Mean Scores Of Well-being Research Articles

Well-Being and General Anxiety Among University of Michigan Dental Students

BackgroundAnxiety is one of the most prevalent mental health conditions, affecting approximately 1 in 9 people worldwide. More specifically, dental students have been considered vulnerable to anxiety despite the fact that dental students have also reported high levels of well-being. Therefore, we hypothesize that University of Michigan School of Dentistry (UMSOD) dental students pose high levels of well-being but suffer from anxiety. Our objective is to measure anxiety and well-being levels among UMSOD dental students for 2 consecutive academic years.MethodsDental students (N = 609) were surveyed for well-being and general anxiety levels. To assess well-being and anxiety levels we used the World Health Organization–Five Well-Being Index (WHO-5) questionnaire and the General Anxiety Disorder 7-item (GAD-7) scale, respectively. Surveys were sent through Qualtrics. For statistical analysis, chi-square and t test were used at p < 0.05.ResultsThe mean well-being score among dental students was 12.26 (SD = 1.14). In the first survey moment for anxiety, which coincided with the week before the spring break in 2017, approximately 39% of the respondents (n = 255) scored 10 or higher on the GAD-7, which means moderate anxiety. In the second survey moment, the week after the spring break week in 2017, we found a slight but not significant reduction in anxiety levels, with approximately 32% of the responses (n = 109) of the dental students scoring 10 or higher on the GAD-7. Incoming first-year dental students before starting the dental school program presented well-being mean of 18 (SD = 0.60). Only 13% of incoming first-year dental students scored 10 or higher on anxiety before starting the school program. By the fall term, the well-being mean among incoming first-year dental students dropped to 13.29 (SD = 1.32), and 22% of the incoming first-year dental students scored 10 or higher in the GAD-7.ConclusionsUniversity of Michigan School of Dentistry dental students posed poor well-being and moderate anxiety. Incoming first-year dental students posed higher well-being and lower anxiety levels before starting the dental education program. However, as the academic year developed, incoming first-year dental students suffered a decrease in well-being and an increase in anxiety levels. Our study indicates a trend of poor well-being and high anxiety among UMSOD dental students.

An intervention to improve teacher well-being support and training to support students in UK high schools (the WISE study): A cluster randomised controlled trial.

Teachers are at heightened risk of poor mental health and well-being, which is likely to impact on the support they provide to students, and student outcomes. We conducted a cluster randomised controlled trial, to test whether an intervention to improve mental health support and training for high school teachers led to improved mental health and well-being for teachers and students, compared to usual practice. We also conducted a cost evaluation of the intervention. The intervention comprised (i) Mental Health First Aid training for teachers to support students; (ii) a mental health awareness session; and (iii) a confidential staff peer support service. In total 25 mainstream, non-fee-paying secondary schools stratified by geographical area and free school meal entitlement were randomly allocated to intervention (n = 12) or control group (n = 13) after collection of baseline measures. We analysed data using mixed-effects repeated measures models in the intention-to-treat population, adjusted for stratification variables, sex, and years of experience. The primary outcome was teacher well-being (Warwick-Edinburgh Mental Well-being Scale). Secondary outcomes were teacher depression, absence, and presenteeism, and student well-being, mental health difficulties, attendance, and attainment. Follow-up was at months 12 (T1) and 24 (T2). We collected process data to test the logic model underpinning the intervention, to aid interpretation of the findings. A total of 1,722 teachers were included in the primary analysis. Teacher well-being did not differ between groups at T2 (intervention mean well-being score 47.5, control group mean well-being score 48.4, adjusted mean difference -0.90, 95% CI -2.07 to 0.27, p = 0.130). The only effect on secondary outcomes was higher teacher-reported absence among the intervention group at T2 (intervention group median number of days absent 0, control group median number of days absent 0, ratio of geometric means 1.04, 95% CI 1.00 to 1.09, p = 0.042). Process measures indicated little change in perceived mental health support, quality of relationships, and work-related stress. The average cost of the intervention was £9,103 per school. The study's main limitations were a lack of blinding of research participants and the self-report nature of the outcome measures. In this study, we observed no improvements to teacher or student mental health following the intervention, possibly due to a lack of impact on key drivers of poor mental health within the school environment. Future research should focus on structural and cultural changes to the school environment, which may be more effective at improving teacher and student mental health and well-being. www.isrctn.com ISRCTN95909211.

