Measures Of Awareness Research Articles

Perceived cultural humility in supervision group and trainees' cultural responsiveness self-efficacy.

Trainees often express anxieties when working with clients from different sociocultural backgrounds. Group supervision can provide a space to address such concerns, including managing culturally related countertransference and understanding sociocultural factors in issues faced by clients. This process requires critical consciousness and discussion of trainees' and clients' cultural identities. This study built on research highlighting the positive role of cultural humility in individual supervision and group therapy to examine cultural humility in group supervision and its contribution to trainees' self-efficacy in adapting therapy and managing relationship conflicts with a range of clients (i.e., cultural responsiveness self-efficacy), via sociocultural awareness and minimal cultural concealment about themselves and their clients. Ninety-one master's level counseling trainees in Hong Kong from 18 supervision groups in two training programs completed measures of cultural humility, cultural concealment, sociocultural awareness, and cultural responsiveness self-efficacy. Multilevel modeling indicated that, at the within-trainee level, higher group cultural humility was associated with higher sociocultural awareness and lower cultural concealment about themselves and their clients. Greater sociocultural awareness, but not cultural concealment, was, in turn, linked to higher cultural responsiveness self-efficacy. At the between-trainee level, higher group cultural humility correlated with lower trainee cultural concealment, but not sociocultural awareness, which was associated with cultural responsiveness self-efficacy, although no mediation was observed. This study underscores the value of cultural humility in the context of group supervision. Implications for multicultural group supervision are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Uncovering the intensity of climate risk and opportunity: Awareness and effectiveness

This paper examines the effect of awareness regarding climate change risks and opportunities on the proactive carbon management systems of U.S. S&P 500 companies. We develop our hypotheses based on institutional theory, stakeholder theory, and prospect theory. Our findings indicate a significant positive association between our self-constructed measurement of company risk and opportunity awareness and carbon management practices. We observe that financially constrained firms exhibit a lesser response to both climate change risk and opportunity awareness. Additionally, we note that firms with low profitability are more responsive to climate change risks, whereas we found no evidence linking climate change opportunity awareness to carbon management systems, consistent with prospect theory. Finally, we investigate the impact of carbon management systems on carbon reduction performance to examine the effectiveness of such awareness. In summary, this study provides the first evidence of how awareness of climate risk and opportunity influences corporate carbon management practices in a U.S. setting. Our findings imply that awareness serves as the initial step in prompting positive actions to manage risks and capitalize on opportunities. These results offer novel insights and information relevant to the recent policy initiative aimed at transitioning climate risk disclosure from voluntary to mandatory.

Cardiovascular disease risk factors prediction using deep learning convolutional neural networks

Heart disease remains a leading cause of mortality worldwide, prompting healthcare researchers to leverage analytical tools for comprehensive data analysis. This study focuses on exploring crucial parameters and employing deep learning (DL) techniques to enhance understanding and prediction of cardiovascular disease (CVD) risk factors. Utilizing SPSS and Weka tools, a cross-sectional and correlational design was employed to analyze extensive medical datasets. Binomial regression analysis revealed significant associations between age (𝑝 = 0.004) and body mass index (𝑝 = 0.002) with CVD development, highlighting their importance as risk factors. Leveraging Weka's DL algorithms, a predictive model was constructed to classify CVD causes. Particularly, convolutional neural networks (CNN) showcased remarkable accuracy, reaching 98.64%. The findings underscore the elevated risk of CVD among university students and employees in Saudi Arabia, emphasizing the need for heightened awareness and preventive measures, including dietary improvements and increased physical activity. This study underscores the importance of further research to enhance CVD risk perception among students and individuals in similar settings.

Understanding climate change awareness and adaptation measures in urban settings: A study in Surakarta, Indonesia

