Malignant neoplasms (MNO) are a significant social, social and medical problem of modern society. Cancer is the leading cause of death in the world, from which about 10 million people died in 2020. In this regard, the identification of the main factors contributing to oncogenesis is the most urgent task of modern clinical medicine. Tumor formations of malignant genesis are polyetiological. It has not been finally established which of the factors is of paramount importance, but it has been revealed that various psychosocial processes are triggers. Among them: social status, working conditions, life events (depression, hopelessness, loss of a loved one, etc.). A detailed study of the relationship between psychosocial factors and environmental factors in the development, progression and mortality from certain types of cancer is important in understanding the main mechanisms of prevention of this pathology. The analysis of the results obtained can be taken into account in the development of personalized measures to prevent the development of cancer in a particular individual.