Navigation Mechanism Research Articles

Reactivation of behavioral activity during sharp waves: A computational model for two stage hippocampal dynamics

The rodent hippocampus is known to exhibit two very distinctive patterns of activity: theta with place selective cells firing during exploratory behavior and sharp waves (SPWs) associated with collective discharges in the CA3 during slow wave sleep (SWS), inactivity while awake and consummatory behavior. A great deal of evidence has demonstrated that the cells activated during SPWs events are representative of previous behavioral activity, which suggests an important functional role of off-line learning and consolidation for these SPWs events. Supporting this view, forward, and more recently, reverse replay of linear track behavioral sequences have been reported in rodent's hippocampal place cells during SPWs. We demonstrate here that these patterns of reactivation can be successfully reproduced by relying on a computational model of the hippocampus with theta phase precession and synaptic plasticity during theta rhythm. Two mechanisms are proposed to initiate SPWs events: random reactivation in the presence of rapid, irregular subthreshold inputs and place selective cell activations. In 2D navigation computational experiments, rather than observing the perfect replay of experienced pathways, new pathways "experienced during immobility" emerge. This suggests a neural mechanism for shortcut navigation.

Marine Turtles Use Geomagnetic Cues during Open-Sea Homing

Marine turtles are renowned long-distance navigators, able to reach remote targets in the oceanic environment; yet the sensory cues and navigational mechanisms they employ remain unclear [1, 3]. Recent arena experiments indicated an involvement of magnetic cues in juvenile turtles' homing ability after simulated displacements [4, 5], but the actual role of geomagnetic information in guiding turtles navigating in their natural environment has remained beyond the reach of experimental investigations. In the present experiment, twenty satellite-tracked green turtles (Chelonia mydas) were transported to four open-sea release sites 100-120 km from their nesting beach on Mayotte island in the Mozambique Channel; 13 of them had magnets attached to their head either during the outward journey or during the homing trip. All but one turtle safely returned to Mayotte to complete their egg-laying cycle, albeit with indirect routes, and showed a general inability to take into account the deflecting action of ocean currents as estimated through remote-sensing oceanographic measurements [7]. Magnetically treated turtles displayed a significant lengthening of their homing paths with respect to controls, either when treated during transportation or when treated during homing. These findings represent the first field evidence for the involvement of geomagnetic cues in sea-turtle navigation.

Orientation and navigation in bats: known unknowns or unknown unknowns?

Bats have been extensively studied with regard to their ability to orient, navigate and hunt prey by means of echolocation, but almost nothing is known about how they orient and navigate in situations such as migration and homing outside the range of their echolocation system. As volant animals, bats face many of the same problems and challenges as birds. Migrating bats must relocate summer and winter home ranges over distances as far as 2,000 km. Foraging bats must be able to relocate their home roost if they range beyond a familiar area, and indeed circumstantial evidence suggests that these animals can home from more than 600 km. However, an extensive research program on homing and navigation in bats halted in the early 1970s. The field of bird navigation has advanced greatly since that time and many of the mechanisms that birds are known to use for navigation were not known or widely accepted at this time. In this paper I discuss what is known about orientation and navigation in bats and use bird navigation as a model for future research in bat navigation. Technology is advancing such that previous difficulties in studying orientation in bats in the field can be overcome and so that the mechanisms of navigation in this highly mobile animal can finally be elucidated.

An Archaeal Peptidase Assembles into Two Different Quaternary Structures

Cellular proteolysis involves large oligomeric peptidases that play key roles in the regulation of many cellular processes. The cobalt-activated peptidase TET1 from the hyperthermophilic Archaea Pyrococcus horikoshii (PhTET1) was found to assemble as a 12-subunit tetrahedron and as a 24-subunit octahedral particle. Both quaternary structures were solved by combining x-ray crystallography and cryoelectron microscopy data. The internal organization of the PhTET1 particles reveals highly self-compartmentalized systems made of networks of access channels extended by vast catalytic chambers. The two edifices display aminopeptidase activity, and their organizations indicate substrate navigation mechanisms different from those described in other large peptidase complexes. Compared with the tetrahedron, the octahedron forms a more expanded hollow structure, representing a new type of giant peptidase complex. PhTET1 assembles into two different quaternary structures because of quasi-equivalent contacts that previously have only been identified in viral capsids.

