Background: Of the 377 adult patients at the regional Cystic Fibrosis (CF) Unit, Leeds, 166 (44%) have Totally Implantable Vascular Access Devices (TIVAD). For the remaining 211 (56%) requiring intravenous antibiotic therapy, peripheral longlines are the preferred option for prolonged IV access. Following a reduction in medical cover (FY2) the CF Clinical Nurse Specialists (CNS) underwent training to extend their role and insert peripheral longlines. We aimed to compare the patient experience and complication rates following insertion by doctors or CNS. Methods: CNS received formal training on longline insertion, and achieved practical competencies for this technique. An audit was completed over a 9 month period measuring patient satisfaction and associated complications in 9 key areas. Patient satisfaction was measured on a scale of 1−4 (1 = poor, 4 = excellent). Results: 62 insertions were recorded (36 by doctors, 26 by CNS). There were no differences in patient satisfaction score [Median Patient satisfaction score was 3.5 (doctors) v 4.0 (CNS)], Mean Patency of longline was [10.8 days (doctors) v 10.2 days (CNS)], percentage insertions requiring more than 1 attempt [24% (doctor) v 19% (CNS)] or infection rates. Difference in waiting time to longline insertion was significant [40 min (doctor) vs 20 min (CNS); p< 0.05]. Conclusion: CNS achieved the same patient satisfaction scores and low complication rates as medical staff, whilst reducing waiting times. Extended CNS roles improve the patient experience.