Strength Measurements Research Articles

Cluster analysis of sarcopenia in older adults: significant factors contributing to disease severity.

The European Working Group on Sarcopenia in Older People (EWGSOP2) defines sarcopenia as a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age. New findings on the hormonal and metabolic characteristics of patients with sarcopenia have aided in developing more targeted therapeutic strategies. However, treating older patients with sarcopenia still poses a number of challenges. Despite numerous studies on sarcopenia, no comprehensive phenotyping of older sarcopenic patients has yet to be offered. Cluster analysis has been successfully used to study various diseases. It may be extremely advantageous for collecting data on specific sarcopenia progressions based on a simultaneous assessment of a whole range of factors. To identify disease progression specific to older patients based on cluster analysis of blood biomarkers and lifestyle. This study included 1709 participants aged 90 and older. The median age was 92. Seventy-onepercent of participants were female. Participants underwent a comprehensive geriatric assessment and had their metabolic, hormonal, andinflammatory blood biomarkers measured. The data were analyzed and clustered usingthe Rprogramming language. Seven sarcopenia clusters were identified. The most significant variables, indescending order, were malnutrition, physical activity, body mass index, handgrip strength, testosterone, albumin, sex, adiponectin, total protein, vitamin D, hemoglobin, estradiol, C-reactive protein, glucose, monocytes, and insulin. Handgrip strength measurements and free T3 levels increased linearly between the cluster with the lowest measurements and the cluster withthehighest measurements. The findings of this study may greatly aid in understanding the relationship between blood biomarkers, lifestyle and sarcopenia progression in older adults, and may help indeveloping better prevention and diagnostic strategies as well as more personalized therapeutic interventions.

Respiratory muscle training in people with cervical spinal cord injury - A systematic review.

Spinal cord injury is a physiological disruption often caused by trauma, leading to severe physical and psychological effects, including irreversible impairment and disability. Cervical injuries, particularly between C1 and C8, are the most severe, potentially causing diaphragm paralysis and requiring mechanical ventilation. Reduced respiratory muscle strength not only affects respiratory function but also significantly impacts voice, speech, and communication, which are crucial for quality of life. Conduct a systematic review of the literature on respiratory muscle training protocols in individuals with cervical spinal cord injury and evaluate the methodological quality of scientific publications. Studies were searched by two independent researchers in the Regional Portal of the Virtual Health Library, EMBASE, SCOPUS and PubMed databases, using the descriptors: "respiratory muscle strength", "breathing training", and "cervical spinal cord injury", with no restriction on the time of publication. Studies containing respiratory muscle strength measurements and respiratory muscle training in people with cervical SCI were included and those that associated other techniques with functional respiratory training, such as electrical stimulation and other complementary techniques were excluded. The studies had the methodological quality (internal and external validity) classified by the PEDro scale (Physiotherapy Evidence Database). Nine studies were identified and considered valid based on the inclusion criteria. The protocols presented varied parameters. The session time ranged from 15 to 45 minutes, the number of sessions per day ranged from 1 to 2, the number of days per week ranged from 3 to 7, and the number of intervention weeks ranged from 4 to 10. Only three studies presented internal and external validity for respiratory muscle training programs. This review identified that respiratory muscle training is an effective intervention to improve respiratory function in people with cervical SCI. However, due to the poor methodological quality of the studies, the effect size of the treatment, as well as the ideal dose and intensity, requires further investigation to better determine its overall effectiveness.

Predictive and Cross-Validation Analysis of Aerobic and Anaerobic Performance Based on Maximum Strength

