Innovation Management Research Articles

Strategic lead compound design and development utilizing computer-aided drug discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields.

Wheat (Triticum aestivum) is a vital cereal crop and a staple food source worldwide. However, wheat grain productivity has significantly declined as a consequence of infestations by Phalaris minor. Traditional weed control methods have proven inadequate owing to the physiological similarities between P. minor and wheat during early growth stages. Consequently, farmers have turned to herbicides, targeting acetyl-CoA carboxylase (ACCase), acetolactate synthase (ALS) and photosystem II (PSII). Isoproturon targeting PSII was introduced in mid-1970s, to manage P. minor infestations. Despite their effectiveness, the repetitive use of these herbicides has led to the development of herbicide-resistant P. minor biotypes, posing a significant challenge to wheat productivity. To address this issue, there is a pressing need for innovative weed management strategies and the discovery of novel herbicide molecules. The integration of computer-aided drug discovery (CADD) techniques has emerged as a promising approach in herbicide research, that facilitates the identification of herbicide targets and enables the screening of large chemical libraries for potential herbicide-like molecules. By employing techniques such as homology modelling, molecular docking, molecular dynamics simulation and pharmacophore modelling, CADD has become a rapid and cost-effective medium to accelerate the herbicide discovery process significantly. This approach not only reduces the dependency on traditional experimental methods, but also enhances the precision and efficacy of herbicide development. This article underscores the critical role of bioinformatics and CADD in developing next-generation herbicides, offering new hope for sustainable weed management and improved wheat cultivation practices. © 2024 Society of Chemical Industry.

Unpacking innovation in digital multi-sided platform startups: making sense of path creation in generating two distinct types of innovation

Purpose This study aims to investigate the role of effectual logic as the basis of entrepreneurial action in path creation for influencing the performance of open innovation outcomes within the context of digital multi-sided platform (MSP) startups. Design/methodology/approach We utilize the PLS-SEM method with a sample of 70 Indonesian digital MSP startups that have implemented open innovation practices. Findings The empirical findings indicate a path creation between effectual logic and the open innovation process, particularly through the integration of absorptive capacity and crowds or communities management practices. Absorptive capacity development fosters incremental innovation, whereas crowds or communities management practices lead to radical innovation. Originality/value The research findings suggest that, despite limited resources and experience, young entrepreneurs can successfully implement an open innovation strategy for their digital MSP platforms by utilizing effectual logic principles, which capitalize on the external resources provided by digital platform ecosystem members.

Pengaruh Manajemen Pemasaran, Kreativitas, Inovasi, dan Lokasi terhadap Loyalitas Konsumen (Studi Kasus Usaha Mie Aigo di Kamal)

Opening a restaurant business or the trend called a restaurant is currently more popular with entrepreneurs. Moreover, recently types of food such as noodles have been admired by many people, especially noodle lovers. When starting a business, you must pay attention not only to preparing materials and finances, but being ready to take risks is an important thing to overcome existing problems. That way, entrepreneurs have to work harder to gain and maintain consumer loyalty. This research was conducted to determine the influence of marketing management, creativity, innovation and location on consumer loyalty (Case Study of the Aigo Noodle Business in Kamal). The aim of this research is to determine the influence of marketing management, creativity, innovation and location on consumer loyalty (case study of the Aigo noodle business in Kamal) partially and simultaneously. The type of research used was quantitative with a Likert scale and 30 respondents. The sampling Technique in the research used Convenience Sampling. The research results showed that the marketing management variable (X1) had a significant influence on consumer loyalty. This is proven by a value of 0.001 < 0.05 and Tcount of 3.654 > 2.060. So Ho is rejected, and Ha is accepted. The creativity variable (X2) has a negative but significant influence on consumer loyalty. This is proven by a significance value of 0.000 <0.05 and a T value of -6.356 <2.060. So Hoe was rejected and Ha was accepted. The innovation variable (X3) has a negative but significant influence on consumer loyalty. This is proven by a significance value of 0.034<0.05 and a Tcount value of -2.244<2.060. So Hoe was rejected and Ha was accepted. The location variable (X4) has a significant influence on consumer loyalty. This is proven by a significance value of 0.000 <0.05 and a T value of 6.015> 2.060. So Hoe was rejected and Ha was accepted. Testing F, it can be concluded that there is a simultaneous influence between marketing management variables (X1), creativity (X2), innovation (X3), location (X4) on consumer loyalty variables (Y). This is proven by a significant value of 0.000 <0.05 and Fcount of 54.996 > 2.76. This means that there is a simultaneous influence between marketing management variables (X1), creativity (X2), innovation (X3), location (X4) and consumer loyalty variables (Y).