Backgorund: The effects of climate change in the atmosphere are starting to manifest, impacting not only the natural world but also human cultures. In Indonesia, these impacts are expected to intensify over the coming decades, with rising temperatures, declining rainfall, and sea-level rise affecting coastal areas. Extreme weather events, such as flooding and droughts, are becoming more common, posing significant challenges to human existence, economic growth, and the natural environment. This research aims to provide a comprehensive understanding of climate change awareness and adaptation measures among adolescents and local people in Surakarta, Indonesia. The study seeks to assess how the local population perceives and responds to climate change, as well as to identify factors that make communities vulnerable to severe weather events. By exploring these factors, the study aims to shed light on the underlying causes of vulnerability and inform the development of effective adaptation and mitigation strategies. Method: The research methodology involves the use of structured questionnaires and surveys to collect data from 100 respondents in Surakarta. Statistical analysis, including regression analysis, is employed to assess the relationship between various demographic factors and climate change awareness. Demographic factors such as age, education level, and income are evaluated to understand their impact on climate change perception and responsiveness. Findings: The findings of the study highlight the importance of enhancing climate change knowledge among adolescents and local residents and underscore the need for targeted adaptation measures to address the unique challenges faced by urban communities in Surakarta. Conclusion: Overall, this study contributes to the broader understanding of climate change adaptation and resilience-building efforts in urban settings and provides valuable insights for policymakers, researchers, and community stakeholders working in the field of climate change mitigation and adaptation. Novelty/Originality of this article: Using a structured survey, this study assessed climate change awareness and adaptation measures among adolescents and residents. The findings highlight the importance of improving knowledge about climate change and developing appropriate adaptation strategies for urban communities.

The Effects of a Morphological Awareness Intervention on Reading and Spelling Ability of Children With Dyslexia

This paper examines the effects of a morphological awareness intervention on the word reading and spelling skills of Grades 4 to 6 children with dyslexia. Sixteen children in eastern Ontario, Canada, received 20 hours of morphologically oriented instruction spread over 6 weeks and eight served as controls, and all received a battery of reading and spelling tests before and after the intervention. Students were taught the nature of morphology and the types of morphemes, how words could be assembled from morphemes or deconstructed into morphemes to make meaning from print and access the correct pronunciation, and how to use morphology in reading and spelling words. Repeated measures analyses of variance and analyses of covariance indicated that the experimental group showed significantly larger gains than the control group on measures of morphological awareness, morphological decoding, morphological analysis, and morphological spelling. There were no significant effects on word reading (fluency and accuracy) or on standardized spelling measures.

Evaluation of Water Quality Indexes and Heavy Metal Pollution Indexes of Different Industrial Effluents and Karnaphuli River Water in Chattogram, Bangladesh

ABSTRACTThe study evaluated the water quality index (WQI) and heavy metal pollution index (HPI) of different industrial effluent and surface water from various sites of the Karnaphuli River, based on the weighted arithmetic index method. The samples were collected from 20 different industries, including textile dyeing, textile washing, oil processing, chemicals, and tannery, and 17 stations of the Karnaphuli River, from the Kalurghat Bridge to the estuary where the river meets with the Bay of Bengal. This study was carried out in the dry season of the 2021–2022 fiscal year. Six physicochemical parameters, namely pH, biochemical oxygen demand, chemical oxygen demand, total dissolved solids, electrical conductivity, and hardness, were taken for the determination of the WQI, and concentration of heavy metals (Pb, Fe, Cd, Cu, Cr, Mn, and Ni) were considered for the calculation of the HPI. Both indexes were calculated against the Bangladesh Standard (denoted by subscript a) and WHO standards (denoted by subscript b). The water quality indexes WQIa and WQIb for industrial effluent ranged from 11.66 to 176.77 and 44.45 to 9703.99, respectively. Samples namely TD‐5, TD‐7, TD‐8, TD‐9, TD‐10, OS‐1, and C‐1 showed excessively high WQI value. On the other hand, the HPIa and HPIb of industrial effluent varied from 43.6 to 167,785.3 and 0.34 to 18,412.3, respectively. Furthermore, oil processing and chemical effluents showed noticeably higher HPI values than other industrial samples. Both WQI and HPI values indicated a serious pollution load in most experimental samples. No river water sample showed a WQI value below 100, denoting it was unfit for consumption. The water quality indexes WQIa and WQIb for river water samples ranged from 1275.40 to 29,405.77 and 131.20 to 5860.99, respectively. According to the Bangladesh Standard, the river water samples were moderately to highly polluted by metal. The highest HPI value for the river water sample was 7965, denoting extreme metal pollution. The investigation revealed that most industrial effluents and Karnaphuli River water samples contained significant pollution load. Therefore, effective measures must be adopted immediately for future sustainability to cope with this contamination. The results emphasize the immediate requirement for strict regulations and advanced water treatment technologies to reduce contamination risks in the Karnaphuli River. Prompt action by authorities is essential to safeguard the river, prevent ongoing ecological damage, and address metal accumulation in fish affecting the food chain. Public awareness and legislative measures are vital for ecosystem preservation.