To establish the capacity of absolute maximum strength and relative to body mass (BM) in deadlift (DL) and squat (SQ) exercises to estimate the maximum anaerobic running performance (MART) and maximum aerobic power (VPeak), among individuals stratified into high (HS) vs. low strength score (LS). The sum of workloads (DL+SQ) was also analyzed and cross-validation was tested. Thirty-four students performed five visits in the first phase. In the first three visits the following were performed: sample characterization and consistency analysis of the maximum repetition (RM) for DL and SQ. Participants were stratified based on DL and SQ relativized by BM (DL/BM and SQ/BM). In the last two visits, MART and VPeak were tested. Linear regression for HS participants did not predict MART for all strength measures. In contrast, the regressive model was significant for DL (R2 = 0.482; p = 0.002), DL/BM (R2 = 0.764; p < 0.001), SQ (R2 = 0.357; p = 0.011) and SQ/BM (R2 = 0.644; p < 0.001) in LS participants, compared to MART performance. For VPeak, linear regression also did not demonstrate an association for all strength measures in HS participants. However, SQ (R2 = 0.309; p = 0.021), DL/BM (R2 = 0.343; p = 0.013) and SQ/BM (R2 = 0.618; p < 0.001) were able to predict VPeak. The prediction from the sum of the DL+SQ produced an association for MART (R2 = 0.451; p = 0.003) and VPeak (R2 = 0.273; p = 0.031) in LS participants. In the second phase of the study, 17 participants performed cross-validation by testing the prediction equations. The same methodological procedures were performed for this phase, but only LS participants were tested. The Wilcoxon test compared real MART vs. predicted for DL (p = 0.02) and SQ (p = 0.043), showing differences, but not for DL/BM (p = 0.051) and SQ/BM (p = 0.093). The Wilcoxon test also showed differences for real VPeak vs. predicted for DL/BM (p = 0.002), SQ (p = 0.019) and SQ/BM (p = 0.05). The MART predictive equation based on DL+SQ did not show differences (p = 0.148), but the same did not occur for VPeak based on DL+SQ (p = 0.008). Maximum strength did not show predictive capacity in HS participants. However, it was significant for LS participants. DL showed greater predictive prominence for MART. In contrast, for VPeak, SQ/BM satisfactorily explained the variations in running performance (61%). The predictive equations of MART by DL/BM and SQ/BM were shown to be accurate, as well as DL+SQ to predict MART.

Positive Correlation Between Serum Limonene Levels and Muscle Health in a Representative Adult Population in the United States

Background/Objectives: Monoterpenes, a class of organic compounds with the molecular formula C10H16, have garnered significant attention for their potential medicinal benefits. Emerging evidence suggests they may positively influence skeletal muscle function. However, the impact of monoterpene exposure on muscle strength and mass in humans remains unclear. Methods: To explore this relationship, we analyzed data from 1202 adults (aged ≥ 18 years) who participated in the 2013–2014 National Health and Nutrition Examination Survey (NHANES), focusing on serum levels of three specific monoterpenes—α-pinene, β-pinene, and limonene—and their association with hand grip strength and lean muscle mass. Results: Our analysis revealed that, except for test 2 of hand 1, all grip strength measures showed a positive correlation with ln-limonene levels. The β coefficient for combined grip strength was 2.409 (S.E. = 0.891, p = 0.015). Positive associations were also found between serum limonene levels and lean muscle mass. The β coefficient for the Appendicular Skeletal Muscle Mass Index (ASMI) was 0.138 (S.E. = 0.041, p = 0.004). Furthermore, combined grip strength and ASMI significantly increased across limonene quintiles (p for trend = 0.005 and 0.006, respectively). However, none of the three monoterpene levels showed a significant association with clinically defined low muscle mass or low muscle strength. Conclusions: Our findings suggest a plausible association between exposure to limonene, hand grip strength, and lean muscle mass among adults in the United States. Further investigation is needed to fully understand the underlying mechanisms and medical significance of this association.

Tofersen treatment leads to sustained stabilization of disease in SOD1 ALS in a "real-world" setting.

Patients with amyotrophic lateral sclerosis (ALS) caused by superoxide dismutase 1 (SOD1) gene mutations (SOD1 ALS) treated with tofersen have shown slowing of disease progression, and disease stabilization with recovery of function in some patients. We report our clinical experience with treating patients with SOD1 ALS and the effects of tofersen on outcome measures. This was a single-center observational study of patients with SOD1 ALS receiving treatment with tofersen. The effects of tofersen treatment on neurofilament levels, muscle strength, and clinical outcome measures were assessed. Several patients had outpatient neuromuscular rehabilitation in addition to tofersen treatment and we report changes in functional outcomes. Seven SOD1 ALS patients received treatment at our institution. All patients showed robust and sustained declines in serum NfL and CSF pNFH (mean change serum NfL: -57.9%; mean change CSF pNFH: -67.6%). There was apparent disease stabilization as assessed by the ALSFRS-R total score, mean change 1.1 (SD = 0.7). There was notable improvement in functional independence measured by the FIM motor score, mean change 5.13 points (SD = 3.85). This study provides evidence that tofersen treatment in SOD1 ALS can lead to meaningful preservation of function and suggestions of sustained improvement in neurologic function in some patients, and strongly supports the role of neurofilaments as therapeutic biomarkers.

