Massive Formation Research Articles

The impact of stellar bars on star-formation quenching: Insights from a spatially resolved analysis in the local Universe

Stellar bars are common morphological structures in the local Universe; according to optical and NIR surveys, they are present in about two-thirds of disc galaxies. These elongated structures are also believed to play a crucial role in secular evolutionary processes, because they are able to efficiently redistribute gas, stars, and angular momentum within their hosts, although it remains unclear as to whether they enhance or suppress star formation. A useful tool to investigate this ambiguity is the main sequence (MS) relation, which tightly links stellar mass ($M_ star $) and star formation rate (SFR). The main goal of this work is to explore star-formation processes in barred galaxies in order to assess the relevance of bars in star-formation quenching and whether or not they affect the typical log-linear trend of the resolved MS. To this purpose, we carried out a spatially resolved analysis on subkiloparsec (subkpc) scales for a sample of six nearby barred galaxies. We collected multi-wavelength photometric data from far-ultraviolet (FUV) to far-infrared (FIR) from the DustPedia database and applied a panchromatic spectral energy distribution (SED) fitting procedure on square apertures of fixed angular size ( arcsec times arcsec ) using the magphys code. For each galaxy, we obtain the distributions of stellar mass and SFR surface density and relate them in the $ star SFR $ plane, deriving the spatially resolved MS relation. Although significant galaxy-to-galaxy variations are in place, we infer the presence of a common anti-correlation track in correspondence with the bar-hosting region, which shows systematically lower SFRs. This central quiescent signature can be interpreted as the result of a bar-driven depletion of gas reservoirs and a consequent halting of star formation. Our findings appear to support an inside-out quenching scenario.

Symbolic regression based prediction of anisotropic closure in deep tunnels

This work investigates the applicability of Genetic Programming with Symbolic Regression to analyse the closure evolution of tunnels during and after excavation. Special attention is given to anisotropic closure evolution, which depends on the anisotropy of the initial stress state and the intrinsic anisotropy of the rock mass formation. A methodology is proposed that takes into account the information recorded during excavation to train the algorithm and find a free-form simple mathematical expression that captures the closure evolution over time. The proposed methodology is applied to two case studies of deep tunnels with high anisotropic convergence evolution. The results obtained show that this approach performs well with the small dataset used in this work. The proposed approach is an interesting tool to improve the understanding and prediction of the ground response.

The harmfulness of weeds in the herbage of perennial grasses in the north-west of the Russian Federation

Relevance. In the structure of the acreage of the Northwestern region of the Russian Federation, a large proportion is occupied by perennial grasses, the herbage of which can potentially have severe weeds, and the harmfulness of weeds is high. Despite the current situation, the influence of weeds on the formation of an aboveground mass of grasses remains poorly understood.Methods. The purpose of the study is to assess the harmfulness of weed vegetation in the herbage of perennial grasses of the 1st and 2nd years of use in the north-west of the Russian Federation. The research was carried out in 2010–2018 in the fields of grain-grass-row crop rotation of the Menkovsky branch of the Agrophysical Research Institute located in the Leningrad region, in the structure of long-term experience with the application of mineral fertilizers and plant protection products.Results. Studies have shown that weeds cause significantly more harm (6.3 times) to perennial grasses of the 1st year of use than grasses of the 2nd year. Yield losses from the total value of the raw phytomass of weeds amounted to 15.75 c/ha (5.3%) and 2.51 c/ha (1%), including from 1 g/m2 at the time of mowing 0.150 c/ha (0.05%) and 0.07 c/ha (0.03%). The introduction of high doses of mineral fertilizers and the use of herbicides in the integrated crop protection system of grain-grass-row crop rotation led to a decrease in the harmfulness of weeds. In the perennial herbs of the 2nd year of use, the identified effects were significantly more pronounced than in the herbs of the 1st year. Under the influence of mineral fertilizers, the hazard coefficients decreased by 2.6 and 5.7 times, the protective measures systems — by 1.4 and 4.2 times, and the yield losses of green mass — by 2.6 and 10.7 times, 1.9 and 8.9 times, respectively, on grasses of the 1st and 2nd years of use.

