Management Of Mental Health Disorders Research Articles

APPLICATION OF MEDICINAL PLANTS IN MENTAL HEALTH CARE: A COMPREHENSIVE REVIEW

Ayurveda, an ancient Indian system of medicine, offers a rich repository of medicinal plants with therapeutic potential for various health conditions, including mental health disorders. This review aims to explore the application of Ayurvedic medicinal plants in mental health care. A comprehensive search was conducted in electronic databases, including PubMed, Scopus, and Google Scholar, and Various Ayurvedic texts. Several Ayurvedic medicinal plants, such as Brahmi (Bacopa monnieri), Ashwagandha (Withania somnifera), Jatamansi (Nardostachys jatamansi), and Shankhpushpi (Convolvulus pluricaulis), have demonstrated significant neuroprotective, anxiolytic, antidepressant, and cognitive-enhancing properties in preclinical and clinical studies. The mechanisms of action of these plants involve modulation of neurotransmitter levels, antioxidant effects, and anti-inflammatory properties. Moreover, Ayurvedic formulations, such as Sarasvata Churna, Smriti Sagar Ras, and Brahma Rasayana, have been traditionally used to improve memory, cognition, and overall mental well-being. Despite the promising evidence, further research is warranted to elucidate the precise mechanisms of action and establish the safety and efficacy of these plants in mental health disorders. In conclusion, Ayurvedic medicinal plants offer a valuable adjunctive or alternative approach to the management of mental health disorders. Integrating Ayurveda into mainstream mental health care could provide holistic and personalized treatment options for patients.

Common Mental Health Disorders and Their Current Prescription Patterns in Saudi Arabia's Primary Healthcare Settings.

Background The mental healthcare program is widely implemented in primary healthcare settings in Saudi Arabia. It consisted of early screening and management of mental health disorders associated with chronic health conditions. Family physicians are authorized to prescribe selective serotonin reuptake inhibitors (SSRIs) for early management of mental health disorders in primary healthcare centers (PHCs).The aim of the study is exploring the prevalence of various types of mental health disorders and to assess the prescribing pattern of SSRIs in PHCs. Materials and methods A cross-sectional study based on the data from electronic health records, telephone interviews, and prescriptions of individuals administered SSRIs at PHCs. Results Among 219 patients visiting PHCs, 67.6%were female participants. Forty-four percent of the patients were 20-30 years oldand 61.2%of them received SSRImedications. The most prevalent chronic condition was diabetes (22.5%) followed by hypertension (20.5%) and asthma (6.4%). The most prevalent mental disorder was major depressive disorder (MDD; 78.1%), followed by anxiety disorder (7.3%), panic disorder (6.4%), and MDD with anxiety disorders (5.5%). Conclusion Implementing mental healthcare programs in PHCsis believed to promote population health. MDDwas the predominant mental health disorder among patients visiting PHCs, and SSRIs were the most prescribed medications in this setting. This suggests that mental healthcare programs in PHCs are effective in improving mental health outcomes.

Perspectives of Patients with Mental Health Disorders on Integrating the Spirituality and Religion into Psychiatric Assessments: A Study in Iran

Background: In recent years, there has been a growing emphasis on exploring the influence of spirituality/religion on the management of mental health disorders. The aim of this study was to investigate the viewpoints of Iranian patients with mental health disorders regarding the incorporation of spirituality into their assessment. Methods: This cross-sectional study was conducted in 2021 at Iran University of Medical Sciences. Initially, a questionnaire was developed based on key spiritual concepts identified from a literature review. The content and face validity of the questionnaire were evaluated by an expert panel, and its reliability was assessed using Cronbach’s alpha coefficient. Data collection was carried out in the second phase, with the questionnaire consisting of 4 questions examining the patients’ perceived need and willingness for their therapist to explore their spiritual and religious dimensions. Data analysis was performed using appropriate statistical tests. Results: The questionnaire’s validity was confirmed, and its reliability was demonstrated with a Cronbach’s alpha value of 0.79. A total of 368 patients participated in the study. No significant associations were observed between the participants’ educational level, diagnosis type, gender, and the questionnaire scores. Approximately half of the patients with mental health disorders expressed a desire to incorporate spiritual assessments into their psychological evaluations, with most welcoming this integration. Conclusion: The findings of this study suggest that despite challenges and barriers, efforts should be made to integrate spiritual dimensions into the treatment of patients.

