Measurement Of Frequency Shift Research Articles

Flexible surface plasmon based coupled triple band UHF-microwave sensor for glucose sensing application

Although the correlation between a glucose concentration and its permittivity is somewhat weak to be measured, the glucose concentration is a strong function of the dispersion. In terahertz or microwave frequencies, dispersion can be observed or measured along the interface between an object under test and a metamaterial or surface plasmonic surface, which is basically a metal structure characterized by periodically arrayed holes, grooves, or metal grating. In this work, we have focused on the method for improving the accuracy of a glucose measurement by proposing a new triple-band microwave sensor design and by measuring the resonant frequency shift associated with a glucose concentration at three frequencies simultaneously. A new triple-band glucose sensor of dimension (30 mm x 10 mm) was designed with the main sensing region as compact as 14 mm with two conducting microstrip lines on both ends of the sensor. The sensor design has been realized on a thin flexible substrate of 0.15 mm thickness. The proposed sensor has been designed to measure glucose concentration through the measurement of a resonant frequency shift at 650 MHz, 4.45 GHz, and 10.35 GHz. Overall, the glucose concentration has been found to be correlated positively and linearly with the resonant frequency shift at these frequencies.

Measurement and advanced data post-processing of proton resonance frequency shift in 7 T MRI to obtain local temperature in a tissue-mimicking phantom

Abstract The radio-frequency (RF) transmit power deposition in tissue during magnetic resonance imaging (MRI) at ultra-high fields, i.e. B 0 ≥ 7 T, is a major challenge for pulse sequences requesting large flip angles. The absorbed RF energy can pose safety risk to patients as it is rising temperature in the tissue. The temperature can be accessed using MRI itself via the proton-resonance frequency (PRF) shift technique, which at low B 0 has been shown a valid MR thermometry method. In this paper, we explore the applicability of the PRF method to the assessment of local temperature in 7 T MRI procedures. To this end, we built a phantom filled with a material presenting electrical conductivity and permittivity close to muscle tissue. Tubes filled with oil were placed nearby the phantom to observe the time dependent B 0 drift. MRI phase images were acquired by gradient-echo (GRE) sequences at time points between spin-echo sequences with large flip angle allowing for a continuous assessment of the temperature during a 114 min RF-heating experiment. All acquired phase images were post-processed with attention to the time dependent instability of B 0, and, in addition, to potential spatial and temporal phase discontinuities, known as wraps. In this paper, we present a strategy to analyze and to unfold these phase wraps for large measurement fields and long acquisition times. It is shown that the PRF shift method is beneficial for the assessment of temperature at 7 T MRI. The temperature maps for axial and coronal planes display a temperature increase of approximately 3.5 °C during the time of the RF-heating experiment. Overall it is shown that B 0-drift correction and, importantly, the spatio-temporal unwrapping are an indispensable part of post-processing.

Effects of low-dose gamma radiation on DNA measured using a quartz tuning fork sensor

Despite the expected direct effects of radiation on DNA through its direct interaction with the biomolecule, research indicates that radiation also interacts with the DNA’s environment, resulting in indirect effects. Therefore, in this study, we explored the feasibility of using the quartz tuning fork (QTF) sensor system in biomedical applications, specifically in detecting DNA damage caused by low doses of gamma radiation, directly and indirectly. We differentiated between direct and indirect damage by analyzing the fork’s resonance frequency changes. This experiment was divided into three stages: before, during, and after irradiation. Each stage involved samples of pure DNA and DNA in a 60-µL aqueous solution, evaluated under identical conditions. Before irradiation, we measured frequency shifts (Δf) over a 20-min period, resulting in values of 19.34, 20.25, and 7.6 Hz for water, DNA, and DNA in water, respectively. Subsequently, the samples were irradiated with cesium-137 for the specified duration, resulting in frequency shifts of ∼ 39.21, 28.37, and 41.23 Hz for the same conditions. Our investigations showed an increase in Δf from 20.25 to 28.3 Hz at doses ranging from 7.5 to 30 µGy for pure DNA. Interestingly, DNA in aqueous solution exhibited hypersensitivity to radiation, with frequency shifts ranging from 7.6 to 41.23 Hz. Furthermore, we observed a significant difference in frequency shift after irradiation between pure DNA and DNA in water, with shifts of ∼ 70.75–98.45 Hz and 56.32–79.28 Hz for DNA and DNA in water, respectively. This result indicates a significant increase in DNA damage in aqueous environments, driven by the generation of active hydroxyl radicals (OH−), resulting in base damage and an associated increase in strand breaks. Consequently, our research indicates a lack of substantial direct impact on DNA repair owing to the absence of a conducive postirradiation environment. Therefore, QTF is a valuable biomarker for radiation sensitivity and is promising for future applications as a mass-sensitive biosensor.

