Measure Of Inhibitory Control Research Articles

Improving Everyday Functioning in the Old-Old with Working Memory Training

The aim of this study was to assess gains related to working memory (WM) training, in the short and long term (9 months after the training), in abilities required in everyday life, and in cognitive measures in old-old adults (aged ≥ 75 years). Thirty-two community-dwelling older adults (aged 75-85 years) were randomly assigned to a training or an active control group. In addition to testing for any specific gains in a WM task similar to the one used in the training (criterion task), we sought transfer effects to: 1) abilities involved in everyday life using objective performance-based tasks (the Everyday Problem Test [EPT] and the Timed Instrumental Activities of Daily Living [TIADL] scale; 2) tasks demanding the comprehension and recall of spatial information and pairing names with faces; and 3) a measure of inhibitory control, that is, recall errors (intrusion errors). Only the trained group showed specific gains in the criterion task, and in the TIADL in the short term. At follow-up, the trained group maintained gains in the criterion task, and showed transfer effects to everyday problem-solving (in the EPT), and in constructing spatial representations of an environment. The trained group also improved in a cognitive inhibition measure (intrusion errors) at follow-up. No such improvements were seen in the active control group. WM training may be a valid way to help old-old adults preserve at least some abilities related to everyday functioning.

Cognitive Measures and Performance on the Antisaccade Eye Movement Task.

The antisaccade (AS) task is considered a prominent measure of inhibitory control, but it is still unclear which cognitive processes are used for successful performance of the task. Previous results have provided evidence for the involvement of several processes, including working memory (WM), inhibition and attention. Thus, the aim of this study was to explore, using a range of neuropsychological tests, which cognitive factors predict individual differences in AS performance. To do so, 143 healthy participants underwent a battery including tests measuring inhibition, working memory, cognitive flexibility, sustained attention, IQ and fluency. Hierarchical stepwise regression analyses were conducted to assess the association with AS performance. Performance on the Trail-Making-Test, version B (TMT-B), a test measuring flexibility, divided attention and WM, was found to significantly predict AS latency. Rapid Visual Information Processing (RVIP), used to assess sustained attention and WM, significantly predicted AS error rate. Other cognitive measures, however, did not significantly predict AS performance. Bayesian Model Averaging supported these conclusions and showed that non-significant predictors are unlikely to be associated with AS outcomes. Several explanations are provided for the associations of TMT-B and RVIP with AS performance; as the tests measure a range of different cognitive processes, interpretation of these results remains less clear. For a better understanding of the cognitive mechanisms underlying AS performance, future research should make use of a wider range of attention and WM tests.

The impact of cognitive load on processing efficiency and performance effectiveness in anxiety: evidence from event-related potentials and pupillary responses.

Anxiety has been associated with poor attentional control, as reflected in lowered performance on experimental measures of executive attention and inhibitory control. Recent conceptualisations of anxiety propose that individuals who report elevated anxiety symptoms worry about performance and will exert greater cognitive effort to complete tasks well, particularly when cognitive demands are high. Across two experiments, we examined the effect of anxiety on task performance and across two load conditions using (1) measures of inhibitory control (behavioural reaction times and eye-movement responses) and (2) task effort with pupillary and electrocortical markers of effort (CNV) and inhibitory control (N2). Experiment 1 used an oculomotor-delayed-response task that manipulated load by increasing delay duration to create a high load, relative to a low load, condition. Experiment 2 used a Go/No-Go task and load was manipulated by decreasing the No-Go probabilities (i.e., 20% No-Go in the high load condition and 50% No-Go in the low load condition). Experiment 1 showed individuals with high (vs. low) anxiety made more antisaccade errors across load conditions, and made more effort during the high load condition, as evidenced by greater frontal CNV and increased pupillary responses. In Experiment 2, individuals with high anxiety showed increased effort (irrespective of cognitive load), as characterised by larger pupillary responses. In addition, N2 amplitudes were sensitive to load only in individuals with low anxiety. Evidence of reduced performance effectiveness and efficiency across electrophysiological, pupillary, and oculomotor systems in anxiety provides some support for neurocognitive models of frontocortical attentional dysfunction in anxiety.

