AbstractThe current study examined multi-trajectories of aggression, hyperactivity/inattention and anxious/depressed problems, along with associated risk factors for trajectory group membership, using a person-centred approach. The sample included 2,857 children (50.1% males) enrolled in the Chilean Encuesta Longitudinal de la Primera Infancia cohort. Maternal reports using the Child Behaviour Checklist (CBCL) were completed when children were three, five and eleven years old. Information on risk/protective factors was collected using maternal reports and standardised assessments when children were aged three. Group-based multi-trajectory analysis was implemented. Results indicated that a five-group model best fit the data, with co-occurring symptoms across domains for all groups. Risk factors for membership of groups with the most elevated risk profiles included child sex, maternal age, single parent status, and maternal education, whilst children’s receptive language, maternal vocabulary skills, and not having early attendance in the educational system emerged as protective factors. These identified risk factors may be important targets for future intervention programmes in the Chilean context.