Determination of the vector velocity of artificial ionospheric irregularities based on Doppler measurements by the bi-static scatter method of HF radio signals propagating over long radio paths

During experiments on the modification of the high-latitude ionosphere by high-power HF radio waves of ordinary or extraordinary polarization of the EISCAT/Heating facility (Tromsø, Norway) in 2013, 2016, and 2019, Doppler measurements of diagnostic HF radio signals over long radio paths were carried out by the bistatic scatter method. We studied characteristics of Doppler frequency variations in bistatic scattered radio signals, using the experimental results obtained along radio paths of different lengths (up to ~8500 km) and orientation. We examined numerical dependences of the Doppler frequency variations in a radio signal on the azimuth of the wave vector of a radio wave incident onto an artificially disturbed region, on the bistatic scattering angle, and on the azimuthal direction of irregularity motion in an artificially disturbed region of the ionosphere. From simultaneous measurements of the Doppler frequency fD of the radio signal along two diagnostic radio paths, we numerically estimated the velocity vector of irregularities in the artificially disturbed region of the ionosphere. The total vector velocity of artificial ionospheric irregularities can be calculated from measurements of the Doppler frequency shift along several long diagnostic radio paths after preliminary analysis of experimental observations with the results of trajectory modeling of diagnostic HF radio signals.

Определение вектора скорости искусственных ионосферных неоднородностей по данным доплеровских измерений методом ракурсного рассеяния КВ радиосигналов, распространяющихся на протяженных радиотрассах

During experiments on the modification of the high-latitude ionosphere by high-power HF radio waves of ordinary or extraordinary polarization of the EISCAT/Heating facility (Tromsø, Norway) in 2013, 2016, and 2019, Doppler measurements of diagnostic HF radio signals over long radio paths were carried out by the bistatic scatter method. We studied characteristics of Doppler frequency variations in bistatic scattered radio signals, using the experimental results obtained along radio paths of different lengths (up to ~8500 km) and orientation. We examined numerical dependences of the Doppler frequency variations in a radio signal on the azimuth of the wave vector of a radio wave incident onto an artificially disturbed region, on the bistatic scattering angle, and on the azimuthal direction of irregularity motion in an artificially disturbed region of the ionosphere. From simultaneous measurements of the Doppler frequency fD of the radio signal along two diagnostic radio paths, we numerically estimated the velocity vector of irregularities in the artificially disturbed region of the ionosphere. The total vector velocity of artificial ionospheric irregularities can be calculated from measurements of the Doppler frequency shift along several long diagnostic radio paths after preliminary analysis of experimental observations with the results of trajectory modeling of diagnostic HF radio signals.

