Massive Tears Research Articles

Posteroinferior relevant scapular neck offset in reverse shoulder arthroplasty: key player for motion and friction-type impingement in a computer model.

Range of motion (ROM) and prevention of notching remain a challenge for reverse shoulder arthroplasty (RSA). Both may be affected by the morphology of the scapula. The purpose of this study was to define anteroinferior (a) and posteroinferior (p) relevant scapular neck offset (RSNO) and to examine the hypothesis that pRSNO is significantly smaller than aRSNO, and influences rigid body motion (RBM). Adapting glenosphere implantation strategies may therefore be of value. In this computer model study, we used deidentified computed tomographic scans of 22 patients (11 male and 11 female; mean age: 72.9 years) with massive cuff tears without joint space narrowing. Eight RSA glenoid configurations were tested with a constant neck-shaft angle (145°). Two baseplate types (25 mm; 25 + 3 mm lateralized) and 4 glenospheres (GS) (36 mm; 36 +2 mm of eccentricity; 39 mm; 39 + 3 mm) were used. RSNO was defined as the standardized measurement of the horizontal distance from the inferior extent of the GS to the bony margin of the scapula after baseplate positioning (flush to inferior glenoid extent; neutral position: 0° inclination and 0° version-both software computed). There was a highly significant difference between pRSNO and aRSNO for both genders (P<.001). pRSNO was always smaller than aRSNO. pRSNO was strongly correlated with external rotation (ERO: 0.84) and extension (EXT: 0.74) and moderately correlated with global ROM (GROM: 0.68). There was a moderately strong correlation between aRSNO and internal rotation (IRO: 0.69). pRSNO was strongly correlated with aRSNO, EXT, ERO, IRO, adduction (ADD) and GROM (0.82, 0.72, 0,8, 0.71, 0.82, 0.76) in female patients and with EXT and ERO (0.82, 0.89) in male patients. The median pRSNO allowing for at least 45° ERO and 40° EXT was 14.2 mm for men and 13.8 mm for women. For all patients and models, pRSNO ≥14 mm increased EXT, ERO, and GROM significantly compared with pRSNO <14 mm (P<.001). The combination of lateralization and inferior overhang (eccentricity) led to the most significant increase of pRSNO for each GS size (P<.001). This is one of the first RSA modeling studies evaluating nonarthritic glenoids of both genders. The lateral scapular extent to glenoid relationship is asymmetric. pRSNO is always smaller than aRSNO for both genders and was a critical variable for EXT and ERO, demonstrating additional strong correlation with aRSNO, IRO, ADD, and GROM in female patients. pRSNO ≥14 mm was a safe value to prevent friction-type impingement. Combining increased glenosphere size, lateralization, and inferior overhang gives the best results in this computer-simulated setting.

The Arthroscopic Trillat Procedure Is a Valuable and Durable Treatment Option for Recurrent Anterior Instability Associated With Massive Irreparable Cuff Tears

The purpose of the present study is to report the mid- and long-term clinical and radiologic outcomes of the arthroscopic Trillat for the treatment of recurrent anterior instability in patients with chronic massive irreparable rotator cuff tears (MIRCTs) and maintained active shoulder motion where reverse shoulder arthroplasty (RSA) is not indicated. Twenty-one consecutive patients (mean age 61 years) were identified and retrospectively reviewed. All patients had recurrent anterior dislocations and conserved active forward elevation and active external rotation. The MIRCTs included a retracted (stage 3) supraspinatus tear in 14%, a supra- and infraspinatus tear in 76.5%, and a 3-tendon tear in 14%. A closed-wedge osteotomy of the coracoid was performed, and the coracoid was fixed above the subscapularis with a cannulated screw (10 cases) or suture buttons (11 cases). We followed patients with x-rays and computed tomography scan at 6 months, along with Subjective Shoulder Value, visual analog scale, Walch, Constant, and Rowe scores. The mean clinical and radiographic follow-up was 58 months (24-145 months). Overall, 96% (20/21) of the patients had a stable and functional shoulder and were satisfied with the procedure; no patient lost active shoulder motion. The Subjective Shoulder Value increased from 44% (10%-75%) to 94% (80%-100%), P < .001. The Constant and Rowe scores improved from 60 (25-81) to 81 (66-96) and from 54 (35 to 65) to 92 (70-100), respectively (P < .001). Among the 13 patients practicing sports before surgery, 10 (77%) went back to sports. At last follow-up, only 1 patient was revised to RSA. The arthroscopic Trillat procedure is a valuable and durable option for the treatment of recurrent anterior dislocations in older patients with chronic MIRCTs and conserved active shoulder motion. Level IV, therapeutic case series.

