PurposeThe most frequent primary site of sarcomas in gynecologic oncology is uterus (83%) followed by ovary (8%), vulva and vagina (5%). We present three cases of sarcomas at atypical locations.MethodRecords of cases were retrieved from electronic medical records, and telephonic follow-up was done to know their current status.ResultCase 1: A 26-year-old parous lady presented with complaint of recurrent vulvar mass. Biopsy at our institute revealed myxoid liposarcoma. Metastatic workup was negative. She underwent radical local excision with VY-plasty and bilateral ovarian transposition (BOT) followed by concurrent chemo-radiotherapy. She is disease free at 12 months. Case 2: A 29-year-old lady presented with large bleeding mass arising from right wall of vagina. Histopathology report of vaginal biopsy was high-grade leiomyosarcoma. MRI pelvis with thorax and abdomen scan, examination under anesthesia and cystoscopy revealed non-metastatic operable disease. She underwent radical hysterectomy with vaginectomy with BOT followed by pelvic radiotherapy. At 4-month follow-up, she presented with scalp lesion. Further workup revealed disseminated metastatic disease. She is on palliative chemotherapy at the time of submission or article. Case 3: A 54-year-old lady underwent evaluation for pain abdomen with contrast-enhanced computed tomography which revealed a large omental mass. She had past history of carcinoma cervix 6 years back treated outside with surgery and chemo-radiotherapy. Image-guided biopsy was reported as leiomyosarcoma. Metastatic workup showed no disease elsewhere. She underwent omental mass excision followed by chemotherapy. She is disease free at 13 months.ConclusionSurgery remains the mainstay of treatment in non-metastatic sarcomas. Long-term follow-up of patients is needed in view of their atypical presentation.
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