Mathematics, being a highly advanced field of Science, is closely linked to success in modern society as it is considered a necessary skill. This study sought to determine the extent to which attitudes, parental influence, and self-efficacy are factors that affect learners' performance in Mathematics; to detect learners' Mathematics performance throughout the First Quarter of the School Year 2023 - 2024; to determine the significance of the relationships between factors affecting performance in Mathematics and learners’ First Quarter Mathematics performance of the School Year 2023 -2024; and to find out which of the independent variable/s singly or in combination best predict/s performance in Mathematics; and also to create an intervention plan based on the study's findings. There were one hundred seventy-six (176) Grade 6 learners from the District of Laguindingan schools, Division of Misamis Oriental that participated in the survey. The instrument used was adapted and modified from Peteros et al. (2019), Silao (2018), and Dagdag et al. (2020). The data gathered were analyzed using frequency, percentage, mean, standard deviation, Pearson Moment Correlation, and multiple regression analysis. The findings of the study showed that attitude toward Mathematics is the best indicator of Mathematics performance. The researcher recommends that the DepEd officials, administrators, parents, and stakeholders work together to deal with learners' Mathematics performance. Teachers may conduct parent workshops or training sessions and counseling on how to set realistic, achievable goals based on the child's capabilities.