the Military Medical Academy (MMA) and from outpatients, and to perform genotyping of PVL-positive MRSA isolates. MRSA isolates were obtained by standard microbiological techniques. PVL-positive MRSA were detected by single PCR. Determination of SCCmec types in MRSA isolates was done using multiplex PCR and genotyping of PVL-positive MRSA by PFGE, MLST and spa typing. The prevalence of MRSA among S. aureus isolates from different clinical specimens was 43.4%. In outpatients the prevalence of MRSA was 3.2%. SCCmec types specific for CA-MRSA were found in 26% of MRSA isolates from hospitalised patients. In groups, hospitalised patients and outpatients, the prevalence of PVL-positive MRSA isolates was 4%, and all of them harboured SCCmec type V genetic element. PFGE revealed minor differences between four groups of PVL-positive MRSA isolates, but all of them belonged to ST152, and all except one were of the t355 spa type. High prevalence of MRSA and CA-MRSA in MMA, especially the presence of PVL-positive CA-MRSA, represent a serious health threat for patients. Genotype t355/ST152/SCCmec V is the dominant MRSA clone among PVL-positive CA-MRSA.

Opportunities for Distance Practical Training in Medicine

The report presents an analysis of the effectiveness of remote training in practical skills and two years of experience in conducting Olympiads among students of Amur State Medical Academy in a remote format. The methodological base of remote training in practical skills has been obtained.

Control of the Purity of 93% Oxygen Obtained from the Air by Pressure Swing Adsorption

The assessment of the quality of 93% oxygen obtained from the air by pressure swing adsorption (PSA) presents an important challenge for applied research. Such an assessment provides a possibility to guarantee the safety of oxygen therapy using both stationary and portable PSA-based oxygen concentrators. In this article, the experts of the Scientific Centre for Expert Evaluation of Medicinal Products and S.M. Kirov Military Medical Academy offer their recommendations for the implementation of monograph 2.2.0037.22 Oxygen (93 per cent) in civil healthcare organisations or military medical units. The publication of this monograph, which was approved by order No. 126 issued by the Ministry of Health of the Russian Federation on 01.03.2022, became the endpoint of the experts’ cooperation aimed at the inclusion of 93% oxygen into the Russian State Register of Medicinal Products.

Experience of the army internship of military medical academy cadets on stomatology

BACKGROUND: An organized acquisition of practical skills at the military level, in the positions of dentists of a medical company (military medical organization), by cadets studying stomatology is relevant.
 AIM: The purpose is to highlight the tasks solved during the military training of cadets, the methodology of their implementation and the results achieved.
 MATERIAL AND METHODS: Cadets in their fifth year of the fourth pharmacy of the Faculty of Training Doctors for the Navy who were studying stomatology started their clinical practice (military internship). The departments of organization and tactics of the medical service, general and military epidemiology, general and military hygiene, military medical supplies, officials of the educational and methodological department, and representatives of the faculty took part in the preparation and conduct of the military internship. The training of cadets included the main provisions of methodological recommendations, documents worked out during the internship, and recommendations from representatives of departments focusing on certain profile issues.
 RESULTS: The cadets fully completed the military internship program in the stomatology specialty, received positive feedback from the commanders of military units, and successfully defended the reports on the work done. The survey showed that the cadets who were constantly located in remote military units managed to work out the largest number of manipulations, which allowed them to determine the real conditions of their future service. They were also most satisfied with the results of their practical work. The acquired knowledge enabled the cadets to adjust their theoretical training. The vast majority of cadets requested increasing the internship period to 4 weeks. All streams completed the internship without comments due to the responsible attitude of the internship managers and the assistance of officials of the medical service of the Western Military District and the Baltic Fleet.
 CONCLUSION: The military internship allowed the cadets to get acquainted with real military service, instilling a sense of pride in belonging to the Armed Forces of Russia. The experience gained allowed us to focus on planning internships in military units, whereas the number of cadets specializing in dentistry should be no more than two in one military unit. It is desirable to expand the geography of the internship. Thus, the duration of clinical practice was recommended to be at least 4 weeks. A more in-depth study of the documentation conducted in the dental office and as a part of the medical service is necessary. Publishing methodological recommendations on the organization of clinical practice (military internship) of cadets studying in the stomatology specialty is desirable.

Possibilities of Simulation Technologies in the Implementation of Scientific Strategic Projects. #NeuroCHEburashka

The paper presents a project for the strategic development of the Federal State Budgetary Educational Institution of Higher Education Amur State Medical Academy for 2022–2030. The role and capabilities of the Accreditation and Simulation Center and simulation medical technologies in the implementation of this project are determined. The main vectors of network interaction with other universities, scientific organizations of the Region and the Russian Federation, areas of international cooperation are presented.

