Male Partners Of Infertile Couples Research Articles

Effect of Obesity on Hormonal Profile and Semen Parameters of Male Partners of Infertile Couples in Kwara State Nigeria

Background : Infertility is a global and a public health concern in many parts of subSaharan Africa and obesity is gradually becoming an epidemic disease that is rapidly spreading among Africans. Male obesity has been associated with increased incidence of low sperm concentration and progressively low motile sperm count. Methods: The study was a multicenter prospective comparative analytical study conducted at the University of Ilorin Teaching Hospital (UITH), Anchor Medical Centre, Royal Medical Centre, Surulere Medical Centre and Mid-land Fertility Centre all in Ilorin, Kwara State, Nigeria over a period of six months (February to July 2011). Our aim was to identify the effect of male obesity on measures of reproductive potentials among male partners of infertile couples. Serum levels of testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and estrogen of 42 obese and 42 non obese male partners of infertile couples were assayed in addition to seminal fluid analysis. Results: There was a statistically significant association between obesity, class of obesity with sperm count and sperm motility (All P 0.05). Conclusion: This study has demonstrated an inverse but significant relationship between male obesity and semen parameters (sperm count and motility), serum

Seminogram in Male Partners of Infertile Couples

<p><strong>Background</strong>: Infertility is defined as failure to conceive within one or more years of regular unprotected coitus. The infertility state is dependent on the female factor as well as masculine factor; an altered masculine factor is designated when any cause or causes of infertility reside in the male. The masculine factor as a cause of infertility is present in 40-50 % of cases hence the importance of an integral evaluation of the male alterations and its fertility.</p><p><strong>Objectives</strong>: The present study aims to assess the seminal patterns of male partners of 100 infertile couples for various parameters and their possible contribution to infertility.</p><p><strong>Material and Methods</strong>: The present study was conducted on male partners of 100 infertile couples who were referred by Gynecology and Obstetric department to Pathology Department, Government Medical College, Patiala for semen examination. The semen was collected by masturbation in all cases in a clean dry detergent free container. After liquefaction and mixing, basic analysis was done which includes volume, viscosity, pH, spermatozoal concentration, motility and morphology. Data was evaluated by means of chi-square test.</p><p><strong>Results</strong>: Of 100 seminogram, 43% showed alterations in the seminal indexes; with asthenospermia in 39.5%, Oligoasthenospermia in 30.2%, Oligospermia in 16.2%, and Azoospermia in 13.9%.</p><p><strong>Conclusion</strong>: Male factors were mostly responsible as a cause of infertility. Asthenospermia was the most common type of semen defect present in these infertile males. Most of the males with semen defect were of age group >30yrs. Incidence of semen defect among males increased with duration of infertility.</p>

Bacterial Isolates and Semen Analysis of Male Partners of Infertile Couples.

BACKGROUND: Seminal tract infections alter the semen quality and affect the sperm parameters of men with varying degree of effect to male fertility. OBJECTIVES: This study was carried out to investigate the presence of infectious agents other than sexually transmitted infections in semen and their relation to semen parameters. METHODS: Five hundred and eighty-seven semen samples of males investigated for infertility were analyzed, inoculated on sterile culture media, and incubated for 24hrs at 37 o C. The isolates were identified by standard biochemical tests and their antimicrobial susceptibility determined. RESULTS: Fifty-four percent of the samples had normal sperm concentration, 41.1% had oligospermia, and 4.9% had azoospermia. About 64.7% had normal viscous consistency, 23.0% were high viscous, and 12.3% low viscous. Also, 19.4% had highly motile permatozoa, 51.5% moderately, 27.6% poorly and 1.6% entirely non-motile spermatozoa. About 55.9% of the samples were infected with different nonspecific pathogens. CONCLUSSION: 55.9% of the semen samples were infected and this significantly affected the semen parameters. It is necessary to investigate male partners of infertile couples for infections and appropriate treatment initiated.

Pattern of Semen Fluid Abnormalities in Male Partners of Infertile Couples in Southeastern, Nigeria

The incidence of male infertility is increasing in our environment. There is a need to evaluate the pattern of abnormality with a view to recommending appropriate interventions. We aimed to to analyze the seminal fluid parameters of the male partners of the infertile couples managed in the hospital over a 12 month period and to identify the pattern of abnormalities. A retrospective study of all the semen samples of male partners of infertile couples submitted for analysis to the microbiology laboratory of Nnamdi Azikiwe University Teaching Hospital, Nnewi Nigeria between 1st January 2006 and 31st December 2006 The reports of the semen fluid analysis were retrieved from the records department and supplemented with the laboratory register. Out of the 348 semen sample reports evaluated, 237 (68.0%) had semen fluid abnormalities. 104 (30.0%) had single factor abnormalities while 133 (38.0%) had combined factor anomalies. Asthenozoospermia 58 (16.7%) was the main single abnormality, while Astheno-oligozoospermia 51 (14.7%) and Astheno-oligoteratozoospermia (13.2%) were the major combined factor abnormalities detected. Very few 5 (1.4%) of the patients had azospermia. The study showed a high rate of semen fluid abnormalities among the male partners of infertile women in our environment. The high preponderance of poor motility emphasizes the need to include men in programmes aimed at reducing sexually transmitted infections in Nigeria.

