Abstract. Nugroho GD, Wiraatmaja MF, Pramadaningtyas PS, Febriyanti S, Liza N, Naim DM, Ulumuddin YI, Setyawan AD. 2020. Review: Phytochemical composition, medicinal uses and other utilization of Nypa fruticans. Bonorowo Wetlands 10: 51-65. Nypa fruticans Wurmb or “nipa/nipah” is a palm plant in mangrove ecosystems along tropical and subtropical river estuaries affected by tides. Nipa has a high abundance in the mangrove forest ecosystem. Therefore, knowledge and utilization of this nipa plant need to be sought and examined more deeply to optimize its utilization. This review aims to find out the phytochemical composition, medicinal uses, and other utilization of nipa plants. The main phytochemical composition of nipa is polyphenols, phenolics, alkaloids, tannins, flavonoids, and saponins. However, other chemical compounds such as ethyl acetate, chloroform, hexane, triterpenoids, phenol hydroquinone, diterpenes, and steroids are still available. The many chemical compounds in nipa can be used as raw materials in a product, especially in modern medicines. Based on people's beliefs in several tropical countries that nipa has the potential of herbal medicine to treat fever, gout, kidney stones, energy booster, aid digestion, as a cure for certain chronic diseases and metabolic syndromes such as diabetes and hypertension, treat asthma, leprosy, tuberculosis, sick throat, liver disease, snakebite, as a pain reliever, and also be used as a sedative and able to expel excess wind in the body. Then in the pharmacological aspect, nipa has antioxidant, antidiabetic, antimicrobial (antifungal and antibacterial), anticancer, anti-inflammatory, antinociceptive, antihyperglycemic and analgesic activities. In addition to other benefits outside of drugs, nipa is used as a roof for houses, cattle pens, huts in the garden, broomsticks, handicrafts, fishing gear, food and drink sources, and sources of renewable fuel.
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