Students dropped-out are on the increase across the nation’s universities and several factors have led to this dropped-out of school. This dropped-out of school of students have psychologically affects parents. The aim of the study is to ascertain the Psychological Effects Arising from Male Students Dropped-Out of School On Parents in South-South, Nigeria. The participants were male parents. A sample size of 480 participants were used for the study and the participants age were within 40 to 76 years. The study lasted for three months. Each participant was given one questionnaire to filled and submit after instructions by the research assistants. The findings showed that 79.17% of the participants were within 50-70 years of age. 62.50% of the participants had tertiary education and 62.50% were married, 16.67% were single and 20.83% were divorced. 62.50% were civil servants. The findings of the students course of study shows that 14.58% studied MBBS, 16.66% law, 10.42% engineering, 8.33% accounting while 50.00% studied other disciplines. 62.50% of the participant’s children were first born, 20.83% second borne while 16.67% were last born and 83.20% of the students were dropped-out. 95.83% of the participants were not happy and 50.00% had increase in BP. The psychological effects on parents revealed that 18.75% had depression, 6.25% had anxiety, 8.33% were uninterested in life, 14.58% had difficulty in sleeping, 8.33% faced isolation, 4.17% were shamed, while 39.58% felt hopeless.