The Relationship Between Stress and Well-being: The Mediating Roles of Students’ Psychological Flexibility and Loneliness During the Coronavirus Pandemic

Coronavirus (COVID-19) has greatly impacted people‘s lives, including those of students in higher education, who have experienced drastic changes causing high levels of stress and decreased well-being. The relationship between stress and well-being can be viewed through the lens of psychological flexibility and loneliness. Individuals who experience high stress tend to be psychologically inflexible and have avoidant/maladaptive coping strategies. As a result, they are also vulnerable to loneliness, which ultimately results in decreased in well-being. In this study, of 945 student-participants, 43.28% met the criterion for high loneliness, 21.9% reported high perceived stress, 69.8% reflected high psychological inflexibility, and their mean score for well-being was 54.45. Serial mediation analysis found that psychological flexibility and loneliness partially mediate the relationship between stress and well-being. However, stress can affect well-being directly but also indirectly through psychological inflexibility and loneliness. A high level of stress, with a low level of psychological flexibility, results in a high level of loneliness; hence well-being decreases. Interventions promoting psychological flexibility can help individuals adapt and cope with difficult situations during the pandemic.

Life during a pandemic in Australia: wellbeing and social determinants of health

BackgroundThe COVID-19 pandemic has had effects on populations worldwide. The social determinants of health affect an individual's capacity to cope during a crisis which could potentially impact on their wellbeing. The aim of this study was to examine the relationship between wellbeing and the social determinants of health among Australian adults during the COVID-19 pandemic.MethodsA cross-sectional study of adults residing in Australia was conducted using SurveyMonkey (an online survey) between August - October 2020. Participants were recruited via social media. Wellbeing was measured using the 10-item Multicultural Quality of Life Index and social determinants of health were measured using validated tools and investigator developed questions. Data were analysed using SPSS version 25. Inferential statistics, including independent t-test and one-way ANOVA were undertaken. Multiple regression analysis was used to investigate the predictors of wellbeing.ResultsIn total, 1211 responses were received. Females accounted for 80.7% of the responses, men 16.7% and transgender/non-binary 2.6%. The mean age of the respondents was 43 years (SD 14.5). The mean score for total wellbeing was 62.58 (SD 21.22). Housing insecurity (p = 0.000), food insecurity (p = 0.000, social support (p = 0.000) and access to health care (p = 0.000) were all predictors of poor total wellbeing. Being a male (p = .0380) was the only predictor of higher wellbeing.ConclusionsThis study demonstrates that adults in Australia who had poor social support, had difficultly accessing health care, had insecure housing and food insecurity had significantly poorer wellbeing during the COVID-19 pandemic. This study exposes the social determinants of health that are responsible for health and social inequalities. It shows that the COVID-19 pandemic has exacerbated the social vulnerabilities and highlights the need take action on the social determinants of health and inequalities.Key messages The COVID-19 pandemic has further exposed the longstanding health and social inequalities that exist in Australia.Action on social determinants of health is required in a post COVID-19 world to rebuild social protection and safeguard populations from any future public health emergencies.

Cross-sectional associations of schoolchildren’s fruit and vegetable consumption, and meal choices, with their mental well-being: a cross-sectional study

BackgroundPoor mental well-being is a major issue for young people and is likely to have long-term negative consequences. The contribution of nutrition is underexplored. We, therefore, investigated the association between...