Rare case of intra-articular biceps incarceration following traumatic massive rotator cuff tear

Rare case of intra-articular biceps incarceration following traumatic massive rotator cuff tear

A method for the treatment of patients with massive tears of the rotator cuff: a clinical case

Background: Rotator cuff tears are the most common cause of shoulder pain and dysfunction in older patients. Tears with the retraction greater than 5 cm or with the involvement of two and more tendons are considered massive. According to the literature, the incidence of massive injuries of the rotator cuff ranges from 10 to 40%. The formation of massive injuries is a long process leading to a pronounced pain syndrome, loss of function and, as a result, to pseudo-paralysis of the affected limb. There is no consensus concerning the treatment of this category of patients. Conservative methods of treatment are applicable for patients with a low activity. Among the surgical methods of treatment, the preference is given to the proximal capsule reconstruction, subacromial balloon arthroplasty, reverse arthroplasty and muscle-tendon transfers. However, today there is no single tactic for the surgical treatment of patients with massive rotator cuff tears. Clinical case description: We propose a new surgical method for this shoulder joint pathology arthroscopically associated transposition of the tendon of the latissimus dorsi muscle using an autograft of the long peroneal muscle tendon. As an illustration of the new method, we present a successful clinical case of the treatment of a patient with a chronic massive rotator cuff injury of the right shoulder and secondary upper subluxation of the right humerus head. Conclusion: This method allows increasing the efficiency of the treatment of a massive tear of the rotator cuff tendons, restoring the correct biomechanics of the shoulder joint, reducing the pain and restoring the function of the affected limb.

Movement compensation is driven by the deltoid and teres minor muscles following severe rotator cuff tear

BackgroundRotator cuff tears are common in older adults, negatively affecting function. Previous simulation-based studies reported more posterior and superior oriented glenohumeral loading with increased cuff tear severity and task performance, although corresponding muscle compensation strategies are unclear. Our objective is to determine how shoulder muscle forces change with increased rotator cuff tear severity during functional task performance. MethodsEight musculoskeletal models of increasing tear severity were developed to represent no rotator cuff tear to massive three-tendon tears. Simulations were performed using each combination of model and kinematics for five functional tasks. Individual muscle forces were averaged for each task and tear severity, then normalized by the sum of the muscle forces across the shoulder. Forces were compared across tear severity and muscle. FindingsFor muscle force contribution, interactions between tear severity and muscle and a main effect of muscle were seen for all tasks (P < 0.0001). Middle deltoid increased force contribution by >10% in the greatest tear severity model compared to no cuff tear model for all tasks (all P < 0.0001). Teres minor contribution increased by 7.7%, 5.6%, and 11% in the greatest tear severity model compared to the no cuff tear model for forward reach, axilla wash, and upward reach 105° tasks, respectively (all P < 0.0001). InterpretationFunctional tasks elicit compensatory responses from uninjured muscles following severe cuff tears, notably in middle deltoid and teres minor, leading to posterior-superior glenohumeral loading. The muscles are potential targets for strengthening to avoid injury from sustained increased muscle force.