Do Boycotts Harm Retail Workers?

The aim of this study is to analyse the impact of boycotts on the mental health of retail workers in Malaysia. Specifically, the study examines the risk factors associated with mental health disorders among retail workers during boycotts. A convenience sampling technique was used to interview 350 retail workers in fast food restaurants in the Klang Valley. Participants completed a questionnaire based on the Beck Depression Inventory. The results of the study showed that the majority of scores fell between 17 and 20, indicating borderline clinical depression. Scores of 21-30 placed employees in the moderate depression category. Multiple regression analysis confirmed that fatigue or loss of energy, guilt, hopelessness or worthlessness were the main predictors of self-perceived work performance during the boycott among retail workers. This research provides new insights into the risk of psychological distress among retail workers during boycotts. These findings may suggest appropriate prevention and intervention strategies to reduce the burden of depression. The study provides new knowledge that may improve the understanding and management of mental health disorders among retail workers.

UK guideline on the transition and management of childhood liver diseases in adulthood.

Improved outcomes of liver disease in childhood and young adulthood have resulted in an increasing number of young adults (YA) entering adult liver services. The adult hepatologist therefore requires a working knowledge in diseases that arise almost exclusively in children and their complications in adulthood. To provide adult hepatologists with succinct guidelines on aspects of transitional care in YA relevant to key disease aetiologies encountered in clinical practice. A systematic literature search was undertaken using the Pubmed, Medline, Web of Knowledge and Cochrane database from 1980 to 2023. MeSH search terms relating to liver diseases ('cholestatic liver diseases', 'biliary atresia', 'metabolic', 'paediatric liver diseases', 'autoimmune liver diseases'), transition to adult care ('transition services', 'young adult services') and adolescent care were used. The quality of evidence and the grading of recommendations were appraised using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. These guidelines deal with the transition of YA and address key aetiologies for the adult hepatologist under the following headings: (1) Models and provision of care; (2) screening and management of mental health disorders; (3) aetiologies; (4) timing and role of liver transplantation; and (5) sexual health and fertility. These are the first nationally developed guidelines on the transition and management of childhood liver diseases in adulthood. They provide a framework upon which to base clinical care, which we envisage will lead to improved outcomes for YA with chronic liver disease.

Knowledge and Attitudes Regarding Depression Among a Sample of Iraqi Non-Psychiatric Nurses: A Cross-Sectional Study

Introduction Nurses, comprising the largest profession in healthcare, play a significant role in the identification and management of mental health disorders in hospitals. Objectives The study assessed the knowledge and attitudes of non-psychiatric nurses and their encounters with depressive patients throughout their careers. Methods This was a cross-sectional descriptive study with 400 non-psychiatric nurses from different hospitals in the Kurdistan Region of Iraq during October and November 2022. The independent Student's t-test, one-way analysis of variance, and binary logistic regression were used to assess possible factors associated with knowledge and attitude toward depression. Results In this study, 400 non-psychiatric nurses were examined, revealing a mean age of 31.57 ± 8.59 years. Their mean scores for knowledge and attitude toward depression were 5.41 out of a maximum of 11 (standard deviation 1.15) and 5.15 out of 18 (standard deviation 1.83), respectively. Notably, differences in mean knowledge scores were observed concerning participant marital status ( P = .044), while disparities in mean attitude scores are related to participant gender ( P = .010). Upon binary logistic regression analysis, none of the independent variables exhibited an association with good knowledge. Nevertheless, gender emerged as a significant factor influencing attitude toward depression (odds ratio: 0.51; 95% confidence interval: 0.30–0.86; P = .012). Subsequently, in the multivariate binary logistic regression analysis, gender sustained significance (adjusted odds ratio: 0.573; 95% confidence interval: 0.348–0.942; P = .028) as the key variable impacting attitudes toward depression among non-psychiatric nurses. Conclusion Based on the results of this study, nurses have insufficient awareness and management skills for depression. It has been experienced and reported that nurses lack knowledge and an attitude toward depression management. The study highlights a significant gap in nurses’ skills for managing depression, urging the immediate improvement of training programs. Customizing these programs to enhance nurses’ abilities in identifying and managing depression is crucial.