Unraveling the nature of sensing in electrostatic MEMS gas sensors

This paper investigates the fundamental sensing mechanism of electrostatic MEMS gas sensors. It compares among the responsivities of a set of MEMS isopropanol sensors before and after functionalization, and in the presence and absence of electrostatic fields when operated in static and dynamic detection modes. In the static mode, we found that the sensors do not exhibit a measurable change in displacement due to added mass. On the other hand, bare sensors showed a clear change in displacement in response to isopropanol vapor. In the dynamic mode, functionalized sensors showed a measurable frequency shift due to the added mass of isopropanol vapor. In the presence of strong electrostatic fields, the measured frequency shift was found to be threefold larger than that in their absence in response to the same concentration of isopropanol vapor. The enhanced responsivity of dynamic detection allows the sensors to measure the vapor mass captured by the functional material, which is not the case for static detection. The detection of isopropanol by bare sensors in static mode shows that change in the medium permittivity is the primary sensing mechanism. The enhanced responsivity of dynamic mode sensors when operated in strong electrostatic fields shows that their sensing mechanism is a combination of a weaker added mass effect and a stronger permittivity effect. These findings show that electrostatic MEMS gas sensors are independent of the direction of the gravitational field and are, thus, robust to changes in alignment. It is erroneous to refer to them as ‘gravimetric’ sensors.

Design, analysis and validation of a microstrip patch antenna with enhanced coupling for leaf moisture sensing: an IoT approach

An innovative IoT-based system utilizing a modified slotted microstrip patch antenna with enhanced coupling is presented for precise measurement of leaf moisture content. The antenna employs a rectangular slot above the feed point with an advanced coupling technique to enhance sensitivity. The antenna, fabricated on a 0.8 mm F4B substrate, is designed to resonate within the 2.40 to 3.0 GHz range under unloaded conditions. A parametric analysis focusing on leaf permittivity ranging from 20 to 30 is conducted to determine the antennas’ sensitivity. Experimental measurements of the reflection coefficient (S11) with respect to resonant frequency shift are performed with leaf samples as the samples under test (SUT). Experimental results reveal that the proposed patch antenna’s sensitivity is significantly enhanced, ranging from 0.57 to 1.67 times greater than that of traditional patch antennas for the five leaf samples tested. The antenna exhibits a sensitivity of 0.06 GHz and 0.02 GHz for the modified and enhanced coupling designs, respectively. The mean relative error between predicted and measured moisture content values is low at 0.038. The findings highlight the antenna’s increased sensitivity in detecting leaf moisture content and illustrate the potential of the proposed IoT-based system for real-time agricultural monitoring, marking an advancement in precision farming practices. The study validates the microstrip patch antenna’s capability as a moisture sensor through detailed sensitivity analysis, frequency shift measurements, and regression modeling.

Brillouin frequency shift measurement by zero-crossing point search in virtually synthesized spectra of Brillouin gain and loss

We demonstrate a method for fast and precise Brillouin frequency shift measurement based on searching for the zero-crossing point of a virtually composed spectrum of Brillouin gain and loss obtained by a dual-frequency probe beam. Simulations and experiments show that searching for the zero-crossing point of a virtually synthesized Brillouin gain spectrum can be easily done without a large error compared with peak search of the Brillouin gain spectrum in the conventional method.

Simple DFS and AOA simultaneous measurement scheme without directional ambiguity with co-frequency self-interference signal cancellation

A photonic method based on a dual-polarization dual-parallel Mach–Zehnder modulator (DPol-DPMZM) for the simultaneous measurement of the Doppler frequency shift (DFS) and angle of arrival (AOA) of microwave signals is proposed and demonstrated by simulation. The upper arm of each sub-DPMZM is driven by the echo and self-interference signals from the antenna, while the lower arm is driven by the reference signal 1 and reference signal 2. The phase and amplitude of the reference signal 1 are adjusted to match the interference signals for achieving the self-interference cancellation (SIC). At the central office (CO), the DFS and AOA can be acquired in real time without directional ambiguity by processing the two downconverted low-frequency tones in the photocurrent. The simulation results show that the presence of the SI signal will seriously interfere with the observation of the SOI frequency and waveform, and the self-interference cancellation depth of about 42 dB can be obtained after the SIC. The measurement errors of the DFS without direction ambiguity are within 0.2 Hz. After the Hilbert transformation of the intermediate frequency (IF) signal, the AOA can be measured from −87.31∘ to +87.31∘ with errors less than 3.9°. The system has a large bandwidth, excellent real-time performance, and better invisibility, and is expected to be used in modern electronic warfare systems.

