Mandibular Retrognathism Research Articles

Evaluation of use of distraction osteogenesis in mandibular retrognathia and its effect on soft and hard tissues and airway.

Objectives:Bone distraction is the process of new bone formation between the surfaces of bone segments gradually separated by incremental traction of soft tissues. These adaptive changes in the soft tissues allow for greater skeletal movements while minimizing the potential relapse. In this study, we are reporting our clinical experience with mandibular distraction used to achieve simultaneous skeletal and soft-tissue correction with distraction osteogenesis (DO).Methodology:A total of five patients who reported to the department for the treatment of mandibular deficiencies were selected. Cephalometric studies were done preoperatively and postoperatively for hard tissue assessment. Predefined reference points were used for the clinical evaluation for the evaluation of soft tissues. Results were compared between preoperative and 1st-, 3rd-, 6th-, and 12th-month postoperatively.Results:The clinical observations in our study showed that there is a remarkable improvement in the facial esthetics. Cephalometric analysis has shown lengthening of the mandibular corpus and increase in the height of the vertical ramus. Certain minimal complications have also been noted.Conclusion:Despite the few complications, DO has become a popular surgical modality due to its many advantages.

Orthodontic-surgical treatment of a patient with Marfan Syndrome and Obstructive Sleep Apnea Syndrome: a case report with a 9-year follow-up

ABSTRACT Marfan’s (MFS) syndrome is characterized by a defect in the connective tissue, which affects multiple organic systems. Therefore, the management of these patients requires a multidisciplinary approach. This case reports the orthodontic-surgical treatment of a patient who presented both Marfan’s and obstructive sleep apnea syndrome. Patient had malocclusion, TMJ clicking, vertical maxillary excess, mandibular retrognathia, severe esthetic compromise, signs and symptoms of obstructive sleep apnea syndrome, as well as alterationsin joints, cardiovascular and respiratory systems. He was treated with bimaxillary surgery aimed to enhance esthetics, occlusion and address the obstructive sleep apnea syndrome. The clinical results show that a desirable functional occlusion was achieved and both patient’s facial esthetics and quality of life were significantly improved. After a 9-year follow-up period, these pleasing features were maintained. The diagnosis and management of Marfan’s patients is challenging and require multidisciplinary follow-up.

Two middle-aged cases of deep overbite without molar support treated by orthognathic surgery

IntroductionPatients with severe overbite in middle age often undergo prosthetic treatment without a diagnosis of dentofacial deformity, but soft tissue trauma can occur in such patients due to the lack of inter-occlusal space. Comprehensive surgical orthodontic treatment and prosthetic treatment are indicated to correct the overbite and soft tissue injury for such patients. Presentation of caseWe report the cases of two middle-aged patients with dentofacial deformity and severe overbite without molar support. In both cases, prosthetic treatment had been performed for many years without any improvement of the occlusion. Case 1: A 47-year-old Japanese man had a maxillary incisor protrusion and reduced lower anterior facial height profile with the left mandibular molars lost due to periodontal disease. After preoperative orthodontic treatment and occlusal elevation in the molar teeth using an implant prosthesis, a sagittal split ramus osteotomy (SSRO) was performed. Case 2: A 57-year-old Japanese woman had mandibular retrognathia with maxilla and mandibular-arch length discrepancy. The left mandibular molars needed to be extracted due to periodontal disease. After preoperative orthodontic treatment and reconstruction of the molar occlusion using an implant prosthesis, three-segment Le Fort I osteotomy and SSRO were performed. DiscussionMalocclusion with dentofacial deformity is a risk factor for severe deep overbite or other occlusion collapse. ConclusionIn middle-aged patients with deep overbite with missing molar teeth, we should consider both prosthodontic treatment and comprehensive dental therapy, including orthognathic surgery.

Relationship between skeletal Class II and Class III malocclusions with vertical skeletal pattern.