Innovative strategies for characterizing and managing huanglongbing in citrus.

Huanglongbing is a severe citrus disease that causes significant tree and crop losses worldwide. It is caused by three Candidatus liberibacter species and spread by psyllids and infected budwood. Various methods have been used to diagnose and understand HLB, including recent advances in molecular and biochemical assays that explore the pathogen's mode of action and its impact on the host plant. Characterization is essential for developing sustainable HLB management strategies. Nanotechnology, particularly nano sensors and metal nanoparticles, shows potential for precise disease diagnosis and control. Additionally, antibiotics, nanomaterials, and genetic engineering techniques like transgenesis offer promising avenues for mitigating HLB. These diverse approaches, from conventional to cutting-edge, contribute to developing integrated HLB management strategies for sustainable citrus cultivation. The review highlights the significant advancements in conventional and advanced molecular and biochemical characterization of HLB, aiding in early detection and understanding of the infection mechanism. It emphasizes the multidimensional efforts required to characterize disease and devise innovative management strategies. As the citrus industry faces unprecedented challenges, exploring new frontiers in HLB research provides hope for sustainable solutions and a resilient future for global citrus cultivation.

Strategic Innovation in Crisis Management Converting into Opportunity: A Case Study of the Dubai Government

Purpose: The conventional crisis management framework, which is characterized by predetermined protocols and reactive actions, has proven ineffective in the face of the complex circumstances of today. The Dubai Government has acknowledged this and adopted a paradigm shift toward strategic innovation, marking a break from the status quo and a readiness to accept uncertainty as a necessary step toward advancement. The strategic innovation framework used by the Dubai Government's crisis management plan will be thoroughly examined in this research. The purpose of the study is to elucidate the guiding principles that have placed this forward-thinking organization at the forefront of crisis resilience via the prism of this progressive organization. It aims to understand the mechanics of crisis management and to draw general lessons that may be used in other organizational contexts by probing the methodology, technologies, and cultural shifts that support this novel approach (Alketbi, del Rio and Fernández, 2022). Methodology: To encapsulate, this research utilizes a qualitative triangulation approach that focuses on the relationship between strategic innovation and crisis management, specifically examining the Dubai Government. By combining qualitative interviews, quantitative surveys, and content analysis, the study provides a comprehensive view of the topic, enabling a thorough investigation of the research questions and objectives. Findings: Based on prior research and global trends, the main finding is to understand the Dubai Government who has seamlessly merged innovation into its crisis management tactics. The focus is on how the Dubai Government integrates advanced technological tools and fosters a culture where challenges are viewed as opportunities for growth. For instance, the adoption of AI-based predictive analytics in crisis anticipation and response is a testament to this innovative approach. Unique Contribution to Theory, Practice and Policy: The study anticipates that these practices not only enhance crisis management effectiveness but also serve as a model for other organizations globally.