VERBAL FLUENCY AND ITS ASSOCIATION WITH INHIBITORY CONTROL IN CHILDREN GRADES 1-3

Verbal fluency (VF) is a good indicator of a child’s academic prowess and later academic success. The goal of the present study was to examine the association between VF and inhibitory control. An additional goal was to examine the developmental trajectories of VF in relation to the grade and gender of the children. The sample for this study consisted of 210 children attending grades 1 to 3. Children’s performance was measured on two VF tasks: semantic fluency and phonological fluency. As a measure of inhibitory control we used a number of commission errors committed on the Multiple Choice Reaction Test. The results of this study indicate the lack of association between VF and inhibitory control. Children improved significantly in VF from grade 1 to grade 3. In relation to gender, girls outperformed boys on the test of phonological fluency but not on the test of semantic fluency. Given the importance of VF, these skills need to be tackled during the elementary school period and even earlier in preschool.

Deficits in Inhibitory Control May Place Service Members at Risk for Posttraumatic Stress Disorder and Negative Parenting Behavior Following Deployment-Related Trauma.

This study examined the mediating role of posttraumatic stress disorder (PTSD) symptoms in the association between deployment-related trauma exposure and parenting behaviors in reserve-component military service members and whether this association was contingent upon parent inhibitory control (IC). Participants were 181 postdeployed fathers and their children. Fathers completed a neurospychological test of IC and self-report measures of trauma exposure and PTSD symptoms. Measures of parenting behaviors (positive engagement and reactivity coercion) were obtained from direct observation of father-child interaction. Results demonstrated that (a) fathers' PTSD symptoms indirectly mediated the effect of trauma exposure on both measures of parenting (i.e., negative indirect effect for positive engagement, point estimate = -.0045, 95% CI [-.0107, -.0003], and positive indirect effect for reactivity coercion, point estimate = .0061, 95% CI [.0007, .0146]); (b) fathers' IC skills moderated the association between trauma exposure and PTSD, β = .14, p = .043, such that the association was positive and significant for fathers with high and medium IC but nonsignificant for fathers with low IC; and (c) the indirect effect of trauma exposure on both parenting measures through PTSD was dependent upon IC, point estimate = .0341, 95% CI [.0005, .0687]. These findings indicate that fathers with low IC skills tended to have higher rates of PTSD symptoms and related negative parenting behaviors, even for individuals with relatively low degrees of deployment-related trauma exposure. Results highlight the importance of IC as a potential moderating factor in the association between trauma exposure, PTSD, and parenting.

Event-related potential correlates of recognition memory in asymptomatic individuals with CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common form of hereditary stroke disorder and is caused by mutations of the NOTCH3 gene. Cognitive decline in CADASIL is characterized by early impairments of attention, memory, and executive functions. Studying asymptomatic individuals with CADASIL offers a unique genetic model to understand preclinical vascular cognitive impairment and dementia. This study aimed at examine whether early preclinical physiological changes could be observed in asymptomatic individuals with CADASIL, who will go on to develop vascular cognitive impairment and dementia later in life. Twenty-nine individuals (mean age: 54.1 years old) were included in the study; five CADASIL NOTCH3 mutation carriers and twenty-five age-matched non-carriers. Participants underwent a comprehensive clinical evaluation and neuropsychological testing. Event-related potentials (ERPs) were recorded during a picture recognition memory task. Analyses focused on the early frontal effect and parietal effect ERP components associated with familiarity and recollection memory. There were no differences between groups in behavioral performance during recognition memory discrimination or cognitive performance. Compared to non-carriers, CADASIL carriers had decreased amplitudes in both ERP components for hits and correct rejections. Among mutation carriers, lower amplitude at 500–600 ms in the left parietal region of interest for correct rejections was correlated with worse performance on measures of semantic fluency and inhibitory control. We conclude that cognitively unimpaired CADASIL carriers showed abnormalities in the neural correlates of recognition memory, years before clinical onset. Early disruptions of fronto-subcortical networks may explain preclinical changes in brain function during recognition memory. This work also demonstrates the potential usefulness of ERP brain correlates as preclinical markers of vascular dementia.