Pathogenic Leptospira interrogans in Jos North Abattoir, Nigeria: Occurrence, serology, and molecular characterization

Leptospirosis, a neglected zoonotic disease, adversely affects animal, human health, and socioeconomic conditions, particularly in developing countries like Nigeria. This study aimed to determine the occurrence and molecular identification of pathogenic Leptospira spp. among abattoir workers, cattle, and rats in Jos North, Plateau State, Nigeria. Using a cross-sectional study design, a total of 394 samples were collected, including 149 urine samples from abattoir workers, 125 urine samples from cattle bladders, and 120 bladders from trapped rats. Samples were processed and cultured in Ellinghausen McCullough Johnson Harrison (EMJH) medium and examined under a darkfield microscope. Positive cultures were confirmed using the Microscopic Agglutination Test (MAT) and nested Polymerase Chain Reaction (N-PCR) targeted the 16 S rDNA gene. Results revealed a prevalence of 33.76 % for Leptospira spp. across all samples, with the highest occurrence in abattoir workers (13.96 %), followed by rats (13.45 %), and cattle (6.35 %). The MAT showed L. interrogans serovar Hardjo str. Hardjoprajitno as the most prevalent serotype (41.61 %), followed by L. interrogans serovar Icterohaemorrhagiae str. RGA (34.31 %). N-PCR confirmed the presence of pathogenic Leptospira spp., showing bands of 1200 bp. Phylogenetic analysis of the 16 S rDNA gene sequences revealed close similarities to known pathogenic Leptospira strains from Brazil and the USA. The study underscores the significant public health risk posed by leptospirosis in Jos North and highlights the need for improved diagnostic capabilities, increased awareness, and effective control measures to mitigate the disease burden. Enhanced surveillance and preventive strategies are crucial to protect both animal and human health in the region.

Academic Students' Awareness, Attitudes, and Preventative Measures Regarding COVID-19 in Riyadh, Saudi Arabia

Background: Coronavirus is exceedingly contagious, and an effective treatment has yet to be identified. However, its transmission can be halted or slowed by employing preventative measures and remaining informed about the disease and its mode of transmission. Objectives: This study investigates the knowledge, attitudes, and behaviors of Riyadh schoolchildren regarding COVID-19. Method: From April to June of 2022, this cross-sectional research involved students between the ages of 12 and 18 from various schools in Riyadh. The information was gathered via an internet-based survey employing a pre-validated Arabic survey questionnaire. Results: A significant majority of 253 students (91.3%) exhibited a profound comprehension of the transmission of COVID-19. In addition, headache 87.7%, loss of taste and smell 92.5%, and fever 94.5% were the most frequently reported symptoms by students. The high knowledge score was predicted by secondary school students versus intermediate school students (OR=0.243, 95%CI: (0.072-0.819), p<0.05) and elder versus younger students (OR=0.306, 95%CI: (0.092-1.024), p<0.05). A majority of students (69.2%) express support for notifying health authorities of any symptoms they experience, while 71.9% consent to isolation should they come into contact with an infected individual. Preventive measures were practiced with greater zeal by female students compared to male students (P-value <0.0001). Information was obtained primarily through social media. Conclusion: The majority of respondents were informed, held logical views, and took preventative measures against COVID-19. The fact that respondents became aware of COVID-19 through social media demonstrates the positive impact it has had on public health consciousness. Our research may not reflect the knowledge, attitudes, and preventative behaviors of Riyadh pupils regarding COVID-19. It furnishes vital data to aid health organizations in the development and execution of preventive initiatives.

Perceptions of prostate cancer patients undergoing definitive radiotherapy on the impact of prostate cancer and radiation therapy on male sexuality.