Strategi Pengembangan Desa Wisata dalam Lomba Spot Selfie Kelurahan Jatirejo Kecamatan Gunungpati

The development of tourist villages has become a global trend driven by cultural and environmental preservation, as well as its potential to increase local community income. The purpose of this research is to analyze the development strategy of Jatirejo Village, Gunungpati District, through the Spot Selfie Competition, which leverages the village's potential to attract tourists, especially the younger generation. This competition is not merely a selfie spot contest but also an effective tourism promotion tool that can spark community creativity in creating attractive selfie spots. The results of the study show a positive impact on increasing tourist numbers, local income, and the preservation of culture and the environment. Moreover, this spot selfie competition introduces innovation in the sustainable management of tourist villages. This research is expected to contribute to effective and sustainable tourist village development policies in Indonesia

Numerical analysis of magnetohydrodynamic effects on hybrid nanofluid cooling in high-density servers

This study numerically examines active CPU cooling using hybrid nanofluids in a novel heatsink design. The proposed heatsink is a parallelepiped block filled with Al2O3-CuO/water nanofluid, traversed by four strategically placed cooling tubes. It meticulously investigates the effects of CPU temperature (10³ ≤ Ra ≤ 10⁶) and magnetic field strength (0 ≤ Ha ≤ 100) on overall cooling capacity. With hybrid nanofluids, heat transfer and cooling efficiency are substantially improved, according to comprehensive finite element analysis conducted in COMSOL Multiphysics. The study provides valuable insights for designing high-performance CPU cooling systems, carefully considering nanofluid properties, diverse thermal conditions, and complex magnetic effects. The promising results show that using advanced hybrid nanofluids and an optimized magnetic field can significantly enhance the cooling performance of modern high-powered CPUs. The groundbreaking research highlights the immense potential of combining cutting-edge nanotechnology and magnetohydrodynamics in innovative thermal management solutions. This novel approach could lead to more efficient, compact, and adaptable cooling systems for next-generation electronic devices, effectively addressing the persistent challenge of heat dissipation in high-performance computing environments.

Financing diversified water strategies for megacities: the case of Mexico City and rainwater harvesting

Abstract Megacities are increasingly confronted with water supply challenges, requiring innovative and diversified management strategies to ensure sustainability. This study examines Mexico City’s Cosecha de Lluvia program, a government initiative promoting residential rainwater harvesting (RWH). This case study offers valuable lessons for other megacities facing similar water security issues. The study particularly explores result-based financing (RBF) as a promising strategy to strengthen Mexico City’s RWH sector. Despite its potential, research on RBF for water supply diversification remains limited, especially from the perspective of practitioners. To address this gap, the study employs a systems thinking approach supported by qualitative methods, including a literature review and interviews. Thematic networks analysis revealed that RBF could enhance Cosecha de Lluvia by improving monitoring and results measurement, facilitating information exchange, and increasing transparency—key factors for successful water supply diversification. While these identified benefits do not address all of Cosecha de Lluvia’s challenges and RBF could have implementation challenges, there is a clear opportunity for this financial mechanism to enhance programs like the one studied and have a positive impact on several of its elements. As part of the RBF suitability assessment, three different funding sources were evaluated—public, private, and philanthropic—to determine their effectiveness in overcoming Cosecha de Lluvia’s challenges. The findings suggest that no single source of finance markedly influences the program’s effectiveness alone. Instead, a blended financing approach that integrates all three sources is recommended as a strategy to explore further for implementing RBF in water supply diversification efforts. Overall, the study highlights the necessity of diversifying water supply to build climate resilience in megacities. While programs like Cosecha de Lluvia are crucial, significant room for improvement exists. RBF offers a promising mechanism to enhance such initiatives, and its potential merits further exploration.