A multimethod study of inhibitory control and behavioural problems in preschoolers

AbstractLow levels of inhibitory control (IC) are associated with multiple cognitive and socio‐emotional difficulties including externalizing behavioural problems and attention deficit hyperactivity disorder (ADHD). However, conclusions depend somewhat on the method of IC assessment. This investigation examined associations between child IC and behavioural problems and maternal depression and anxiety employing a family study design. Child IC was assessed using a parent rating scale, three independent observer ratings, two laboratory‐based temperament episodes, and an executive functioning task. Correlational results showed that parent‐rated IC was associated with all behavioural problems' scales, whereas observed IC was specifically associated with ADHD, aggressive, attention, and externalizing behavioural problems. Structural equation modelling analyses including child age and gender indicated that all IC variables significantly predicted externalizing and ADHD behavioural problems. The model accounted for overlapping variance across parent‐rated IC, child behavioural problems, and maternal mental health symptoms and showed that observed IC predicted externalizing and ADHD behavioural problems over and above these parent–rater effects. Results also showed that maternal depression and anxiety symptoms significantly predicted these behavioural problems even after controlling for the parent‐rater effects. These findings indicate that assessment methods are an important consideration when interpreting the results of early IC investigations.Highlights Do different measures of inhibitory control (IC) predict behaviour problems during preschool? SEM analyses indicated that observed IC predicted externalizing and ADHD behaviour problems over and above parent‐rater effects. Observations of IC show more specificity to externalizing and ADHD problems and are not susceptible to parent‐rater effects.

Dogs and wolves do not differ in their inhibitory control abilities in a non-social test battery

Being able to inhibit certain behaviours is of clear advantage in various situations. In particular, it has been suggested that inhibitory control plays a role in problem-solving and cooperation. Interspecific differences in the capacity for inhibitory control have been attributed to social and ecological factors, while one additional factor, namely domestication, has received only little attention so far. Dogs are an interesting species to test the effects of socio-ecological factors and also the influence of domestication on inhibitory control abilities. While dogs might have been selected for enhanced inhibition skills during domestication, the predictions derived from their socio-ecological background are reversed. Wolves are cooperative hunters and breeders, while dogs predominately scavenge and raise their young alone, accordingly, it would be predicted that dogs show impaired inhibitory control abilities since they no longer rely on these coordinated actions. To test these hypotheses, we assessed inhibitory control abilities in dogs and wolves raised and kept under similar conditions. Moreover, considering the problem of context-specificity in inhibitory control measures, we employed a multiple-test-approach. In line with previous studies, we found that the single inhibition tests did not correlate with each other. Using an exploratory approach, we found three components that explained the variation of behaviours across tests: motivation, flexibility, and perseveration. Interestingly, these inhibition components did not differ between dogs and wolves, which contradicts the predictions based on their socio-ecological backgrounds but also suggests that at least in tasks with minimal human influence, domestication did not affect dogs’ inhibitory control abilities, thus raising questions in regard to the selection processes that might have affected inhibitory control abilities during the course of domestication.

Developmental differentiation of executive functions on the NIH Toolbox Cognition Battery.

The NIH Toolbox Cognition Battery (NTCB) is a brief computerized method for evaluating neuropsychological functions in children, adolescents, and adults. We examined how performance on the 2 executive function measures of cognitive flexibility and inhibitory control was related to performance on the other NTCB measures across development. Participants were 1,020 typically developing individuals between the ages of 3 and 21 from the Pediatric Imaging, Neurocognition, and Genetics Study who were divided into 5 age groups (3-6, 7-9, 10-13, 14-17, and 18-21). Scores were adjusted for sex, level of parental education, and family income. Although the correlations between the 2 executive function measures were moderate and consistent across age groups, their correlations with the other 5 cognitive measures were highest in the youngest age group and decreased across the older age groups. Exploratory factor analysis revealed that all NTCB measures loaded onto a single factor for the 3- to 6-year-olds. Across the older age groups, the executive function and processing speed measures loaded onto one factor, and the vocabulary knowledge, oral reading, and working memory measures loaded onto a second factor. These results indicate that younger children's performance on the NTCB is more intercorrelated and less differentiated, while performance on the NTCB executive function measures becomes more differentiated from performance on the other measures with development. These results support the hypothesis that executive functions become increasingly differentiated from other cognitive functions with development as the functional specialization of neural systems progresses throughout childhood and young adulthood. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Factors affecting the measure of inhibitory control in a fish (Poecilia reticulata)

Inhibitory control allows an individual to block automatic responses as well as to control behaviour and attention. There is growing evidence that many species possess this ability, although the difference in performance among species is great. Inhibitory control has been frequently measured using the detour task: a desired reward is placed behind a transparent barrier, and the animal has to inhibit the tendency to directly move toward the goal, instead making a detour around the barrier. Mammals’ and birds’ inhibitory performance varies according to several factors, such as the distance from the reward and its value, and in dogs, the breed also affects it. We investigated whether these factors affected performance in a fish, the guppy (Poecilia reticulata), by using the detour task, with reaching a social group as goal. We found that guppies were more proficient in making a detour around the barrier when the goal was far, but the value of the reward (i.e., the size of the social group) had no effect. We also found a clear effect of strain, with the guppies that descended from a wild population performing better than the domesticated guppies. Our study revealed that some of the factors affecting inhibitory control in warm-blooded vertebrates also modulate the performance of fish. These factors should be taken into account when comparing this function across species.

