As the need to discovers new mineral deposits and occurrences has intensified in recent years, it has become increasingly apparent that we need to map potentials via integrated information on the basis of metallogeny. Occurrences of mineralization such as tungsten (W), tin (Sn), columbium (Nb), tantalum (Ta), gold (Au), copper (Cu), lead (Pb), zinc (Zn), manganese (Mn) and monazite (Mnz) have been discovered in Rwanda. The objective of this study was to present a regional quantitative mineral prospectivity mapping (MPM) of W, Sn and Nb-Ta mineralization in Rwanda using the random forest (RF) method on the basis of open source data, such as geological maps, Bouguer gravity anomalies, magnetic anomalies, Landsat 8 images, ASTER GDEM, Globeland30, and OpenStreetMap. In addition, a newly introduced interpolation–density–delineation (IDD) process was applied to deal with the blank (masked) areas in remotely sensed mineral alteration extraction. Additionally, a k2-fold cross-validation method was also proposed to obtain more reasonable test errors. Firstly, the metallogenic regularity of W, Sn and Nb-Ta in Rwanda was summarized with the help of articles online. Secondly, original geological, geophysical, and remote sensing data were utilized to generate secondary data. Specifically, the IDD process was applied subsequent to the directed principal component analysis method (DPCA) to reconstruct the alteration anomaly map, and a relevant dataset was formed by the combination of original and secondary data. Thirdly, specific predictor layers for W, Sn and Nb-Ta were selected from relevant data via spatial correlation with known deposits, respectively, and the predictive models were established. Finally, near 26,000 squares were zoned in Rwanda, and RF was optimized and applied, the k2-fold cross-validation method was utilized to assess test errors, metallogenic belts and prospective areas for W, Sn, and Nb-Ta were delineated on the basis of total mineralization potential map and likelihoods map. Results proved that the open source data online were valid for drawing a preliminary mineralization potential map. Furthermore, it was also shown that the IDD method is suitable for the postprocessing of masked alteration anomaly maps. Belt IV-4 in the northwest and belt IV-2, IV-1 in the middle-east of Rwanda, containing a number of prospective areas, possess considerable likelihoods of deposits, and mining in Rwanda is at its dawn, with potential worth expecting.
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