Treatment Options in Patients Suffering from Hemolytic-Uremic Syndrome: The Serbian Military Medical Academy Experience

Abstract Hemolytic-Uremic Syndrome (HUS) is a clinical syndrome with a triad of non-immune Microangiopathic Hemolytic Anemia (MAHA), thrombocytopenia and renal failure. Together with the Thrombotic Thrombocytopenic Purpura (TTP), it belongs to a group of diseases characterized as the Thrombotic Microangiopathy (TMA), which represents a microvascular occlusive disorder with the formation of a predominantly thrombocytic thrombus in the renal and/or systemic circulation. In the period starting from 2001 to 2017, 14 patients with a HUS were diagnosed at the Clinic for Nephrology (unfortunately ADAMTS 13 could not have been done due to technical reasons). In a retrospective clinical laboratory analysis and monitoring, we obtained the following results. Out of 14 patients, 10 were female (or 71.43%) and 4 were male (28.57%), the youngest patient was aged 17 and the oldest one 78, the average age of our patients was 55.33 years, the annual number of patients with the diagnosis of HUS was 0.93 patients per year, or 0.00116 in relation to the total number of patients treated. After monitoring the patients individually for the period ranging from 1 to 14 years, a stable remission was achieved in 5 patients, while a chronic renal insufficiency occurred in 3 patients. In two of our patients, a percutaneous kidney biopsy was performed with pathohistological findings described in references. Having done this retrospective analysis, we can conclude that the survival and complications of this rare, but serious disease correspond to the available world data.

Scientific heritage of professor G. V. Illyuvieva

Our mining industry has been built by women as well as men. A mining processing engineer, a graduate of the Leningrad Mining Institute, a specialist in the field of ore flotation, sorption, and extraction, head of the Department of General and Physical Chemistry of the Mining Institute for 16 years (1966–1981), and a participant in the Great Patriotic War, Galina Viktorinovna Illuvieva will be remembered by generations to come as an outstanding researcher, a talented leader, and a mentor. The article systematizes documentary material on the life of Galina Illuvieva and analyzes her contribution in the scientific and pedagogical fields. Her research resulted in improved technology for the complex processing of ores at a number of deposits of ferrous, non-ferrous, and rare metals, and coal. Under the leadership of Galina Illuvieva, the Department of General and Physical Chemistry reached a new milestone in significantly increasing its material and technical resources and the amount of work commissioned by the industry and ensuring the successful defense of candidate dissertations on urgent scientific and technical topics. As a teacher, Galina Illuvieva enjoyed high prestige and respect among students. During the war, she worked selflessly as a scrub nurse in the besieged Leningrad at the Military Medical Academy and at the evacuation hospital. Galina Illuvieva was awarded two medals for her courage during the Great Patriotic War and held the Order of Lenin and multiple medals for outstanding scientific, pedagogical, and social work.

Dentistry and maxillofacial surgery during the Leningrad siege

Military doctors, including Military Medical Academy named after S.M. Kirov employees, played an important role in the USSR victory over Nazi Germany. This has historical information. However, the work of military dentists in the besieged Leningrad conditions is practically not covered.
 To provide information about the professional activities of military dentists and maxillofacial surgeons during the blockade of Leningrad.
 The study included official statistical reports on the activities of medical units, research, and dissertations, materials from scientific conferences, as well as books, monographs, and scientific articles that testify to the activities of medical workers during the blockade of Leningrad. During the blockade of Leningrad, the work of military dentists provides an example of complex medical and diagnostic problem intensive solutions against the backdrop of an acute financial, material, and labor resource shortage. Specialized medical care for the maxillofacial wound under the siege of Leningrad was provided in the dental clinic of the Military Medical Academy and evacuation hospitals. A quarter of those wounded in the face simultaneously had lesions in other areas, such as the limbs, ears, nose, and throat organs, eyes, etc. With a significant percentage of severe wounds, a low percentage of fatal cases of wounds in the face, accounting for approximately 1.5% of the total number of wounds. During the blockade of the Neva City, military dentists significantly improved surgical and orthopedic methods of treating maxillofacial wounded and dental patients, which is most fully presented in the 6th volume of the Experience of Soviet Medicine in the Great Patriotic War of 19411945 (1951), where, among the 22 members of the team of authors, 18 are from Leningrad. According to the Leningrad Front, the total number of military personnel that returned to military service was 810% higher than the average percentage of those fully recovered on all fronts in different years of the war.

Helena Biantovskaya Fedukowicz: An epitome of contagious passion and spirit.

Helena Biantovskaya Fedukowicz: An epitome of contagious passion and spirit.

Clinical and epidemiological features of psoriasis in the Republic of Uzbekistan

BACKGROUND: Psoriasis is one of the most common dermatoses. The disease has a negative impact on every aspect of the patients life ― social, physical and psychological. Psoriasis is accompanied by a marked deterioration in the quality of life of patients, which often leads to their social maladaptation.
 AIMS: This study is aimed at assessing the nature of epidemiological and clinical manifestations of psoriasis in the Republic of Uzbekistan.
 MATERIALS AND METHODS: The data of the population register of psoriatic diseases created on the basis of the Republican Skin and Venereological Clinical Hospital the city of Tashkent, the Republican Specialized Scientific and Practical Center of Dermatology and Cosmetology of the Republic of Uzbekistan were studied. A retrospective analysis of case histories for the period 20152019 was also carried out at the clinical base of the Department of Dermatovenerology of the Tashkent Medical Academy.
 RESULTS: The prevalence of psoriasis among the general population of the Republic of Uzbekistan from 2010 to 2020 during the study period significantly increased, especially in the age group of 1529 years. Men suffer from psoriasis more often, this disease is characterized by an earlier onset of the disease (age group up to 40 years). The most common clinical form of psoriasis is vulgar psoriasis.
 CONCLUSIONS: There is a clear need to improve the quality and increase the amount of data related to the epidemiology of psoriasis in the Republic of Uzbekistan. Diagnostic criteria and reports on morbidity and prevalence should be standardized.