Cross-magnitude interactions across development: Longitudinal evidence for a general magnitude system.

There is general agreement that humans represent numerical, spatial, and temporal magnitudes from early in development. However, there is disagreement about whether different magnitudes converge within a general magnitude system and whether this system supports behavioral demonstrations of cross-magnitude interactions at different developmental time points. Using a longitudinal design, we found a relation between children's cross-magnitude interactions assessed at two developmental time points with different behavioral measures. More specifically, stronger cross-magnitude interactions in infancy (M = 9.3 months) predicted a stronger cross-magnitude congruity effect at preschool age (M = 44.2 months), even when controlling for performance on measures of inhibitory control, analogical reasoning, and verbal competence at preschool age. The results suggest a common mechanism for cross-magnitude interactions at different points in development as well as stability of the underlying individual differences. We argue that this mechanism reflects a nonverbal general magnitude system that is operational early in life and that displays continuity from infancy to preschool age.

A study of the developing relations between self-regulation and mathematical knowledge in the context of an early math intervention

Many children from low-income families who have received a generally effective pre-k math intervention nevertheless enter kindergarten behind their middle-income peers in math readiness. To better understand why, research has recently begun to examine the role of self-regulation in children’s early mathematical learning and development. The present study examined (1) the directionality of relations between mathematical knowledge and self-regulation skills, specifically inhibitory control and persistence, within the context of a two-year preschool math intervention; (2) whether participation in a math intervention had a direct impact on either inhibitory control or persistence; and (3) whether self-regulation moderates the impact of math interventions on children’s math outcomes. Participants were 526 low-income preschoolers who were participating in an efficacy study of two early math interventions. Children were assessed on early math and self-regulation skills three times over two years of preschool. Results indicated a bidirectional relation between children’s measures of delay inhibitory control and mathematical knowledge, and children’s mathematical knowledge predicted conflict inhibitory control and persistence. Participation in a math intervention had a direct impact on persistence, but self-regulation skills did not moderate the impacts of participation on either math intervention. Thus, a complex set of relations exists between self-regulation and mathematical knowledge in early childhood. This suggests that the effectiveness of early math interventions might be enhanced by concomitant interventions that target self-regulation.

The effect of beliefs about alcohol's acute effects on alcohol priming and alcohol-induced impairments of inhibitory control.

Acute alcohol administration can lead to a loss of control over drinking. Several models argue that this ‘alcohol priming effect’ is mediated by the effect of alcohol on inhibitory control. Alternatively, beliefs about how alcohol affects behavioural regulation may also underlie alcohol priming and alcohol-induced inhibitory impairments. Here two studies examine the extent to which the alcohol priming effect and inhibitory impairments are moderated by beliefs regarding the effects of alcohol on the ability to control behaviour. In study 1, following a priming drink (placebo or .5g/kg of alcohol), participants were provided with bogus feedback regarding their performance on a measure of inhibitory control (stop-signal task; SST) suggesting that they had high or average self-control. However, the bogus feedback manipulation was not successful. In study 2, before a SST, participants were exposed to a neutral or experimental message suggesting acute doses of alcohol reduce the urge to drink and consumed a priming drink and this manipulation was successful. In both studies craving was assessed throughout and a bogus taste test which measured ad libitum drinking was completed. Results suggest no effect of beliefs on craving or ad lib consumption within either study. However, within study 2, participants exposed to the experimental message displayed evidence of alcohol-induced impairments of inhibitory control, while those exposed to the neutral message did not. These findings do not suggest beliefs about the effects of alcohol moderate the alcohol priming effect but do suggest beliefs may, in part, underlie the effect of alcohol on inhibitory control.

Intra-individual variation in performance on novel variants of similar tasks influences single factor explanations of general cognitive processes.