A computational framework for retrieval of document fragments based on decomposition schemes in engineering information management

Retrieval of document fragments has a great potential for application in engineering information management. Frequently engineers have neither the time nor inclination to sift through long documents for small pieces of useful information. Yet it is frequently in the form of one or more long documents that the information that they seek is presented. Supporting the delivery of the right information, in the right format and in the right quantity motivates the search for better ways of handling document sub-components or fragments. Document fragment retrieval can be facilitated using modern computational technologies. This paper proposes a novel framework for information access utilising state-of-the-art computational technologies and introducing the use of multiple document structure views through decomposition schemes. The framework integrates document structure study, mark-up technologies, automated fragment extraction, faceted classification and a document navigation mechanism to achieve the target of retrieval of specific document fragments using precise, complex queries. These disparate elements have been brought together in an exploratory Engineering Document Content Management System (EDCMS). Using this, investigations using representative engineering documents have shown that information users can access and retrieve document content – at fragment level rather than at document level – both through data in a document and document metadata, through different perspectives and at different granularities, and simultaneously across multiple documents as well as within a single document.

When to Go, Where to Stop

The ability to move, at some stage in the life cycle, is fundamental to success in life. Passive drift in water columns conferred a selective advantage for early life, offering an escape from starvation and genetic uniformity. Since then, organisms have evolved many ways to disperse and migrate in response to the pressures of finding resources, escaping predators, seeking out mates and suitable breeding grounds, and distancing themselves from family. Dispersal in its broadest sense means movement away from the birthplace. Strictly speaking, migration involves travel in a periodically and geographically predictable way, whether it occurs just once or many times. In this issue, Science deals with what we know, what we need to know, and how we are going to find out more about both of these movement types. In plants, the spore, seed, or fruit is typically the unit of dispersal. Although the many morphological adaptations for their dispersal are known, until now, researchers have been unable to determine the distances traveled or the proportion of dispersal events that lead to seedlings. In one Perspective (p. 786), Nathan describes recent developments in the modeling and measurement of the long-distance dispersal of plants. A News story by Holden (p. [779][1]) discusses the push to come up with a theoretical framework, not just for plants, but for all moving organisms. Organisms also disperse in reaction to changing habitats and climate. The Perspective by Kokko and Lopez-Sepulcre (p. [789][2]) discusses the selective forces affecting this ability in animals and how dispersal translates into range expansions and contractions. Kintisch (p. 776) describes the challenges for marine scientists assessing how climate change may affect oceangoing species. Humans have been great dispersers. Colonizing new habitat has been a hallmark of human ecology over the past million years or so. In a Review (p. [796][3]), Mellars considers recent advances in archaeology and genetics that are illuminating the controversies over the routes taken by ancient peoples in the colonization of Asia 40,000 to 60,000 years ago. Two Perspectives consider migration: Holland et al. (p. 794) focus on migrating insects, which tend to travel in established geographical patterns across several generations rather than returning to their birthplace, and Alerstam (p. [791][4]) discusses the accumulating and sometimes conflicting evidence about the navigational mechanisms used by animals (particularly birds) in long-distance annual migrations. In a related Report (p. 837), Muheim et al. describe the role of polarized light at dawn and sunset in calibrating the magnetic compasses of migrating birds. A News story by Morell (p. 783) describes a new model that will clarify the mix of genes and environmental responses underlying successful bird migration. As News stories by Blackburn and Holden (p. 780) and Unger (p. [784][5]) point out, ingenuity and persistence are beginning to pay off in new techniques for following organisms, be they fish, crabs, jellyfish, rhinos, or polar bears. Thanks to these advances, the study of the ecology and evolution of movement is charging ahead and unearthing the challenges faced by organisms in dispersing and migrating in a world undergoing anthropogenic change. [1]: /lookup/doi/10.1126/science.313.5788.779 [2]: /lookup/doi/10.1126/science.1128566 [3]: /lookup/doi/10.1126/science.1128402 [4]: /lookup/doi/10.1126/science.1129048 [5]: /lookup/doi/10.1126/science.313.5788.784

Small brains, smart computations: Vision and navigation in honeybees, and applications to robotics

Flying insects provide a clear demonstration that living organisms can display surprisingly competent mechanisms of guidance and navigation, despite possessing relatively small brains and simple nervous systems. Consequently, they are proving to be excellent organisms in which to investigate how visual information is exploited to guide locomotion and navigation. Three illustrative examples are described here, in the context of navigation to a destination. Bees negotiate narrow gaps by balancing the speeds of the images in the two eyes. The flight speed is regulated by holding constant the average image velocity as seen by the two eyes. Smooth landings on a horizontal surface are achieved by holding image velocity constant as the surface is approached, thus automatically ensuring that the flight speed is close to zero at touchdown. Tests of the feasibility of some of these navigational strategies, by implementation in robots, are described.