ABSTRACTObjective: The purpose of this study was to establish the association between sagittal and vertical skeletal patterns and assess which cephalometric variables contribute to the possibility of developing skeletal Class II or Class III malocclusion. Methods: Cross-sectional study. The sample included pre-treatment lateral cephalogram radiographs from 548 subjects (325 female, 223 male) aged 18 to 66 years. Sagittal skeletal pattern was established by three different classification parameters (ANB angle, Wits and App-Bpp) and vertical skeletal pattern by SN-Mandibular plane angle. Cephalometric variables were measured using Dolphin software (Imaging and Management Solutions, Chatsworth, Calif, USA) by a previously calibrated operator. The statistical analysis was carried out with Chi-square test, ANOVA/Kruskal-Wallis test, and an ordinal multinomial regression model. Results: Evidence of association (p< 0.05) between sagittal and vertical skeletal patterns was found with a greater proportion of hyperdivergent skeletal pattern in Class II malocclusion using three parameters to assess the vertical pattern, and there was more prevalent hypodivergence in Class III malocclusion, considering ANB and App-Bpp measurements. Subjects with hyperdivergent skeletal pattern (odds ratio [OR]=1.85-3.65), maxillary prognathism (OR=2.67-24.88) and mandibular retrognathism (OR=2.57-22.65) had a significantly (p< 0.05) greater chance of developing skeletal Class II malocclusion. Meanwhile, subjects with maxillary retrognathism (OR=2.76-100.59) and mandibular prognathism (OR=5.92-21.50) had a significantly (p< 0.05) greater chance of developing skeletal Class III malocclusion. Conclusions: A relationship was found between Class II and Class III malocclusion with the vertical skeletal pattern. There is a tendency toward skeletal compensation with both vertical and sagittal malocclusions.

Association of Myo1h Gene Polymorphism in Mandibular Retrognathism in South Indian Dravidian Population

Association of Myo1h Gene Polymorphism in Mandibular Retrognathism in South Indian Dravidian Population

Association between normative and perceived esthetic results after treatment of mandibular retrognathism

Abstract Introduction This cross-sectional study aimed to associate the normative cephalometric results of mandibular retrognathism treatment with patient perception on the esthetic improvement of facial profile. Objective this cross-sectional study aimed to associate the normative cephalometric results of mandibular retrognathism treatment with patient perception on the esthetic improvement of facial profile. Material and method The normative cephalometric results were obtained from lateral cephalometric radiographs of a sample of 24 Class II malocclusion patients in the pubertal growth spurt. Such patients were treated with a mandibular advancement device and evaluated by comparing pre- and post-treatment variables. The same radiographs were used to produce standardized black silhouettes that were randomly arranged. Patients were instructed to choose their preferred profile and indicate the changes perceived using a 7-point Likert scale. The data were compared with cephalometric results using a mixed-model methodology for time-repeated measures, Student’s t-test, and t-test for heterogeneous variances, at 5% significance level. Result A rate of 75% of patients preferred post-treatment silhouettes and changes were perceived regardless of the choice of either pre- or post-treatment profile. There was no significant difference between the cephalometric variables of the tracings that produced the silhouettes considered better or worse after the evaluation. Conclusion There was no association between the cephalometric results after treatment and the perception of esthetic improvement by patients treated for mandibular retrognathia.

Twin block appliance: Effect on pharyngeal airway

Background: Mandibular retrusion is the main cause of Skeletal Class II malocclusion characterized by skeletal retrusion of mandible with skeletal or dentoalveolar protrusion of maxillary.&#x0D; Objectives: This study was conducted to evaluate effect of treatment with twin-block appliances on pharyngeal dimensions.&#x0D; Methodology: This study was conducted in in the Department of Orthodontics &amp; Dentofacial Orthopedics in Kathmandu Medical College. Twenty patients of age group 7 to 14 years with skeletal class II malocclusion with mandibular retrusion were selected. Variables evaluated were depth of nasopharynx; height of nasopharynx; depth of oropharynx; depth of hypopharynx; soft palate length; soft palate thickness and soft palate inclination. The lateral cephalograms were obtained for all subjects before the start of treatment and after a follow-up period of approximately three months in treatment.&#x0D; Results: Results showed that depth of nasopharynx increased by 1 mm, height of nasopharynx increased by 0.78 mm, depth of nasopharynx increased by 1.97 mm, depth of hypopharynx increased by 0.79 mm, soft palate length decreased by 4 mm, soft palate thickness increased by 2 mm and soft palate inclination decreased by 7.01 mm. The results for depth of pharynx and soft palate thickness were statistically significant.&#x0D; Conclusion: This study concluded that the use of twin block appliance for class II patients corrects sagittal dimension of oropharynx and hypopharynx. Early intervention for mandibular retrognathism in class II malocclusion helps enlarge the airway dimensions and decrease potential risk of obstructive sleep apnea syndrome for growing patients in the future.

