C2H5 In 1937, Erdtman and Lofgren showed that a series of acetanilid derivatives displayed local anesthetic faculties. In the course of continued investigation of substances possessing local anesthetic properties, Lofgren and Lundquist in 1943 synthesized omega diethylamino-2.6dimethylacetanilid called Xylocaine or lidocaine, and indicated that this compound might be of clinical importance.3 Structurally Xylocaine is:
Read full abstract