Zooming versus multiple window interfaces

In order to investigate large information spaces effectively, it is often necessary to employ navigation mechanisms that allow users to view information at different scales. Some tasks require frequent movements and scale changes to search for details and compare them. We present a model that makes predictions about user performance on such comparison tasks with different interface options. A critical factor embodied in this model is the limited capacity of visual working memory, allowing for the cost of visits via fixating eye movements to be compared to the cost of visits that require user interaction with the mouse. This model is tested with an experiment that compares a zooming user interface with a multi-window interface for a multiscale pattern matching task. The results closely matched predictions in task performance times; however error rates were much higher with zooming than with multiple windows. We hypothesized that subjects made more visits in the multi-window condition, and ran a second experiment using an eye tracker to record the pattern of fixations. This revealed that subjects made far more visits back and forth between pattern locations when able to use eye movements than they made with the zooming interface. The results suggest that only a single graphical object was held in visual working memory for comparisons mediated by eye movements, reducing errors by reducing the load on visual working memory. Finally we propose a design heuristic: extra windows are needed when visual comparisons must be made involving patterns of a greater complexity than can be held in visual working memory.

Navigation of marine, freshwater and coastal animals: concepts and current problems

The animals from the environments focused on here share the same navigational mechanisms with terrestrial animals. However, some of them seem to rely on additional ways of detecting and/or processing navigational cues, some of which are perhaps still unknown. A classification of the mechanisms of navigation is given. This is based on the source of information that animals use to head for their targets. A selected series of phenomena of current interest is presented, starting with olfactory beaconing in oceanic birds, which allows the detection of patchily distributed food and productive areas from long distances. Animals of sandy beaches rely on an array of mechanisms of orientation, which have an adaptive value for their ecotonal system. As some species are capable of using both the moon and sun compass in orientation, attention and experiments are focused on the significance of these celestial cues in the navigational process. Two clocks of different periods, one of which would appear to regulate both the activity rhythm and the sun compass, are presumed to underlie the two compass mechanisms. The feats of global navigators in and over the oceans are especially puzzling considering their ability of homing to the natal and nesting sites after long lasting, extended wandering in the open ocean, and of pinpointing tiny, isolated oceanic islands. The existent literature allows comparison of the navigational capabilities of oceanic birds with those of sea turtles. Their performances in natural conditions seem to be similar, but sea turtles exhibit a reduced capacity of compensation for experimental relocation. Capacity of positioning based on geomagnetic parameters has been indicated for sea turtles through laboratory experiments, but this is not confirmed by the routes of magnetically disturbed turtles tracked while migrating or attempting to compensate for relocation. Also albatrosses with fitted magnets are not disturbed in their homing.

Derivation of a continuum model and its electric equivalent-circuit representation for ionicpolymer–metal composite (IPMC) electromechanics

Biomedical engineering applications of ionic polymer–metal composites such as motiondevices for endoscopy, pumps, valves, catheter navigation mechanisms and spinal pressuresensors make it important to properly model IPMCs for engineering design. In particular,IPMC continuum models and their electric equivalent circuit representation are critical to amore efficient design of IPMC devices. In this paper, we propose a new continuumelectromechanical model to understand and predict the electrical/mechanicalbehavior of the IPMC. An IPMC lumped-parameter circuit is derived from itscontinuum model to predict the relationship between its voltage and current signals.Although based on previous works of Shahinpoor and Nemat-Nasser, our modelwas derived on a macroscopic level, the water effects were assumed negligiblewhen compared with the electrical effects of mobile ions for the IPMC motion,the model parameters were clearly identified in their physical meaning, and anequivalent-circuit IPMC model was determined from the established continuumelectromechanical model. Experiments are done with two IPMC pieces having differentdimensions, which were previously immersed in a sodium solution. The IPMCs arecurrent driven, the transverse displacement and voltage signals being measured fordifferent current values, avoiding the water electrolysis phenomenon. Simulationsusing the analytic models derived are compared with the experimental results andthey are found to predict the electrical and mechanical relations very accurately.