SCENOGRAPHY DESIGN IN A DIRECTOR’S ARTISTIC PRACTICE

The paper describes a methodology of designing scenography for a contemporary theatrical performance in the academic process. The systematic approach to artistic visualisation of a performance, modernisation of its structure, selection of scenography functions, style and type of design widen the range of the director’s interaction with the audience as well as contributes to effective management of the creative process from the stage of the artistic concept design through to its implementation. The method of depicting compositional schemes to design action development helps individual types of art interweave with the director’s concept, develop creative thinking and cope with numerous management challenges. Designing diverse parts of staging paves the way to developing students’ skills of comprehending the processes of integration of arts and technologies. The “directing scenographic concept” method contributes to the integration of the director’s and the artist’s professional activities, helps to express a creative idea in a groundbreaking form, and turns into an effective tool of innovative design and management of a theatrical performance.

Promoters as social controls to facilitate knowledge sharing, conflict management and innovation project portfolio performance

Organizational control theory emphasizes aligning members' actions with organizational goals through formal and social controls. In innovation management, formal controls like project management or stage‐gate processes are limited to measurable and standardized areas. For situations that are complex, unpredictable and highly idiosyncratic, social controls need to be applied for alignment. Knowledge sharing and competitive conflicts are two such innovation‐related phenomena that elude formal control and instead need social controls for alignment. In this research, we propose that promoters—individuals who actively support innovation—serve as social control agents. While previous research has shown the positive effect of single promoters on individual innovation project success, we propose a comprehensive implementation of all four promoter roles, and we test their joint effect on the intermediate outcomes of knowledge sharing and competitive conflict management facilitating innovation project portfolio performance. Drawing on cross‐industry data of 125 firms collected from 986 employees, this article provides empirical evidence that comprehensive implementation of all four promoter roles enhances knowledge sharing and reduces competitive conflicts, thereby improving innovation project portfolio performance. The research reframes promoters as social control agents, emphasizing their collective necessity for managing complex organizational issues and contributing to overall project success.

Emerging therapies and innovations in vitiligo management: a comprehensive review.

Vitiligo is a common skin disorder where melanocytes, the cells that produce skin pigment, are destroyed by the immune system, leading to white patches on the skin and mucous membranes. This condition affects 0.4% to 2.0% of the global population, with a higher prevalence in females and often beginning in childhood. In India, about 1% of the population is affected, particularly in northern regions, with a higher incidence in females and links to other autoimmune diseases. This review examines recent progress in understanding vitiligo and its treatment. It focuses on the genetic, autoimmune, and environmental factors involved in the disease and highlights new therapies, such as targeted molecular treatments and advanced repigmentation methods. Current research shows that oxidative stress and genetic predispositions contribute to the autoimmune destruction of melanocytes. Novel drug delivery systems, including liposomes, nanoemulsions, and nanostructured lipid carriers, have improved treatment effectiveness. Clinical trials are exploring new treatments like Ruxolitinib cream and melanocyte transplantation, while teledermatology is becoming useful for managing patients. Vitiligo also poses a significant economic burden due to its impact on patients' quality of life. Continued research is essential to develop better, more accessible treatments and reduce the economic impact of vitiligo.

The Impact of Digitalization and Financial Technologies on the Transformation of Human Capital in the Banking Ecosystem

This article examines the changes in the banking ecosystem under the influence of digitalization and financial technologies (FinTech), with a particular focus on the transformation of human capital. Key technologies such as artificial intelligence, big data, and blockchain, which are reshaping workflows and require new competencies from employees, are discussed. The article analyzes strategic partnerships with FinTech companies, changes in the organizational culture of banks, and the need to develop IT skills and innovation management to enhance competitiveness. Special attention is given to Uzbekistan’s experience in integrating digital technologies and formulating a strategy for human capital development in the context of digital transformation.

