Manhattan State Hospital Research Articles

CHOLESTEROL AND LECITHIN CONTENT OF THE BLOOD IN CRYPTOGENIC EPILEPSY

The etiology of many types of epilepsy is still unsolved. The term cryptogenic as used in this article defines cases in which there is no definite pathologic condition. 1 It may well be that some of the manifestations of this disease are of metabolic origin; therefore, an accumulation of biochemical data is of the utmost importance. Thus far few observations on cholesterol have been published. Perhaps the most comprehensive investigations are those carried out by Robinson, Brain and Kay 2 and by Osnato and his co-workers. 3 Although their findings are interesting, we considered further work necessary. This report presents observations on the occurrence of cholesterol and lecithin in the blood in forty-seven cases of epilepsy and in the spinal fluid in twenty cases. The patients were all inmates of the Manhattan State Hospital. The blood was drawn in the morning before breakfast. Cholesterol was determined according to the Myers

Tribute by Dr. Jacob Oshlag, member of board of visitors, manhattan state hospital

Tribute by Dr. Jacob Oshlag, member of board of visitors, manhattan state hospital

LECITHIN AND CHOLESTEROL IN CEREBROSPINAL SYPHILIS INCLUDING DEMENTIA PARALYTICA AND TABES

Studies of the occurrence of lecithin and cholesterol in the blood and spinal fluid of patients suffering from the various forms of syphilis of the central nervous system show very different results. Active interest in these substances during the past decade has made us feel more and more the necessity for additional investigation. We have now completed analyses in seventy-eight cases (including tabes, cerebrospinal syphilis and dementia paralytica). Though this is too small a number for conclusive deductions, the results may be helpful. The analytic methods employed were essentially those published in 1928 and 1929.1All our patients were inmates of the Manhattan State Hospital. The blood and spinal fluid were drawn in the morning before breakfast. We studied four groups of patients: Those suffering from cerebrospinal syphilis and dementia paralytica (untreated). Those affected with tabes (untreated). Those suffering from cerebrospinal syphilis, tabes and dementia paralytica at various stages

Optic Nerve Pallor without Functional Disturbances in Luetics

Among two thousand paretics, eighty-six had pallor of the optic disc, but of these, 73 had normal corrected vision. In 26 percent reduction of fields and vision supervened later. But in almost 50 percent, presenting the fundus picture of primary optic atrophy, no functional disturbances had occurred after two years. These cases were seen in the Manhattan State Hospital. Similar and related observations, previously reported, are here cited.

Book Review Operative Surgery . (Volume VI — The Final Volume.) Covering the Operative Technic involved in the operations of general and special surgery. By Warren Stone Bickham, M.D., F.A.C.S., Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York; Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400

Book Review Operative Surgery . (Volume VI — The Final Volume.) Covering the Operative Technic involved in the operations of general and special surgery. By Warren Stone Bickham, M.D., F.A.C.S., Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York; Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400

Book Review Operative Surgery. Covering The Operative Technic involved in the operations of general and special surgery . By Warren Stone Bickham, M.D., F.A. C.S. Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York. Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400 pages, with 6378 illustrations, mostly

Book Review Operative Surgery. Covering The Operative Technic involved in the operations of general and special surgery . By Warren Stone Bickham, M.D., F.A. C.S. Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York. Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400 pages, with 6378 illustrations, mostly

Book Review Operative Surgery . Volume 5 — Covering the operative technic involved in the operations of general and special surgery. By Warren Stone Bickham, M.D., F.A.C.S.; Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York; Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes, totalling approximately 5400 pages, with 6378

Book Review Operative Surgery . Volume 5 — Covering the operative technic involved in the operations of general and special surgery. By Warren Stone Bickham, M.D., F.A.C.S.; Former Surgeon in Charge of General Surgery, Manhattan State Hospital, New York; Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes, totalling approximately 5400 pages, with 6378