Nuevo aparato ortopédico fijo para el tratamiento de maloclusiones clase II división 1. Descripción de un caso

Antecedentes: La corrección temprana de las maloclusiones clase II asociadas a retrognatismo mandibular se logra mediante avance mandibular sostenido y continuo que no requiera colaboración del paciente. Objetivo: Describir un caso de maloclusión tratado con un nuevo arco de adelantamiento mandibular fijo (AAMF). Descripción del caso: El AAMF se usó en una paciente de 11 años y 6 meses, clase II esquelética división 1, con retrognatismo mandibular y mordida profunda. Resultados: Al año de tratamiento había cambios estéticos y funcionales. El ángulo ANB disminuyó (6,6° a 5,0°). La longitud efectiva mandibular (Co-Gn) aumentó (96,1 mm a 103,4 mm). La inclinación de incisivos superiores pasó de 28,0° a 28,4°. Los incisivos inferiores se proinclinaron levemente (26,2° a 30,9°). Las cefalometrías después de la fase de ortodoncia mostraron medidas esqueléticas estables: ANB pasó de 5,0° a 5,1° y Co-Gn se mantuvo en 103,4°. Hubo cambios en la posición de los incisivos: superiores retroinclinaron de 28,4° a 22,5° e incisivos inferiores pasaron de 30,9° a 28,2°. Conclusión: El AAMF representa una alternativa de tratamiento en denticiones mixta y permanente temprana: Por ser fijo, permite lograr avance mandibular sostenido y continuo, sin requerir colaboración del paciente, y durante el tiempo necesario para generar cambios. Por la sencillez de su estructura (maxilar cementado solo en los primeros molares maxilares), avanza la mandíbula sin fijarse a ella cada vez que el paciente cierra la boca. Además es sencillo de elaborar, cementar, activar, limpiar y mantener en boca.

Cephalometric Findings in Nine Individuals With Richieri-Costa-Pereira Syndrome.

The Richieri-Costa-Pereira syndrome (RCPS) is an autosomal-recessive acrofacial dysostosis caused by mutations in EIF4A3, characterized by mandibular cleft comprising other craniofacial anomalies and limb defects such as cleft palate/Robin Sequence, microstomia, absence of mandibular central incisors, minor ear anomalies, clubfeet and first and 5 ray defects. The findings from this study are useful for better understanding the morphological consequences of disorders of EIF4A3, and having a better picture of the anatomic characteristics of the syndrome for a better therapeutic planning. Twenty-four angular and linear variables were measured to assess anteroposterior and vertical (superior-inferior) position of the cranial base, maxilla, mandible, and facial profile. The cephalometric radiographic analysis was performed on 9 individuals with RCPS, obtained at a mean age of 10.3 years, and compared with randomly selected age-matched 9 controls, without clefts and with well-balanced faces, with mean age of 10.6 years (both groups range 8.1 to 13.7 years). t test was used for analysis of means and Levene test for equality of variances. The syndrome group presented severe mandibular hypoplasia and retrognathism (P = 0.009, P = 0.001), greater facial convexity (N'PnPog and N'SnPog, P < 0.05) in syndrome group compared with the control group (P = 0.003, P = 0.004). In conclusion, in the RCPS group, most craniofacial defects affect the lower facial third, considering the severely affected mandible.

Three-dimensional volumetric analysis of condylar head and glenoid cavity after mandibular advancement

The aim of this study was to assess condylar resorption, spatial change in glenoid cavity, and its risk factors after mandibular advancement by three-dimensional volumetric analysis. Subjects consisted of 30 condyles of 15 patients diagnosed with mandibular retrognathism who underwent Le Fort I and bilateral sagittal split ramus osteotomy advancement. CBCT images were taken before surgery (T0), immediately after surgery (T1), and postoperatively at 6 months (T2) and 1 year (T3). Condylar resorption was observed in 21 condyles. The posterior was the most affected region, while the anterior was the least affected. The volume of the glenoid cavity was significantly increased after surgery regardless of the presence or absence of resorption. However, the cavity recovered close to its original volume over time. At 1 year after surgery, the volume was not significantly different from the preoperative volume. Counterclockwise rotation of the proximal segment was found to be a risk factor affecting resorption based on correlation analysis. Mandibular advancement appeared to generate excessive mechanical stress on the posterior condyle, and might be responsible for the resorption. Counterclockwise rotation might have added stress to the region. Articular spatial change was transient and did not appear to be related to condyle resorption.