Financialization and Innovation Management: A Model of Impacts and Evidence from Case Studies in Brazilian Companies

Financialization and Innovation Management: A Model of Impacts and Evidence from Case Studies in Brazilian Companies

Human Resource Management Innovation Strategy in Realizing Competitive Advantage

Human resource management is the most essential thing in an organization. Because superior human resource management can increase competitiveness, for this reason, management needs to study more deeply the resources that can be relied on to compete in a competitive business environment and place leverage on resources that can place the company in a competitive position in the long term. Therefore, human resource management innovation strategies have many managerial implications for business policymakers. The research used a qualitative approach with literature methods (library study), which are appropriate to the current problems. Namely the importance of human resource management strategies to realize superior competitiveness. The results of this research show that human resource management is the heart of corporate or organizational governance. Management strategies and innovations are needed to improve superior and competitive human resources. Steps or forms of innovation strategy for Human Resources (HR): Continuous training in stages and stages, Mastery of technology and digitalization, More active marketing, Forming a solid team, Establishing more comprehensive relationships, Transparency, Committed, Competent, Flexible, and Innovative integrated as a competitive quality.

Bifenthrin at Sublethal Concentrations Suppresses Mating and Laying of Female Conogethes punctiferalis by Regulating Sex Pheromone Biosynthesis and JH Signals.

Conogethes punctiferalis, a polyphagous pest in Asia, infests various crops, causing severe economic losses. Its larvae feed inside plants, making management challenging, with conventional insecticides. This study examines sublethal bifenthrin effects on the reproductive capabilities of adult females. Findings show sublethal bifenthrin concentrations (LC1, LC10, LC20, and LC30) significantly reduce sex pheromone production and mating success in a dose-dependent manner. Furthermore, these sublethal exposures influence the expression of pheromone biosynthesis activating neuropeptide and key juvenile hormone signaling genes, including methoprene-tolerant and Krüppel-homologue 1. Enzyme activity assays and metabolite measurements indicated that sublethal bifenthrin exposure decreases trehalose and pyruvic acid levels, suppressing the enzyme activities required for sex pheromone biosynthesis. Additionally, bifenthrin exposure delays ovarian development, reduces ovary size, and decreases egg production and hatchability. These results suggest bifenthrin's potential in attract-and-kill strategies by disrupting essential pathways for pest control, offering insights for improved insecticide use and innovative pest management for C. punctiferalis.

Bonding versus bridging: disentangling effects of CEO social capital on firm exploratory innovation

CEOs and the influence of their social networks have been considered as important drivers for firm innovation. Yet, both theories and empirical evidence are lacking. To advance this stream of research, our paper fills the gap by exploring how bonding and bridging social capital influence exploratory innovation in firms. Through an examination of executive social ties and patent‐based technology indicators, our findings reveal nuanced relationships: Excessive bonding social capital exponentially hampers exploratory innovation due to information overload, while bridging social capital enhances exploratory innovation and mitigates over‐bonding effects (inverted U‐shape). We test our hypotheses with a sample of 7,540 firm‐year observations of public U.S. firms from 2000 to 2014. Our study not only contributes to research on strategic leadership, social capital, interfirm networks, and technological innovation but also offers important managerial implications. It suggests that CEOs and R&D directors foster balanced social networks in their pursuit of enhanced innovation management.

Pinewood nematode induced changes in the assembly process of gallery microbiomes benefit its vector beetle's development.

Microbiomes play crucial roles in insect adaptation, especially under stress such as pathogen invasion. Yet, how beneficial microbiomes assemble remains unclear. The wood-boring beetle Monochamus alternatus, a major pest and vector of the pine wilt disease (PWD) nematode, offers a unique model. We conducted controlled experiments using amplicon sequencing (16S rRNA and ITS) within galleries where beetles and microbes interact. PWD significantly altered bacterial and fungal communities, suggesting distinct assembly processes. Deterministic factors like priority effects, host selection, and microbial interactions shaped microbiome composition, distinguishing healthy from PWN-infected galleries. Actinobacteria, Firmicutes, and Ophiostomataceae emerged as potentially beneficial, aiding beetle's development and pathogen resistance. This study unveils how nematode-induced changes in gallery microbiomes influence beetle's development, shedding light on microbiome assembly amid insect-pathogen interactions. Insights gleaned enhance understanding of PWD spread and suggest novel management strategies via microbiome manipulation.IMPORTANCEThis study explores the assembly process of gallery microbiomes associated with a wood-boring beetles, Monochamus alternatus, a vector of the pine wilt disease (PWD). By conducting controlled comparison experiments and employing amplicon approaches, the study reveals significant changes in taxonomic composition and functional adaptation of bacterial and fungal communities induced by PWD. It identifies deterministic processes, including priority effects, host selection, and microbial interactions, as major drivers in microbiome assembly. Additionally, the study highlights the presence of potentially beneficial microbes such as Actinobacteria, Firmicutes, and Ophiostomataceae, which could enhance beetle development and resistance to pathogens. These findings shed light on the intricate interplay among insects, microbiomes, and pathogens, contributing to a deeper understanding of PWD prevalence and suggesting innovative management strategies through microbiome manipulation.