TREATMENT OF GENERAL PARALYSIS

In October, 1919, a definite plan for the treatment of patients with neurosyphilis was adopted at the Manhattan State Hospital, with the intention of treating a large number for a sufficient length of time to obtain data on which to base reliable conclusions concerning the results of treatment. Because of the irregularity in the progress of the parenchymatous form of neurosyphilis in different persons, it was fully appreciated at the outset that a large number of patients must be treated for a time longer than the ordinary period of remissions in untreated cases, in order to be certain that the periods of improvement were due to treatment and not to the usual remissions. The patients accepted for treatment must not be selected but should be taken in the order of their admission, with the fewest possible exceptions, because a group of selected patients would not be representative of the general

Book Review Operative Surgery . Covering The Operative Technic involved in the operations of general and special surgery. Volume 3 by Warren Stone Bickham, M. D., F. A. C. S., Former Surgeon in charge of General Surgery, Manhattan State Hospital, New York, Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400

Book Review Operative Surgery . Covering The Operative Technic involved in the operations of general and special surgery. Volume 3 by Warren Stone Bickham, M. D., F. A. C. S., Former Surgeon in charge of General Surgery, Manhattan State Hospital, New York, Former Visiting Surgeon to Charity and to Touro Hospitals, New Orleans. In six octavo volumes totaling approximately 5400

Book Review Operative Surgery . Covering the Operative Technic Involved in the Operations of General and Special Surgery. By Warren Stone Bickham, M.D., and Phar.M. (Tulane), M.D. (Columbia), F.A.C.S.; Former Surgeon in charge of General Surgery, Manhattan State Hospital, New York; Former Instructor in Operative Surgery, College of Physicians and Surgeons (Columbia University), in the New York Post-graduate Medical School

Book Review Operative Surgery . Covering the Operative Technic Involved in the Operations of General and Special Surgery. By Warren Stone Bickham, M.D., and Phar.M. (Tulane), M.D. (Columbia), F.A.C.S.; Former Surgeon in charge of General Surgery, Manhattan State Hospital, New York; Former Instructor in Operative Surgery, College of Physicians and Surgeons (Columbia University), in the New York Post-graduate Medical School

The Treatment of Neurosyphilis at the Manhattan State Hospital. (State Hosp. Quart., November, 1922.) Furman, I. J.

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The Manhattan Fire: Some Reflections

The serious outbreak of fire which occurred at the Manhattan State-Hospital, Ward's Island, New York, on February 18, resulting in the death of twenty-four patients and three nurses, recalls the terrible holocaust of Colney Hatch nearly twenty years ago. Although the Press reports which reached this country contained many inaccuracies, yet it is apparent that there are several features of similarity between the two occurrences.

THE NEUROSEROLOGICAL FINDINGS IN TABES, GENERAL PARESIS, CEREBROSPINAL SYPHILIS, AND OTHER NERVOUS AND MENTAL DISEASES

This communication is the record of a laboratory equipped for serological work. It does not concern itself with the post-mortem findings, nor does it attempt to discuss the clinical distinctions of the diseases scheduled. The material was obtained from the Neurological Institute and in a measure from the Manhattan State Hospital, Ward's Island. The interesting work of Plaut has shown the necessity of a more definite laboratory knowledge of tabes, general paresis and cerebrospinal lues. In the above mentioned work there is little to help one in the differentiation between difficult cases of paresis and cerebrospinal syphilis, nor do other writers shed much light on the situation from a laboratory standpoint. The material analyzed in this communication, 340 cerebrospinal fluids and as many serums, we have divided into four groups or types: The negative types. The positive types. The aberrant types. The post-therapeutic