Male sexual function is an important aspect of the life of prostate cancer patients and plays a significant role in the long-term quality of life of prostate cancer survivors. However, there is a paucity of published literature on the perceived impact of prostate cancer and its treatment on the sexual function of patients in Ghana and West Africa in general. The purpose of this study was to explore the perceptions of prostate cancer patients on the effects of the disease and radiation therapy on male sexual function. The study also examined the changes in sexuality experienced by men with prostate cancer. This research was a descriptive longitudinal study conducted at the third largest hospital in Africa. The study included Ghanaian prostate cancer patients of all ages who were treated with definitive radiotherapy at the study site between October 2021 and May 2022. Quantitative data were collected and analysed using the Statistical Package for Social Sciences version 26.0 and Microsoft Excel 2019. Descriptive statistics were used to determine frequencies and percentages of the demographic characteristics. The mean age of the participants was 65.7 years (SD 6.7) ranging from 50 to 81 years. Patients had different ideas about the potential adverse effects of prostate cancer (86%) and radiotherapy (70%) on male sexual function. A decrease in sexual desire (54%) was the commonest perceived effect of prostate cancer on male sexual function followed by premature ejaculation (49%) and a decrease in sexual activity (48%). On the other hand, erectile dysfunction (49%) was the commonest perceived effect of radiotherapy for prostate cancer on male sexual function followed by a decrease in sexual desire (38%) and premature ejaculation (37%). Health professionals were the major source of information regarding the perceptions of the patients on the effects of both prostate cancer (46%) and radiation therapy (43%) on male sexual function. There should be enhancement of awareness measures to educate Ghanaian cancer patients on the side effects and implications of treatment on their sexuality. Comprehensive sexual health assessment should be incorporated in the routine care of patients with cancers that have the potential to impact the sexual function of patients.

EMOTONGUE, a smartphone application designed to promote awareness and consequent emotional self-regulation measure emotions in natural contexts

EMOTONGUE is an Android application designed to help people become more aware of their own emotions, facilitating emotional self-regulation processes in their daily lives. The app was evaluated in a study with 16 participants. They used the app five times a day for two weeks. The aim was to improve emotional management, emotional granularity and perception of emotional intensity. A mixed methods design was used, combining qualitative and quantitative approaches. Results indicated progressive improvements in self-awareness and emotional management, as well as in emotional granularity, by achieving app-based labelling of emotions in a more specific way. Differences in emotional expression were observed between native and second languages, as well as in the frequency of use of emotions related to arousal and/or pleasure due to cultural and/or gender nuances. Although the results suggest the efficacy of the app, a larger sample size is required to confirm them. This study highlights the importance of accessible tools in psychology and education to benefit more people.

Prenatal Mindfulness Training and Interoceptive Awareness in Pregnant People at Risk for Hypertensive Disorders.

Aim: In this secondary analysis of a pilot randomized controlled trial (RCT), we sought to examine whether mindfulness training (MT) is associated with change in interoceptive awareness in pregnant people at risk for hypertension using quantitative and qualitative methods. Interoceptive awareness is the perception, regulation, and integration of bodily sensations. Interoceptive awareness increases following MT and has been proposed as a psychosomatic process underlying hypertension outside of pregnancy. Methods: Twenty-nine participants (mean age 32 ± 4 years; 67% White) with a history of hypertensive disorders of pregnancy (HDP) were enrolled at 16 weeks' gestation (SD = 3) for a RCT assessing the feasibility and acceptability of an 8-week phone-delivered MT intervention. Fifteen participants were randomized to MT, whereas 14 were randomized to usual prenatal care. Before and after the intervention, all participants completed the Multidimensional Assessment of Interoceptive Awareness (MAIA) measure and participated an individual interview, which queried for mind-body changes noticed across the study period. Results: Adjusting for baseline interoceptive awareness and gestational age, participants randomized to MT reported less worry about physical sensations on the MAIA after the intervention compared to those randomized to usual care. Qualitative data corroborated these results; MT participants described improved awareness of body and breath sensations, ability to notice blood pressure changes, non-judgmental observation of thoughts, and improved responses to interpersonal challenges. Conclusions: MT may improve the ability to notice body sensations that arise in pregnancy in a way that promotes healthy responding rather than worry. Results provide support for interoceptive awareness as a potential mechanism through which mindfulness may modulate blood pressure and potentially reduce the prevalence of HDP. Clinical Trial Registration: ClinicalTrials.gov (NCT03679117).

Awareness of cancer and its associated factors for parents of adolescents and young adults: A cross-sectional study.