Pre-Operative Corticosteroid Injections And Rate Of Re-Ruptures And Infections In Primary Arthroscopic Rotator Cuff Repair

PURPOSE: The aim of this study was to determine if the re-rupture rate and post-operative infections differed among patients who received a corticosteroid injection (CSI) and those who did not prior to primary arthroscopic rotator cuff repair (RCR). METHODS: Patients who underwent primary RCR by a single surgeon (1999-2020) were included. Demographics included age at the time of surgery, BMI, comorbidities, and the administration of pre-operative CSIs. Tear thickness, size, and RCR integrity were evaluated pre-and post-operatively, by ultrasound or MRI. Infection was identified through clinical diagnosis and post-operative lab work. RESULTS: 154 shoulders underwent primary arthroscopic RCR and were included. 92 patients were in the no injection group including 66 males and 26 females (age 60.7 ± 13.1 years, BMI 27.3 ± 4.8), and 62 patients were in the injection group including 38 males and 24 females (age 58.1 ± 12.3 years, BMI 27.7 ± 4.9). There were no differences in demographics between groups aside from a greater proportion of males in the no injection group (P < 0.001). There were 22 (23.9%) partial and 70 (76.1%) full thickness tears in the no injection group and 18 (29.0%) partial and 4 (71.0%) full thickness tears in the injection group (P > 0.05). Of the full thickness tears in the no injection group, there were 9 (12.9%) small (<1 cm), 12 (17.1%) medium (1-3 cm), 26 (37.1%) large (3-5 cm), and 23 (32.9%) massive tears (>5 cm). Of the full thickness tears in the injection group, there were 7 (15.9%) small, 7 (15.9%) medium, 19 (43.2%) large, and 11 (25.0%) massive tears. There were no differences in primary tear characteristics. No postoperative infections were reported. The average time from pre-operative CSI to surgery was 9.6 ± 22.3 months in the injection group. There were 16 re-ruptures in the no injection group (17.4%) and 11 in the injection group (17.7%) (P > 0.05). The average time to failure was 2.0 ± 3.0 years in the no injection group and 4.6 ± 4.7 years in the injection group (P > 0.05). CONCLUSION: Preoperative CSI did not lead to infections or increased risk of re-rupture following arthroscopic primary RCR in our cohort suggesting this is a viable treatment option in the management of rotator cuff tears without compromising postoperative outcomes.

Expression and distribution pattern of aggrecanases and miR-140s in the thickened synovia of shoulder joints in rotator cuff tears: A retrospective observational study.

The rotator cuff (RC) is frequently torn at the enthesis composed of fibrocartilage. We aimed to histopathologically evaluate lining layers and assess the distribution of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)4, ADAMTS5, and microRNA (miR)-140s in the synovia of patients with RC tears. We recruited 51 patients who underwent arthroscopic surgical treatment for full-thickness rotator cuff tears, including 26 patients with < 3 cm tear size (group N) and 25 patients with ≥ 3 cm tear size (group W). Biopsied synovia were analyzed using histological and immunohistological techniques for the presence ADAMTS4 and ADAMTS5. The layers of the synovial lining were morphologically classified into 3 grades according to the synovitis score and staining levels of ADAMTSs. The glenohumeral synovia from 8 patients with recurrent shoulder dislocation (group C) were used as controls. Furthermore, in situ hybridization was performed to evaluate the presence of miR-140s in patients with massive tears and recurrent shoulder dislocation. The staining levels were evaluated and analyzed based on comparison between patient groups and correlation between ADAMTS5 and miR-140s. Histological analysis revealed significant differences between groups W and C. ADAMTS5 and ADAMTS4 were strongly expressed in the synovial lining of patients in group W, and this expression was significantly higher than that in groups C and N. In addition, expression of ADAMTS5 was inversely correlated with that of miR-140-3p. This study showed that synovia from group W had a significantly higher rate of severely thickened areas with strong expression of both aggrecanases. Furthermore, the area with weak expression of miR-140-3p showed strong ADAMTS5 expression.

Management of Massive Rotator Cuff Tears Without Arthropathy.

Arthroplasty is not an optimal treatment for massive rotator cuff tears in patients who are active and without glenohumeral arthritis. Several surgical techniques have been developed for these patients, including arthroscopic rotator cuff repair with single-/double-row repair (with or without interval slides, margin convergence, graft augmentation), graft bridging, superior capsular reconstruction, tuberoplasty, and tendon transfers. Complete, tension-free, anatomic repair is ideal; however, tendon atrophy and retraction associated with massive tears often complicate repairs. All surgical treatments significantly increase patient-reported functional outcomes 1 year after intervention, with many treatments demonstrating improved mid-term and long-term outcomes. [Orthopedics. 2023;46(1):e1-e12.].