Strength of low-frequency EEG phase entrainment to external stimuli is associated with fluctuations in the brain's internal state.

The brain attends to environmental rhythms by aligning the phase of internal oscillations. However, the factors underlying fluctuations in the strength of this phase entrainment remain largely unknown. In the present study we examined whether the strength of low-frequency EEG phase entrainment to rhythmic stimulus sequences varied with pupil size and posterior alpha-band power, thought to reflect arousal level and excitability of posterior cortical brain areas, respectively. We recorded pupil size and scalp EEG while participants carried out an intermodal selective attention task, in which they were instructed to attend to a rhythmic sequence of visual or auditory stimuli and ignore the other perceptual modality. As expected, intertrial phase coherence (ITC), a measure of entrainment strength, was larger for the task-relevant than for the task-irrelevant modality. Across the experiment, pupil size and posterior alpha power were strongly linked with each other. Interestingly, ITC tracked both variables: larger pupil size was associated with a selective increase in entrainment to the task-relevant stimulus sequence, whereas larger posterior alpha power was associated with a decrease in phase entrainment to both the task-relevant and task-irrelevant stimulus sequences. Exploratory analyses showed that a temporal relation between ITC and posterior alpha power emerged in the time periods around pupil maxima and pupil minima. These results indicate that endogenous sources contribute distinctly to the fluctuations of EEG phase entrainment.Significance statement Fluctuations in cortical state powerfully shape the perception of external stimuli. Understanding the physiological signatures of cortical state fluctuations is crucial to understand how the brain selectively attends and switches between internal and external content. Here we studied how two signatures of attentional state, pupil-linked arousal and power in the alpha band, shape the entrainment of brain activity to low-frequency rhythmic stimuli. Our results reveal common and dissociable influences of these signatures at slow time scales. Furthermore, measuring and including pupil size and posterior alpha power as covariates in statistical models can help increase statistical power in studies focusing on EEG phase entrainment. Our study provides new evidence on a direct influence of cortical state on the perception of rhythmic stimuli.

Synovial Chondromatosis of the Hand and Wrist: A 35-Year Retrospective Case Review.

Background: Synovial chondromatosis is a condition that rarely occurs in the hand and wrist. Recurrence and malignant transformation are two potential complications of the disease. We set out to retrospectively review 35 years of practice within our sarcoma and tertiary hand unit and identify recurrence or malignant transformation. Methods: This is a retrospective analysis of patients with synovial chondromatosis seen at our sarcoma and tertiary hand unit for the past 35 years. Incidence of recurrence or malignant transformation was noted. Where possible, patients were clinically and radiologically reviewed with range of motion, grip strength and patient evaluation measures obtained. Results: Of 12 patients presenting to the practice, seven patients were followed up and, of these, two demonstrated recurrences. The recurrence was diagnosed based on patient-reported symptoms, clinical examination and the requisition of further imaging. Of the five who could not be followed up, two demonstrated recurrence and one had malignant transformation with a low-grade chondrosarcoma on histology. Conclusions: While a rare disease, we demonstrated recurrence within our small case series. Fusion to obliterate the joint is an option in the management of recurrence. For the diagnostically challenging, genetic testing may be beneficial, though genetic rearrangements are not seen in all cases. All patients should be counselled on symptoms to watch for as a small proportion may experience recurrence and a small percentage may undergo malignant transformation. Level of Evidence: Level IV (Therapeutic).