MT64 The Role of Digital Health Technologies in Out-of-Hospital Management of Mental Health Disorders in the UK

MT64 The Role of Digital Health Technologies in Out-of-Hospital Management of Mental Health Disorders in the UK

Qualitative Study of Perinatal Mental Health Services: Experiences and Perspectives of Health Workers and Patients

The perinatal period is a transitional period that is vulnerable to changes in women's relationships with partners, family, friends, and wider social networks. This study aims to determine how perinatal mental health services are based on the experiences of health workers and patients. This research is qualitative research with a case study design. The informants in this study were 6 informants, namely 2 health workers and 4 patients with a history of perinatal mental health disorders. The instruments used in this study were structured interview guidelines, interviews were conducted in health facilities and patients' homes. Thematic data analysis using the Collaizi protocol. Qualitative data from this study raised six themes, namely "symptoms of perinatal mental health disorders", "causes of perinatal mental health disorders", "management of mental health disorders", "prevention of perinatal mental health disorders", "barriers to perinatal mental health services", and "support". Pregnant, maternity and postpartum women are vulnerable to mental health problems, especially if a woman is faced with family neglect and lack of husband's support during pregnancy. It is important for health workers, especially midwives, to examine women's problems more comprehensively during antenatal care.

Plants and mental disorders: the case of Catalan linguistic area.

Introduction: Mental disorders are among the leading causes of ill-health and disability worldwide. Despite the disease burden they cause, including significant direct and indirect impacts on individual's health and major social and economic consequences in all countries of the world, it is still one of the most neglected areas of public health. In such a context, the medicinal plants traditionally used to pale these pathologies are presented as a promising tool for future drug development for the management of mental health disorders. The aim of the present study is to analyze the information about plant species used to treat mental disorders in the Catalan linguistic area (CLA) and compare these traditional uses with pharmacological literature in order to evaluate the most quoted taxa and their uses and to provide a basis for further research. Methods: Data have been recovered from the "Etnobotànica dels Països Catalans" webpage (https://etnobotanica.iec.cat/) and the meta-analytic work carried out in the present study covers 27 prospections performed in different territories between 1990 and 2019. Descriptive statistics and quantitative ethnobotany were carried out and some ethnobotanical indices were calculated. Results and Discussion: The number of use reports analysed to treat mental disorders in CLA is 2,544 spread over 183 taxa belonging to 64 families, being the most cited the Malvaceae (29.36% of use reports), Lamiaceae (16.71%), Caprifoliaceae (7.94%), Rutaceae (7.47%) and Papaveraceae (6.01%). The most used taxa to treat or alleviate the mental disorders have been Tilia platyphyllos Scop. (24.53%), Valeriana officinalis L. (7.47%), Salvia officinalis L. (5.07%), Sambucus nigra L. (4.28%), and Ruta chalepensis L. (3.89%). The flowers or inflorescences (47.68%), followed by aerial part (23.49%), have been the most used plant parts, and tisane the most commonly used pharmaceutical form (78.03%). The most reported use is as sedative with 40.92%, followed by anticephalalgic (21. 19%) and tranquilizer (20.01%). The informant consensus factor (FIC) was 0.93, and 3.72% was the ethnobotanicity index (EI) value. The information is coincidental with at least one of the comprehensive pharmacological literature sources checked for 73.68% of ethnobotanical uses.

Health Disparities and Comparison of Psychiatric Medication Use before and after the COVID-19 Pandemic Lockdown among General Practitioner Practices in the North East of England.