Cancer is a common health problem worldwide. Early cancer education for adolescents and young adults (AYAs) is important for the prevention or early detection of cancer. In this questionnaire-based cross-sectional study, we examined the cancer awareness among parents of AYAs. Japanese adults with junior or senior high school children were included in this study. The cancer awareness measure (CAM) was used to assess cancer awareness, and the survey was conducted in December 2021. Warning signs, barriers to seeking help, and risk factors were surveyed using an online anonymous questionnaire. In addition, personal information, the presence of other cancer survivors, attendance at cancer seminars, conversations with children about cancer, interest in cancer education for children, and previous cancer screening were surveyed. A t-test or Spearman correlation coefficient was used to compare the total CAM scores for the individual factors. The relationship between cancer-screening behavior and individual factors was analyzed using the χ2 test. In addition, multiple regression analysis or logistic regression analysis was used to identify the factors influencing cancer awareness or cancer-screening behavior. Responses were obtained from the 612 participants. The mean CAM score was 3.7 for cancer warning signs, 4.3 for barriers to seeking help, and 6.5 for risk factors. Cancer warning signs were associated with gender and the presence of a spouse, family member, or friend who had experienced cancer. Barriers to seeking help were associated with age, gender, and education, while risk factors were associated with gender, education, and conversations about cancer with children. Moreover, these scores were associated with each cancer screening behavior. Cancer awareness among Japanese adults with AYAs was influenced by gender, academic background, occupation, the presence of cancer survivors around them, and whether they had conversations about cancer with their children, as well as their cancer screening behavior.

P-697 The effect of smoking and vaping on hormonal ovarian reserve markers in women of reproductive age in the United Kingdom

Abstract Study question What impact do smoking and vaping have on ovarian reserve markers Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH)? Summary answer Smoking and vaping negatively affect AMH and FSH levels in women, with significant age-related differences in ovarian reserve markers observed. What is known already Previous studies have established a link between smoking and accelerated ovarian follicular depletion, evidenced by lower serum AMH levels and reduced antral follicle count (AFC). Smoking is known to increase FSH levels indirectly by affecting pituitary function. However, the impact of vaping, a growing trend especially among younger individuals, on ovarian reserve markers like AMH and FSH remains under-researched and requires comprehensive investigation to understand its full implications on reproductive health. Study design, size, duration This cross-sectional study analysed medical history and serum AMH and FSH concentrations from capillary blood samples of 8,340 women aged 21-45. Participants were stratified by 5-year age intervals and excluded if they had reproductive health conditions or used hormonal contraception. Samples were analysed from individuals using an at-home hormone testing service, with statistical analysis including unpaired t-tests and Cohen’s d for effect size, focusing on smokers/vapers versus non-smokers/non-vapers. Participants/materials, setting, methods The study included UK women aged 21-45 providing capillary blood samples for serum AMH and FSH measurement using an at-home testing service. Exclusions applied to those with reproductive conditions or on hormonal contraception. Smoking and vaping status were self-reported through an online health assessment. AMH and FSH concentration differences were analysed via unpaired t-test; a p-value of < 0.05 was considered statistically significant and mean values±SD were reported. Main results and the role of chance Among 8,340 participants, 312 smoked and 653 vaped. Lower serum AMH values were observed in smokers and vapers in all age groups, with significant differences at ages 31-35 for smokers (20.73±16.23 vs 25.37±19.80 pmol/L in smokers and non-smokers respectively; p = 0.003) and 36-40 for vapers (13.65±13.34 vs 16.88±14.32 pmol/L in vapers and non-vapers respectively; p = 0.01). No significant differences in serum FSH concentration were found among vapers, however, FSH levels were higher in smokers across all ages. This was significant in individuals aged 21-25 (8.01±2.52 vs 6.87±3.33 IU/L in smokers and non-smokers respectively; p = 0.02) and 31-35 (8.33±3.31 vs 7.70±3.51 IU/L smokers and in non-smokers respectively; p = 0.04). These results suggest a detrimental effect of smoking and vaping on ovarian reserve markers, with statistical significance indicating the role of chance is minimal in the observed differences. Limitations, reasons for caution Self-reported smoking/vaping status may introduce bias. The study does not report the duration or frequency of participants’ smoking and vaping habits. The study’s cross-sectional design limits causality inference, however it provides a valuable insight for future longitudinal research to explore these relationships over time and explore underlying mechanisms. Wider implications of the findings These findings highlight the potential risks of smoking and vaping on women’s reproductive health, emphasising the need for awareness and preventive measures, especially among younger populations and the increased use of vaping. Trial registration number not applicable

A reduction in self-reported confidence accompanies the recall of memories distorted by prototypes