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy

BackgroundSpinal muscular atrophy (SMA) is a devastating neuromuscular disease caused by hypomorphic loss of function in the survival motor neuron (SMN) protein. SMA presents across a broad spectrum of disease severity. Unfortunately, genetic models of intermediate SMA have been difficult to generate in vertebrates and are thus unable to address key aspects of disease etiology. To address these issues, we developed a Drosophila model system that recapitulates the full range of SMA severity, allowing studies of pre-onset biology as well as late-stage disease processes.ResultsHere, we carried out transcriptomic and proteomic profiling of mild and intermediate Drosophila models of SMA to elucidate molecules and pathways that contribute to the disease. Using this approach, we elaborated a role for the SMN complex in the regulation of innate immune signaling. We find that mutation or tissue-specific depletion of SMN induces hyperactivation of the immune deficiency (IMD) and Toll pathways, leading to overexpression of antimicrobial peptides (AMPs) and ectopic formation of melanotic masses in the absence of an external challenge. Furthermore, the knockdown of downstream targets of these signaling pathways reduced melanotic mass formation caused by SMN loss. Importantly, we identify SMN as a negative regulator of a ubiquitylation complex that includes Traf6, Bendless, and Diap2 and plays a pivotal role in several signaling networks.ConclusionsIn alignment with recent research on other neurodegenerative diseases, these findings suggest that hyperactivation of innate immunity contributes to SMA pathology. This work not only provides compelling evidence that hyperactive innate immune signaling is a primary effect of SMN depletion, but it also suggests that the SMN complex plays a regulatory role in this process in vivo. In summary, immune dysfunction in SMA is a consequence of reduced SMN levels and is driven by cellular and molecular mechanisms that are conserved between insects and mammals.

Appendectomy Open Versus Laparoscopic in Developing World Scenario

Background: Laparoscopic surgery is an expanding field which is recognized as gold standard for cholecystectomy, it is being increasingly used by many surgical subspecialties with advantage of being minimal invasive and being both diagnostic and therapeutic. Objectives: This study was done to evaluate the feasibility of laparoscopic appendectomy in a developing world scenario.Material and Methods: This observational cross-sectional study was conducted under department of general surgery from September 2019 to August 2021. The patients presenting to the ER department were evaluated based on Alvarado score. Alternate patients underwent laparoscopic appendectomy (LA) and open appendectomy (OA). Based upon clinical and imaging signs of acute appendicitis (i.e. Alvarado score of 7 or more) and consent to be the part of study, were used as inclusion criteria, while pregnancy, patients who could not tolerate increased intra-abdominal pressure/prolonged anesthesia, patients under 10 years of age and patients with evidence of appendicular mass formation were excluded from the study. The standard surgical techniques were performed for both groups and the patients were followed up in immediate post-operative period, at 6 months and one year. Results: The parameters observed were duration of surgery average 25 minutes (range 15-50 mins) for OA and 70 minutes (range 40-90 mins) for LA (P-Value 1.41E-70), return to preoperative activity level was 13 days (range 10-17 days) for OA and 10 days (range 9-14 days) for LA (P-Value 6.69034E-22), and average cost for OA was PKR 35279.00 while for LA was PKR 72168.00 (P-Value 1.24442E-60). Remaining parameters were not significantly different.Conclusion: The evidence available clearly demonstrates that laparoscopic appendectomy is superior to open appendectomy in terms of hospital stay, post-operative pain and return to work, however in a few situations the procedure needs to be converted therefore the surgeon must be conversant with open appendectomy for complicated case. Moreover, cost is a major factor determining the choice of procedure specially in the developing countries. Keywords: Appendectomy, Developing world, Laparoscopic Appendectomy, Open versus Laparoscopic Appendectomy, Pakistan,

