Mass Loss Research Articles

Optimization of 3D-Printed Solar Evaporators for Enhanced Interfacial Solar Steam Generation and Beyond: Investigating Surface Modifications and Nanocomposite Coatings

The present work investigates the influence of variations in top evaporative surface angle of the 3D-printed solar evaporators in interfacial solar steam generation (ISSG). In this regard, different convex surface modifications such as 0˚, 15˚, 30˚ and 45˚ inclination are fabricated and covered with carbon cloth (CX-0, CX-15, CX-30 and CX-45). Among all, CX-45 evaporator exhibits better ISSG performance and hence, CX-45 evaporator is alone coated with as-synthesized tantalum oxide/potassium tantalate nanocomposite (CX-45/NC) and used to study the enhancement in ISSG. At 1 kW/m2 solar illumination, mass loss (ML), evaporation flux (EF) and efficiency (EY) are measured and found to be 2.5 g, 4.366 kg/m2h and 104.95% respectively for 60 min duration. Furthermore, the outdoor performance (∼656.791 W/m2 for 8 h) of the above evaporator exhibits better ML, EF and EY of about7.5 g, 1.637 kg/m2h and 59.99% respectively. We propose that: (i) increasing the top evaporative surface angle of the 3D evaporator enhances the surface area, facilitating the accumulation of a greater amount of water molecules (ii) the low thermal conductivity of the 3D-printed material prevents excessive heat flow to the bulk water (iii) the presence of water-absorbing groups within the carbon cloth accelerates the rate of water absorption (iv) applying a nanocomposite coating onto the carbon cloth surface enhances its ability to trap light energy effectively (v) enhanced surface roughness of the 3D-printed evaporator minimizes heat losses through mechanisms such as scattering and reflection. Moreover, the developed 3D-printed evaporator gives a sustainable solution for the purification of dye molecules and oil-water separation, as evident from this study.

Eco-Innovation in Energy: Solid Degradation Kinetics of Rejected Red Macroalgae (Kappaphycopsis cottonii) for Bio-Oil and Biochar Production

In the pursuit of renewable energy sources, biomass conversion into biofuels has garnered attention as a sustainable alternative to fossil fuels. This research focuses on the pyrolytic conversion of red macroalgae, specifically rejected Kappaphycus cottonii, an underutilized biomass in Indonesia, into valuable bio-energy carriers, while analyzing the solid degradation kinetics involved. The dried K. cottonii underwent slow pyrolysis at varying temperatures (400‒600 °C) and time intervals (10‒50 min). The impact of these variables on the yield of bio-oil and biochar, alongside the thermogravimetric profiles indicating mass loss, was thoroughly assessed. The study also explores the chemical kinetics of the decomposition process, utilizing the first-order reaction model to analyze the solid biomass conversion rate, activation energy, and frequency factor. Key findings demonstrate that the optimal pyrolysis temperature for maximizing bio-oil yield was precisely 500 °C, beyond which thermal cracking led to yield reductions. Reaction times also greatly affect yield, highlighting the importance of optimized pyrolysis conditions. The determined activation energy and frequency factor, based on the Arrhenius equation, highlighted K. cottonii's lower decomposition energy barrier relative to terrestrial biomass. This distinction is largely ascribed to its unique chemical makeup, notably a lower lignin content, positioning K. cottonii as an advantageous feedstock for biofuel production through pyrolysis.

Impact of acerola pulp on physical and chemical properties of lactose-free sweet bread during storage

The aim of this work was to evaluate the effect of the total replacement of water with acerola pulp on the physical and chemical properties of sweet bread without lactose over five days of storage. Analyses of mass loss, soluble solids, titratable acidity, pH, color, hardness, vitamin C, total phenolics and antioxidant activity were performed daily, for a period of five days, whereas proximate composition was determined just at the same day of baking. The proximate composition was not affected by the replacement of water for acerola pulp. The values of soluble solids and titratable acidity were higher in enriched bread, while pH exhibited the opposite behavior. Enriched bread is softer and more yellowish than control bread, became harder, orange and darker over storage. The levels of vitamin C and total phenolics, as well as the antioxidant activity of the enriched bread was higher than control bread (vitamin C increased from 0 to 33.67 mg/100 g, the total phenolics increased more than fourfold and the antioxidant activity tripled). However, these values gradually decreased over time. The enrichment of free-lactose sweet bread with acerola pulp was successful, providing an alternative for those who aspire to having a healthier diet/ life and for specific diets for those who have difficulty digesting lactose.