High resolution frequency shift measurement based on the time domain mode-locked optoelectronic oscillator

High resolution frequency shift measurement based on the time domain mode-locked optoelectronic oscillator

Molecularly Imprinted Chitosan Modified Quartz Tuning Fork Sensors for Real Time Biosensing in Liquid Environment

Several new sensing technologies have emerged to meet the escalating demand for accurate and rapid diagnosis. We present an overview of the development of highly sensitive and selective Quartz Tuning Fork (QTF)-based sensors in a liquid environment, which will be critically important for contemporary diagnostic methods reliant on sensing technologies. The purpose of this study is to modify QTF prongs using molecularly imprinted chitosan, in combination with the operation of a quartz tuning fork as a piezoelectric crystal for biomedical applications. Through real-time data acquisition, we evaluate QTF resonance frequency shifts in dry and liquid environments using a model protein, BSA. As a result, the QTF-based sensor fails to detect BSA in dry conditions. It is however possible to measure frequency shifts ranging from 5 to 25 µg /mL within a liquid matrix. There is a rapid equilibration response time of 2 to 10 minutes depending on the concentration of BSA in the sensor. With the developed QTF-based sensor, a sensitivity of 1.1069 Hz/ µg has been achieved within the liquid matrix. As a result of the excellent properties of molecularly imprinted chitosan, it has been possible to develop a QTF-based biosensor capable of acquiring real-time data even when it is in liquid solutions.

Microwave Photonic Mixing Approach to Doppler Frequency Shift Measurement

Microwave Photonic Mixing Approach to Doppler Frequency Shift Measurement

Quantifying the Nearly Random Microheterogeneity of Aqueous tert-Butyl Alcohol Solutions Using Vibrational Spectroscopy.

The microheterogeneous structure of aqueous tert-butyl alcohol (TBA) solutions is quantified by combining experimental, simulations, and theoretical results. Experimental Raman multivariate curve resolution (Raman-MCR) C-H frequency shift measurements are compared with predictions obtained using combined quantum mechanical and effective fragment potential (QM/EFP) calculations, as well as with molecular dynamics (MD), random mixture (RM), and finite lattice (FL) predictions. The results indicate that the microheterogeneous aggregation in aqueous TBA solutions is slightly less than that predicted by MD simulations performed using either CHARMM generalized force field (CGenFF) or optimized parameters for liquid simulations all atom (OPLS-AA) force fields but slightly more than that in a self-avoiding RM of TBA-like molecules. The results imply that the onset of microheterogeneity in aqueous solutions occurs when solute contact free energies are about an order of magnitude smaller than thermal fluctuations, thus suggesting a fundamental bound of relevance to biological self-assembly.

Improving BFS measurement accuracy of BOTDR based on Cauchy proximal splitting

A novel approach based on the Cauchy proximal splitting (CPS) algorithm is proposed to improve Brillouin frequency shift (BFS) measurement accuracy in Brillouin optical time domain reflectometry system. The CPS algorithm utilizes proximal splitting to handle the data and the penalty function based on Cauchy distribution to accurately estimate the target signal to promote sparsity, achieving significant improvement in signal-to-noise ratio (SNR). Experimental results confirm that with a SNR increase of 12.7 dB, an increase in BFS measurement accuracy from 4.78 MHz to 0.43 MHz is achieved over a 10.3 km sensing fiber. The denoising effects of the CPS, wavelet denoising (WD) and non-local mean (NLM) algorithms are further compared, demonstrating that the CPS algorithm has the lowest root mean square error (0.43 MHz) and no deterioration in spatial resolution rather than the WD and NLM algorithms does.