When we recall a past event, we reconstruct the event based on a combination of episodic details and semantic knowledge (e.g., prototypes). Though prototypes can impair the veracity of recall, it remains unclear whether we are metacognitively aware of the distortions they introduce. To address this, we conducted six experiments in which participants learned object-colour/object-location pairs and subsequently recalled the colour/location when cued with the object. Leveraging unsupervised machine learning algorithms, we extracted participant-specific prototypes and embedded responses in two-dimensional space to quantify prototype-based distortions in individual memory traces. Our findings reveal robust and conceptually replicable evidence to suggest that prototype-based distortion is accompanied by a reduction in self-reported confidence - an implicit measure of metacognitive awareness. Critically, we find evidence to suggest that it is prototype-based distortion of a memory trace that undermines confidence, rather than a lack of confidence biasing reconstruction towards the use of prototypes. Collectively, these findings suggest that we possess metacognitive awareness of distortions embedded in our memories.

Venous thromboembolism during three muslim pilgrimage seasons

Background Acute pulmonary embolism (PE) is a potentially fatal condition for which prompt recognition, risk assessment and appropriate treatment must be implemented to reduce mortality and morbidity. This study was planned to analyze all cases of venous thromboembolism (VTE) admitted to the tertiary care hospital during three successive Muslim hajj seasons. Methods A prospective observational study that included 135 patients of which 65 patients were with deep vein thrombosis (DVT group), 50 patients were with pulmonary embolism (PE group) and 20 patients were with concomitant DVT and PE (DVT/PE group). All patients were subjected to full history taking, clinical examination, laboratory, and radiological studies. Results The presentation with hemodynamic compromise and the percentage of mortality were more in patients with DVT/ PE compared to patients with PE alone. The patients in the DVT group had the highest D-dimer and triglyceride levels. The patients in the PE group had the most severe tachypnea and the highest values of cardiac biomarkers and aminotransferases. The patients in the DVT/PE group had the most rapid average pulse, the lowest average blood pressure, and the lowest oxygen saturation. Conclusions The presentations with DVT or DVT/PE were more in females and presentation with PE without DVT was more in males. Hajjis with VTE presented with less frequent symptoms, more overt clinical signs, more hemodynamic compromise and overall mortality compared to other studies. The study information may encourage the designated health authorities to raise awareness and implement VTE preventive measures during pilgrimage season.

Increasing Public Knowledge About Hypertension as an Effort to Prevent Hypertension Complications (Stroke)

Hypertension is a health disorder that causes an increase in blood pressure. Hypertension can cause serious complications in the form of stroke. These significant complications can be life threatening and even death. Stroke is a global health problem with more than 15 million people annually experiencing this condition worldwide. This study was conducted on 30 individuals who visited the Pagar Jati Community Health Center, using the accidental sampling method, to explore the contribution of community participation in increasing awareness about hypertension and promoting preventive behavior. Through outreach activities and public campaigns, community participation has succeeded in increasing understanding of the importance of regular health check-ups by checking blood pressure and consuming foods with balanced nutrition, including low salt, thereby preventing hypertension. Evaluating the effectiveness of the community service program using a questionnaire showed an increase from 70% at the pretest stage to 93% at the posttest stage. This reflects a significant increase in awareness, knowledge and preventive measures against complications of hypertension, such as stroke, in the community areas served by health community center (Puskesmas) Pagar Jati. Collaboration between health workers, local government, educational institutions and the community is the key to the success of this program. Although challenges remain such as limited access and inequality of information, community service has proven to be an effective tool in strengthening the community response to hypertension and advancing overall community health.

MDMB-4en-PINACA-Related Deaths in Cook County Jail: Awareness and Preventive Measures.

Since January 2023, a series of fatalities has occurred in the Cook County Jail. Upon reviewing surveillance videos, in some cases, the inmates shared paper strips, and it was followed by the onset of labored breathing and loss of consciousness. Scene investigation revealed burnt paper strips near the body in 3 cases. No trauma was observed during autopsy. The expanded toxicology panels did not detect any illegal drugs in the postmortem blood samples. However, additional analysis specifically targeting synthetic cannabinoids revealed the presence of MDMB-4en-PINACA [methyl 3,3-dimethyl-2-{[1-(pent-4-en-1-yl)-1H-indazole-3-carbonyl]amino}butanoate], a synthetic cannabinoid associated with a wide range of adverse effects, including cardiovascular complications such as tachycardia and hypertension, respiratory depression, and acute kidney injury. There is limited research on the lethality of MDMB-4en-PINACA. This case series suggests that even isolated use can potentially lead to death. This study aims to raise public awareness regarding MDMB-4en-PINACA, highlighting its unpredictable effects and potential for severe adverse reactions, and to facilitate the development of effective prevention and harm reduction strategies. Implementing screening methods in correctional facilities is crucial to prevent the circulation of potentially fatal substances.