Poster 153: Dynamic Radiographic Evaluation of Scapulohumeral Rhythm in Patients with Massive vs Small Rotator Cuff Tears

Objectives:The management of rotator cuff tears varies based on patient age, function, tear size, and chronicity. Treatment of massive tears results in less favorable or predictable outcome, presenting a challenge in determining the optimal intervention. Classification of a tear as “massive” is often based on MRI and confirmed intraoperatively. However, the use of a functional measure of shoulder motion, such as the scapulohumeral rhythm (SHR), offers an alternate, clinically relevant method to help guide diagnosis and surgical management. Defined as the ratio of glenohumeral (GH) to scapulothoracic (ST) motion, SHR is known to be altered in patients with rotator cuff tears. While previously challenging to measure SHR in a clinical setting, a novel technique known as Dynamic Digital Radiography (DDR) provides a safe and cost-effective method to directly compare changes in motion between patients with rotator cuff tears and correlate these changes to tear severity. The purpose of this study was to evaluate patients with massive and small rotator cuff tears using DDR, assessing for differences in SHR and range of motion between the two groups.Methods:Shoulders were prospectively analyzed using DDR via obtaining a series of pulsed radiographs at up to 15 Hz of the joint in motion. Scapulothoracic motion and glenohumeral motion were quantified based on the DDR images (figure 1). Measurements were taken in humeral abduction at 0-30°, 30-60°, 60-90°, and full abduction using the Grashey view. SHR at different points was calculated by dividing the humeral arc of motion by the scapular arc of motion in each of those motion ranges. Pairwise t-tests were performed on the obtained data to compare differences between groups at an α level of 0.05.Results:42 patients with a primary diagnosis of rotator cuff tear matched for age and BMI were analyzed (table 1). Based on clinical presentation and MRI, 29 patients were classified as massive rotator cuff tear (MRCT) and 13 patients were classified as small rotator cuff tear (SRCT). The final angle calculations are displayed in table 2. SRCT patients had a significantly higher average overall SHR of 3.04 ± 1.16 compared to the MRCT SHR of 1.91 ± 0.51 (p=0.003). When analyzed across 30-degree intervals of humeral abduction, MRCT patients had a significantly lower SHR compared to SRCT patients at 30-60° (1.83 ± 0.97 vs 3.39 ± 1.62, p=0.005). MRCT also had a lower SHR between 0-30° (2.63 ± 2.08 vs 4.74 ± 3.83, p=0.08) and 60-90° (2.13± 0.80 vs 2.91 ± 1.41 , p=0.13) of humeral abduction compared to SRCT patients, but these differences were not statistically significant. SHR changes across these intervals of humeral abduction are plotted in figure 2. Scapular range of motion during humeral abduction was lower in SRCT compared to MRCT (29.71 ± 12.91 vs 41.57 ± 10.41, p=0.08). No statistically significant difference was found in humeral range of motion between MRCT (76.02 ± 22.66) and SRCT (80.93 ± 20.71).Conclusions:A dynamic measurement of motion demonstrates that scapulohumeral rhythm is significantly different between patients with small vs. massive rotator cuff tears. Based on DDR analysis, patients had a marked difference in the initiation of motion and through the first 60 degrees of humeral abduction, resulting in a nearly 2x lower SHR in MRCT compared to SRCT. Moreover, evaluation of glenohumeral and scapulothoracic motion during humeral abduction demonstrated that patients with larger tears had an increased reliance on scapular contributions to overall humeral elevation. Dynamic measurement of SHR represents a novel method for evaluating rotator cuff tears, with marked differences noted in the earlier phases of shoulder motion. Further study and validation of the dynamic assessment of SHR has the potential to augment the diagnostic algorithm for rotator cuff tears, and ultimately inform prognostic and functional expectations for both the patient and the physician.Table 1.Patient DemographicsTable 2.Relative contributions by glenohumeral (GH) and scapulotlioracic (ST) joint to shoulder girdle motionFigure 1.Reference lines used for calculation of the humeral and scapular abduction arcs. Measurements were taken in reference to a vertical line. Calculations were made in the neutral position, at initiation of abduction, 30°, 60°, 90° and full abduction.Figure 2.SHR measured at 30-degree intervals of humeral abduction. The * Indicates a statistically significant difference at α = 0.05 in SHR measured between massive rotator cuff tear and small rotator cuff tear patients. P-values from left to right are 0.08 (0-30 °), 0.005 (30-60 °), 0.13 (60-90 °), and 0.003 (total)

