Objective The purpose of this study was to observe the dental arch asymmetry in 12-year-olds with normal occlusion during the early permanent dentition stage. Methods Ninety-two 12-year-old students (46 males and 46 females) who had normal occlusion during early permanent dentition were selected from a junior high school in Tangshan, China. Once per year for three consecutive years, a dental cast was obtained from each subject, and the cast was scanned with a 3D digital scanner (R700 3D). The median palatal plane (MPP) and transverse palatal plane (TPP) were used as the reference plane for the transverse and anteroposterior measurements, respectively. Results Most of the dental arch asymmetry indicators decreased with age, but these differences were not statistically significant. The values of the midincisal edge of the upper central incisors (U1), midincisal edge of the upper lateral incisors (U2), upper canine cusp tip (U3), upper first premolar buccal cusp tip (U4), upper second premolar buccal cusp tip (U5), upper first molar mesiobuccal cusp tip (U6MB), and upper first molar distobuccal cusp tip (U6DB) to the TPP were 0.019 mm, 0.279 mm, 0.017 mm, 0.016 mm, 0.016 mm, 0.027 mm, and 0.200 mm, respectively; these values were larger in males than in females (P < 0.05). The values of 2–5, 6MB, and 6DB-TPP were 0.154 mm, 0.102 mm, 0.119 mm, 0.259 mm, 0.206 mm, and 0.123 mm, respectively, larger in the mandibular than in the maxillary dental arch (P < 0.05). The values of the midincisal edge of the lower central incisors (L1), midincisal edge of the lower lateral incisors (L2), lower canine cusp tip (L3), lower first premolar buccal cusp tip (L4), lower second premolar buccal cusp tip (L5), lower first molar mesiobuccal cusp tip (L6MB), and lower first molar distobuccal cusp tip (L6DB) to the MPP were 0.399 mm, 0.197 mm, 0.258 mm, 0.248 mm, 0.214 mm, 0.575 mm, and 0.531 mm, respectively, larger than L1-5, L6MB, and L6DB-TPP (P < 0.05). Conclusion The asymmetry of the dental arch in 12-to-15-year-olds with normal occlusion did not change significantly with age. The anteroposterior asymmetry of the maxillary dental arch is larger in males than in females. With the exception of the central incisor, the anteroposterior asymmetry of the mandibular dental arch is larger than that of the maxillary dental arch. The transverse asymmetry of the mandibular dental arch is larger than the anteroposterior asymmetry.
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