Time course of tumorigenesis of a newly developed sporadic hemangioblastoma in an elderly patient: illustrative case.

von Hippel-Lindau disease-associated hemangioblastomas (HBs) account for 20%-30% of all HB cases, with the appearance of new lesions often observed in the natural course of the disease. By comparison, the development of new lesions is rare in patients with sporadic HB. A 65-year-old man underwent clipping for an unruptured aneurysm of the anterior communicating artery. Fourteen years later, follow-up magnetic resonance imaging (MRI) revealed a strongly enhanced mass in the right cerebellar hemisphere, diagnosed as a sporadic HB. A retrospective review of MRI studies obtained over the follow-up period revealed the gradual development of peritumoral edema and vascularization before mass formation. Newly appearing high-intensity T2 lesions in the cerebellum may represent a preliminary stage of tumorigenesis. Careful monitoring of these patients would be indicated, which could provide options for early treatment to improve patient outcomes.

Magmatic evolution of the Kolumbo submarine volcano and its implication to seafloor massive sulfide formation

Seafloor massive sulfides form in various marine hydrothermal settings, particularly within volcanic arcs, where magmatic fluids may contribute to the metal budget of the hydrothermal system. In this study, we focus on the Kolumbo volcano, a submarine volcanic edifice in the central Hellenic Volcanic Arc hosting an active hydrothermal system. Diffuse sulfate-sulfide chimneys form a Zn-Pb massive sulfide mineralization with elevated As, Ag, Au, Hg, Sb, and Tl contents. These elements have similar behavior during magmatic degassing and are common in arc-related hydrothermal systems. Trace-element data of igneous magnetite, combined with whole rock geochemistry and numerical modelling, highlights the behavior of chalcophile and siderophile elements during magmatic differentiation. We report that, despite early magmatic sulfide saturation, chalcophile element contents in the magma do not decrease until water saturation and degassing has occurred. The conservation of chalcophile elements in the magma during magmatic differentiation suggests that most of the magmatic sulfides do not fractionate. By contrast, upon degassing, As, Ag, Au, Cu, Hg, Sb, Sn, Pb, and Zn become depleted in the magma, likely partitioning into the volatile phase, either from the melt or during sulfide oxidation by volatiles. After degassing, the residual chalcophile elements in the melt are incorporated into magnetite. Trace-element data of magnetite enables identifying sulfide saturation during magmatic differentiation and discrimination between pre- and post-degassing magnetite. Our study highlights how magmatic degassing contributes to the metal budget in magmatic-hydrothermal systems that form seafloor massive sulfides and shows that igneous magnetite geochemistry is a powerful tool for tracking metal-mobilizing processes during magmatic differentiation.

Feline Facial Spindle Cell Tumors in 29 Cats: Histomorphological and Immunohistochemical Characterization.

Soft tissue tumors/sarcomas (STSs) in felines, encompassing a variety of mesenchymal tumors with similar histomorphological features, present diagnostic challenges due to their diverse cellular origins and the overlap with other tumor types such as feline sarcoid. This study aimed to delineate the clinical, histomorphological, and immunohistochemical characteristics of 34 feline facial spindle cell tumors affecting 29 cats, including testing for bovine papillomavirus type 14 (BPV14), the virus causing feline sarcoids. Only five out of 12 tumors previously diagnosed as feline sarcoids based on histomorphology were confirmed by PCR for BPV14, underscoring the importance of comprehensive diagnostic approaches to accurately distinguish between STSs and feline sarcoids. This study shows that most facial spindle cell tumors were compatible with peripheral nerve sheath tumors (PNSTs) based on positive immunohistochemical staining for Sox10 and other immunohistochemical markers such as GFAP, NSE, and S100. Some of these tumors displayed as multiple independent masses on the face or as erosive and ulcerative lesions without obvious mass formation, an atypical presentation and an important highlight for general practitioners, dermatologists, and oncologists. This study also describes periadnexal whorling of neoplastic cells as a novel histomorphologic finding in feline facial PNSTs and emphasizes Sox10 as a useful complementary immunohistochemical marker for the diagnosis of facial PNST in cats, providing valuable insights for veterinary pathologists.

