Purpose– The purpose of this paper is to investigate trends in the use of research methodologies and publications in manufacturing strategy (MS) literature across geographical regions and suggests possible future research opportunities.Design/methodology/approach– This literature review is based on a sample of 512 subject-relevant journal articles and uses content analysis as the primary method for data analysis. The paper investigates developments in the use of research methodologies – in terms of research design, data collection methods, country of data collection, sample size, respondent type, statistical techniques used and time horizon of studies; and publication trends in terms of authorship type, authorship collaboration, most prolific authors, top journals, most prolific universities, and citation analysis.Findings– Research in MS has substantially changed from conceptual quantitative to empirical quantitative designs. NA and Europe show a declining research interest. However, other regions of the world are consistently showing higher interest. Significant opportunities and synergies exist for collaborative research among regions.Research limitations/implications– Though the literature review is limited in its selection of articles and journals it sketches a picture that may surrogate the whole research community in MS.Practical implications– Trends in publications and use of research methodologies provide directions for designing research projects relevant to various geographical regions. This will help develop a holistic understanding of MS that is meaningful for managers of today’s organizations.Originality/value– This paper provides broader and deeper review of the MS literature. Complex patterns in data are revealed using cross-tabulations and advanced cross-tabulations that have not been performed in previous content-analysis–based literature reviews in MS. These patterns will help position future research studies.