Associations between the spiritual well-being (EORTC QLQ-SWB32) and quality of life (EORTC QLQ-C30) of patients receiving palliative care for cancer in Cyprus

BackgroundSpiritual well-being is increasingly investigated in relation to patients’ perceived quality of life and is generally thought as having the potential to support patients with cancer who receive palliative care. Until recently, questionnaires used to assess spiritual well-being were developed mainly in the US. The purpose of this study was to translate and use the EORTC- SWB32, a newly developed tool, validated recently in 4 continents, 14 countries, and in 10 languages, to explore relationships of spiritual well-being with quality of life in patients with cancer.MethodsOne hundred four patients participated in this study with an average age of 59 years. Of those, 79% were dealing with metastatic cancer. Data collection took place in three oncology centers from two large cities in Cyprus. The acceptability of the translated items was tested. Two questionnaires were employed for the assessment of quality of life and spiritual well-being, developed by the same organization: the EORTC QLQ-C30 and the EORTC QLQ-SWB32. The scores for each tool were analyzed separately and correlations between the two measures were explored.ResultsPatients found the items of the SWB32 tool easy to understand and answer. They attested that filling the questionnaire prompted thoughts about their own spirituality. The mean score for Global Spiritual Well-Being was 60.4 (SD = 23.7) and it was associated with the mean scores in the scales “Emotional functioning” and “Cognitive functioning” of the EORTC-QOL-C30 (0.42 and 0.40 respectively, p < 0.01). The mean score for the “Relationship with God” scale (74.9, SD = 29.7) reported by the Cypriot patients is high and compatible with the homogenous spiritual orientation of the island’s population.ConclusionsAll subscales of the SWB32 tool demonstrated good internal consistency in this study. Significant associations were observed between dimensions of quality of life and spiritual well-being. Additionally, the participants found the items easy to answer consistent with the tool’s suggested clinical utility which lays the ground for the application of targeted interventions to enhance spiritual well-being.

Well-Being of Healthcare Workers and the General Public during the COVID-19 Pandemic in Vietnam: An Online Survey.

The COVID-19 pandemic and associated restrictive measures implemented may considerably affect people’s lives. This study aimed to assess the well-being of Vietnamese people after COVID-19 lockdown measures were lifted and life gradually returned to normal. An online survey was organized from 21 to 25 April 2020 among Vietnamese residents aged 18 and over. The survey was launched by the Hue University of Medicine and Pharmacy. The WHO-5 Well-Being Index (scored 0–25) was used to score participants’ well-being. A multivariate logistic regression model was used to determine the predictors of well-being. A total of 1922 responses were analyzed (mean age: 31 years; 30.5% male; 88.2% health professionals or students in the health sector). The mean well-being score was 17.35 ± 4.97. Determinants of a high well-being score (≥13) included older age, eating healthy food, practicing physical exercise, working from home, and adhering to the COVID-19 preventive measures. Female participants, persons worried about their relatives’ health, and smokers were more likely to have a low well-being score. In conclusion, after the lockdown measures were lifted, the Vietnamese have people continued to follow COVID-19 preventive measures, and most of them scored high on the well-being scale. Waiting to achieve large-scale COVID-19 vaccine coverage, promoting preventive COVID-19 measures remains important, together with strategies to guarantee the well-being of the Vietnamese people.

Restoring and preserving capacity of self-affirmation for well-being in Indian adults with non-clinical depressive tendencies.

Although self-affirmation has been reported to enhance well-being and other positive life outcomes in normal adults, little is known about its capacity to restore and preserve well-being in adults with depressive tendencies. The current study attempts to expound the restoring and preserving capacity of self-affirmation for well-being in Indian adults with non-clinical depressive tendencies. The study used a sequential research design. Eighty participants (22-27 years) with depressive tendencies were chosen through purposive sampling and were randomly assigned equally to the experimental and control conditions. Their depressive tendencies and well-being were measured through standard scales at three intervals: pre-intervention, post-intervention and follow-up. The results revealed significant restoring and preserving capacity of self-affirmation for the well-being of the experimental group participants as compared to the control group. The main effects of conditions (experimental, control) and treatment intervals (pre, post, follow-up) were significant along with the interaction effects of conditions × treatment intervals. The significant differences in the mean well-being scores for pre-intervention, post-intervention and follow-up points of time showed the restoring and preserving capacity of self-affirmation intervention. The findings showed that self-affirmation helps to restore well-being as well as preserve it after a significant gap, which is evident in higher well-being mean scores of the experimental group taken at post-intervention and follow-up intervals. The positive effects of self-affirmation on well-being may have remained active even after the cessation of the intervention due to the underlying mechanisms of enhanced self-worth, positive values, inner strengths, positive attributions and interpersonal relationships.