Observing the Relationship Between Additional Measures of Handgrip Strength and the 6-Minute Push Test in Ambulatory Young Adults

Manual wheelchair users have been shown to have low functional capacity and limited ability to perform activities of daily living. Conventional protocols for assessing physical attributes such as muscle function in this population have unique boundaries such as expensive testing equipment and procedures not specific to wheelchair propulsion. The measurement of muscle function using electronic handgrip dynamometry has shown promise in assessing additional characteristics beyond strength capacity alone. This study aimed to determine the correlations of electronic handgrip dynamometry derived strength, time to peak force generation, fatigability (22.40±10.12%), isometric control, and asymmetry with aerobic capacity in ambulatory young adults. We included 34 recreationally active ambulatory adults aged 23.76±3.57 years. Muscle function was assessed using electronic handgrip dynamometry. Aerobic capacity was examined using the six-minute wheelchair push test (1112.17±92.84ft). Fatigability (22.40±10.12%) showed a significant, near moderate negative correlation (r=-0.345, p<0.05) with push test outcomes, while the correlation with all other measures was not-significant. Our findings show that electronic handgrip dynamometry derived fatigability is related to aerobic capacity in those who use manual wheelchairs. Given the relationships shown in the current study, electronic handgrip dynamometry has promise for assessing functional health in persons with disabilities, which has particular relevance for SCI, and could be used in clinical practice and physical medicine and rehabilitation (PM&R) as a tool to examine functional capacity in applicable populations. However, future research is warranted to assess the concurrent validity of the additional measures of handgrip strength assessing muscle function.

Terahertz thickness measurement based on atomic superheterodyne detection

Terahertz thickness measurement is of great important in materials research and industrial test. And it’s can be applied in materials measurement including wood, paper, ceramics, plastics, and composite materials. Atomic superheterodyne terahertz detector has extremely high sensitivity. The sensitivity of terahertz electric field strength measurement can reach 5.76 μV cm<sup>-1</sup> Hz<sup>-1/2</sup>. Simultaneously, the linear dynamic range is better than 60 dB. So, it can be applied to realize precise thickness measurement of materials through the terahertz transmission efficiency. The experiments in this paper demonstrated the thickness measurement of sapphire crystal and organic materials PTFE. The terahertz signal is shown in Figure A1(a,b). The thickness can be calculated from the transmittance, which is consistent with the result measured directly with a vernier caliper. Furthermore, single-layer graphene and few-layer graphene can be clearly distinguished from terahertz transmission signals, as shown in Figure A1(c). Even for niobium meta thin films with thickness 1 μm, very weak terahertz signal can be well distinguished due to the high sensitivity of atomic superheterodyne terahertz detector. In summary, the technology developed for terahertz thickness measurement based on atomic superheterodyne detection is very important for defect detection, coating check, and parameter measurement of materials.

A pilot trial for efficacy confirmation of 6′-sialyllactose supplementation in GNE myopathy: Randomized, placebo-controlled trial

GNE myopathy is a rare genetic muscle disorder characterized by initial ankle dorsiflexor weakness and the presence of rimmed vacuoles in muscle histopathology. Biallelic mutations in the GNE gene are causative, leading to reduced production of sialic acid. In our previous clinical trial, we used 6′-sialyllactose (6SL) as a supplement to increase sialic acid levels and compared the effects of 6SL at doses of 3 g and 6 g. The findings from the trial revealed superior outcomes in muscle strength, attenuation of muscle degeneration, and bioavailability in the 6 g group.This trial was planned to complement the lack of placebo arm from the previous trial and to provide more conclusive evidence for therapeutic value of 6SL in GNE myopathy. Of the 11 participants, five were allocated to the 6SL and six to the placebo group after undergoing 12 weeks of pre-study observation and stratified randomization. At every visit with an interval of 12 weeks for 48 weeks, all participants underwent muscle strength measurement, muscle MRI, biochemical evaluations, 6-min-walk test, and completed a questionnaire.No safety concerns arose during the trial period. Muscle strength, excluding hand grip power, did not show a significant difference between the two groups, which is attributed to the lack of pronounced muscle strength decline in both groups. Hand grip power tended to decrease in both groups, and this decline was statistically significant in the placebo group (p = 0.0004). The fat fraction measured by MRI showed the most significant results in the posterior thigh. The increase in fat fraction, indicating muscle degeneration, was statistically significant between the two groups (p = 0.0004). Although no statistically significant differences were observed between the groups in anterior thigh and both anterior and posterior lower leg, a trend of slowed increase in fat fraction was noted in the 6SL group compared to the placebo group starting from 24 or 36 weeks. Resialylation of cell surface glycoconjugate was demonstrated in 6SL group by measuring lectin bindings on peripheral blood monocytes.The GNEM-FAS, used to assess patient-reported outcomes, did not show statistical significance in the total score or any of the three domains. However, the tendency for scores in the self-care and upper extremity domains to rebound after 24 weeks in the 6SL group suggests the potential for long-term benefits.The effect of 6SL on muscle strength appeared to be minimal compared to our previous clinical trial, likely due to the short duration of the study and the inclusion of relatively early-stage patients. However, the changes in fat fraction measured by muscle MRI and the results of biochemical assays are more promising, suggesting potential benefits with long-term administration in the future.

Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmonary Rehabilitation.

Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation, airflow limitation, reduced health-related quality of life (HRQL), and exercise intolerance. Pulmonary rehabilitation (PR) is essential for COPD management, but outcomes may be influenced by individual physiological factors. Cardiopulmonary exercise testing (CPET) measures oxygen pulse (O2P), an indicator of stroke volume, yet the impact of baseline O2P on PR effectiveness remains unclear. This retrospective study included 97 participants with COPD who had received PR, of whom 48 were classified as Group 1 (normal O2P) and 49 as Group 2 (low O2P). PR involved 12weeks of hospital-based endurance training on a bike, performed twice a week. Participants were assessed before and after PR using spirometry, respiratory muscle strength measurements, CPET, and HRQL evaluation with the St. George's Respiratory Questionnaire (SGRQ). PR significantly improved exercise capacity (peak work rate and oxygen consumption), dyspnea score, and all domains of the SGRQ, maximum expiratory pressure, ventilatory equivalent, respiratory rate, and mean blood pressure at rest in both groups (p < 0.05). However, improvements in O2P, maximal inspiratory pressure, and tidal volume at rest were observed only in Group 2 but not in Group 1. PR improves exercise capacity, HRQL and specific respiratory function in participants with COPD, regardless of baseline O2P levels. Individuals with lower baseline O2P experience more benefits from PR, including a significant increase in O2P.

The effects of Neurodynamic Mobilization exercises on upper extremity pain, muscle strength, and functions in patients with multiple sclerosis: A randomised controlled, single blinded study.

Manual therapy techniques are available for pain management in Multiple Sclerosis (MS); however, the results of neurodynamic mobilization (NM) are not known. The aim of this study was to investigate the effects of NM exercises on pain, muscle strength and upper extremity functions in MS patients. Patients aged between 18 and 65 years diagnosed with Relapsing Remitting (RR) MS (n = 31) according to McDonald 2010 diagnostic criteria were included in the study. Patients were divided into the NM group (bilateral upper extremity NM and strengthening exercises) (n = 15) and the control group (bilateral strengthening exercises) (n = 16) by simple randomization. Visual Analog Scale (VAS) (most severe and average score) was used to assess pain intensity, and Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire was used to assess pain character. Muscle strength was evaluated with the digital muscle strength measurement device (Kforce Kinvent), manual skills were evaluated with the Nine Hole Peg Test (NHPT) and Manual Ability Measure-36 (MAM-36). Measurements were obtained from the most affected side, unilateral. The mean of the most severe score of VAS (p < 0.001), the average score of VAS (p < 0.001), and the LANSS in both groups (p < 0.05) decreased significantly. Shoulder flexor muscle strength was increased significantly in both groups (p < 0.05). Shoulder extensors, elbow flexors, and elbow extensors was increased significantly in NM group (p < 0.05). MAM-36 scores was increased significanty in both groups (p < 0.05). NHPT scores showed significant decrease in the NM group (p < 0.05). There was no significant difference between the groups in terms of VAS, LANSS, muscle strength, MAM-36 and NHPT (p > 0.05). It was found that NM exercises added to upper extremity strengthening therapy in patients with MS reduced pain, increased muscle strength of shoulder extensors, elbow flexors, and elbow extensors, and improved manual dexterity. However, although positive effects were observed when NM exercises were added to the strengthening exercises, the results were found to be similar in these groups.