The role of strategic communication and sensemaking in implementing management innovation

PurposeThis study explores the dynamics of implementing management innovation, focusing on a case of innovation in human resource management within a large Japanese firm. It aims to understand how innovators perceive and react to employees’ evolving responses to management innovation and how these perceptions and reactions influence innovation implementation.Design/methodology/approachThe study employed a single-case study design because it was suitable for exploring complex phenomena within their real-life context. It involved an in-depth analysis of a firm undergoing management innovation through participant observation, interviews and analysis of company documents.FindingsThe study identified a multi-phase process of management innovation at the research site, characterized by initial resistance followed by gradual acceptance of the innovation. Innovators’ strategies to manage and respond to employee feedback and adaptation of the innovation process were crucial in the eventual acceptance of management innovations. Despite achieving a degree of acceptance, cultural and structural challenges persisted, highlighting the complex interplay between innovation, organizational culture and employee responses.Originality/valueThis research contributes to the management innovation literature by illuminating the intricate dynamics of implementing management innovation. It extends existing theories of innovation implementation by demonstrating the significance of managing recipient perceptions through strategic communication and the importance of cultural and contextual sensitivities in management innovation.

Sustainable Energy Application of Pyrolytic Oils from Plastic Waste in Gas Turbine Engines: Performance, Environmental, and Economic Analysis

The rapid accumulation of polymer waste presents a significant environmental challenge, necessitating innovative waste management and resource recovery strategies. This study investigates the potential of chemical recycling via pyrolysis of plastic waste, specifically polystyrene (PS) and polypropylene (PP), to produce high-quality pyrolytic oils (WPPOs) for use as alternative fuels. The physicochemical properties of these oils were analyzed, and their performance in a gas turbine engine was evaluated. The results show that WPPOs increase NOx emissions by 61% for PSO and 26% for PPO, while CO emissions rise by 25% for PSO. Exhaust gas temperatures increase by 12.2% for PSO and 8.7% for PPO. Thrust-specific fuel consumption (TSFC) decreases by 13.8% for PPO, with negligible changes for PSO. The environmental-economic analysis indicates that using WPPO results in a 68.2% increase in environmental impact for PS100 and 64% for PP100, with energy emission indexes rising by 101% for PS100 and 57.8% for PP100, compared to JET A. Although WPPO reduces fuel costs by 15%, it significantly elevates emissions of CO2, CO, and NOx. This research advances the understanding of integrating waste plastic pyrolysis into energy systems, promoting a circular economy while balancing environmental challenges.

Decision-making strategies for organizational processes

This research aims to explore decision-making strategies in organizational processes and their relevance in today's business environment, using a comprehensive methodology based on a review of the scientific literature. Different approaches and methodologies used for decision making are presented, such as data-driven decision making, multi-criteria decision making, collaborative decision making and decision making based on artificial intelligence and machine learning. In addition, recent applications of these strategies in various organizational contexts, such as manufacturing, logistics and supply chain, project management, and product innovation and development, are discussed.