Spiritual wellbeing and depression for pregnant mothers in Covid-19 crisis

Background: Women with high-risk pregnancies experience changes in their personal, family, and social lives that can affect their quality of life and depression. Pregnancy, along with other predisposing factors, can cause or exacerbate depression. Eventually, 15% of depressed people commit suicide. The purpose of this research was to see how COVID-19 affected the condition of pregnancy (high risk or normal), as well as well-being and depressive symptoms in pregnant women. Methods: This is an analytical case–control analysis that included 500 pregnant women (250 in the case group and 250 in the control group) who were pregnant during the COVID-19 timeframe for health care during pregnancy. The samples were chosen at random and then grouped into two categories based on the definitions of high-risk pregnancy and normal pregnancy: normal pregnancy (control group) and high-risk pregnancy (case group). A three-part questionnaire with demographic features, the Paloutzian and Ellison Religious Well-Being Questionnaire, and the Depression, Anxiety, and Stress Scale-42 Depression Inventory were used to gather data. Results: According to the findings of this report, the mean score of religious well-being of pregnant mothers with high-risk pregnancies was lower than that of pregnant women with average pregnancies, as were the mean scores of depression. The distinction between a normal pregnancy and a high-risk pregnancy is important. Furthermore, the Pearson correlation coefficient test revealed a strong association between psychological well-being and depression in all types of mothers with high-risk and average pregnancies (r = −0.7) (P = 0.001). Conclusion: Pregnant women with high-risk pregnancies have less psychological well-being than pregnant women with regular pregnancies. Furthermore, these mothers have a greater risk of depression than pregnant women with normal pregnancies.

The Impact of Transitions Related to COVID-19 on Pharmacy Student Well-being

Objective. To characterize the impact of COVID-19 transitions on first professional year (P1) students' domain-specific and overall well-being.Methods. All P1 students (N=74) enrolled at one college of pharmacy self-reported their career, community, financial, physical, social, and overall well-being on a weekly basis from January 6 through April 27, 2020. Parametric statistical tests and effect sizes were used to compare well-being scores pre-transition and post-transition and to compare well-being scores to a previous cohort of P1 students.Results. Mean well-being scores decreased when comparing pre-transition vs post-transition scores, with effect sizes ranging from dav=.16 for financial well-being to dav=.84 for social well-being. The average percent of students that reported struggling increased by 86.1% (16.8% vs 31.2%) post-transition, and the average percent of students that reported suffering post-transition was 351% higher (1.3% vs 6%) than pre-transition.Conclusion. Pharmacy students' domain specific and overall well-being significantly decreased with COVID-19-related transitions. The percentage of students reporting struggling or suffering significantly increased post-transition.

The association of psychological well-being and fertility intention in parents of children with intellectual disability: A foundation for reproductive education.

INTRODUCTION:Childbearing is an important event in a couple's life. The parents might have children with disability that affected on their well-being after the children's birth. Well-being considered as an important aspect of a couple's quality of life which may alter the future of their fertility. The present study was conducted to the association of psychological well-being and fertility intention in parents with educable intellectually disabled children.METHODS:The study was a cross-sectional descriptive research conducted on parents of children with intellectual disability (n = 386). Parents were selected randomly of schools of exceptional education and welfare. The data were collected using Ryff's scale of psychological well-being, demographic information, and fertility intention questionnaire. Data were analyzed using descriptive and analytical tests including independent t-test, Chi-square test, Mann–Whitney U-test, and Logistic regression.RESULTS:The majority of parents (83.9%) reported the negative infertility intention. Despite the mean score of well-being in parents without fertility intention (75.71 ± 11.67) was lower than parents with fertility intention (76.90 ± 11.27), the difference was not statistically significant (P > 0.05). The logistic regression analysis indicated that the parents' age and number of children with intellectual disability were predictors of fertility intention (P < 0.05), and their increase decreased the fertility intention.CONCLUSION:It seems that the lack of difference in psychological well-being scores between the two groups of parents might be due to the equal severity of disability in children. The results also indicated parents' age and the number of children correlated with fertility intention. The findings can be used to advance counseling programs in the field of healthy reproduction for this group of parents.