Evaluation of Recycled Steel Fiber Effect on Concrete Performance Using Artificial Intelligence Technique

Reusing waste materials is critical for sustainability and preventing adverse impacts on human life and the environment. Waste vehicle tires have become a big problem due to high consumption. It is possible to separate waste tires into different materials through technological means. Recycled steel fiber is a material obtained from these tires, and various studies have been conducted on its use in concrete. In addition to the geometric properties, such as the length and diameter, the percentage of steel fiber also affects the strength of concrete. In this study, the effect of recycled steel fiber on concrete's compressive and flexural strength values was estimated using artificial intelligence functions with high statistical significance. The relationship between the strength results and the recycled steel fiber properties was determined using literature data. The model's accuracy was demonstrated by comparing the obtained compressive and flexural strengths with the laboratory results. Thanks to the model with a high correlation coefficient created as a result of the study, the effect of recycled steel fiber on concrete performance as an alternative to laborious laboratory tests can be predicted with artificial intelligence-supported functions. With the proposed neural network method, R2 values of 0.83 for compressive strength measurements and 0.96 for flexural strength measurements were obtained. Based on the findings, it is concluded that the recycled steel fiber-reinforced concrete parameters can be well represented by artificial neural networks, and the presented model can be used as a good alternative to laboratory studies for further research.

Effects of Intensive Impairment-Oriented Arm Rehabilitation for Chronic Stroke Survivors: An Observational Cohort Study.

Objective: To assess the effects of a two-week course of intensive impairment-oriented arm rehabilitation for chronic stroke survivors on motor function. Methods: An observational cohort study that enrolled chronic stroke survivors (≥6 months after stroke) with mild to severe arm paresis, who received a two-week course of impairment-oriented and technology-supported arm rehabilitation (1:1 participant-therapist setting), which was carried out daily (five days a week) for four hours. The outcome measures were as follows: the primary outcome was the arm motor function of the affected arm (mild paresis: BBT, NHPT; severe paresis: Fugl-Meyer arm motor score). The secondary outcomes were measures of finger strength, active ROM, spasticity, joint mobility/pain, somatosensation, emotional distress, quality of life, acceptability, and adverse events. Results: One hundred chronic stroke survivors (≥6 months after stroke) with mild to severe arm paresis were recruited. The training was acceptable (drop-out rate 3%; 3/100). The clinical assessment indicated improved motor function (SMD 0.42, 95% CI 0.36-0.49; n = 97), reduced spasticity/resistance to passive movement, and slightly improved joint mobility/pain and somatosensation. The technology-based objective measures corroborated the improved active range of motion for arm and finger joints, reduced finger spasticity/resistance to passive movement, and the increased amount of use in daily life, but there was no effect on finger strength. The patient's emotional well-being and quality of life were positively influenced. Adverse events were reported by the majority of participants (51%, 49/97) and were mild. Conclusions: Structured intensive impairment-oriented and technology-supported arm rehabilitation can promote motor function among chronic stroke survivors with mild to severe arm paresis and is an acceptable and tolerable form of treatment when supervised and adjusted by therapists.