409 Evaluation of a Novel Vancomycin-Infused, Biomimetic Bone Graft in a Rat model of Spinal Implant-Associated Infection

INTRODUCTION: Postoperative infection is a complication of spinal fusion surgery resulting in increased patient morbidity. Strategies including intraoperative application of powdered vancomycin have been proposed to reduce the incidence of infection, however such antimicrobial effects are short-lived. METHODS: Instrumentation of the L4-L5 vertebrae was performed mimicking pedicle screw and rod fixation in 30 rats. Titanium inoculated with PBS or 1x105 CFU bioluminescent MRSA and biomimetic bone grafts infused with varying concentrations of vancomycin were inserted before closure. Infection was quantified during the six-week postoperative period using IVIS bioluminescent imaging. Arthrodesis was evaluated using micro-CT. Histological analysis was utilized to evaluate fusion and leukocyte infiltration. RESULTS: Infected animals receiving a bone graft infused with high-dose vancomycin (0.89 mg/g) exhibited significantly lower bioluminescent signal over the six-week postoperative infection period (p = 0.032) than control animals inoculated with MRSA and implanted with bone grafts lacking vancomycin. Both high and low-dose (0.18 mg/g) vancomycin-infused grafts resulted in a statistically significant reduction in average bioluminescence when compared to control animals (p = 0.018 and p = 0.027, respectively), independent of time. MicroCT analysis of animals from each group revealed pseudoarthrosis only in the control group, suggesting a correlation between infection and pseudoarthrosis. Histology revealed the formation of fusion masses in all animals receiving vancomycin infused-bone grafts regardless of MRSA inoculation, with clearance of infection indicated by lack of abscess formation. MRSA-inoculated control animals receiving no vancomycin within the bone graft demonstrated significant abscess formation and lack of fusion mass. CONCLUSIONS: The novel vancomycin-infused, biomimetic bone graft effectively mitigated implant-associated infection while promoting fusion in a rat model of instrumented lumbar fusion.

Comparing the effects of Al-based coagulants in waste activated sludge anaerobic digestion: Methane yield, kinetics and sludge implications

Due to its effectiveness and ease of application, the process of flocculation and coagulation is often used for pollution removal in wastewater treatment. Most of these coagulants precipitate and accumulate in waste activated sludge (WAS), and could negatively affect sludge treatments, as observed for anaerobic digestion. Nowadays, wastewater treatment plants (WWTPs) are widely discussed because of the current paradigm shift from linear to circular economy, and the treatments performed at the facility should be planned to avoid or reduce adverse effects on other processes. The aim of this study was to compare the impact of poly aluminum chloride (PAC) and aluminum sulfate (AS) on WAS anaerobic digestion, by feeding replicate serum reactors with different levels of coagulant (5, 10 and 20 mg Al/g TS). Reactors without the addition of any coagulants represented the control group. Results revealed that Al-based coagulants inhibited methane production, which decreased as the coagulant addition increased. The inhibition was much more severe in AS-conditioned reactors, showing average reductions in methane yield from 14.4 to 31.7%, compared to the control (167.76 ± 1.88 mL CH4/g VS). Analytical analysis, FTIR and SEM investigations revealed that the addition of coagulants affected the initial conditions of the anaerobic reactors, penalizing the solubilization, hydrolysis and acidogenesis phases. Furthermore, the massive formation of H2S in AS-conditioned reactors played a key role in the suppression of methane phase. On the other hand, the use of coagulant can promote the accumulation and recovery of nutrient in WAS, especially in terms of phosphorus. Our findings will expand research knowledge in this field and guide stakeholders in the choice of coagulants at full scale plant. Future research should focus on reducing the effect of coagulants on methane production by modifying or testing new types of flocculants.