Long-term stability of mandibular advancement with bilateral sagittal split osteotomy

IntroductionAim of this study was 1) to evaluate long-term dental/skeletal stability in patients with mandibular retrognathia corrected by BSSO, and 2) to examine factors associated with relapse. Materials and methodsSeventy-seven of initial 151 study cohort subjects who had undergone orthognathic surgery in 2007–2011 agreed to participate. Present paper presents data on dental/skeletal stability in 46 patients; 31 patients were excluded because of missing calibration indicator in one of the patients' pre-operative cephalometric radiographs, or because of pregnancy. Pre-operative (T1), post-operative (T2) and long-term follow-up (T3) radiographs and patient's files were used in the study. ResultsBased on overjet measurements, mean mandibular advancement was 5.7 mm and mean relapse 0.1 mm. Mean pre-operative overbite was 5.4 mm, reduction at surgery 3.4 mm and mean relapse 1.1 mm, a statistically significant change. Mean mandibular advancement measured from condyle tognathion (Co-Gn) was 6.5 mm. Relapse in Co-Gn was 1.6 mm on average, i.e., about 25% of the advancement. Amount of advancement, fixation method, patient's age or gender or orthodontist/surgeon experience did not have influence on relapse. ConclusionsMandibular advancement with BSSO in healthy Class II patients is considered a stable procedure. 25% skeletal relapse was found with clinically non-significant dental changes.

Dentofacial Effects of Fixed Functional Appliances with or without Mini Screw Anchorage in the Treatment of Class II Division I Malocclusion: A Finite Element Analysis.

This study aimed to examine the biomechanical effects of the fixed functional appliances reinforced with miniscrews by finite elements analysis over the cranial and facial bones, temporomandibular joint, and maxillary-mandibular teeth, which are used for the treatment of Class II division 1 malocclusions characterized as mandibular retrognathia. Three-dimensional (3-D) models of the cranial, mandibular, and maxillary bones were purchased from a company that produces 3-D models of the bones. Simulations of Forsus, screwed Forsus, Twin-Force and screwed Twin-Force appliances were conducted on the 3 D models. The miniscrew was placed in the inter-radicular area between the upper canine and first upper premolar teeth. It was observed in the models that the first upper molar tooth was the most affected. The compressive stress was observed in the anterior area of the mandibular condyle neck in the Forsus appliances; however, it was observed in the posterior area of the mandibular condyle neck in Twin-Force appliances. It was observed that molar distalization and expansion decreases in the functional appliances with the support of miniscrew. The highest tension rates were determined in the areas of condylar and articular discs.

Three-dimensional computed tomography analysis of mandibular morphology in patients with facial asymmetry and mandibular retrognathism.

The purpose of this study was to analyze the morphologic features of skeletal units in the mandibles of patients with facial asymmetry and mandibular retrognathism using cone-beam computed tomography. The subjects consisted of 50 adults with facial asymmetry and mandibular retrognathism, divided intothe symmetry group (n=25) and the asymmetry group (n=25) according to the degree of menton deviation. Three-dimensional computed tomography scans were obtained with cone beam computed tomography. Landmarks were designated on the reconstructed 3-dimensional images. Linear and volumetric measurements were made on the mandibles. In the asymmetry group, the lengths of condylar, body, and coronoid units were shorter, and condylar width was narrower on the deviated side than on the nondeviated side (P<0.01). The lengths of angular and chin units were not significantly different between the deviated and nondeviated sides (P>0.05). Hemimandibular, ramal, and body volumes were less on the deviated side than on the nondeviated side (P<0.01). Condylar, body, and coronoid units contribute to mandibular asymmetry in patients with facial asymmetry and mandibular retrognathism.

Study of condylar positional changes after sagittal split osteotomy for mandibular advancement: A prospective cohort study

PurposeTo analyse the possible morphologic and positional changes of the mandibular condyles after orthognathic surgery. Material and MethodsA prospective cohort study was performed. Patients with mandibular retrognathism were surgically treated to advance the mandible. The study group included seventeen patients (34 condyles) treated with sagittal split osteotomies alone (4 patients) or in combination with maxillary osteotomies (13 patients). Only condyles located on the mandibular side that advance during surgery were studied, therefore only 25 condyles entered this prospective study. Beside it, a group of 6 patients undergoing maxillary surgery as only procedure, maxillary group, was also studied to determinate the influence of maxillary surgery on condylar displacement. Computed tomographies and lateral cephalometric radiographs were performed two weeks before surgery and one year after the surgical procedures. Different variables which analyse the position and morphology of the mandible were studied. The data obtained were analysed statistically by computing R2 values. ResultsIn the maxillary group they were small displacements in magnitude and not significant. In the study group, 8 condyles showed morphological changes with alteration on reference points. In the remainder 17 condyles different displacements were noted after surgery. Several of these positional changes were predictable and did not affect postoperative mandibular stability. Conclusionscondylar displacements that occur after sagittal split osteotomies for mandibular advancement show significant correlation with the degree of mandibular advancement and can be defined by mathematical formulae. Maxillary osteotomies do not seem to influence condylar position when bimaxillary procedures take place.