Acute toxicity and health-related quality of life after accelerated whole breast irradiation in 5 fractions with simultaneous integrated boost

IntroductionAcceleration of radiotherapy in 5 fractions for breast cancer can reduce the burden of treatment. We report on acute toxicity after whole-breast irradiation with a simultaneous integrated boost in 5 fractions over 10–12 days. Material and methodsAcute toxicity and health-related quality of life (HRQoL) of 200 patients, randomized between a 15- or 5-fractions schedule, were collected, using the CTCAE toxicity scoring system, the Multidimensional Fatigue Inventory, EORTC QLQ-C30 and BR23 and the BREAST-Q questionnaire. The prescribed dose to the breast was either 15∗2.67 Gy (40.05 Gy) or 5∗5.7 Gy (28.5 Gy). 90% of patients received a SIB to a cumulative dose of 46.8 Gy (15∗3.12 Gy) or 31 Gy (5∗6.2 Gy). ResultsPhysician-assessed toxicity was lower for the 5-fractions group. A significant difference was observed for breast pain (p = 0.002), fatigue (p < 0.0001), breast edema (p = 0.001) and dermatitis (p = 0.003). Patients treated in 5 fractions reported better mean HRQoL scores for breast symptoms (p = 0.001) and physical well-being (p = 0.001). A clinically important deterioration in HRQoL of 10 points or more was also less frequently observed in the latter group for physical functioning (p = 0.0005), social functioning (p = 0.0007), fatigue (p = 0.003), breast symptoms (p = 0.0002) and physical well-being (p = 0.002). ConclusionIn this single institute study, acute toxicity of accelerated breast radiotherapy in 5 fractions over 10–12 days seems to compare favourably to hypofractionated breast radiotherapy in 15 fractions. Less breast edema, dermatitis, desquamation, breast pain and fatigue are seen. Social and physical functioning are also less disturbed and patients have a better future perspective.