Effect of immersion time on bacterial community structure and sulfur metabolism in biofilm on concrete surface in sewer environment

This study focuses on an overlooked but critical issue: the composition and functional expression of microbial communities on the concrete surface in different areas of sewer pipes. Three immersion conditions were applied to simulate the duration of concrete in different areas ofsewers exposed to sewage, including short-term (L1), long-term (L2) and permanent immersion (L3). The properties of concrete under different immersion conditions and the bacterial diversity and functional capabilities in biofilms on the concrete surface were analyzed. Results showed that the L1 group was dominated by Halothiobacillus, whereas Desulfomicrobium was prominent in the L3 group. Significant differences in the predominant functional microbial communities and metabolic functional genes further confirmed the strong impact of immersion time on the pathways of microbial sulfur metabolism and concrete performance in sewer environment. Compared with the L2 and L3 groups, the decreased sewage immersion time resulted in an increase in the abundance and metabolic activity of sulfur-oxidizing bacteria in the L1 group. Hence, greater mass loss and gypsum production of concrete was found in the L1 group. The structural and functional differentiation of bacterial communities on the concrete surface observed in this study contributes to a better understanding of the uneven corrosion in real sewer pipes.

Đánh giá khả năng ức chế ăn mòn đồng M-1 và nhôm AK-7 của benzotriazol trong dung dịch axit xitric 5%

This paper presents the research results on the corrosion inhibition effect of benzotriazole on copper M-1 and aluminum AK-7 in 5% citric acid solution. Electrochemical test resultsshow that benzotriazole as a good corrosion inhibitors for copper M-1 and aluminum AK-7. The optimal protective concentration of benzotriazole in this condition is 0.5%, at which the protective effect for copper M-1 and aluminum AK-7 is 75.43% and 69.56% respectively. After 2 hours of corrosion test in glassware at 88±2°C by mass loss method with a concentration of 0.5% benzotriazole, the protective effect for copper M-1 and aluminum AK-7 reaches 69.1% and 65.4% respectively.

Microstructure Evolution and Molten Salt Corrosion Resistance Dependent on Pre-Oxidation Treatment of NiAl Coatings

The chloride-infused molten salt shows the most potential as the medium for the upcoming generation of concentrated solar power system. However, the molten salt put for ward higher corrosion resistance demand on the critical components of concentrated solar power system. The application of NiAl coating proves to be a highly efficient method for preventing corrosion. In this paper, the microstructure, adhesion, and corrosion resistance of NiAl coatings on 310S stainless steel with/without pre-oxidation treatment were studied. The coating predominantly consisted of β-NiAl phase nanocrystals with an Al content of 41.0 at.%. Continuous α-Al2O3 oxide film was formed and no obvious cracks were observed after pre-oxidation. The adhesion strength of NiAl coating was increased by about 70% to 40.0 N through pre-oxidation. Importantly, the corrosion results of NiAl coatings by pre-oxidation treatment in the mixed salt of NaCl/MgCl2/KCl at 1073.15 K for 10 h showed no obvious diffusion of molten salt elements into the coatings. Compared to 310S stainless steel, the pre-oxidized coating sample exhibited a significant reduction of 50.2% in corrosion mass loss. The pre-oxidation of the NiAl coating creates an Al2O3 oxidation layer that effectively blocks corrosion, offering a new method for protecting stainless steels in concentrated solar power system plants.

Prevalence estimation of sarcopenia using bioelectrical impedance analysis in elderly people in Lahore

Sarcopenia is the loss of muscle mass and strength, or both, and physiological functions through aging. Early detection of muscle weakness results in better care and interventions regarding dietary habits and protein intake in older adults. The objective of this study was to investigate the prevalence of sarcopenia in a Pakistani population and to correlate dietary habits and lifestyle with the prevalence of sarcopenia. A sample size of 150 individuals, both male and female, of age sixty and above was used. Cardiovascular disease and renal failure patients were excluded. The research field was the community of Lahore. Muscle power was calculated using a handgrip strength dynamometer, and gait speed was calculated using a pedometer. After screening, muscle mass was calculated using bioelectrical impedance analysis, from which sarcopenia was diagnosed. In the age group of 60–65 years, 123 individuals (82%) had low muscle strength and 93 (83%) had low muscle mass. In the age group of 66–70 years, 15 individuals (83.3%) had low muscle strength. In the age group of 71–75 years, 9 individuals (90%) had low muscle strength. The percentage of low muscle strength in the age group of 76+ years was 100%. The percentage of severe sarcopenia was 6%, and moderate sarcopenia was approximately 10% for individuals 60 years of age and older. The prevalence rates of sarcopenia were 21.53% in males and 11.76% in females. Sarcopenia is an emerging health issue in older adults, and early detection and lifestyle modification will lead to a better health outcome and correlate dietary habits and lifestyle with the prevalence of sarcopenia.