Revisit Of Current Patterns Of Semen Quality Among Male Partners Of Infertile Couples Seen At The Jos Unviversity Teaching Hospital

Background: Infertility is a worldwide problem and the contribution of the male partner is significant. In general one out of seven couples will have problem with fertility.Materials and Methods: This was a 5 year retrospective study, in which the results of seminal fliud analysis of male partners of infertile couples were retrieved from the Andrology Research Laboratory of the Department of Obstetrics and Gynaecology, Jos University Teaching Hospital/University of Jos between 1999 and 2004. The results were critically analysed for critical days of abstinence, volume of semen collected, methods of collection of semen, the quality of the semen and the presence of pus cells greater than 5 per high power field.Results: The results showed that majority of the patients (68.2%) abstained from intercourse for 3-4 days, while17.4% abstained for greater than 7days. About 61% of the patients produced semen by coitus interruptus while, 34.3% obtained their samples by masturbation. Majority of the patients (70.1%) produced semen volume of greater than 2mls, while 29.9% produced semen of less than 2mls. Of the total number, 34.7% were normozoospermia while, 65.3% had one semen abnomality or the other. Pus cells were present in a total of 6.6%.Conclusion: Majority of the men followed the standard protocol for semen production and collection.However, semen abnormalities were high among partners of infertile couples, which may explain the infertility in those couples. However, in males with normal semen qualities, other factors may be responsible for the infertility.Keywords: Semen abnormalities, Infertility, semen abnormalities, Jos UniversityTeaching Hospital.

Semen Quality in Male Partners of Infertile Couples in Lagos Nigeria

Semen Quality in Male Partners of Infertile Couples in Lagos Nigeria

Classification of the semen of the male partners of infertile Nigerian couples.

Semen samples from 500 Nigerian male partners of infertile couples were classified according to their sperm counts and progressive motility. 74.15% of these men were normozoospermic while 16.19, 5.57 and 4.09% were azoospermic, necrozoospermic and asthenozoospermic, respectively. The degree of oligozoospermia was mild (35.88%), severe (23.22%) or very severe (40.90%). The classifications of two consecutive samples per patient collected two weeks apart were highly correlated. Results show that in over 70% of these infertile couples, infertility was due to a female factor, the absence of which therefore has to be established before semen analysis. Some socioeconomic factors in infertility were also implied.

Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in Semen and First Void Urine Specimens of Asymptomatic Male Partners of Infertile Couples

The purpose of this study was threefold: to compare semen and first void urine (FVU) specimens from asymptomatic infertile men for the detection of Chlamydia trachomatis, genital ureaplasma, and genital mycoplasma infections using in-house inhibitor-controlled polymerase chain reaction (PCR)-microtiter plate hybridization assay; to determine the prevalence of those organisms in infertile men in Tunisia; and to study the relationship between these bacteria and male infertility. Paired urine and semen specimens from 104 patients were examined by in-house PCR for the presence of DNA of Chlamydia trachomatis, genital ureaplasmas (Ureaplasma urealyticum and Ureaplasma parvum) and genital mycoplasmas (Mycoplasma hominis and Mycoplasma genitalium). Semen analysis was assessed according to the guidelines of the World Health Organization. Nominal scale variables, the Mann-Whitney test, and the Kruskal-Wallis nonparametric analysis of variance test were used for statistical analysis. There was a very high concordance (>95%) and a very good agreement (kappa > 0.9) between the detection of Chlamydia trachomatis, genital ureaplasmas, and Mycoplasma hominis in semen and corresponding FVU specimens. Our findings also show a high concordance (81.1%) and a good agreement (kappa = 0.79) between the detection of Mycoplasma genitalium in both specimens. C trachomatis, genital mycoplasmas, and genital ureaplasmas were found to be widespread among infertile male patients in Tunisia, as shown by their respective prevalences of 43.3%, 18.3%, and 14.4%. The mean values of seminal volume, sperm concentration, sperm viability, sperm motility, sperm morphology, and leukocyte count were not significantly related either to the detection of C trachomatis DNA or to that of genital ureaplasma or mycoplasma DNA in semen specimens. Using our in-house PCR, both semen and FVU were found to be sensitive diagnostic specimens for the detection of C trachomatis, ureaplasmas, and mycoplasmas. The FVU, a less invasive and self-collected specimen, can serve as a marker for the presence of these organisms in the genital tract and can be used as a reliable way of detecting asymptomatic carriers of infection.

Trace Elements and Sperm Parameters in Semen of Male Partners of Infertile Couples

The relationships between element concentrations and sperm parameters in semen samples were investigated. Semen samples (n = 113) were donated voluntarily by male partners of infertile couples. The concentrations of fourteen elements (Na, K, P, Ca, Zn, Mg, Fe, Cu, Se, Mn, Sn, Co, Ni, and Cd) in semen were determined by atomic absorption spectrometry, fluorometry, or colorimetry. Element concentrations in seminal plasma and in sperm were also measured. Element concentrations in semen were in the order Na > P, K > Ca > Zn > Mg > > Fe> Cu, Se > Mn > Sn, Ni, Co, Cd. When the samples were divided into two groups in terms of sperm concentration and number, the Se concentration in semen with normal parameter values (sperm concentration > or = 20 x 10(6) and sperm number > or = 40 x 10(6)), 99.4 +/- 37.4 ng/ml, was higher than that in semen with abnormal parameter values (sperm concentration < or = 20 x 10(6) and/or sperm number < or = 40 x 10(6)), 72.1 +/- 33.9 ng/ml (p < 0.001). A clearer positive correlation between the Se concentration and the sperm concentration was observed in the sperm portion (r = 0.853, p < 0.001) than in semen (r = 0.512, p < 0.001) and seminal plasma (r = 0.292, p = 0.003). Statistically significant correlations were also observed between the concentration of Se, P, Zn, Cu, Fe, or Mn in semen, the sperm portion or seminal plasma and the sperm concentration, semen volume or abnormal morphology, although correlation coefficients were small. Among biologically essential elements in semen of infertile males, Se was a good indicator of sperm concentration; however, other trace elements did not indicate clear relationships between their concentrations and sperm parameters.