The 24th Annual Meeting of the British Mass Spectrometry Society was held at the University of Reading and attracted over three hundred delegates from all fields of mass spectrometry and related disciplines. The vibrant programme consisted of eight oral sessions, wide- ranging poster sessions and workshops; the final day of the meeting focused on Biomacromolecules, encompassing non-covalent interactions, oligosaccharides, oligonucleotides and proteomics. The previous days' topics covered Instrumental Developments, Separations, Fundamentals, Combinatorial Chemistry, Synthetic Polymers, Environmental and Inorganic mass spectrometry. The meeting was opened by Professor John Monaghan (Chair) and followed by an address from Professor Keith Jennings who gave a brief eulogy for the late Professor Allan Maccoll. Keith gave an overview of the contributions Allan made to mass spectrometry, in particular noting that he was one of the Founders of our Society. Professor Nico Nibbering then delivered the Maccoll Lecture entitled “Recent Chemical Research with the Use of Mass Spectrometry” in which he stressed the importance, to those of the community involved in the study of large biomolecules, of having a good understanding of the fundamentals of the subject. Professor Graham Cooks had the unenviable task of following this splendid lecture but in his usual enthusiastic style delivered a far reaching talk illustrating the potential of ion trap technology. Opening the Environmental session Dr Susan Richardson (U.S. EPA) showed how mass spectrometry played a key role in maintaining the quality of drinking water when so many alternative water disinfectant systems are being introduced that can give rise to Disinfection By-Products. The longest question and answer session of the meeting followed and the delegates were left with no illusions about the need for monitoring and treatment of their water supplies. Two of the keynote/plenary presentations were given by non-mass spectrometrists, Professor Peter Myers and Dr John Reader. Peter opened the Separations session with an in depth and revealing talk on different packing materials and HPLC columns while John covered the need for mass spectrometry from the viewpoint of the combinatorial chemist. The Michael Barber Award for best presentation by young scientists (under 27 years) went to Jennie Lill of Nottingham Trent University for her poster entitled “Metal complexation studies of MHC associated peptides by electrospray mass spectrometry”. From a personal viewpoint one of the most informative and useful presentations was given by Professor Jim Scrivens where he presented a detailed description of synthetic polymer analysis. The workshop sessions were also well attended, covering MS–MS, MALDI and in the New Users workshop Dr Bob Boyd discussed the art of paper writing. The social programme was well attended and included a Firework display to mark our final meeting of the Millennium. Most delegates gave favourable feedback on the content of the meeting and especially liked the expanded and dedicated Manufacturers' Exhibition. We look forward to out 25th Annual Three Day Meeting on 8–12 September 2001 at the University of Southampton with renewed vigour for the future of our Society and its members. The delegates were invited to submit full papers of their presentations and the following are representative of the work presented at the Reading Meeting G. J. Langley University of Southampton, UK January 2000