Nutritional Challenges and Treatment After Bariatric Surgery.

Bariatric surgery is an important weight loss tool in individuals with severe obesity. It is currently the most effective long-term weight loss treatment that lowers obesity-related comorbidities. It also has significant physiological and nutritional consequences that can result in gastrointestinal complications and micronutrient deficiencies. After gastric bypass, common clinical events that negatively affect nutritional status include malabsorption, dumping syndrome, kidney stones, altered intestinal bile acid availability, bowel obstruction, ulcer, gastroesophageal reflux, and bacterial overgrowth. Risk factors for poor nutritional status and excessive loss of lean body mass and bone include reduced dietary quality and inadequate intake, altered nutrient absorption, and poor patient compliance with nutrient supplementation. There are unique concerns in adolescents, older individuals, and individuals who become pregnant postoperatively. With careful management, health-care professionals can assist with long-term weight loss success and minimize the risk of acute and long-term nutrition complications after bariatric surgery.

Widespread seawater intrusions beneath the grounded ice of Thwaites Glacier, West Antarctica

Warm water from the Southern Ocean has a dominant impact on the evolution of Antarctic glaciers and in turn on their contribution to sea level rise. Using a continuous time series of daily-repeat satellite synthetic-aperture radar interferometry data from the ICEYE constellation collected in March-June 2023, we document an ice grounding zone, or region of tidally controlled migration of the transition boundary between grounded ice and ice afloat in the ocean, at the main trunk of Thwaites Glacier, West Antarctica, a strong contributor to sea level rise with an ice volume equivalent to a 0.6-m global sea level rise. The ice grounding zone is 6 km wide in the central part of Thwaites with shallow bed slopes, and 2 km wide along its flanks with steep basal slopes. We additionally detect irregular seawater intrusions, 5 to 10 cm in thickness, extending another 6 km upstream, at high tide, in a bed depression located beyond a bedrock ridge that impedes the glacier retreat. Seawater intrusions align well with regions predicted by the GlaDS subglacial water model to host a high-pressure distributed subglacial hydrology system in between lower-pressure subglacial channels. Pressurized seawater intrusions will induce vigorous melt of grounded ice over kilometers, making the glacier more vulnerable to ocean warming, and increasing the projections of ice mass loss. Kilometer-wide, widespread seawater intrusion beneath grounded ice may be the missing link between the rapid, past, and present changes in ice sheet mass and the slower changes replicated by ice sheet models.

Osteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing.

Cortical bone loss is intricately associated with ageing and coincides with iron accumulation. The precise role of ferroptosis, characterized by iron overload and lipid peroxidation, in senescent osteocytes remains elusive. We found that ferroptosis was a crucial mode of osteocyte death in cortical bone during ageing. Using a single-cell transcriptome analysis, we identified activating transcription factor 3 (ATF3) as a critical driver of osteocyte ferroptosis. Elevated ATF3 expression in senescent osteocytes promotes iron uptake by upregulating transferrin receptor 1 while simultaneously inhibiting solute carrier family 7-member 11-mediated cystine import. This process leads to an iron overload and lipid peroxidation, culminating in ferroptosis. Importantly, ATF3 inhibition in aged mice effectively alleviated ferroptosis in the cortical bone and mitigated cortical bone mass loss. Taken together, our findings establish a pivotal role of ferroptosis in cortical bone loss in older adults, providing promising prevention and treatment strategies for osteoporosis and fractures.