Mandibular retrognathia correction using a fixed sagittal guidance appliance individually manufactured by selective laser melting manufacturing technology

PurposeDigitalization and additive manufacturing now play an important role in the manufacturing of medical and dental products. The purpose of this paper is to present the results of the treatment of skeletal Class II malocclusion in a growing patient using fixed sagittal guidance (FSG) appliance manufactured by digital and fast procedure by selective laser melting.Design/methodology/ApproachThis study present the case of a 14-year-old boy with a convex profile owing to a retrognathic mandible, an overjet (8 mm), a deep overbite (7 mm), a Class II canine, a molar relationship on both sides and an accentuated lower curve of Spee. The lateral cephalogram showed a skeletal Class II discrepancy with mandibular retrognathia, skeletal deep bite, reduced lower anterior facial height and proclined upper incisors. Treatment using FSG and fixed orthodontic appliance was performed within 15 months.FindingsThe final results show a well-balanced face and a nice profile. Protrusion of the maxillary anterior teeth was corrected, and a Class I molar relationship was achieved with proper overjet and overbite.Research limitations/implicationsThe results from the proposed method are promising, although long-term results with a large group are not yet available.Practical implicationsUsing an individually made FSG appliance from biocompatible material and an individualized treatment plan, an effective result in treating Class II malocclusion due to retrognathic mandible with favorable dentofacial effects has been achieved.Originality/valueThis is the first paper describing the use of additive manufacturing for orthodontic appliances in Slovenia.

Influential factors of esthetic evaluation of mandibular prominence in orthodontic patients

Objective To explore the influential factors of esthetic evaluation of mandibular prominence by orthodontic patients from two dimensions (ideal value and tolerance range). Methods 226 orthodontic patients were investigated by an electronic questionnaire of esthetic evaluation of mandibular prominence. Binary logistic regression was adopted to analyze the influential factors. Results The tolerable boundary value for female mandibular retrognathism was affected by age (OR1.360) and orthodontic history (OR2.849). The tolerable boundary value for female mandibular prognathism and male mandibular retrognathism were found to be affected by orthodontic history (OR2.557 and 2.845, respectively). The tolerable boundary value for male mandibular prognathism was affected by age (OR1.347) and orthodontic history (OR2.310). The ideal value of male mandibular prominence was affected by age (OR1.420). Conclusions Orthodontic patients’ esthetic evaluation of mandibular prominence is influenced by age and treatment condition, but not by sex, education level, marital status and personal profile. Key words: Facial profile; Mandibular prominence; Esthetic evaluation; Facial convexity angle

Relationship between matrilin-1 gene polymorphisms and mandibular retrognathism.

Mandibular retrognathism is a type of malocclusion that refers to an abnormal posterior position of the mandible as a result of a developmental abnormality. From the literature, it is evident that the mandibular growth pattern is determined by the intramembranous ossification of the mandibular body and endochondral ossification of the condyle. Matrilin-1 is a cartilage extracellular matrix protein, and matrilin-1 gene (MATN1) polymorphisms have been found to be involved in dental malocclusions of humans. In this study, we aimed to examine the association between MATN1 polymorphisms and the risk of mandibular retrognathism, in a case-control study with a South Indian population. Eighty-one patients with mandibular retrognathism (SNB,<78°) and 71 controls having an orthognathic mandible (SNB, 80°±2°) were recruited. In both the patient and control groups, subjects with an orthognathic maxilla (SNA, 82°±2°) were included. Three single nucleotide polymorphisms of the MATN1 gene (rs1149048, rs1149042, and rs1065755) were genotyped using polymerase chain reaction-restriction fragment length polymorphism. The statistical association analysis was performed using the chi-square test. Pair-wise linkage disequilibrium was computed, and haplotypes were compared between subjects and controls. Nonparametric tests were used to compare cephalometric measurements between groups. No polymorphic site deviated from Hardy-Weinberg equilibrium in the controls. The rs1149042 genotypes and alleles were found to be associated with reduced risk of mandibular retrognathism. Furthermore, rs1149042 genotypes were associated with mandibular measurements (SNB and ANB). There was no strong and consistent linkage disequilibrium linkage disequilibrium across two different single nucleotide polymorphisms and haplotypes were not associated with mandibular retrognathism. The results of our study suggest an association between the MATN1 gene polymorphisms and mandibular retrognathism.