A fractional mathematical model approach on glioblastoma growth: tumor visibility timing and patient survival

In this paper, we introduce a mathematical model given by
 \begin{equation}
 { }^c \mathfrak{D}_t^\alpha u = \nabla \cdot \mathrm{D} \nabla u + \rho f(u) \quad \text{in } \Omega,
 \end{equation}
 where $f(u)=\frac{1}{1-u/\mathrm{K}}, \, u/\mathrm{K} \neq 1, \, \mathrm{K} > 0$, to enhance established mathematical methodologies for better understanding glioblastoma dynamics at the macroscopic scale. The tumor growth model exhibits an innovative structure even within the conventional framework, including a proliferation term, $f(u)$, presented in a different form compared to existing macroscopic glioblastoma models. Moreover, it represents a further refined model by incorporating a calibration criterion based on the integration of a fractional derivative, $\alpha$, which differs from the existing models for glioblastoma. Throughout this study, we initially discuss the modeling dynamics of the tumor growth model. Given the frequent recurrence observed in glioblastoma cases, we then track tumor mass formation and provide predictions for tumor visibility timing on medical imaging to elucidate the recurrence periods. Furthermore, we investigate the correlation between tumor growth speed and survival duration to uncover the relationship between these two variables through an experimental approach. To conduct these patient-specific analyses, we employ glioblastoma patient data and present the results via numerical simulations. In conclusion, the findings on tumor visibility timing align with empirical observations, and the investigations into patient survival further corroborate the well-established inter-patient variability for glioblastoma cases.

Primordial intermediate and supermassive black hole formation during the electron–positron annihilation epoch

ABSTRACT Some of the Intermediate Mass Black Hole candidates observed at the centre of galaxies or in globular clusters and some of the Supermassive Black Holes seen at the centre of many galaxies might be of primordial origin. Indeed, Primordial Black Holes (PBHs) of such mass could have formed when the Universe was ∼1–103 s old, due to the collapse of density fluctuations. In particular, when the Universe was ∼1 s in age, Electron–Positron Annihilation (EPA) took place. We explore the formation of intermediate mass and supermassive PBHs, taking into account the effect of the EPA when the fluctuations have a running tilt power-law spectrum: when these cross the 10−0.5–103.0 s Universe horizon they could produce 5 × 103–5 × 108 M⊙ PBHs with a density as high as ∼1010/Gpc3. On average, this implies a population of about one thousand PBHs in the Local Group of Galaxies, with the nearest one at about 250 kpc, just under half the distance to the Andromeda galaxy (M31).

Highly sensitive plasmonic paper substrate fabricated via amphiphilic polymer self-assembly in microdroplet for detection of emerging pharmaceutical pollutants

We report an innovative and facile approach to fabricating an ultrasensitive plasmonic paper substrate for surface-enhanced Raman spectroscopy (SERS). The approach exploits the self-assembling capability of poly(styrene-b-2-vinyl pyridine) block copolymers to form a thin film at the air-liquid interface within the single microdroplet scale for the first time and the subsequent in situ growth of silver nanoparticles (AgNPs). The concentration of the block copolymer was found to play an essential role in stabilizing the droplets during the mass transfer phase and formation of silver nanoparticles, thus influencing the SERS signals. SEM analysis of the morphology of the plasmonic paper substrates revealed the formation of spherical AgNPs evenly distributed across the surface of the formed copolymer film with a size distribution of 47.5 nm. The resultant enhancement factor was calculated to be 1.2 × 107, and the detection limit of rhodamine 6G was as low as 48.9 pM. The nanohybridized plasmonic paper was successfully applied to detect two emerging pollutants—sildenafil and flibanserin—with LODs as low as 1.48 nM and 3.45 nM, respectively. Thus, this study offers new prospects for designing an affordable and readily available, yet highly sensitive, paper-based SERS substrate with the potential for development as a lab-on-a-chip device.