Psychiatric medications play a vital role in the management of mental health disorders. However, the COVID-19 pandemic and subsequent lockdown limited access to primary care services, leading to an increase in remote assessment and treatment options to maintain social distancing. This study aimed to investigate the impact of the COVID-19 pandemic lockdown on the use of psychiatric medication in primary care settings. We conducted a retrospective claims-based analysis of anonymized monthly aggregate practice-level data on anxiolytics and hypnotics use from 322 general practitioner (GP) practices in the North East of England, where health disparities are known to be higher. Participants were all residents who took anxiolytics and hypnotics from primary care facilities for two financial years, from 2019/20 to 2020/21. The primary outcome was the volume of Anxiolytics and Hypnotics used as the standardized, average daily quantities (ADQs) per 1000 patients. Based on the OpenPrescribing database, a random-effect model was applied to quantify the change in the level and trend of anxiolytics and hypnotics use after the UK national lockdown in March 2020. Practice characteristics extracted from the Fingertips data were assessed for their association with a reduction in medication use following the lockdown. This study in the North East of England found that GP practices in higher health disparate regions had a lower workload than those in less health disparate areas, potentially due to disparities in healthcare utilization and socioeconomic status. Patients in the region reported higher levels of satisfaction with healthcare services compared to the England average, but there were differences between patients living in higher versus less health disparate areas. The study highlights the need for targeted interventions to address health disparities, particularly in higher health disparate areas. The study also found that psychiatric medication use was significantly more common in residents living in higher health disparate areas. Daily anxiolytics and hypnotics use decreased by 14 items per 1000 patients between the financial years 2019/20 and 2020/21. A further nine items per 1000 decreased for higher health disparate areas during the UK national lockdown. People during the COVID-19 lockdown were associated with an increased risk of unmet psychiatric medication demand, especially for higher health disparate areas that had low-socioeconomic status.

Ability and Preparedness of Family Physicians to Recognise and Treat Adolescent Mental Health Disorders in Nigeria and Ghana.

Management of mental health disorders has not been fully integrated into primary care despite been advocated by the World Health Organisation (WHO) and the World Organisation of Family Doctors (WONCA). This study therefore seeks to assess the ability and preparedness of Family Physicians to recognise and treat mental health disorders in adolescents. A descriptive cross-sectional study of 233 randomly selected Physicians Practicing in Family Medicine Clinics in Nigeria and Ghana was conducted using a semi structured self-administered questionnaire that was developed by the researchers and validated with a Cronbach's alpha coefficient of .85. Data analysis was done with the Statistical Package for Social Sciences™ (IBM Corp, Armonk, NY, USA) version 22.0. Respondents had a mean age of 43 ± 8 years, were mostly males 130 (55.79%), practised in Nigeria 168 (72.10%) and have been in practice for over 10 years 149 (63.95%). Majority of respondents 153 (65.67%) received at least one Medical Education sessions in mental health in the preceding 12 months of the study. Out of these, 146 (95.42%) said the sessions enhanced their knowledge of mental health, and 121 (79.08%) said the sessions enhanced their abilities and preparedness to attend to patients with mental disorders. Barriers included stigmatisation 156 (66.95%), poor facilities 136 (58.37%), non-conducive environment 135 (57.94%) and non-cooperation from patients 133 (57.08%). This study showed that a lot of family physicians in Ghana and Nigeria are able and prepared to manage adolescent mental health disorders. They however cited stigmatisation, poor facilities and non-conducive environment as barriers to management of adolescent mental health disorders in primary care. Considering the severity of the disorder, there is a need to increase the training of Family Physicians in the management of adolescent mental health.

NCOG-12. IMPACT OF TUMOR-RELATED SEIZURES ON MENTAL HEALTH DISORDER ORDER IN LOW-GRADE GLIOMA

Abstract INTRODUCTION Majority of LGG patients experience seizures during their disease course, requiring anti-epileptic drugs (AEDs). Frequent seizures negatively impact health-related quality of life (HRQoL). AEDs, moreover, are hypothesized to have mood-modulating effects. As survival for LGG patients has been improving, it is essential that the impact of seizure burden and AEDs on mental health disorders (MHD) be considered. The objective was to measure an association of tumor-related seizures with MHD onset among LGG patients. METHODS This retrospective cohort study queried data from the IBM Watson Health MarketScan® Claims and Encounters Database (2005-2014) to identify LGG patients without prior MHD history who experienced glioma-related seizures. Presence of seizures was determined by anti-epileptic drug fills within one year following LGG diagnosis. Patients with new onset of MHDs were identified using ICD-9 codes for MHDs and psychotropic drug fills in the 12 months post-LGG diagnosis period. Unadjusted odds ratios measured associations between seizures and MHD prevalence. RESULTS 11,458 LGG patients with no history of MHD were included; 1,799 (15.7%) experienced seizures within 12 months of LGG diagnosis. Among them, 494 (27.5%) developed MHD in the post-LGG diagnosis period. Patients who experienced seizures were more likely to develop an MHD compared to patients who did not (OR, 2.19, 95% CI, 1.95–2.47). MHD incidence was significantly associated with female gender (OR, 1.14, 95%, 1.03–1.26) and age range of 35–44 (OR, 1.20, 95%, 1.03–1.39) compared to 18–34. CONCLUSION These findings demonstrated that tumor-related seizures were associated with MHD onset. This highlights the burden of seizures and regular AED use on mental health. The psychosocial and neurological aspects related to seizures and AEDs likely contribute to the multifaceted mental health disorder onset seen among these LGG patients. Proactive counseling, diagnosis, and management of MHDs in LGGs, particularly those with seizures, is warranted.