One-stage technique for sagittal split ramus osteotomy combined with mandibular angle ostectomy

Bilateral sagittal split ramus osteotomy (BSSRO) is commonly used to correct mandibular prognathism or retrognathism. Patients with mandibular prognathism or retrognathism may also present with a prominent mandibular angle. In this paper, we share our experience on BSSRO with mandibular angle resection. Eleven patients who were treated from July 2014 to December 2016 were included in this study. The mandibular angle was resected through the medial side of the mandible after BSSRO. The mandibular angle measurements of the patients changed significantly after surgery (p < 0.05). Unanticipated fractures and mandibular hematoma did not occur. Therefore, BSSRO combined with mandibular angle ostectomy through the medial side of the mandible can be used to safely and effectively correct facial deformity.

Pharyngeal Airway Space Changes After Condylar Replacement and Mandibular Advancement Surgery

The aim of this study was to examine the total volume and cross-sectional areas of the pharyngeal airway after bilateral condylar replacement and mandibular advancement surgery. A total of 137 patients (126 women and 11 men) underwent bilateral temporomandibular joint total joint replacement performed by 1 surgeon. A subsample of 30 patients who underwent condylar replacement and only mandibular advancement were evaluated for impact on the airway. Measurements were taken preoperatively, postoperatively, and at a follow-up 1year after surgery on cone beam computed tomography scans. InVivoDental 3-dimensional imaging (Anatomage, San Jose, CA) was used to measure airway space regarding total volume (in cubic centimeters); minimum cross-sectional area (in square millimeters); minimum cross sections of the first, second, and third cervical vertebrae; and whether the patient had mandibular retrognathia before surgery.Asecond operator was used to test for interoperator error. Descriptive and bivariate statistics were computed, and the P value was set at .05. There was a significant increase in all measurements at the follow-up visit compared with the preoperative visit. There were no significant differences between groups based on simultaneous Le Fort I surgery, mandibular retrognathia, and gender. However, there were statistically significant differences in cross sections 1 and 2, as well as minimum cross-sectional area, regarding age. Condylar replacement and mandibular advancement have a significant association with an increase in airway space. The intraclass correlation coefficient showed excellent agreement between interoperator measurements. Patients undergoing bilateral temporomandibular joint replacement and mandibular advancement surgery showed an increase in pharyngeal airway space at a 1-year follow-up. In this study, age was significantly associated with the cross-sectional areas of the airway, with older patients having smaller values.

Assessment of mandibular retrognathism and maxillary prognathism as contributory factors for skeletal Class II malocclusion: A cephalometric study

Aim: The aim of this study is to evaluate the skeletal factor (maxillary excess and/or mandibular deficiency) contributing for the skeletal Class II malocclusion. Materials and Methods: Lateral cephalograms of 100 individuals (50 males and 50 females) in the age group of 18–30 years, having skeletal Class II malocclusion with ANB of more than 4, were evaluated. The parameters to be used for prediction of maxillary prognathism include linear measurement of Nasion perpendicular to point A, and for the mandibular retrognathism, it is linear measurement of Nasion perpendicular to Pogonion, as suggested by Burstone analysis. Results: The 34% of the studied sample size had the Class II skeletal pattern (ANB >4), but their observed values for the maxilla and the mandible (with respect to the cranium) were in the normal range according to Burstone's cephalometric norms. Mandibular retrognathism with 68% prevalence in the final studied sample size is the major contributory factor for the skeletal Class II malocclusion which is followed by maxillary prognathism with 27% prevalence in the studied sample size, and the last contributory factor is the combination of the above two which accounts for the 5% of the studied sample size. Conclusion: The cephalometric study of skeletal Class II participants suggests mandibular retrognathism to be the major component in the given sample size. The other important conclusion from this study is that the ANB angle is not a reliable indicator to assess the skeletal malocclusion.