The Penetration of Environmental Awareness in Organic Chemistry Experiment Teaching

With the continuous development and progress of science and technology and society, the relationship between education and environmental protection is increasingly close, and people's attitude towards pollution is more and more serious, away from the formalism. We have the responsibility and obligation to implement this important measure of environmental awareness in chemistry teaching. Therefore, in this paper, the existing problems and pollution sources of organic chemistry experiments, the necessity and measures to achieve environmental chemistry are described.

BODY AWARENESS, STRESS AND SYMPTOMS IN AUTONOMIC DYSFUNCTION IN PATIENTS WITH CHRONIC PAIN: AN EXPLORATIVE STUDY.

To assess pain outcomes, stress levels and body awareness among patients with chronic pain and explore potential associations between these variables. An explorative study. Patients with chronic pain in primary and specialist care were assessed regarding pain intensity using the Numerical Rating Scale (NRS; 0-10 point scale) and stress levels using the Stress and Crisis Inventory (SCI-93; 0-140). To assess body awareness, multidimensional assessment of interoceptive awareness (MAIA; 0-5), a widely used self-report measure of interoceptive bodily awareness was used. Participants (n = 42) reported an average NRS of 4.4, elevated stress levels and low body awareness. Stress levels were moderately correlated with pain intensity (r = 0.53; p < 0.001; 95% confidence interval [CI] 0.25-0.72) and number of pain sites (r = 0.58; p < 0.001; 95% CI 0.32-0.76). The regression analysis showed that pain outcomes predicted stress level scores and explained almost 50% of variance (R 2 = 0.47, p < 0.001). Moreover, shorter pain duration predicted a higher body awareness (p = 0.04). In patients with chronic pain, high pain intensity and multiple painful sites seem to be associated with impaired stress regulation. The patients had low body awareness, which was negatively influenced by pain duration.

Incidence, healthcare resource utilization and costs of hospitalized patients with tick-borne encephalitis (TBE) in Italy

ObjectiveOur study's objective was to assess the incidence trends and healthcare resource utilization of hospitalizations for Tick-Borne Encephalitis (TBE) and associated costs in Italy in order to improve public awareness and preventive measures. MethodsThis retrospective observational study was based on the Italian Ministry of Health's Hospital Discharge Record (HDR) database. Data were gathered across Italy from 2015 to 2019, selecting hospitalizations with ICD-9 code 063 related to TBE, both in primary and secondary diagnoses. For each year, we collected the following variables: number of hospitalizations, hospitalization rate, mortality rate, mean length of hospital stay, hospital ward, and cost of hospitalization. ResultsThere were a total of 237 hospitalizations from 2015 to 2019; 62 % of those were male. The lowest number of TBE hospitalizations was in 2015 (21 cases, corresponding to 0.35 per million inhabitants), the highest in 2019 (64 cases, 1.04 per million inhabitants). The summer months saw a greater than average number of hospitalizations. For the years analyzed, the cumulative number of cases peaked in June (54 cases), July (46 cases), and August (35 cases). There were only two deaths registered in our study sample. TBE cases were mostly localized in the North-Eastern regions of Italy. TBE incidence during the study period in the most affected areas were: Autonomous Province of Trento, ranging from 11.2 to 42.3 per million inhabitants, Autonomous Province of South Tyrol, from 0 to 21.1 per million inhabitants, and Veneto Region, from 2.6 to 4.5 per million inhabitants. In the study period, the average length of hospital stay was largely stable ranging from 10.6 days to 12.8 days, with related costs ranging from 5,813.7 € to 7,352.5 €. ConclusionsAccording to our data, the majority of TBE hospitalizations occur in North-East Italy with an increasing trend over the analyzed period. Even though Italy has fewer TBE cases than other neighboring European countries, the health and economic impact can be high in the affected areas.