A Measurement of the Assembly of Milky Way Analogs at Redshifts 0.5 < z < 2 with Resolved Stellar Mass and Star Formation Rate Profiles

The resolved mass assembly of Milky Way–mass galaxies has been previously studied in simulations, the local Universe, and at higher redshifts using infrared (IR) light profiles. To better characterize the mass assembly of Milky Way analogs (MWAs), as well as their changes in star formation rate (SFR) and color gradients, we construct resolved stellar mass and SFR maps of MWA progenitors selected with abundance matching techniques up to z ∼2 using deep, multiwavelength imaging data from the Hubble Frontier Fields. Our results using stellar mass profiles agree well with previous studies that utilize IR light profiles, showing that the inner 2 kpc of the galaxies and the regions beyond 2 kpc exhibit similar rates of stellar mass growth. This indicates the progenitors of MWAs from z ∼ 2 to the present do not preferentially grow their bulges or their disks. The evolution of the SFR profiles indicates a greater decrease in SFR density in the inner regions versus the outer regions. Sérsic parameters indicate modest growth in the central regions at lower redshifts, perhaps indicating slight bulge growth. However, the Sérsic index does not rise above n ∼ 2 until z < 0.5, meaning these galaxies are still disk-dominated systems. We find that the half-mass radii of the MWA progenitors increase between 1.5 < z < 2, but remain constant at later epochs (z < 1.5). This implies mild bulge growth since z ∼ 2 in MWA progenitors, in line with previous MWA mass assembly studies.

Analysis of the results of histological examination of unilateral nasal polyps

Unilateral rhinosinusitis (primary or secondary) is the most common process among diseases that cause the formation of polyps or polyp-like masses in one side of the nose. However, histological analysis in these cases often reveals non-inflammatory diseases. A retrospective analysis of the results of histological examina tion of unilateral nasal polyps in 42 patients revealed benign and malignant tumors in 16.7% of cases. These results indicate the need for histological studies in unilateral processes, since this reduces the risk of late malignancy detection.

Catgut embedding in acupoints combined with repetitive transcranial magnetic stimulation for the treatment of postmenopausal osteoporosis: study protocol for a randomized clinical trial.

To date, the clinical modulation for bone metabolism based on the neuro-bone mass regulation theory is still not popular. The stimulation of nerve systems to explore novel treatments for Postmenopausal osteoporosis (PMOP) is urgent and significant. Preliminary research results suggested that changes brain function and structure may play a crucial role in bone metabolism with PMOP. Thus, we set up a clinical trial to investigate the effect of the combination of repetitive transcranial magnetic stimulation (rTMS) and catgut embedding in acupoints (CEA) for PMOP and to elucidate the central mechanism of this neural stimulation in regulating bone metabolism. This trial is a prospective and randomized controlled trial. 96 PMOP participants will be randomized in a 1:1:1 ratio into a CEA group, an rTMS group, or a combined one. Participants will receive CEA, rTMS, or combined therapy for 3 months with 8 weeks of follow-up. The primary outcomes will be the changes in Bone Mineral Density scores, total efficiency of Chinese Medicine Symptoms before and after treatment. Secondary outcomes include the McGill Pain Questionnaire Short-Form, Osteoporosis Symptom Score, Mini-Mental State Examination, and Beck Depression Inventory-II. The leptin, leptin receptor, and norepinephrine levels of peripheral blood must be measured before and after treatment. Adverse events that occur during the trial will be recorded. CEA achieves brain-bone mass regulation through the bottom-up way of peripheral-central while rTMS achieves it through the top-down stimulation of central-peripheral. CEA combined with rTMS can stimulate the peripheral-central at the same time and promote peripheral bone mass formation. The combination of CEA and rTMS may play a coordinating, synergistic, and side-effect-reducing role, which is of great clinical significance in exploring better treatment options for PMOP.Clinical trial registration: https://www.chictr.org.cn/, identifier ChiCTR2300073863.

Genetic diversity and candidate genes for transient waterlogging tolerance in mungbean at the germination and seedling stages.