Heterogeneous impacts of ocean thermal forcing on ice discharge from Greenland's peripheral tidewater glaciers over 2000–2021

The Greenland Ice Sheet is losing mass at increasing rates. Substantial amounts of this mass loss occur by ice discharge which is influenced by ocean thermal forcing. The ice sheet is surrounded by thousands of peripheral, dynamically decoupled glaciers. The mass loss from these glaciers is disproportionately high considering their negligible share in Greenland’ overall ice mass. We study the relevance of ocean thermal forcing for ice discharge evolution in the context of this contrasting behaviour. Our estimate of ice discharge from the peripheral tidewater glaciers yields a rather stable Greenland-wide mean of 5.40 ± 3.54 Gt a−1 over 2000–2021. The evolutions of ice discharge and ocean thermal forcing are heterogeneous around Greenland. We observe a significant sector-wide increase of ice discharge in the East and a significant sector-wide decrease in the Northeast. Ocean thermal forcing shows significant increases along the northern/eastern coast, while otherwise unchanged conditions or decreases prevail. For East Greenland, this implies a clear influence of ocean thermal forcing on ice discharge. Similarly, we find clear influences at peripheral tidewater glaciers with thick termini that are similar to ice sheet outlet glaciers. At the peripheral glaciers in Northeast Greenland ice discharge evolution opposes ocean thermal forcing for unknown reasons.

Mass Loss from the Atmosphere of the Planet TOI-1442 c

Mass Loss from the Atmosphere of the Planet TOI-1442 c

Activity of the Star TOI-784 and Loss of Atmospheric Mass by Its Planet

Activity of the Star TOI-784 and Loss of Atmospheric Mass by Its Planet

Uncovering sarcopenia and frailty in older adults by using muscle ultrasound—A narrative review

Muscle ultrasound is a valuable non-invasive and cost-effective method in assessing muscle mass and structure, both of which are significant indicators for the development of sarcopenia and frailty in elderly individuals. Sarcopenia refers to the loss of muscle mass and strength that occurs with age, whereas frailty is a complex geriatric syndrome characterized by reduced physical function and an increased susceptibility to negative health outcomes. Both conditions are prevalent in older adults and are associated with higher risks of falls, disability, and mortality. By measuring muscle size and structure and several other ultrasound parameters, including muscle thickness, cross-sectional area, echogenicity (brightness in the ultrasound image), pennation angle, and fascicle length ultrasound can assist in identifying sarcopenia and frailty in older adults. In addition, ultrasound can be used to evaluate muscle function such as muscle contraction and stiffness, which may also be affected in sarcopenia and frailty. Therefore, muscle ultrasound could lead to better identification and tracking of sarcopenia and frailty. Such advancements could result in the implementation of earlier interventions to prevent or treat these conditions, resulting in an overall improvement in the health and quality of life of the elderly population. This narrative review describes the benefits and challenges when using ultra-sound for the evaluation of frailty and sarcopenia.

Effect of Heat Treatment on the Supramolecular Structure of Copolymers Based on Poly(propylene glycol fumarate phthalate) with Acrylic Acid

Previous studies investigating the thermal decomposition of p-PGFPh:AA copolymers in an inert atmosphere have provided only a general understanding of the changes that occur during thermolysis. Comprehensive studies are required to gain a better understanding of these processes [1]. The most comprehensive information on the influence of various factors on both the kinetics and the supramolecular structure of the resulting products can be obtained by combining the method of thermal analysis with IR, mass spectrometry, and scanning electron microscopy. The compounds studied have two different compositions, namely p‑PGFPh:AA 6.77:93.23 mol % and p-PGFPh:AA 86.67:13.33 mol %. These compounds were then subjected to a thermolysis process, which resulted in the emission of gases and a decrease in sample weight. The degradation process can be divided into three stages: 1) Depolymerization of the main chain; 2) Depolymerization of the side chain; 3) Final decomposition. These processes occur sequentially at different temperature ranges. According to TG- and DTG studies, complete decomposition of p-PGFPh:AA copolymers occurred at Tterm = 340–350 °C. In this temperature range, a slight loss of sample mass (less than 10 wt %) was observed along with a slight gas evolution. The main gaseous products from the transformation of the studied samples were CO and CO2. This was supported by IR-CO (2000–2200 cm−1) and CO2 (2310–2370 cm−1) as well as mass spectrometric observations. The final products resulting from the thermolysis of p-PGFPh:AA copolymers were examined under an electron microscope. The results showed a similar morphological pattern of mesostructures with sizes ranging from 0.3–1.5 μm, which were observed depending on the porous structure of the initial polymer material. Based on the experimental data, it can be concluded that the p-PGFPh:AA copolymers (in proportions of 6.77:93.23 mol % and 86.67:13.33 mol %) have a relatively high degree of resistance to heating and do not undergo any changes in chemical composition, particle size and shape. In conclusion, the results clearly indicate that the selection of conditions for pyrolysis plays a crucial role in increasing the thermal stability of polymeric materials. This method allows for purposeful changes in the structure and properties of polymers.

