A blocking quadruple (BQ) is a quadruple of vertices of a graph such that any two vertices of the quadruple either miss (have no neighbours on) some path connecting the remaining two vertices of the quadruple, or are connected by some path missed by the remaining two vertices. This is akin to the notion of asteroidal triple used in the classical characterization of interval graphs by Lekkerkerker and Boland [Klee, V., What are the intersection graphs of arcs in a circle?, American Mathematical Monthly 76 (1976), pp. 810–813.].In this note, we first observe that blocking quadruples are obstructions for circular-arc graphs. We then focus on chordal graphs, and study the relationship between the structure of chordal graphs and the presence/absence of blocking quadruples.Our contribution is two-fold. Firstly, we provide a forbidden induced subgraph characterization of chordal graphs without blocking quadruples. In particular, we observe that all the forbidden subgraphs are variants of the subgraphs forbidden for interval graphs [Klee, V., What are the intersection graphs of arcs in a circle?, American Mathematical Monthly 76 (1976), pp. 810–813.]. Secondly, we show that the absence of blocking quadruples is sufficient to guarantee that a chordal graph with no independent set of size five is a circular-arc graph. In our proof we use a novel geometric approach, constructing a circular-arc representation by traversing around a carefully chosen clique tree.