Mungbean [Vigna radiata var. radiata (L.) Wilczek] production in Asia is detrimentally affected by transient soil waterlogging caused by unseasonal and increasingly frequent extreme precipitation events. While mungbean exhibits sensitivity to waterlogging, there has been insufficient exploration of germplasm for waterlogging tolerance, as well as limited investigation into the genetic basis for tolerance to identify valuable loci. This research investigated the diversity of transient waterlogging tolerance in a mini-core germplasm collection of mungbean and identified candidate genes for adaptive traits of interest using genome-wide association studies (GWAS) at two critical stages of growth: germination and seedling stage (i.e., once the first trifoliate leaf had fully-expanded). In a temperature-controlled glasshouse, 292 genotypes were screened for tolerance after (i) 4 days of waterlogging followed by 7 days of recovery at the germination stage and (ii) 8 days of waterlogging followed by 7 days of recovery at the seedling stage. Tolerance was measured against drained controls. GWAS was conducted using 3,522 high-quality DArTseq-derived SNPs, revealing five significant associations with five phenotypic traits indicating improved tolerance. Waterlogging tolerance was positively correlated with the formation of adventitious roots and higher dry masses. FGGY carbohydrate kinase domain-containing protein was identified as a candidate gene for adventitious rooting and mRNA-uncharacterized LOC111241851, Caffeoyl-CoA O-methyltransferase At4g26220 and MORC family CW-type zinc finger protein 3 and zinc finger protein 2B genes for shoot, root, and total dry matter production. Moderate to high broad-sense heritability was exhibited for all phenotypic traits, including seed emergence (81%), adventitious rooting (56%), shoot dry mass (81%), root dry mass (79%) and SPAD chlorophyll content (70%). The heritability estimates, marker-trait associations, and identification of sources of waterlogging tolerant germplasm from this study demonstrate high potential for marker-assisted selection of tolerance traits to accelerate breeding of climate-resilient mungbean varieties.

Water masses influence the variation of microbial communities in the Yangtze River Estuary and its adjacent waters.

The Yangtze River estuary (YRE) are strongly influenced by the Kuroshio and terrigenous input from rivers, leading to the formation of distinct water masses, however, there remains a limited understanding of the full extent of this influence. Here the variation of water masses and bacterial communities of 58 seawater samples from the YRE and its adjacent waters were investigated. Our findings suggested that there were 5 water masses in the studied area: Black stream (BS), coastal water in the East China Sea (CW), nearshore mixed water (NM), mixed water in the middle and deep layers of the East China Sea (MM), and deep water blocks in the middle of the East China Sea (DM). The CW mass harbors the highest alpha diversity across all layers, whereas the NM mass exhibits higher diversity in the surface layer but lower in the middle layers. Proteobacteria was the most abundant taxa in all water masses, apart from that, in the surface layer masses, Cyanobacterium, Bacteroidota, and Actinobacteriota were the highest proportion in CW, while Bacteroidota and Actinobacteriota were the highest proportion in NM and BS; in the middle layer, Bacteroidota and Actinobacteriota were dominant phylum in CW and BS masses, but Cyanobacterium was main phylum in NM mass; in the bottom layer, Bacteroidota and Actinobacteriota were the dominant phylum in CW, while Marininimicrobia was the dominated phylum in DM and MM masses. Network analysis suggests water masses have obvious influence on community topological characteristics, moreover, community assembly across masses also differ greatly. Taken together, these results emphasized the significant impact of water masses on the bacterial composition, topological characteristics and assembly process, which may provide a theoretical foundation for predicting alterations in microbial communities within estuarine ecosystems under the influence of water masses.