Frequency tunable coherent perfect absorption and lasing in radio-frequency system for ultrahigh-sensitive sensing

A coherent perfect absorption-lasing (CPAL) point in non-Hermitian physics systems has infinite output amplitudes (or quality factor) theoretically and has been utilized for applications. However, practical implementation of CPAL systems faces extreme challenges because of the deviations of electronic components from ideal values, which makes it difficult to attain the CPAL state. Moreover, the amplitude-based output is easily interfered by noises or environments and is inferior as compared to frequency shift-based sensing. Through the investigation of the effects of component deviations on general CPAL systems, we propose an eigenstate tuning method specifically tailored for radio-frequency (RF) CPAL systems. The method enables the realization of CPAL states at any desired frequency with dynamic ranges of signal amplitudes exceeding 60 dB experimentally or to work at a frequency shift-based sensing. Then, a CPAL-based RF sensor system is developed for verification, showing an ultrahigh sensitivity of 1.9 dB/10 fF by measuring output coefficient variation or 9.4 MHz/pF by measuring frequency shift, significantly broadening the application scope of CPAL systems.

Precision Doppler shift measurements with a frequency comb calibrated laser heterodyne radiometer.

We report precision atmospheric spectroscopy of CO2 using a laser heterodyne radiometer (LHR) calibrated with an optical frequency comb. Using the comb calibrated LHR, we record spectra of atmospheric CO2 near 1572.33 nm with a spectral resolution of 200 MHz, using sunlight as a light source. The measured CO2 spectra exhibit frequency shifts by approximately 11 MHz over the course of the 5-h measurement, and we show that these shifts are caused by Doppler effects due to wind along the spectrometer line of sight. The measured frequency shifts are in excellent agreement with an atmospheric model, and we show that our measurements track the wind-induced Doppler shifts with a relative frequency precision of 2 MHz (3 m·s-1) for a single 10 s measurement, improving to 100 kHz (15 cm·s-1) after averaging (equivalent to a fractional precision of a few parts in 1010). These results demonstrate that frequency comb calibrated LHR enables precision velocimetry that can be of use in applications ranging from climate science to astronomy.

Single-channel system for joint unambiguous measurement of DFS and AOA based on serrodyne modulation.

In this paper, a photonic-assisted system for simultaneous and unambiguous measurement of the Doppler frequency shift (DFS) and angle-of-arrival (AOA) using a dual-parallel dual-drive Mach-Zehnder modulator (DP-DDMZM) is proposed and investigated. The echo signals received by two receiving antennas are applied to the radio frequency ports of one sub-DDMZM of the DP-DDMZM. The bias port of the sub-DDMZM is fed by a binary electrical signal that is used to construct two different mapping curves on the relationship between the phase difference and the power of the output intermediate frequency (IF) signal. Therefore, unambiguous AOA measurement with extended range can be realized. The transmitted signal is input into the other sub-DDMZM to implement single-sideband modulation, which is then frequency shifted based on serrodyne modulation. Both the value and direction of DFS can be derived intuitively from the frequency of the output IF signal. Simulation results show that the measurement error of unambiguous DFS measurement is no more than ±0.008H z in the range of -100k H z to 100kHz, and the measurement error of unambiguous AOA is less than ±0.2∘ in the range of -70.8∘ to 70.8°. Moreover, since the scheme does not involve the construction of multi-channels or use of any filter or polarization dependent device, the system has concise structure, high accuracy, large operating bandwidth, and strong robustness, and can be considered as a very promising solution for actual applications.

Scanning-free hybrid Rayleigh-Brillouin distributed fiber-optic sensing system.