Impact of Handgrip Strength on Survival in Hemodialysis Patients

Background: Hemodialysis patients face a high mortality risk, requiring effective clinical assessments. In these patients, muscle wasting due to protein-energy wasting (PEW) leads to increased frailty, which is strongly associated with worse outcomes, including higher mortality. As muscle mass declines, so does functional capacity, making regular assessment of both muscle mass and function critical for prognostic evaluation. Handgrip strength (HGS) offers a quick and reliable measure of muscle strength and functional capacity. In this study, we focused on the impact of HGS on survival in hemodialysis patients, analyzing its relationship with muscle mass and BMI. Methods: This retrospective cohort study included 408 dialysis patients (221 males, 187 females) who underwent bioimpedance spectroscopy (BIS) and HGS assessments between March 2021 and August 2023. Data collected included BIS profiles, HGS, dialysis status, age, complete blood count, blood chemistry, mortality, and CONUT scores. Results: Cox proportional hazards regression analysis revealed that lean tissue index (LTI) (HR 3.30, 95% CI 1.75–6.19), body mass index (BMI) (HR 2.65, 95% CI 1.17–6.01), and handgrip strength (HGS) (HR 4.22, 95% CI 2.05–8.70) were significant predictors of survival in the overall dialysis patient cohort. Gender-specific analysis showed that in males, both LTI (HR 4.81, 95% CI 1.89–12.23) and HGS (HR 5.45, 95% CI 2.18–13.61) significantly predicted survival. In females, HGS (HR 6.01, 95% CI 2.42–14.94) was a significant predictor, while LTI was also significant (HR 3.22, 95% CI 1.24–8.40, p = 0.017). In the multivariate Cox proportional hazards analysis, which adjusted for age, diabetes mellitus (DM), hypertension (HTN), BMI, fat tissue index (FTI), LTI, serum albumin, C-reactive protein (CRP), and CONUT score, HGS remained a significant predictor of survival in female dialysis patients (HR 2.77, 95% CI 1.00–7.65, p = 0.049). Conclusions: HGS has been identified as an important factor for survival in dialysis patients, particularly in female patients, independent of muscle mass and BMI.

Development and Characterization of Bioplastics from Straw and Rice Husk for: Effect of Addition of Glycerin, CMC, and TiO2

The development of environmentally friendly materials is crucial to mitigate the environmental impact of conventional plastics. This study focuses on developing bioplastics using rice straw and rice husks, combined with glycerine, carboxymethyl cellulose (CMC), and titanium dioxide (TiO₂). Glycerine acts as a plasticizer to enhance flexibility, CMC functions as a matrix binder, and TiO₂ serves as a reinforcing agent to improve mechanical strength. Bioplastics were produced using the casting method with specific proportions of these materials. Characterization tests included scanning electron microscopy (SEM) for morphology, biodegradability tests, water absorption analysis, and tensile strength measurements. Results revealed that the combination of rice straw and rice husks produced bioplastics with varied morphologies. TiO₂ enhanced mechanical strength and material homogeneity, though its distribution requires further optimization. Glycerine significantly increased flexibility, while CMC improved matrix cohesion. The novelty of this research lies in the integration of agro-industrial waste—rice straw and rice husks—with TiO₂, glycerine, and CMC, creating bioplastics that balance biodegradability, mechanical properties, and flexibility. This innovative approach demonstrates the potential of utilizing agricultural byproducts to produce sustainable alternatives to conventional plastics, offering customizable properties for diverse applications.

Effects of Rain Particles on the Strength of the Electromagnetic

This report presents results from scattering and absorption by rain effects on the strength of the microwave signal at the X-band. The measurements of the signal strength are done by measuring the S12 parameters in different weather conditions: No rain, shower rain, and heavy including the wind effects. The measurement is done inside an artificial rain setup. The measurements are compared to their identical based simulations using CST MWS. The results are also quantitatively compared with results from Rayleigh theory that was reported in the literature.

Interpositional Bioresorbable Scaffold-Anchor Appears Non-inferior to a Standard Anchor in the Treatment of Rotator Cuff Tears.

Failure after rotator cuff repair is typically due to a loss of integrity of the bone-tendon interface. The BioWick anchor (Zimmer-Biomet) is an interpositional scaffold-anchor that was developed to improve tendon-bone healing. The purpose of this study was to determine the clinical efficacy of this novel anchor compared with a standard anchor with respect to retear rates and patient outcomes. We enrolled 99 patients in a double-anonymized, prospective, randomized controlled trial who underwent rotator cuff repair. Fifty patients were randomized to the novel anchor group and 49 patients were randomized to the standard anchor group. The primary outcome was rotator cuff repair integrity assessed via ultrasound at 6 months postoperatively. Secondary outcomes included visual analog scale (VAS) pain score, American Shoulder and Elbow Surgeons (ASES) score, Simple Shoulder Test (SST), strength, and active range of motion (AROM) assessed preoperatively and postoperatively at 3 and 6 months. There were no statistically significant differences in demographic data, mean rotator cuff tear size, tobacco use, workers' compensation status, or operative side between the groups. At 6-month follow-up, the retear rate was 22% (n=9) for the novel anchor group vs 23% (n=10) for the standard anchor group (P=.8864). Secondary outcomes, including VAS pain score, ASES score, SST, strength, and AROM measurements, did not differ significantly between the groups at 3- or 6-month follow-up. There were no complications identified in either group. This study did not demonstrate superior clinical improvements or decreased retear rates with the use of this novel anchor compared with a standard anchor. [Orthopedics. 202x;4x(x):xx-xx.].