Semantically enriched navigation for indoor environments

Location-based mobile services have been in use, and studied, for a long time. With the proliferation of wireless networking technologies, users are mostly interested in advanced services that render the surrounding environment (i.e., the building) highly intelligent and significantly facilitate their activities. In this paper our focus is on indoor navigation, one of the most important location services. Existing approaches for indoor navigation are driven by geometric information and neglect important aspects, such as the semantics of space and user capabilities and context. The derived applications are not intelligent enough to catalytically contribute to the pervasive computing vision. In this paper, a novel navigation mechanism is introduced. Such navigation scheme is enriched with user profiles and the adoption of an ontological framework. These enhancements introduce a series of technical challenges that are extensively discussed throughout the paper.

Community Building around Encyclopaedic Knowledge

This paper gives a brief overview of current technologies in systems handling encyclopaedic knowledge. Since most of the electronic encyclopaedias currently available are rather static and inflexible, greatly enhanced functionality is introduced that enables users to work more effectively and collaboratively. Users have the ability, for instance, to add annotations to every kind of object and can have private and shared workspaces. The techniques described employ user profiles in order to adapt to different users and involve statistical analysis to improve search results. Moreover, a tracking and navigation mechanism based on trails is presented. The second part of the paper details community building around encyclopaedic knowledge with the aim to involve ?plain? users and experts in environments with largely editorial content. The foundations for building a user community are specified along with significant facets such as retaining the high quality of content, rating mechanisms and social aspects. A system that implements large portions of the community-related concepts in a heterogeneous environment of several largely independent data sources is proposed. Apart from online and DVD-based encyclopaedias, potential application areas are e-Learning, corporate documentation and knowledge management systems.

Route Recapitulation and Route Loyalty in Homing Pigeons: Pilotage From 25 km?

We utilised precision Global Positioning System (GPS) tracking to examine the homing paths of pigeons (Columba livia) released 20 times consecutively 25 km from the loft. By the end of the training phase, birds had developed highly stereotyped yet individually distinct routes home, with detailed recapitulation evident at each stage of the journey. Following training, birds also participated in a series of releases from novel sites at perpendicular distances of up to 3 km from their established routes. Results showed that subjects were attracted back to their established routes and recapitulated them from the point of contact. Naïve conspecifics (yoked controls) released from the same off-route sites confirmed that the experienced birds' route choices were not influenced by constraints exerted by terrain features, but that increased experience with the general area conferred a homing advantage in the form of more efficient flight tracks, even from these novel sites. Patterns in the paths taken by experienced birds to rejoin their established routes are discussed with reference to navigational mechanisms employed by homing pigeons in their familiar area.

Mechanisms of animal global navigation: comparative perspectives and enduring challenges

Animals navigate over a range of distances, but it has been the global navigation of species migrating among spatially restricted, seasonal homes separated by thousands of kilometers that continues to defy a thorough mechanistic explanation. We survey the navigational behavior of migratory salmon, whales, sea turtles, and birds, as well as dispersing monarch butterflies, to promote the idea that an explicitly comparative approach to global navigation can provide insight into the evolution and properties of navigational mechanisms. The navigational abilities of migrant birds and sea turtles are used to illustrate the concepts of true navigation and vector navigation, leading us to consider the selective forces that might shape the evolution of navigational mechanisms. We propose that different navigational mechanisms, with different scales of accuracy, are likely employed during the course of migration. Furthermore, superficially similar global migratory behavior in different taxonomic groups is likely characterized by different sensory, representational and neural mechanisms reflective of groupspecific adaptation to the physical properties of a migratory environment.

Global and local spatial landmarks: their role during foraging by Columbian ground squirrels (Spermophilus columbianus)

Locating food and refuge is essential for an animal's survival. However, little is known how mammals navigate under natural conditions and cope with given environmental constraints. In a series of six experiments, I investigated landmark-based navigation in free-ranging Columbian ground squirrels (Spermophilus columbianus). Squirrels were trained individually to find a baited platform within an array of nine identical platforms and artificial landmarks set up on their territories. After animals learned the location of the food platform in the array, the position of the latter with respect to local artificial, local natural, and global landmarks was manipulated, and the animal's ability to find the food platform was tested. When only positions of local artificial landmarks were changed, squirrels located food with high accuracy. When the location of the array relative to global landmarks was altered, food-finding accuracy decreased but remained significant. In the absence of known global landmarks, the presence of a familiar route and natural local landmarks resulted in significant but not highly accurate performance. Squirrels likely relied on multiple types of cues when orienting towards a food platform. Local landmarks were used only as a secondary mechanism of navigation, and were not attended to when a familiar route and known global landmarks were present. This study provided insights into landmark use by a wild mammal in a natural situation, and it demonstrated that an array of platforms can be employed to investigate landmark-based navigation under such conditions.