Hybrid systems based on Brillouin optical time domain analysis (BOTDA) utilizing Rayleigh backscattering light wave as a probe have enabled single-end and long-range distributed sensing for multiple parameters. However, the spatial resolution for dynamic parameter measurement is limited, and the frequency scanning process of BOTDA is time-consuming. To address these challenges, we propose a hybrid system that combines BOTDA and time-gated digital optical frequency domain reflectometry (TGD-OFDR), aiming to enhance the spatial resolution of dynamic measurements without compromising the system's signal-to-noise ratio and eliminate the frequency scanning process of BOTDA. In the experimental setup, we conducted measurements on a 9.52 km single-mode fiber. A sinusoidal vibration with a frequency of 3 kHz was measured with a spatial resolution of 3 m, achieving a noise floor of 0.05 nε/√Hz. Furthermore, temperature measurements with a spatial resolution of 10 m and a Brillouin frequency shift (BFS) measurement accuracy of 0.74 MHz were successfully obtained using the scanning-free single-end BOTDA technique. This hybrid system shows promising potential for various applications in distributed fiber-optic sensing.

Fetal pulmonary artery stiffness is a strong predictor of persistent pulmonary hypertension of the newborn - An echocardiographic study

ObjectivePulmonary artery stiffness (PAS) is a strong and independent predictor of mortality in adult patients with pulmonary hypertension (PH). But the change in PAS during perinatal period remains unknown. Here, we aimed to explore the feasibility and performance of PAS on predicting persistent pulmonary hypertension of the newborn (PPHN). Methods1325 fetuses underwent a dedicated echocardiography screening for fetal heart defects during second trimester, third-trimester and neonatal period with the measurement of acceleration time (PAAT) and maximal frequency shift (MFS) of pulmonary artery flow. PAS (MFS/PAAT ratio) was calculated. ResultsSix fetuses were diagnosed as PPHN. Compared with the normal fetuses, those with PH had greater values of PAS during each period of time (second trimester, 52.6(46.2–54.5) vs. 32.4(28.0–39.4) kHz/s, p = 0.0003; third trimester, 52.9(46.1–55.3) vs. 29.7(27.3–33.3) kHz/s, p = 0.0002; neonatal period, 127.4(85.2–150.8) vs. 26.6(22.7–35.0) kHz/s, p < 0.0001). There was a statistically significant correlation between PAS and mean pulmonary artery pressure (p < 0.05) but no correlation between PAS and gestational age (p > 0.05) whether in normal fetuses or not. The area under receiver operating characteristic curve (AUC) of 0.97 for PAS during third trimester was superior to that for PAS during second trimester (AUC, 0.94) in predicting PPHN. The optimal cutoff value of PAS during third trimester was 37.40 KHz/s, with a sensitivity of 100%, a specificity of 91%, and an accuracy of 92%. ConclusionThere was a significant difference in PAS between normal fetuses and those with PH. PAS has a power performance on predicting PPHN.

Determination of Meteor Vector Velocity Using MU Interferometry Measurements of Head Echoes

A new method for measuring the vector velocity of meteoroids using meteor head echoes is proposed in this study. The lateral velocity is determined by utilizing the phase interference measurement between channels, while the radial velocity is obtained using a conventional Doppler frequency shift measurement. Compared to previous studies, this method does not require multi-site observations and can calculate the vector velocity of meteors in real-time. This paper provides the complete process for the inversion of the meteor vector velocity, detailing the analyzing process using MU radar head echo data. First, the MUSIC algorithm was used to estimate the DOA of the meteor target, which is a parameter required for lateral velocity measurement. Channel calibration is required before this estimation. Next, delay-Doppler matched filter processing was performed on each receiving channel’s data to determine the distance and radial velocity of the meteor target. Subsequently, the lateral velocity component was synthesized using the least squares method from the phase difference rate extracted from the matched filter output results of multiple channel pairs. Then, the vector velocity and trajectory of the meteor could be determined. The method was verified using MU radar head echo data. Different groups of channel pairs were selected for calculating the lateral velocity, and the results were found to be close, demonstrating the self-consistency of the method. Additionally, the calculated vector velocity is consistent with the direction and magnitude of the meteor’s motion trajectory, confirming the feasibility of the proposed approach. The method allows for the observation of more prominent characteristics of meteoroid motion, providing a more detailed observation capability of velocity variations in other directions than previous methods.