Contribution of expanded marine sulfur chemistry to the seasonal variability of dimethyl sulfide oxidation products and size-resolved sulfate aerosol

Abstract. Marine emissions of dimethyl sulfide (DMS) and the subsequent formation of its oxidation products methanesulfonic acid (MSA) and sulfuric acid (H2SO4) are well-known natural precursors of atmospheric aerosols, contributing to particle mass and cloud formation over ocean and coastal regions. Despite a long-recognized and well-studied role in the marine troposphere, DMS oxidation chemistry remains a work in progress within many current air quality and climate models, with recent advances exploring heterogeneous chemistry and uncovering previously unknown intermediate species. With the identification of additional DMS oxidation pathways and intermediate species that influence the eventual fate of DMS, it is important to understand the impact of these pathways on the overall sulfate aerosol budget and aerosol size distribution. In this work, we update and evaluate the DMS oxidation mechanism of the chemical transport model GEOS-Chem by implementing expanded DMS oxidation pathways in the model. These updates include gas- and aqueous-phase reactions, the formation of the intermediates dimethyl sulfoxide (DMSO) and methanesulfinic acid (MSIA), and cloud loss and aerosol uptake of the recently quantified intermediate hydroperoxymethyl thioformate (HPMTF). We find that this updated mechanism collectively decreases the global mean surface-layer gas-phase sulfur dioxide (SO2) mixing ratio by 40 % and enhances the sulfate aerosol (SO42-) mixing ratio by 17 %. We further perform sensitivity analyses exploring the contribution of cloud loss and aerosol uptake of HPMTF to the overall sulfur budget. Comparing modeled concentrations to available observations, we find improved biases relative to previous studies. To quantify the impacts of these chemistry updates on global particle size distributions and the mass concentration, we use the TwO-Moment Aerosol Sectional (TOMAS) aerosol microphysics module coupled to GEOS-Chem and find that changes in particle formation and growth affect the size distribution of aerosol. With this new DMS-oxidation scheme, the global annual mean surface-layer number concentration of particles with diameters smaller than 80 nm decreases by 16.8 %, with cloud loss processes related to HPMTF being mostly responsible for this reduction. However, the global annual mean number of particles larger than 80 nm (corresponding to particles capable of acting as cloud condensation nuclei, CCN) increases by 3.8 %, suggesting that the new scheme promotes seasonal particle growth to these sizes.

Giant radio galaxies in the LOFAR deep fields

The reason why some radio galaxies (RGs) grow to form so-called giant radio galaxies (GRGs) with sizes $&gt;$ 700 kpc, is still unknown. In this study, we compare the radio, optical and environmental properties of GRGs with those of a control sample of smaller RGs we found in the three LOw-Frequency ARray (LOFAR) deep fields, namely the Bo\"otes, ELAIS-N1, Lockman Hole, for a total area of approx 95 deg$^2$. We inspected the LOFAR deep fields and created a catalogue of 1609 extended radio galaxies (ERGs). By visual inspection, we identified their host galaxies and spectroscopically or photometrically classified 280 of these as GRGs. We studied their properties, such as their accretion state, stellar mass and star formation rate (SFR) using deep optical and infrared survey data. Moreover, we explored the environment in terms of the surface number density of neighbouring galaxies within these surveys. Integrated flux densities and radio luminosities were also determined for a subset of ERGs through available survey images at 50, 150, 610, and 1400 MHz to compute integrated spectral indices. Considering the fraction of GRGs displaying an FRII morphology alongside the host galaxy properties, we suggest that GRGs consistently possess sufficient power to overcome jet frustration caused by the interstellar medium. Moreover, clear differences emerge in the environmental densities between GRGs and smaller RGs, using the number of neighbouring galaxies within 10 Mpc from the host galaxy as a proxy. GRGs preferentially reside in sparser environments compared to their smaller counterparts. In particular, only 3.6&lt;!PCT!&gt; of the GRGs reside within a 3D comoving distance of 5 Mpc from a previously reported galaxy cluster. We found that larger sources exhibit steeper integrated spectral indices, suggesting that GRGs are late-stage versions of RGs. These results suggest that GRGs are amongst the oldest radio sources with the most stable nuclear activity that reside in sparse environments.