Sub-Alfvénic Turbulence: Magnetic-to-kinetic Energy Ratio, Modification of Weak Cascade, and Implications for Magnetic Field Strength Measurements

We study the properties of sub-Alfvénic magnetohydrodynamic (MHD) turbulence, i.e., turbulence with Alfvén mach number M A = V L /V A < 1, where V L is the velocity at the injection scale and V A is the Alfvén velocity. We demonstrate that MHD turbulence can have different properties, depending on whether it is driven by velocity or magnetic fluctuations. If the turbulence is driven by isotropic bulk forces acting upon the fluid, i.e., is velocity driven, in an incompressible conducting fluid we predict that the kinetic energy is MA−2 times larger than the energy of magnetic fluctuations. This effect arises from the long parallel wavelength tail of the forcing, which excites modes with k ∥/k ⊥ < M A. We also predict that as the MHD turbulent cascade reaches the strong regime, the energy of slow modes exceeds the energy of Alfvén modes by a factor MA−1 . These effects are absent if the turbulence is driven through magnetic fluctuations at the injection scale. We confirm our predictions with numerical simulations. Since the assumption of magnetic and kinetic energy equipartition is at the core of the Davis–Chandrasekhar–Fermi (DCF) approach to measuring magnetic field strength in sub-Alfvénic turbulence, we conclude that the DCF technique is not universally applicable. In particular, we suggest that the dynamical excitation of long azimuthal wavelength modes in the galactic disk may compromise the use of the DCF technique. We discuss alternative expressions that can be used to obtain magnetic field strength from observations and consider ways of distinguishing the cases of velocity and magnetically driven turbulence using observational data.

Nutritional Status, Frailty, Oral Health, and Oral Motor Functions in Long-Term Care Residents with Swallowing Dysfunction.

Background: Swallowing dysfunction is a prevalent but often overlooked problem in long-term care facilities. This study investigated the relationships between nutritional deficits, frailty, oral health, and swallowing dysfunction. Additionally, we explored the associations between oral muscle weakness, frailty markers, and swallowing dysfunction. Methods: We recruited 373 participants from seven long-term care facilities across Taiwan. Swallowing function, frailty, nutrition status, and oral health were assessed by research staff. Oral muscle function was evaluated through tongue strength measurements, cheek bulging function tests, the Repetitive Saliva Swallowing Test (RSST), and a diadochokinetic task. Frailty was assessed through grip strength as well as mid-upper arm and calf circumference measurements. Results: The Functional Oral Intake Scale revealed that 97 participants (26%) had swallowing dysfunction. Participants with swallowing dysfunction had poorer nutritional status, higher frailty levels, and worsened oral health. Frailty was the factor most strongly associated with swallowing dysfunction. Participants with swallowing dysfunction also exhibited lower tongue pressure, decreased cheek-bulging ability, fewer repetitions in the diadochokinetic task, lower scores on the RSST, lower calf circumferences, and lower grip strength. Logistic regression demonstrated that cheek bulging was most strongly associated with swallowing dysfunction. Furthermore, lower grip strength was significantly associated with swallowing dysfunction. Conclusions: Frailty was most strongly associated with swallowing dysfunction, followed by poorer nutritional status and worsened oral health. These factors should be thoroughly assessed in long-term care residents. Participants with swallowing dysfunction also experienced oral muscle weakness, particularly in cheek bulging. Grip strength, which represents frailty, was directly associated with swallowing dysfunction and could serve as a crucial indicator of swallowing dysfunction.