Feasibility study on thin‐film PV laminates for road integration

AbstractIntegration of photovoltaics (PV) into the built environment (BIPV) and infrastructure (IIPV) is required to increase the installed capacity of PV worldwide, while still leaving sufficient area for other land uses. Although BIPV applications have proven to play a significant role in the energy transition, road integrated IIPV concepts are less developed and bring challenges in mechanical and electrical stability and safety that still need to be addressed. In this work, the feasibility of integrating thin‐film CIGS (Copper Indium Gallium Selenide) modules into road tiles is investigated. PV road stacks were produced by gluing CIGS laminates onto concrete tiles and covering them with epoxy and glass granulates to form impact‐ and anti‐skid layers. IV (current–voltage) characteristics show that, respectively, a thin and thick epoxy layer results in 2% and 6.6% relative loss in power conversion efficiency. Although a thin protective layer would be beneficial to the power conversion efficiency of road modules, raveling tests show increased risk for electrical failure when a thin top layer is used. Pull‐off tests showed that the weakest adhesive strength (0.8 N/mm2) is between the thin‐film laminate and concrete, offering sufficient adhesive strength to at least withstand light traffic loading. Raveling and wheel tracking tests show no mass loss and only minor deformation of the stack, respectively, indicating no real risk of raveling or rutting. Thermal cycling and damp heat exposure of the PV road tiles show that yellowing of the top layers can significantly reduce performance over longer periods of outdoor operation. Damp heat exposure after mechanical loading shows no indication of moisture ingress on any of the tested configurations, suggesting the proposed CIGS laminate stack is able to withstand light traffic loading. From the measurement results, it can be concluded that thin‐film CIGS modules are mechanically and electrically suitable for road integration. Power conversion efficiencies over 12% can be attained with this technology, indicating its potential for renewable energy generation in road infrastructure. Performance stability can especially benefit from alternative top layer materials that maintain high transparency over long lifetimes. Additionally, pilot tests are required to demonstrate the potential of the technology in a controlled outdoor environment.

On the formation of a 33 solar-mass black hole in a low-metallicity binary

A 33M⊙ black hole (BH) was recently discovered in an 11.6-year binary only 590 pc from the Sun. The system, Gaia BH3, contains a 0.8M⊙ low-metallicity giant () that is a member of the ED-2 stellar stream. This paper investigates whether the system could have formed via isolated binary evolution. I construct evolutionary models for metal-poor massive stars with initial masses ranging from 35−55M⊙, which reach maximum radii of 1150−1800R⊙ as red supergiants. I then explore what combinations of initial orbit, mass loss, and natal kick can produce the period and eccentricity of Gaia BH3. Initial orbits wide enough to accommodate the BH progenitor as a red supergiant can match the observed period and eccentricity, but only if the BH formed with a significant natal kick (). These models are disfavored because such a kick would have ejected the binary from the ED-2 progenitor cluster. I conclude that Gaia BH3 likely formed through dynamical interactions, unless the BH progenitor did not expand to red supergiant dimensions. Only about 1 in 10,000 stars in the solar neighborhood have metallicities as low as Gaia BH3. This suggests that BH companions are dramatically over-represented at low-metallicity, though caveats related to small number statistics apply. The fact that the luminous star in Gaia BH3 has been a giant – greatly boosting its detectability – only for $$1% of the time since the system’s formation implies that additional massive BHs remain to be discovered with only moderately fainter companions. Both isolated and dynamically-formed BH binaries with orbits similar to Gaia BH3 are likely to be discovered in Gaia DR4.