Intra-individual variation in performance within and across cognitive domains may confound interpretations of both domain-general and domain-specific abilities. Such variation is rarely considered in animal test batteries. We investigate individual consistency in performance by presenting pheasant chicks (n = 31), raised under standardized conditions, with nine different cognitive tasks. Among these tasks were two replicated novel variants of colour learning and colour reversal problems, tests of positional learning and memory, as well as two different tasks that captured multiple putative measures of inhibitory control and motor-related performance. These task variants were also used to compare subjects' performance on alternative test batteries comprised of different task combinations. Subjects’ performance improved with experience, yet we found relatively little consistency in their performance, both within similar tasks using different paradigms and across different tasks. Parallel analysis revealed non-significant factors when all nine tasks were included in a principal axis factor analysis. However, when different combinations of six of the nine tasks were included in principal axis factoring, 14 of 84 combinations revealed significant main factors, explaining between 28 and 35% of the variance in task performance. While comparable findings have been suggested to reflect domain-general intelligence in other species, we found no evidence to suggest that a single factor encompassed a diverse range of cognitive abilities in pheasants. Instead, we reveal how single factor explanations of cognitive processes can be influenced by test battery composition and intra-individual variation in performance across tasks. Our findings highlight the importance of conducting multiple tests within specific domains to ensure robust cognitive measures are obtained.

Developmental trajectories of executive functions in young males with fragile X syndrome

BackgroundExecutive functions (EF) have been identified as impaired in FXS, but few studies have examined their developmental trajectories. AimsThe primary aim of this longitudinal study was to examine the development of EF in young males with FXS compared to Mental Age (MA)-matched controls. Methods and ProceduresThe sample comprised 56 boys with FXS (ages 7–13 years), and 48 MA-matched typical boys (ages 4–8 years). EF tasks included measures of inhibitory control, working memory, cognitive flexibility/set-shifting, problem solving/planning, and processing speed. Tasks were administered at three time points over five-years. Outcomes and ResultsThe MA-Matched Typical boys significantly outperformed the FXS boys on all EF tasks, with the FXS Group showing a pattern of slow, but positive growth on most EF tasks. For working memory tasks, significant interactions were noted between MA and autism symptom severity, and MA and medication status. The probability of task completion increased with higher MA. Conclusions and ImplicationsThese findings contribute to our understanding of the development of EF in this population. They also lay the foundation for use of EF tasks in treatment efforts, particularly with respect to documenting improvements and practice effects, and in understanding associations with targeted developmental outcomes.

Exploring N-Back Cognitive Training for Children With ADHD

Objective: The efficacy of n-back training for children with attention deficit hyperactivity disorder (ADHD) was tested in a randomized controlled trial. Method: 41 children aged 7 to 14 years with ADHD were trained on an n-back task, and their performance was compared with that of an active control group (n = 39) who were trained on a general knowledge and vocabulary task. Results: The experimental group demonstrated transfer of training to a nontrained n-back task as well as to a measure of inhibitory control. These effects were correlated with the magnitude of training gains. Conclusion: Our results suggest that n-back training may be useful in addressing some of the cognitive and behavioral issues associated with ADHD.

Individual differences in decisiveness: ERP correlates of response inhibition and error monitoring.

The aim of the current study was to examine whether and how self-reported decisiveness is associated with response inhibition and performance monitoring. We hypothesized that these two cognitive control mechanisms, both of which are often associated with decision making, would differ in individuals varying in decisiveness. We focused on ERP correlates and behavioral measures of inhibition and error processing in the stop-signal task. We expected a negative relationship between decisiveness and behavioral measures of inhibitory control. We also hypothesized that stop-signal-locked N1 and P3 components and response-locked error-related negativity (ERN) would be less pronounced when participants self-reported higher levels of decisiveness. Correlation analysis identified an association between high decisiveness, long stop-signal reaction time, and low inhibition rate. Analysis with mixed-effects linear models revealed that stop signals evoked less pronounced N1 and P3 in individuals scoring higher on decisiveness in both successfully and unsuccessfully inhibited trials. Additionally, high decisiveness was linked to reduced error monitoring, as indicated by decreased ERNs. Importantly, we also found positive association between P3 onset latency and decisiveness, suggesting that individuals scoring higher on this measure have relatively less ability to rapidly engage the stopping process. Thus, our findings primarily indicate that decisiveness is negatively associated with the efficiency of both response inhibition and error monitoring. They also suggest that highly decisive people may share some characteristics of diminished cognitive control with impulsive individuals.

