Introduction. In general, it is equally important in dentistry to be able to examine the occlusion and to register it, store and transmit information from oral cavity. The aim of the study. Clinical and laboratory analysis of inter-maxillary relationship formation efficiency in patients with partial defects of dentition in the position of maximum intercuspation of jaws by means of different bite registration materials selected. Materials and methods. Examination of 10 patients (5 women, 5 men) aged 27 to 59 years was conducted. Upon receipt of teeth impressions of both jaws, and fabrication of their cast models, intermaxillary relationship in the position of maximum intercuspation (MIC) of the jaws with the help of selected registration materials (Consiflex (Ukraine), metallized wax (Germany), Futar D (Germany)) was determined. Results. During clinical examination of 10 patients it was found that when using Futar D registration material, biometric deviation of markers (BDM) index in the region of teeth 16-46 was (0.03±0.03) mm, 26-36 - (0.035±0.03) mm (p-value more than 0.75). At the same time, BDM index in the region of teeth 13-44 reached (0.05±0.03) mm, and teeth 23-34 demonstrated values (0.04±0.03) mm (p-value more than 0.5). Studies in the region of teeth 21-31 established BDM value within (0.01±0.03) mm. Application of Consiflex as a registration material demonstrated that BDM index in the region of molars on the right was (0.065±0.04) mm, on the left it reached (0.05±0.05) mm (p-value more than 0.49). According to the results of the study conducted, this index in the region of upper incisors - lower premolars on the right reached (0.08±0.03) mm, being (0.07±0.03) mm (p-value more than 0.53) between these pairs of teeth-antagonists on the left side. BDM index in the region of teeth 21-31 was determined in the range of (0.03±0.05) mm. Application of metallized wax as a registration material demonstrated that BDM index in the region of molars on the right was (0.085±0.02) mm, on the left it reached (0.07±0.03) mm (p-value more than 0.28). According to the results of the study conducted, this index in the region of upper incisors - lower premolars on the right reached (0.10±0.03) mm, being (0.08±0.03) mm (p-value more than 0.21) between these pairs of teeth-antagonists on the left side. BDM index in the region of teeth 21-31 was determined in the range of (0.04±0.05) mm. During laboratory study of cast models of 10 patients in the MIC position, it was found that when using Futar D registration material, BDM index in the region of teeth 16-46 was (0.03±0.03) mm, teeth 26-36 - (0.35±0.03) mm (p-value more than 0.75). At the same time, this index in the region of teeth 13-44 was (0.055±0.04) mm, teeth 23-34 - (0.045±0.04) mm (p-value more than 0.59), respectively. In the region of teeth 21-31, its value reached (0.01±0.03) mm. Application of Consiflex demonstrated that BDM index on cast models in the region of molars on the right was (0.07±0.05) mm, on the left it reached (0.55±0.055) mm (p-value more than 0.53). According to the results of the studies, this index in the region of upper incisors - lower premolars on the right reached (0.09±0.04) mm, being (0.08±0.04) mm (p-value more than 0.59) between these pairs of teeth-antagonists on the left side. BDM index in the region of teeth 21-31 was determined in the range of (0.03±0.05) mm. Application of metallized wax as a registration material demonstrated that BDM index on cast models in the region of molars on the right was (0.095±0.03) mm, on the left it reached (0.08±0.03) mm (p-value more than 0.23). According to the results of studies, this index in the region of upper incisors - lower premolars on the right reached (0.11±0.03) mm, being (0.09±0.04) mm (p > 0.23) between these pairs of teeth-antagonists on the left side. BDM index in the region of teeth 21-31 reached (0.045±0.05) mm. Conclusions. Application of Futar D demonstrates lower optimum (0.00-0.08 mm) of differences between biometric deviation of markers indices, suggesting better complementarity during maximum intercuspation registration of this material in comparison with Consiflex (0.00-0.11 mm) and metallized wax (0.00-0.13 mm).