Results of arthroscopic rotator cuff repairs in patients with comorbid disability of other extremities

Objectives: We hypothesized that arthroscopic rotator cuff repair improves functional and clinical outcomes in the patients with comorbid disability in the extremities. Materials and Methods: In a retrospective study, data were collected for eleven patients (six males and five females) from a tertiary care hospital from 2010 to 2018. All the patients underwent arthroscopic rotator cuff repair after confirmed clinical and radiological diagnosis. All the patients were operated on by a single surgeon. UCLS scores and ultrasound imaging were used for pre-operative and post-operative clinical and radiological evaluation, respectively. The mean follow-up was of 3 years. Statistical analysis was carried out using SPSS software and statistical significance was considered at P &lt; 0.05. Results: Out of 11 patients, seven patients had massive cuff tears, two patients had medium cuff tears, and two patients had small cuff tears. Out of 11 patients, three patients were contralateral side amputees, four patients were wheelchair-bound due to post-poliomyelitis muscle weakness, one patient had opposite side hand amputation, and three patients had same side hemiplegia secondary to cerebrovascular stroke. The dominant side was involved in eight patients and the non-dominant side was involved in three patients. Functional range of motion, the visual analog scale for pain, and satisfaction and UCLS scores improved significantly after arthroscopic cuff repairs. Ultrasound evaluation after a mean of 14 ± 3 months revealed complete healing in 88% of cases and partial healing in 12% of cases. Conclusion: Arthroscopic rotator cuff repair improves functional and clinical outcomes in patients with comorbid disability in the extremities. Careful and meticulous clinical acumen, surgical planning, technique, and post-operative rehabilitation program are important for excellent outcomes in arthroscopic cuff repairs, especially in these functionally high-demanding patients.

Arthroscopic Extreme Medialized Repair for Massive Rotator Cuff Tear: Resection of Cartilage and Subchondral Bone Over the Top of the Humeral Head

Rotator cuff repair is a widely performed surgery. Its purpose is to improve shoulder function, fix tendons to bones, restore anatomical structure, and prevent the progression of rotator cuff tear arthropathy and associated muscle degeneration. However, in large and massive tears, the tension imposed during repair becomes too high. Medialized repairs have been reported for cases of rotator cuff tear, but they are difficult to perform. We report on ex-medialization that used common portals and instruments to remove the osteochondral and subchondral bone, reduce humeral head volume, and suture the tendon extremely medially. Compared to a common medialized repair, this procedure reduces tension on the rotator cuff to be sutured. The goal of this technique is to restore functional anatomy, reduce the rate of retear, prevent the progression of rotator cuff muscle atrophy and fatty degeneration, and to improve muscle strength by allowing the repair of rotator cuff tears (Goutallier grade 2 or higher) to the humeral head, which have conventionally been challenging.

Mesenchymal Stem Cell Delivery via Topographically Tenoinductive Collagen Biotextile Enhances Regeneration of Segmental Tendon Defects