Advancing towards greener healthcare: Innovative solutions through single-use mask waste to refuse-derived fuel utilization

The healthcare sector faces increasing challenges in managing the environmental impact of single-use masks and medical waste, prompting the exploration of innovative solutions for greener healthcare. This study investigates converting single-use mask waste into Refuse Derived Fuel (RDF) as a sustainable waste management approach. A quantitative analysis assessed the average waste generation of single-use masks in a healthcare facility over three months. The potential RDF production was estimated by calculating single-use masks' weight and calorific value. Additionally, Thermogravimetric Analysis was employed to evaluate the thermal behavior of RDF and its suitability as an alternative fuel source. The findings indicate an average monthly waste generation of 41,555 masks weighing 111.2 kg. RDF production from single-use mask waste yields a daily output of 3.706 kg, providing a promising solution to reduce medical waste. TGA analysis reveals a multi-step degradation process for RDF, with a significant mass loss between 300 and 500 °C, rendering it a viable renewable energy source. Converting single-use mask waste into RDF presents an opportunity for healthcare institutions to contribute to net-zero emission goals, reducing reliance on fossil fuels and embracing sustainable waste management practices.

Carbon fiber‐reinforced thermoplastic synthesized by the hypercrosslinking reaction of polyether ether ketone

AbstractRecently, thermoplastic resins were used as matrix to synthesize carbon fiber‐reinforced thermoplastic (CFRTP) for recycling it easily. In this study, a CFRTP with excellent mechanical properties and heat resistance was synthesized using a polyether ether ketone (PEEK) as a matrix resin. The PEEK resin was modified to form cross‐linked structures through Friedel–Crafts reaction alkylation. The synthesis temperature of CFRTP was optimized considering the mechanical properties of PEEK, and its heat resistance was enhanced because of the cross‐linked structures. Further, the cross‐linked PEEK resin was partially used as a matrix resin, and the mechanical properties of the CFRTP were enhanced. We plan to develop a method for recycling CFRTP using PEEK and crosslinked PEEK for synthesizing C/C composites by focusing on the high heat resistance of the crosslinked PEEK containing a large amount of carbon and reducing mass loss after heat treatment.Highlights CC bonds were introduced into the polyether ether ketone (PEEK) resin by Friedel–Crafts reaction alkylation. Thermal properties of PEEK were enhanced by hypercrosslinking reaction. Optimization of synthesized temperature was investigated to fabricate carbon fiber‐reinforced thermoplastic (CFRTP). Mechanical properties were enhanced CFRTP modified with hypercrosslinking reaction.

Myostatin gene invalidation does not prevent skeletal muscle mass loss during experimental sepsis in mice.

Loss of muscle mass and function induced by sepsis contributes to physical inactivity and disability in intensive care unit patients. Limiting skeletal muscle deconditioning may thus be helpful in reducing the long-term effect of muscle wasting in patients. We tested the hypothesis that invalidation of the myostatin gene, which encodes a powerful negative regulator of skeletal muscle mass, could prevent or attenuate skeletal muscle wasting and improve survival of septic mice. Sepsis was induced by caecal ligature and puncture (CLP) in 13-week-old C57BL/6J wild-type and myostatin knock-out male mice. Survival rates were similar in wild-type and myostatin knock-out mice seven days after CLP. Loss in muscle mass was also similar in wild-type and myostatin knock-out mice 4 and 7 days after CLP. The loss in muscle mass was molecularly supported by an increase in the transcript level of E3-ubiquitin ligases and autophagy-lysosome markers. This transcriptional response was blunted in myostatin knock-out mice. No change was observed in the protein level of markers of the anabolic insulin/IGF1-Akt-mTOR pathway. Muscle strength was similarly decreased in wild-type and myostatin knock-out mice 4 and 7 days after CLP. This was associated with a modified expression of genes involved in ion homeostasis and excitation-contraction coupling, suggesting that a long-term functional recovery following experimental sepsis may be impaired by a dysregulated expression of molecular determinants of ion homeostasis and excitation-contraction coupling. In conclusion, myostatin gene invalidation does not provide any benefit in preventing skeletal muscle mass loss and strength in response to experimental sepsis. KEY POINTS: Survival rates are similar in wild-type and myostatin knock-out mice seven days after the induction of sepsis. Loss in muscle mass and muscle strength are similar in wild-type and myostatin knock-out mice 4 and 7 days after the induction of an experimental sepsis. Despite evidence of a transcriptional regulation, the protein level of markers of the anabolic insulin/IGF1-Akt-mTOR pathway remained unchanged. RT-qPCR analysis of autophagy-lysosome pathway markers indicates that activity of the pathway may be altered by experimental sepsis in wild-type and myostatin knock-out mice. Experimental sepsis induces greater variations in the mRNA levels of wild-type mice than those of myostatin knock-out mice, without providing any significant catabolic resistance or functional benefits.