Dramatic Orientation Shift of White-Crowned Sparrows Displaced across Longitudes in the High Arctic

Advanced spatial-learning adaptations have been shown for migratory songbirds, but it is not well known how the simple genetic program encoding migratory distance and direction in young birds translates to a navigation mechanism used by adults. A number of convenient cues are available to define latitude on the basis of geomagnetic and celestial information, but very few are useful to defining longitude. To investigate the effects of displacements across longitudes on orientation, we recorded orientation of adult and juvenile migratory white-crowned sparrows, Zonotrichia leucophrys gambelii, after passive longitudinal displacements, by ship, of 266-2862 km across high-arctic North America. After eastward displacement to the magnetic North Pole and then across the 0 degrees declination line, adults and juveniles abruptly shifted their orientation from the migratory direction to a direction that would lead back to the breeding area or to the normal migratory route, suggesting that the birds began compensating for the displacement by using geomagnetic cues alone or together with solar cues. In contrast to predictions by a simple genetic migration program, our experiments suggest that both adults and juveniles possess a navigation system based on a combination of celestial and geomagnetic information, possibly declination, to correct for eastward longitudinal displacements.

Sensitivity to dimethyl sulphide suggests a mechanism for olfactory navigation by seabirds

Petrels, albatrosses and other procellariiform seabirds have an excellent sense of smell, and routinely navigate over the world's oceans by mechanisms that are not well understood. These birds travel thousands of kilometres to forage on ephemeral prey patches at variable locations, yet they can quickly and efficiently find their way back to their nests on remote islands to provision chicks, even with magnetic senses experimentally disrupted. Over the seemingly featureless ocean environment, local emissions of scents released by phytoplankton reflect bathymetric features such as shelf breaks and seamounts. These features suggest an odour landscape that may provide birds with orientation cues. We have previously shown that concentrated experimental deployments of one such compound, dimethyl sulphide (DMS), attracts procellariiforms at sea, suggesting that some species can use it as a foraging cue. Here we present the first physiological demonstration that an Antarctic seabird can detect DMS at biogenic levels. We further show that birds can use DMS as an orientation cue in a non-foraging context within a concentration range that they might naturally encounter over the ocean.

Neural guidance molecules regulate vascular remodeling and vessel navigation

The development of the embryonic blood vascular and lymphatic systems requires the coordinated action of several transcription factors and growth factors that target endothelial and periendothelial cells. However, according to recent studies, the precise "wiring" of the vascular system does not occur without an ordered series of guidance decisions involving several molecules initially discovered for axons in the nervous system, including ephrins, netrins, slits, and semaphorins. Here, we summarize the new advances in our understanding of the roles of these axonal pathfinding molecules in vascular remodeling and vessel guidance, indicating that neuronal axons and vessel sprouts use common molecular mechanisms for navigation in the body.

Hypermedia Systems Development Practices: A Survey

Merely calling a system doesn't necessarily imply that its software design differs much from that of a traditional system. When Web-based systems assume hypermedia functionality they become substantively different from a design perspective. Hypermedia technologies support much richer user interfaces, more complex navigation mechanisms, and more varied forms of information than traditional computer systems. In recent years, hypermedia systems (particularly Web-based ones) have grown in complexity and scope as they've begun to involve critical organizational activities such as customer support, sales and marketing, and technical support.

An overview of insect-inspired guidance for application in ground and airborne platforms

Flying insects provide a clear demonstration that living organisms can display surprisingly competent mechanisms of guidance and navigation, despite possessing relatively small brains and simple nervous systems. Consequently, they are proving to be excellent organisms in which to investigate how visual information is exploited to guide locomotion and navigation. Four illustrative examples are described here, in the context of navigation to a destination. Bees negotiate narrow gaps by balancing the speeds of the images in the two eyes. Flight speed is regulated by holding constant the average image velocity as seen by the two eyes. This automatically ensures that flight speed is reduced to a safe level when the passage narrows. Smooth landings on a horizontal surface are achieved by holding image velocity constant as the surface is approached, thus automatically ensuring that flight speed is close to zero at touchdown. Roll and pitch are stabilized by balancing the signals registered by three visual organs, the ocelli, that view the horizon in the left, right and forward directions respectively. Tests of the feasibility of these navigational strategies, by implementation in robots, are described.