Background: Successful management of massive rotator cuff (RC) tendon tears represents a treatment challenge because of the limited intrinsic healing capacity of native tendons and the risk of repair failure. Biologic augmentation of massive RC tears utilizing scaffolds—capable of regenerating bulk tendon tissue to achieve a mechanically functional repair—represents an area of increasing clinical interest. Purpose: To investigate the histological and biomechanical outcomes after the use of a novel biologic scaffold fabricated from woven electrochemically aligned collagen (ELAC) threads as a suture-holding, fully load-bearing, defect-bridging scaffold with or without mesenchymal stem cells (MSCs) compared with direct repair in the treatment of critically sized RC defects using a rabbit model. Study Design: Controlled laboratory study. Methods: A total of 34 New Zealand White rabbits underwent iatrogenic creation of a critically sized defect (6 mm) in the infraspinatus tendon of 1 shoulder, with the contralateral shoulder utilized as an intact control. Specimens were divided into 4 groups: (1) gap—negative control without repair; (2) direct repair of the infraspinatus tendon—operative control; (3) tendon repair using ELAC; and (4) tendon repair using ELAC + MSCs. Repair outcomes were assessed at 6 months using micro–computed tomography, biomechanical testing, histology, and immunohistochemistry. Results: Specimens treated with ELAC demonstrated significantly less tendon retraction when compared with the direct repair group specimens (P = .014). ELAC + MSCs possessed comparable biomechanical strength (178 ± 50 N) to intact control shoulders (199 ± 35 N) (P = .554). Histological analyses demonstrated abundant, well-aligned de novo collagen around ELAC threads in both the ELAC and the ELAC + MSC shoulders, with ELAC + MSC specimens demonstrating increased ELAC resorption (7% vs 37%, respectively; P = .002). The presence of extracellular matrix components, collagen type I, and tenomodulin, indicating tendon-like tissue formation, was appreciated in both the ELAC and the ELAC + MSC groups. Conclusion: The application of MSCs to ELAC scaffolds improved biomechanical and histological outcomes when compared with direct repair for the treatment of critically sized defects of the RC in a rabbit model. Clinical Relevance: This study demonstrates the feasibility of repairing segmental tendon defects with a load-bearing, collagen biotextile in an animal model, showing the potential applicability of RC repair supplementation using allogeneic stem cells.

Reverse Total Shoulder Arthroplasty for Treatment of Massive, Irreparable Rotator Cuff Tear

Massive tears of the rotator cuff can result in severe functional deficits due to loss of the axial force couple and effective fulcrum that the intact cuff normally provides. For massive, irreparable rotator cuff tears, especially in the setting of early to moderate degenerative changes, reverse total shoulder arthroplasty functions to modify the center of joint rotation, allowing the deltoid and intact components of the cuff to carry out shoulder function more effectively. Our preferred technique uses a standard open deltopectoral shoulder approach with a 3-dimensional glenoid baseplate model and a 135° prosthesis in an onlay configuration to reduce the risk of scapular notching and increase lateralization of the humerus.

Tendon transfers for massive rotator cuff tears.

Massive rotator cuff tears (MRCTs) present a particular challenge due to high rates of retear that can range from 18 to 94%, failure of healing after repair, and potential for irreparability.Management of MRCTs must take into consideration the patient's characteristics, clinical examamination and expectation, number and quality of muscle tendons units involved.Conservative treatment, arthroscopic long head of the biceps tenotomy, cuff debridement, partial repair, and superior capsule reconstruction are viable solutions to treat selected patients.The goal of tendon transfers is to achieve stable kinematic by restoring rotational strength and force coupling of the shoulder joint.The ideal candidate is a young, motivated patient with small degenerative changes of the glenohumeral joint, a massive irreparable cuff tear, significant atrophy, fatty infiltration, and functional deficit.Patients with posterosuperior massive tears have impaired shoulder function with external rotation weakness and eventually lag sign If the teres minor is affected.Latissimus dorsi transfer is the most used with results lasting for long follow-up and lower Trapezius transfer is becoming a surgical option. For anterosuperior tears, there is still controversial if pectoralis major is the best option when compared to latissimus dorsi although this last has a similar vector force with the supraspinatus tendon.Complications associated with tendon transfers include neurovascular injury, infection, and rupture of the transferred tendon.