A New Brief Measure of Executive Function: Adapting the Head-Toes-Knees-Shoulders Task to Older Adults.

Executive function (EF) abilities are recognized as components of cognition most likely to show age-related declines. Measurement of EF in older adults is often computer-based, takes place in a laboratory setting, and thus lacks ecological validity. We sought to investigate a new way of measuring EF in older adults by adapting a brief, behavioral measure of EF in children, the Head-Toes-Knees-Shoulders task (HTKS). A sample of 150 community-dwelling older adults (Mean age = 68.55, SD = 6.34) completed the HTKS, NIH Toolbox: Cognition Battery (NIHTB-CB) and Positive and Negative Affect Schedule. The HTKS showed adequate internal consistency, α = .84. Significant associations between HTKS variables and measures of attention and inhibitory control were robust to the influences of age, processing speed, and subjective health ratings. HTKS completion time exhibited the strongest associations to NIHTB-CB measures, suggesting that the time it takes older adults to complete the HTKS may be a better measure of EF than the total score. Nonsignificant associations between HTKS variables and positive and negative affect demonstrated discriminant validity. These results provide initial evidence for use of the HTKS as a brief, low-cost, easy to administer measure of EF in older adults. Further research is needed to determine its potential to identify individuals at risk for poor cognitive outcomes. A brief, valid measure may allow for wider screenings aimed at early intervention, when cognitive interventions are most effective.

Cognitive control ability mediates prediction costs in monolinguals and bilinguals

In this study, we examined the role that cognitive control and language regulation ability play in mediating readers’ susceptibility to prediction error costs when reading in the native language (L1) or a second language (L2). Twenty-four English monolinguals (Experiment 1) and 28 Chinese-English bilinguals (Experiment 2) read sentences in English while their EEG was recorded. The sentences varied in the predictability of an upcoming expected word and in whether that prediction was confirmed. Monolinguals showed sensitivity to sentence contexts in which expectations were not met (i.e., when unexpected words were encountered) in the form of a late, frontally-distributed positivity, but for bilinguals this effect was more complex. For both groups, performance on the prediction task was modulated by individual differences on the AX-CPT, a measure of inhibitory control. However, the bilinguals' reading performance in the L2 was affected not only by inhibitory control, but also by their performance on an L1 verbal fluency task that indexed language regulation and production capability, related to their language dominance and immersion context. Bilinguals with better regulation of the L1 generated a larger frontal positivity in response to unexpected words in the L2, an effect that was attenuated by inhibitory control ability. In contrast, bilinguals with lower regulatory ability generated a larger, late negativity, which was also mediated by control. These findings suggest that the ability to regulate the native language when immersed in a second language environment can influence mechanisms underlying the prediction process when reading in the L2. In addition, cognitive control ability, specifically inhibitory control, appears to mediate the difficulty readers incur when predictions are disconfirmed, not only in the native language, but also for proficient bilinguals reading in the L2. We argue that the mechanisms engaged during prediction in the L1 and L2 are fundamentally the same, and that what differs for bilinguals are the additional demands imposed by their language experience and language use.

Proactive behavior, but not inhibitory control, predicts repeated innovation by spotted hyenas tested with a multi-access box.

Innovation is widely linked to cognitive ability, brain size, and adaptation to novel conditions. However, successful innovation appears to be influenced by both cognitive factors, such as inhibitory control, and non-cognitive behavioral traits. We used a multi-access box (MAB) paradigm to measure repeated innovation, the number of unique innovations learned across trials, by 10 captive spotted hyenas (Crocuta crocuta). Spotted hyenas are highly innovative in captivity and also display striking variation in behavioral traits, making them good model organisms for examining the relationship between innovation and other behavioral traits. We measured persistence, motor diversity, motivation, activity, efficiency, inhibitory control, and neophobia demonstrated by hyenas while interacting with the MAB. We also independently assessed inhibitory control with a detour cylinder task. Most hyenas were able to solve the MAB at least once, but only four hyenas satisfied learning criteria for all four possible solutions. Interestingly, neither measure of inhibitory control predicted repeated innovation. Instead, repeated innovation was predicted by a proactive syndrome of behavioral traits that included high persistence, high motor diversity, high activity and low neophobia. Our results suggest that this proactive behavioral syndrome may be more important than inhibitory control for successful innovation with the MAB by members of this species.