Background: Among tooth anomalies, missing teeth is one of the most frequent, and it can be related to different therapeutical sets of problems. Often, an integrated approach that interests both orthodontists and prosthodontists is necessary, and in some cases also the periodontists. Methods: In this paper the authors report a clinical case of a 14-year-old patient, affected by maxillary bilateral incisors agenesis, molar bilateral II class and deep bite, treated in the Department of Orthodontics and Pedodontics of the University of Messina. The orthodontic treatment target was the distal movement of the maxillary molar, and the recovery of the space necessary for the prosthetic restoration of the missing lateral incisor. Maxillary molars distal movement was performed with a Distal Jet apparatus, skeletally supported by two miniscrews (Distal-Screw, American Orthodontics, Sheboygan, WI, USA). After molar relationship correction, a multi-bracket bimaxillary orthodontic appliance was bonded using Empower Brackets (American Orthodontics, Sheboygan, WI, USA). At the end of orthodontic treatment a Maryland bridge, bonded on the central incisors and cuspids, was used in order to maintain the space necessary for the insertion of dental implants in the region of 1.2 and 2.2 Results: A class II molar relationship was corrected, with an improvement of the deep bite, and the space necessary for implant insertion was recovered Conclusion: A skeletally supported Distal Jet was efficient for molar distalization, with the advantage of not having any loss of anchorage in the anterior part of the dental arch. This apparatus does not need patient compliance, have favorable aesthetics and also give the possibility to perform asymmetric activations.