Comparison of Outcomes and Quality-of-Life Measures Following Haploidentical Vs. Matched Related/Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Background: Haploidentical (haplo) transplantation using post-transplant cyclophosphamide (Cy) based GVHD prophylaxis is a well-established alternative donor approach for allogeneic hematopoietic cell transplantation (HCT). Although outcomes from haplo HCT have been compared to matched related (MRD) and unrelated donor (MUD) allo HCT, quality-of-life (QOL) recovery between these transplant modalities has not been described. We hypothesized that post-transplant QOL is similar between Haplo and MRD/MUD grafts. A single-institution, retrospective cohort study was therefore conducted to compare outcomes including QOL between these groups. Methods: From May 2014 through December 2019, 90 haplo, 102 MRD and 229 MUD adult 1st allo HCTs were performed. Myeloablative conditioning (MAC) for haplo grafts (n=35) included fludarabine (Flu)/ total body irradiation (TBI) and reduced-intensity conditioning (RIC) haplo transplants (n=55) included Flu/Cy/TBI. QOL was assessed prior to transplant and at days +100 and +180 by the FACT-BMT which consisted of the following subdomains: "Physical well-being," "Social well-being," "Emotional well-being," "Functional well-being," "Additional concerns," and sum of all these subdomains as "Total score." Outcomes were estimated and compared with the Kaplan-Meier and log-rank test or cumulative incidence and Gray test. FACT-BMT scores were compared with repeated measures analysis of variance. Results: Patient and transplant characteristics were comparable among the donor sources except for higher median age at HCT in MUD transplants, and haplo grafts were more commonly used non-Caucasians, used RIC regimens and bone marrow grafts (Table 1). Median transplant hospital length of stay was longer for haplo vs. MRD vs. MUD grafts (31 vs.25 vs. 25 days, p&amp;lt;0.001) with longer median time until neutrophil and platelet recovery for haplo compared to MRD and MUD grafts (20 vs. 14 vs. 15 days, p&amp;lt;0.001, and 31 vs. 21 vs. 22 days, p&amp;lt;0.001, respectively). MAC haplo HCT had a higher incidence of CMV (p=0.05) and other infections (p=0.003), but no difference in other outcomes compared to MRD/MUD grafts, including all of the QOL domains. The mean Total scores from baseline to day +180 for haplo HCT were 157-157, MRD 153-166, and MUD HCT 152-163. RIC haplo HCT was associated with higher incidences of infections (p&amp;lt;0.001) and relapse mortality (p=0.04), but lower NRM (p=0.008) and no differences in other outcomes. When comparing RIC haplo to MUD transplants there was significantly better Emotional well-being (p=0.008) and Functional well-being (p=0.011) at day+180; respective mean emotional well-being score for haplo 19-23 and MUD 16-19; mean functional well-being score for haplo 19-24 and MRD 19-19 (Figures 1a and 1b). No difference for the other QOL measures were found; the mean Total scores from baseline to day +180 for haplo HCT were 155-180, and MUD HCT were 150-158 (p=0.25). Discussion: Among MAC recipients, we observed no differences in total FACT QOL scores and individual domains among haplo, MRD and MUD HCT recipients through 6 months post-HCT. After RIC HCT, haplo recipients reported better Emotional and Functional well-being compared to those receiving a MUD graft, although Total FACT score and other QOL domains were comparable through 6 months. Future strategies to lessen infectious complications and relapse may further improve QOL outcomes. Interrogation of QOL among disease specific groups may also elucidate whether additional benefits exist between these different transplant modalities. Disclosures Gerds: Sierra Oncology: Research Funding; Gilead Sciences: Research Funding; Celgene: Consultancy, Research Funding; Imago Biosciences: Research Funding; Roche/Genentech: Research Funding; Incyte Corporation: Consultancy, Research Funding; CTI Biopharma: Consultancy, Research Funding; Apexx Oncology: Consultancy; AstraZeneca/MedImmune: Consultancy; Pfizer: Research Funding. Hamilton:Syndax Pharmaceuticals: Consultancy, Honoraria. Majhail:Nkarta Therapeutics: Honoraria; Incyte: Honoraria; Mallinckrodt: Honoraria; Anthem, Inc.: Consultancy.

The Impact of the COVID-19 Quarantine on Sexual Life in Italy

ObjectiveThe aim of the study is to evaluate how individual and couple's sexuality had changed during the COVID-19 pandemic-related quarantine. MethodsA quantitative correlational research study was conducted, using a web-based survey. ResultsAbout 1576 participants were involved: 1018 women (64.6%) and 558 men (35.4%). A significant decline in the mean well-being scores during the quarantine, compared to before, was reported. A positive correlation between the well-being scores and the number of sexual intercourse (SI) before and during the quarantine was found. The mean number of SI decreased significantly during the quarantine. The main reasons were: poor privacy (43.2%) and lack of psychological stimuli (40.9%). About 1124 respondents (71.3%) did not report sexual desire (SD) reduction. A positive association between SD and SI during the quarantine was found. About 61.2% did not report autoerotism reduction. In those who reported decreased masturbation activity, the main causes were poor privacy (46.4%) and lack of desire (34.7%). We found that men presented lower SD during the quarantine, than women (P < 0.01). ConclusionPotentially, the more time available might lead couples to reconnect at an intimate level and to improve their sexuality. However, the majority of quarantined participants experienced reduced number of SI per week, with poor household privacy and lack of psychological stimuli as cited causes, even as a majority did not report reduced autoeroticism.

Identifying characteristics of high-poverty counties in the United States with high well-being: an observational cross-sectional study

ObjectiveTo identify county characteristics associated with high versus low well-being among high-poverty counties.DesignObservational cross-sectional study at the county level to investigate the associations of 29 county characteristics with the odds...

