Simple SummaryProstate cancer is a very common neoplasm in men, with surgery being a valuable tool for its successful management. The prostate gland lies deep in the male pelvis with several sheets of fibrous membranes surrounding it along anterior, lateral, and posterior surfaces. These membranes are called fasciae. Arteries, veins, and nerve fibers that are important for erectile function and continence can be found within these fasciae. An important fascia covering the posterior surface of the prostate and separating it from the rectum is Denonvilliers’ fascia. This structure is important for the confinement of cancer within the prostate and for completing an operation without damaging the nerves responsible for erectile function and continence while also removing all neoplastic tissue. This review covers the anatomical aspects of this structure, along with providing some clinical insight on how to use this knowledge to improve clinical outcomes.The fascial structure around the prostate has been a controversial issue for several decades, but its role in radical prostatectomy is crucial to achieving successful nerve-sparing surgery. One of the fasciae surrounding the prostate is Denonvilliers’ fascia, forming its posterior border with the rectum and enclosing along its layers several fibers of the neurovascular bundle. This review focuses on embryological and anatomical points of Denonvilliers’ fascia, aiming to provide a summary for the operating general surgeons and urologists of this area.
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