3D bioprinting of multilayered scaffolds with spatially differentiated ADMSCs for rotator cuff tendon-to-bone interface regeneration

Regeneration of the gradient structure of the tendon-to-bone interface is still a significant clinical challenge. This study reports a novel therapeutic method combining three-dimensional (3D) bioprinting and melt electrospinning writing techniques to regenerate a functional tendon-to-bone interface. We generated biomimetic multilayered scaffolds with 3D-bioprinted pre-differentiated autologous adipose-derived mesenchymal stem cells (ADMSC), which recapitulated compositional and cellular structures of the interface. The hydrogel-based bioinks offered high cell viability and proliferative capability for rabbit ADMSCs. The hydrogels with pre-differentiated (into tenogenic, chondrogenic, and osteogenic lineages) or undifferentiated rabbit ADMSCs were 3D-bioprinted into zonal-specific constructs to mimic the structure of the tendon-to-bone interface. These scaffolds were tested in a rabbit rotator cuff injury model and the histological, radiological, and biomechanical changes were analyzed. The in vivo studies demonstrated that the scaffold with spatially differentiated autologous ADMSCs had a superior histological score and improved collagen organization when compared to acellular scaffolds and similar T2 value as the normal interface tissue. The biomechanical characterization demonstrated that the application of multilayered scaffolds improved the biomechanical properties of the tendon-to-bone interface at 12 weeks after rotator cuff reconstruction surgery, but the incorporation of autologous ADMSCs within the multilayered scaffolds showed a limited contribution. Thus, our work provides a 3D-bioprinting-based strategy with the application of autologous ADMSCs to reconstruct massive rotator cuff tendon tears.

Survivorship of Reverse Shoulder Arthroplasty According to Indication, Age and Gender.

Background. The indications for reverse shoulder arthroplasty (RSA) have been widely expanded, but only a few studies report the long-term survival of these implants. Our objective was to report the long-term survivorship of a large series of RSAs implanted for different etiologies. Methods. A retrospective multicenter study including all the RSAs was performed in six shoulder-specialized centers with at least 2 years of follow up. We reviewed 1611 RSAs, operated between 1993 and 2010, including 497 cuff-tear arthropathies (CTA), 239 revision RSAs, 188 massive cuff tears (MCT), 185 fracture sequelae (FS), 183 failed previous cuff repairs (FCR), and 142 primary osteoarthritis (POA). The mean follow-up was 5.6 ± 3.9 years (range 2–20). Results. Overall, 266 RSAs (16.5%) had at least one complication leading to 64 reoperations (4.0%) and 110 revision surgeries (6.8%). The most frequent complications were infection (3.8%), instability (2.8%), and humerus-related complications (2.8%). At 10 years, the survival without revision surgery was 91.0% in primary RSAs and 80.9% in revision RSAs for failed arthroplasty (p < 0.001). In the primary RSA group, MCT and FCR led to 10-year survivals for over 95% but fracture sequelae and tumors had the lowest 10-year survivals (83.9% and 53.1%). Younger patients had a lower 10-year survival. In revision RSAs, male patients had a significantly lower survival than females (72.3% vs. 84.5% at 10 years, p = 0.020). Discussion. Primary RSA for cuff-deficient shoulders or POA leads to a high 10-year survival, but revision RSA or primary RSA for FS and tumors are at high-risk for revision. Surgeons should be aware of high rates of complications and lower survival rates of RSA in younger patients, in males, and in RSAs for revision surgery.

Rotator cuff tears

Rotator cuff tears are most commonly the result of age-related degenerative pathology, although they can result from trauma at any age. Patients with rotator cuff tears (RCT) often present with pain, loss of strength and decreased range of motion, which significantly affects their function and quality of life. Some uncertainty persists about optimal treatment strategies and the timing of repairs for some RCTs. The incidence of rotator cuff repairs has rapidly increased in recent years, and studies show that the vast majority of patients go on to experience significant improvements in pain and function, although re-tear is a recognized complication. Novel strategies using grafts to augment repairs are being employed in the hope of reducing these re-tear rates. Augments are expensive and currently not fully supported by high-quality evidence demonstrating their efficacy. The management of larger, potentially irreparable cuff tears is challenging. It remains unclear whether surgery offers effective long-term results for most patients with large and massive cuff tears, as rotator cuff repairs for this cohort are associated with high failure rates.