Aging Anxiety and Subjective Well-being of Middle-aged Women: Mediating Effects of Positive Thinking and Social Support

Objectives This study aims to verify the mediating effects of positive thinking and social support on the relation between aging anxiety and subjective well-being of middle-aged women. Methods The subjects of this study were middle-aged women aged 40 to 59, who were members of the online research panel, and a total of 142 data was used for the final analysis. The data were analyzed using the descriptive statistics, Pearson’s correlation coefficient, multiple regression analysis and Sobel test by SPSS Statistics 22.0. Results The mean score of subjective well-being was 3.30. The subjective well-being showed the significantly negative correlation with aging anxiety (r = -0.62, p< 0.001) while it showed the positive correlations with positive thinking (r = 0.82, p< 0.001) and social support (r = 0.63, p< 0.001). In the relation between aging anxiety and subjective well-being, positive thinking and social support were the significant mediating variables. Conclusions Nursing intervention is needed to help build relationships by accepting and adapting aging through positive thinking and strengthening social support networks. Based on these findings, this study will be used as basic data for developing integrated nursing intervention programs to promote well-being of middle-aged women. Key words: Aging anxiety, Positive thinking, Social support, Subjective well-being, Middle-aged women

Psychosocial Adjustment to Illness and Its Relationship with Spiritual Wellbeing in Iranian Cancer Patients.

Background The aim of this study was to investigate the psychosocial adjustment to illness and its relation with spiritual health in cancer patients. Methods This study was conducted in 2019 in Iran. It was a descriptive study with a sample of 124 cancer patients. Data were collected using two questionnaires of the psychosocial adjustment to illness scale (PAIS) with 46 questions and the Paloutzian and Ellison spiritual health scale with 20 questions. Results The mean age of the participants in this study was 52.4 ± 13.2 (range 18 to 87 years). The mean months of life with cancer were 16.5 months. The mean score of psychosocial adjustment to illness was 30.7 ± 15.5. The mean score of spiritual wellbeing in the studied patients was 71.4 ± 17.1. The results of the Pearson correlation test showed a significant inverse relationship between the mean score of psychosocial adjustment to illness and the mean score of spiritual wellbeing (p > 0.001, rr = −.355). Conclusion Cancer patients in this study had relatively good psychosocial adjustment with their illness. Spiritual wellbeing can increase psychosocial adjustment to illness in this group of patients.

Abstract B035: Health-related quality of life among Detroit lung cancer survivors: Findings from the Detroit ROCS studies

Abstract Background: Lung cancer continues to cause more deaths than other cancers, with mortality among African Americans higher than among whites. Despite this, research on the psychosocial aspects of lung cancer patients' quality of life lags behind that of other cancer types, such as breast or prostate. The Detroit Research on Cancer Survivors (ROCS) studies follow the experience of cancer survivors, including lung cancer patients, in Detroit, MI. The Detroit ROCS studies include the pilot study of whites and African Americans, and the ongoing study of African Americans only. Methods: Participants in the Detroit ROCS studies complete the Functional Assessment in Cancer Therapy (FACT) instrument to evaluate their health-related quality of life (QOL). FACT scores are derived from subscores evaluating physical, emotional, social, and functional well-being. Higher scores indicate better QOL. In addition, participants are asked to provide basic demographic information, health history, family history of cancer, and exposure history. Data related to their cancer diagnosis and census tract are gathered via the Metropolitan Detroit Cancer Surveillance System. We examined preliminary data collected from 227 (131 African American and 96 white) lung cancer survivors to assess racial differences in self-reported aspects of well-being. We compared descriptive characteristics using Pearson's Chi-square and Wilcoxon rank sum tests. We modeled adjusted mean well-being subscores using a general linear model. Results: The mean age of African American participants was 61.9 (SD=7.6) and the mean age of whites was 62.9 (SD=8.9). Among African American participants, 40.5% were male; of white participants, 45.8% were male. The distributions of age and sex did not differ significantly between groups. African American participants were less likely to have any college education (p=0.0480), and more likely to live in a census tract with at least 20% poverty (p&amp;lt;0.0001). In a general linear model adjusted for age, sex, cancer stage, and time from diagnosis to interview, race did not predict differences in mean physical and functional well-being subscores. Race significantly predicted differences in adjusted mean emotional and social well-being scores (p=0.0379 and p=0.0466, respectively). The estimated adjusted mean emotional well-being subscore was higher among African Americans than among whites, while the estimated adjusted mean social well-being score was higher among whites. Conclusions: While functional and physical well-being outcomes are similar for African American and white patients after a lung cancer diagnosis, emotional and social well-being outcomes diverge by race. These measures reflect disparities in QOL among lung cancer patients, whose QOL is minimally studied compared to survivors of cancers with lower mortality rates. Future analyses will identify factors influencing this disparity in emotional and social well-being, and describe additional determinants contributing to the QOL of lung cancer survivors. Citation Format: Julia Mantey, Angela Wenzlaff, Jennifer Beebe-Dimmer, Terrance Albrecht, Ann G. Schwartz. Health-related quality of life among Detroit lung cancer survivors: Findings from the Detroit ROCS studies [abstract]. In: Proceedings of the Eleventh AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2018 Nov 2-5; New Orleans, LA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl):Abstract nr B035.