5.4 Integrating Pharmacogenomic Results Into Clinical Care: Now What?

The role of pharmacogenetic (PGx) guidance in psychopharmacologic management of mental health disorders in children remains unclear for many providers. There continues to be debate in the literature, and a recent pediatric study reflected negative findings when combinatorial PGx findings were applied to clinical care. However, multiple FDA-approved medications have PGx-related dosing guidance. Among the limitations of PGx testing has been the concern that providers are highly influenced by the combinatorial results from commercial labs that drive the selection of medication and at times may cause the practitioner to deviate from evidence-based guidelines.

Association of Low-Grade Glioma Diagnosis and Management Approach with Mental Health Disorders: A MarketScan Analysis 2005-2014.

Simple SummaryLow-grade gliomas (LGGs) comprise 13–16% of glial tumors. As survival for LGG patients has been improving, it is important to consider the effects of diagnosis and treatment on mental health. The aims of this retrospective cohort study were to determine the incidence, prevalence, and risk factors of mental health disorders (MHD) in LGG patients. In our analysis including 20,432 LGG patients, we identified an MHD prevalence of 60.9%. Of those with no history of prior MHD, 16.9% of LGG patients developed a new onset of MHD within 12 months of LGG diagnosis. Risk factors included female gender, ages 35–54, presence of seizures, and first-line surgical treatment. Therefore, proactive surveillance and counseling surrounding MHDs are recommended among LGG patients. Impact of surgery on brain networks affecting mood should also be considered.Low-grade gliomas (LGGs) comprise 13–16% of glial tumors. As survival for LGG patients has been gradually improving, it is essential that the effects of diagnosis and disease progression on mental health be considered. This retrospective cohort study queried the IBM Watson Health MarketScan® Database to describe the incidence and prevalence of mental health disorders (MHDs) among LGG patients and identify associated risk factors. Among the 20,432 LGG patients identified, 12,436 (60.9%) had at least one MHD. Of those who never had a prior MHD, as documented in the claims record, 1915 (16.7%) had their first, newly diagnosed MHD within 12 months after LGG diagnosis. Patients who were female (odds ratio (OR), 1.14, 95% confidence intervals (CI), 1.03–1.26), aged 35–44 (OR, 1.20, 95% CI, 1.03–1.39), and experienced glioma-related seizures (OR, 2.19, 95% CI, 1.95–2.47) were significantly associated with MHD incidence. Patients who underwent resection (OR, 2.58, 95% CI, 2.19–3.04) or biopsy (OR, 2.17, 95% CI, 1.68–2.79) were also more likely to develop a MHD compared to patients who did not undergo a first-line surgical treatment. These data support the need for active surveillance, proactive counseling, and management of MHDs in patients with LGG. Impact of surgery on brain networks affecting mood should also be considered.

Management of Mental Health Disorders in Patients With Human Immunodeficiency Virus

Compared with the general population, people living with human immunodeficiency virus are at a higher risk of developing mental health conditions such as depression, substance use disorders, posttraumatic stress disorder, suicidality, psychosis, and generalized anxiety disorder. These conditions can negatively impact the patient’s treatment options, adherence to treatment, and eventual health outcome. Unfortunately, these conditions often go undetected and the correlation with the disease unrecognized. Primary care providers for people living with human immunodeficiency virus need to screen and manage these mental health disorders for improved prognosis.