The role of biodegradable spacer implantation under local anesthesia for patients with massive rotator cuff tears and significant medical comorbidities

Massive rotator cuff tears are common, and the incidence increases with age. They are a challenging problem to deal with as many are irreparable. While there are a host of surgical options available, these can be prolonged procedures requiring general anesthesia and thus not suitable for elderly patients or those with significant medical comorbidities. In this study, we evaluate the role of a biodegradable balloon inserted under local anesthetic for a series of patients with massive cuff tears and significant medical comorbidities. A prospective pilot study was performed on a series of patients between June 2018 and April 2019. Demographic data, as well as preoperative and postoperative clinical data including Subjective Shoulder Value and Oxford Shoulder Scores, were obtained. Four patients with magnetic resonance imaging-proven massive rotator cuff tears involving the supraspinatus were treated with an InSpace balloon under local anesthesia. All were of American Society of Anesthesiologists grade 4 and had exhausted nonoperative treatment. The mean Oxford Shoulder Score improved from a preoperative baseline of 17.25 (range 6-25) to a peak of 25.75 (range 15-34) at the 6-week postoperative mark before declining to 13.67 (range 6-23) at the final follow-up of 6 months. Subjective Shoulder Values also improved initially from a mean of 31.25 (range of 20-40) to a peak of 58.75 (range of 50-70) before reducing to 36.67 (range of 30-50) at the final follow-up of 6 months. We have described the safety and early benefit from the use of a biodegradable balloon spacer inserted under local anesthetic as a management option for patients with massive rotator cuff tears, who may be unfit for other extensive reconstruction options, particularly for short-term pain relief as significant long-term gains were not demonstrated.

AAOS Appropriate Use Criteria: Management of Rotator Cuff Pathology.

AAOS Appropriate Use Criteria: Management of Rotator Cuff Pathology.

Proximal humeral bone defect in reverse shoulder arthroplasty combined with latissimus-dorsi transfer is not related with a poor outcome

BackgroundReverse total shoulder arthroplasty (RSA) associated with modified L’Episcopo (isolated LD) or L’Episcopo (combined TM and LD) procedures had been confirmed to effectively overcome the expected external rotation deficit in patient with postero-superior massive cuff tear and teres minor deficiency. The objective of this study was to evaluate the radiological bony lesions of the lateral proximal humerus following RSA combined with tendon transfer, and to determine whether these bony lesions affect the clinical outcome. Material and methodsA retrospective review of 24 RSAs (mean age 68.71 years, range 52–83) associated with modified L’Episcopo procedure (9) and L’Episcopo procedure (15) was performed. X-rays were assessed for lateral cortex lesions and were categorized into either intact, irregular or complete lytic appearances. In addition, signs of stem loosening were assessed. Clinical outcome measures included range of motion, SSV, VAS, and Constant-Murley scores. ResultsWith a mean follow-up of 44.71 months (12–97; SD 27.42), eight (33.3%) patients demonstrated intact lateral cortex, eight (33.3%) irregular and eight (33.3%) lytic lesions. 40% of cemented stems demonstrated a deformed cortex compared to 74% of cementless stems. Radiolucent lines were detected in one cemented stem (p=0.046). GT resorption (p=0.147), condensations lines (p=0.449) and spot weld (p=0.342), appeared exclusively in non-cemented stem. Postoperatively all patients (24) demonstrated significant improvements in all clinical and functional parameters. A comparison between patient with (Group 2, 16 patients) and without bony lesions (Group 1, 8 patients) revealed no significant differences in functional scores and range of motion: Constant (p=0,61), VAS (p=0,61), SSV (p=0,66) and external rotation (p=0,34). ConclusionAt short-term follow-up, RSA combined with L’Episcopo or modified l’Episcopo procedure resulted in high incidence (67%) of lateral proximal humerus lesions. Radiolucent lines were noted in cemented stems whereas, signs of stress shielding and GT resorption appeared in non-cemented stems. Yet, no case of humeral loosening was detected and these lesions did not seem to affect the clinical outcome. The use of cemented straight standard-length humeral stems should be positively considered in RSA associated with LD\\TM tendon transfer. Level of evidenceIV; retrospective study.