0837 Well-Being Predicts Sleep Disturbance in a Prospective Cohort of Older Adults

Abstract Introduction Lower well-being negatively impacts health among older adults. Optimal sleep - a determinant of health - has been associated with higher well-being. Several domains of well-being, e.g., mindfulness and purpose in life have been shown to improve sleep. But, whether well-being impacts sleep remains unclear. This study examined associations between well-being and sleep duration, sleep quality, and incident insomnia symptoms among a nationally representative sample of older US adults. Methods This study analyzed data from the 2011-2013 National Health and Aging Trends Study (NHATS), a longitudinal, annual survey of community-dwelling Medicare beneficiaries. The exposure, a validated scale of well-being used questions on purpose, emotion, and self-satisfaction and divided responses into quartiles. Sleep outcomes included sleep duration, sleep quality, and insomnia symptoms. Unadjusted and adjusted linear and logistic regression models examined relationships between the health characteristics and well-being score in 2012 and sleep outcomes in 2013. Covariates included demographics and health characteristics. Results Half of study participants (n=2,000) were women. The mean sleep duration was 7.2 and 7.3 (standard error(SE) ±0.1) for men and women. Poor sleep quality was reported by 30% of subjects and more frequently among Hispanic subjects, older adults, and those with less education. The mean well-being score was 17.2 (SE ±0.07). Higher well-being scores correlated with male gender, younger age, higher education, marriage, and increased physical activity. Well-being scores in the 2nd - 4th quartile had lower odds of poor sleep quality (4th quartile adjusted odd ratio 0.24 (95% CI 0.15, 0.38). The highest well-being quartile had a 4-fold lower incidence of insomnia symptoms. Well-being scores were not associated with sleep duration Conclusion Higher well-being may protect older adults against the development of insomnia and poor sleep quality. Strategies to improve well-being could offer an innovative way to improve the health of older Americans though better sleep. Support none

Desire for parenthood at the time of COVID-19 pandemic: an insight into the Italian situation

Purpose: To evaluate the impact of the COVID-19 pandemic lifestyle change on couples of reproductive age and on their desire for parenthood.Materials and methods: A quantitative correlational research study, based on a web survey, was conducted among Italian men and women in heterosexual stable relationships, aged between 18 and 46 years. The self-administered Italian version questionnaire was created using Google Forms and posted on chats and social networks.The mood of participants before and during the quarantine was assessed using a scale from 1 to 10 (1 = no wellbeing; 10 = total wellbeing). Couples’ quality of life and their reproductive desire were evaluated.Results: 1482 respondents were included: 944 women (63.7%) and 538 men (36.3%). A significant trend toward reduced mean wellbeing scores during the quarantine, compared to before, was found (p < .01). From 18.1% participants who were planning to have a child before the pandemic, 37.3% abandoned the intention, related to worries of future economic difficulties (58%) and consequences on pregnancy (58%). Of 81.9% who did not intend to conceive, 11.5% revealed a desire for parenthood during quarantine than before (p < .01), related to will for change (50%) and need for positivity (40%). 4.3% of these actually tried to get pregnant. Stratifying by age, a trend toward older ages was found in the desire for parenthood before and during the COVID-19 pandemic (p < .05).Conclusions: COVID-19 pandemic is impacting on the desire for parenthood. It is unknown whether these findings will result in a substantial modification of birth rate in the near future.