THE CEREBRO-SPINAL FLUID; ITS CELLULAR ELEMENTS AND GLOBULIN CONTENT

I. The results obtained by the French method appear to show a fairly consistent increase in cells throughout this study. 2. Seventy-six cases of dementia paralytica out of seventy-seven showed a lymphocytosis. Differential counts did not aid materially towards diagnosis. One case of clinical paresis was cytologically negative. Three cases of tabes dorsalis were cytologically positive. Two cases of cerebral syphilis showed a slight increase in cells. Ninty-three per cent of the cases of dementia paralytica gave a positive increase in globulin. One case of tabes dorsalis and one of cerebral syphilis gave a negative globulin reaction. 3. Korsakoff’s psychoses show practically no increase in lymphocytes of albumin. 4. Eighty-nine per cent of the epileptics showed abnormal increase in lymphocytes, at the same time no case of epilepsy gave an increase in globulin. 5. The diagnostic value of lymphocytosis in spinal fluids in cases of manic depressive insanity and dementia præcox still remains unexplained although there is no reason why those individuals may not become infected with the syphilitic virus. The five cases which showed a positive cell count and a positive increase in globulin also gave a positive history of acquired syphilis. 6. Two of three cases of traumatic psychoses gave a lymphocytosis but a negative globulin reaction. 7. Four out of five cases of senile symmetrical atrophy gave negative results throughout. 8. Two out of four cases of cerebral arteriosclerosis of nonsyphilitic genesis gave a mild lymphocytosis but a negative butryic acid reaction. 9. Morphinism and acetanilidism gave a lymphocytosis without increase in the globulin content, except in one case where there was a question of paresis. I am indebted to the kindness of Dr. William Mabon, superintendent of Manhattan State Hospital, for the opportunity of making this study, and to Dr. George H. Kirby for his most valuable assistance and encouragement in the division of the work.

Book Review Diseases of the Nose, Throat and Ear . By Charles Huntoon Knight, A.M., M.D., Professor of Laryngology, Cornell University, etc.; and W. Sohier Bryant, A.M., M.D., Consulting Otologist, Manhattan State Hospital, etc. Second edition, revised, 239 illustrations. Philadelphia: P. Blakiston's Son & Co. 1909.

Book Review Diseases of the Nose, Throat and Ear . By Charles Huntoon Knight, A.M., M.D., Professor of Laryngology, Cornell University, etc.; and W. Sohier Bryant, A.M., M.D., Consulting Otologist, Manhattan State Hospital, etc. Second edition, revised, 239 illustrations. Philadelphia: P. Blakiston's Son & Co. 1909.

Hydrotherapy as Practiced in the Manhattan State Hospital

Hydrotherapy as Practiced in the Manhattan State Hospital

HYDROTHERAPY AS PRACTICED IN THE MANHATTAN STATE HOSPITAL

Through the courtesy of Dr. William Mabon, superintendent and medical director, and Miss Townsend, superintendent of nurses, we are enabled to give the following description of methods used in the hydrotherapy room of the Manhattan State Hospital on Ward's Island, N. Y.

Diseases of the nose, throat and ear: By Charles Huntoon Knight, A. M., M. D., Professor of Laryngology, Cornell University Medical College, and W. Sohier Bryant, A. M., M. D., Consulting Otologist, Manhattan State Hospital. Second Edition. Cloth. Pp. 609, with 239 illustrations. Price, $4.50 net. Philadelphia: P. Blakis‐ton's Son & Co., 1909

Diseases of the nose, throat and ear: By Charles Huntoon Knight, A. M., M. D., Professor of Laryngology, Cornell University Medical College, and W. Sohier Bryant, A. M., M. D., Consulting Otologist, Manhattan State Hospital. Second Edition. Cloth. Pp. 609, with 239 illustrations. Price, $4.50 net. Philadelphia: P. Blakis‐ton's Son & Co., 1909

THE INTRA-ABDOMINAL ADMINISTRATION OF OXYGEN

Clinical Professor of Surgery, New York Polyclinic Medical School and Hospital; Consulting Surgeon, Manhattan State Hospital; Surgeon, New York Skin and Cancer Hospital: Associate Surgeon, Woman's Hospital.

Book Review A Textbook of Operative Surgery, Covering the Surgical Anatomy and Operative Technic involved in the Operations of General Surgery. Designed for Practitioners and Students . By Warren Stone Bickham, M.D., Phar.M., Junior Surgeon, Touro Hospital, New Orleans; late Surgeon to Manhattan State Hospital, New York; late Assistant Instructor in Operative Surgery, College of Physicians and Surgeons, New York,

Book Review A Textbook of Operative Surgery, Covering the Surgical Anatomy and Operative Technic involved in the Operations of General Surgery. Designed for Practitioners and Students . By Warren Stone Bickham, M.D., Phar.M., Junior Surgeon, Touro Hospital, New Orleans; late Surgeon to Manhattan State Hospital, New York; late Assistant Instructor in Operative Surgery, College of Physicians and Surgeons, New York,