Mean Psoriasis Area And Severity Index Score Research Articles

Dead sea bath salt for the treatment of psoriasis vulgaris: a double‐blind controlled study

AbstractBack‐ground The beneficial effect of the Dead Sea (DS) area in psoriasis is attributed in part to the DS water, which has a high content of minerals,Aim The aim of the study was 10 evaluate the sole therapeutic effect of DS salt in psoriasis.Patients and Methods Thirty patients wild psoriasis vulgaris, involving >15% body area, were included in the study, which was conducted in a double‐blind controlled manner. Treatment consisted of once daily baths, heated lo 35°C, of 20 min duration, for 3 weeks, of cither DS bath salt (group I) or common salt (group II). Clinical evaluation was based on Psoriasis Area and Severity Index (PASI) score determination before and after treatmentResults Twenty‐five patients 113 in group 1 and I 2 in group II) terminated the treatment protocol. In both groups, treated by US hath salt and common salt, respectively, the mean PASI score before treatment (18.6, ± 9.4 and 15.7 ± 7.1. respectively) decreased significantly al the end of the treatment (11.4 ± 6.1 and 11.4± 6.6, respectively). The mean percentage reduction of PASI score at the end of the treatment regimen, was higher in patients treated with IDS bath salt (34.8%) compared to patients treated with common salt (27.5%) (P > 0.05). The mean percentage reduction a month after termination of the treatment protocol was higher in patients treated with DS hath salt (43.6%) than in those treated with common salt (24%) (P > 0.05).Conclusions The present study implies a beneficial effect to bathing wish either DS hath salt or common salt as a sole therapy for psoriasis vulgaris. However, we observed an enhanced beneficial effect of DS hath salt compared to common salt.

Dead sea bath salt for the treatment of psoriasis vulgaris: a double-blind controlled study

Background The beneficial effect of the Dead Sea (DS) area in psoriasis is attributed in part to the DS water, which has a high content of minerals.Aim The aim of the study was to evaluate the sole therapeutic effect of DS salt in psoriasis.Patients and Methods Thirty patients with psoriasis vulgaris, involving >15% body area, were included in the study, which was conducted in a double-blind controlled manner. Treatment consisted of once daily baths, heated to 35°C, of 20 min duration, for 3 weeks, of either DS bath salt (group I) or common salt (group II). Clinical evaluation was based on Psoriasis Area and Severity Index (PASI) score determination before and after treatment.Results Twenty-five patients (13 in group I and 12 in group II) terminated the treatment protocol. In both groups, treated by DS bath salt and common salt, respectively, the mean PASI score before treatment (18.6±9.4 and 15.7±7.1, respectively) decreased significantly at the end of the treatment (11.4±6.1 and 11.4±6.6, respectively). The mean percentage reduction of PASI score at the end of the treatment regimen, was higher in patients treated with DS bath salt (34.8%) compared to patients treated with common salt (27.5%) (P>0.05). The mean percentage reduction a month after termination of the treatment protocol was higher in patients treated with DS bath salt (43.6%) than in those treated with common salt (24%) (P>0.05).Conclusions The present study implies a beneficial effect to bathing with either DS bath salt or common salt as a sole therapy for psoriasis vulgaris. However, we observed an enhanced beneficial effect of DS bath salt compared to common salt.

The effect bathing in a thermal lagoon in Iceland has on psoriasis. A preliminary study

AbstractObjective To investigate if bathing in a unique thermal lagoon in Iceland has a therapeutic effect on psoriasis.Design An open study where twenty‐seven psoriasis patients bathed for three weeks in the lagoon. Psoriasis Area and Severity Index (PASI) was used to evaluate the severity of the disease before during and after bathing.Results The mean PASI score decreased from 16.1 to 8.1 (p= 0.01). The PASI score decreased most in the first week. The area of the lesions did not diminish but scaling erythema and infiltration decreased. Only very limited UV‐radiation was observed during the bathing period.Conclusions Bathing in the lagoon has a favourable effect on psoriasis although in some cases it may not be sufficient as a single treatment. Further studies over longer period are needed.