A virtual course in perinatal mental health for healthcare professionals.

Screening and treatment of perinatal mental health problems remain inadequate with one of the barrier being non-availability of trained health professionals. Virtual courses have been an important medium to enhance the knowledge and capacity of health professionals. A virtual certificate course in perinatal mental health was developed to train health professionals to identify and treat perinatal mental health disorders. Of the 41 participants, 90.2 % fulfilled the attendance criterion and 75.6 % of them secured the certification. Encouraging feedback (9.54/10) indicated that virtual courses could help enhance competency in health professionals to identify and treat perinatal mental health disorders.

A clinical audit to investigate polypharmacy and interactions in inpatients in an old age psychiatric ward

AimsTo identify any problematic polypharmacy in the patient records of those staying in Cherry Ward, an old age psychiatric unit at Highbury Hospital, Nottingham in the calendar year 2018.BackgroundMulti-morbidity is defined as more than one long-term medical condition in a single individual and is a factor that is closely associated with polypharmacy, the use of multiple medications concurrently. Appropriate and Problematic are the two classifications of polypharmacy outlined by the King's Fund report, the first describing optimised evidenced-based pharmacological management of comorbidities and the latter to label prescribed medications whose use is not in the best interests of the patient. The risk of drug interactions and adverse drug reactions is increased with polypharmacy, and frail elderly patients are particularly at risk of the side-effects of psychotropic medications used in the management of mental health disorders. Guidelines highlight this group as a key party to be identified when searching for at-risk people.MethodThe electronic records of those admitted and discharged from Cherry Ward in 2018 were reviewed in the period spanning January to May 2019, and the first forty-three patients were analysed in Microsoft Excel using criteria based on the King's fund report and the Medscape and BNF (British National Formulary) drug interaction tools. The Medscape drug interaction checker was used for initial screening; the complete medication list for each patient was entered into it and the number of interactions was displayed with advice on severity. If necessary, the individual interactions for each specific medication could also be cross-referenced in the BNF using the extensive lists provided for each drug. These are also graded from mild to severe.ResultOn discharge, 69.7% (thirty patients) met the criteria for being at higher risk of polypharmacy. One patient became at higher risk of polypharmacy during admission, and another two stepped down from meeting the criteria on admission but not on discharge. Thirty-one of the forty-three patients had at least one interaction recorded; 18.6% (eight patients) had at least one potentially severe interaction.ConclusionA substantial proportion of patients in Cherry ward in 2018 were at a higher risk of polypharmacy, reflecting current practice as outlined in the King's Fund report. Problematic polypharmacy is common among older patients hospitalised with psychiatric illness. Recommendations include use of an automated electronic system to investigate and flag up problematic polypharmacy and severe medication interactions.

Psychiatric Evaluation and Management in Pediatric Spinal Cord Injuries: a Review.

To summarize current key recommendations in the evaluation and management of mental health disorders associated with spinal cord injuries (SCI) among pediatric patients, based on a review of recent evidence-based literature and clinical experience. Anticipating potential mental health risks among youth with SCI and implementing early multidisciplinary management improves physical and mental health outcomes. When caregivers of youth with SCI model healthy coping strategies, it promotes healthy coping strategies in patients themselves. Peer mentor programs can be instrumental in patient adjustment, improve mental health, and aid in recovery. Pediatric SCI is particularly impactful on a child's development and individuation. Early involvement of a mental health team while in the hospital can help with the initial adjustment period and address psychiatric concerns that might interfere with recovery. The transition from the hospital to home is a period of vulnerability for individuals with SCI.

Management of Mental Health Disorders, Substance Use Disorders, and Suicide in Adults with Spinal Cord Injury: Clinical Practice Guideline for Healthcare Providers.

Management of Mental Health Disorders, Substance Use Disorders, and Suicide in Adults with Spinal Cord Injury: Clinical Practice Guideline for Healthcare Providers.

Management of Mental Health Disorders, Substance Use Disorders, and Suicide in Adults with Spinal Cord Injury

Management of Mental Health Disorders, Substance Use Disorders, and Suicide in Adults with Spinal Cord Injury