AbstractThe degree to which deformation and seismicity is focused on major mapped structures remains a key unknown in assessing seismic hazards and testing continental deformation models. Here we combine 208 Global Positioning System (GPS) velocities with 12‐track Interferometric Synthetic Aperture Radar (InSAR) rate maps to form high‐resolution velocity and strain rate fields for south‐central Tibet. Our results show that deformation is not evenly distributed across the region. We find a few zones with high strain rates, most notably the Yutian‐Zhongba strain rate zone. However, the average of the strain rates is similar within and outside the mapped fault zones. In addition, the slip rates are low on all the conjugate strike‐slip faults widespread in central Tibet. The observations are difficult to reconcile with time‐invariant block models or with continuum models that lack mechanisms for strain localization. Our results support arguments that the most robust estimates of seismic hazard should integrate seismicity catalogues, active fault maps, and geodetic strain rate models.