Major Work Research Articles

Palliative care and end stage liver disease: A survey study comparing perspectives of hepatology and palliative care physicians and clinical scenarios that could require palliative care intervention

Background and aimsThe prevalence and mortality of chronic liver disease has risen significantly. In end stage liver disease (ESLD) the survival of patients is approximately 2 years. Despite the poor prognosis and high symptom burden of these patients, integration of palliative care is reduced. We aim to analyze the agreement between palliative care and hepatology physicians of clinical scenarios that could require palliative care intervention. MethodsA cross-sectional study was conducted. Palliative care and hepatology physicians were surveyed. Using a five-point Likert scale, their perceptions of palliative care in ESLD were rated. Their agreement in clinical scenarios that could require palliative care intervention were evaluated. Analyses were conducted to assess any differences by primary role (hepatology vs. palliative care) and length of practice (<10 years vs. 10 years). ResultsA total of 123 responses were obtained: 52% from palliative care and 48% from hepatology. The majority (66.7%) work in the field for up to ten years. There was a great consensus in 4 of the 8 clinical scenarios. In scenarios with less consensus, the area of activity and length of practice influence the reliance of physicians on palliative care. Involvement of palliative care in ESLD was considered “rare” by 30% and 61% consider difficult to predict the prognosis. More than 90% support medical training in both areas of activity. ConclusionThe current involvement of palliative care is considered low, but there are clinical conditions that reveal a clear consensus and there's a unanimous view of the relevance of training.

Reading Wollstonecraft after Godwin’s Memoirs: Wollstonecraft in Circulating, Subscription, and Private Libraries, 1799–1842

ABSTRACT Following Mary Wollstonecraft’s death in 1798, her grieving husband William Godwin made public many of the details of Wollstonecraft’s highly unconventional life. The ensuing backlash seemed to ensure that Wollstonecraft’s major works ceased to be reprinted for a period of roughly forty years. This article contributes to efforts to revise narratives of Wollstonecraft’s early nineteenth century reception by asking how and where readers, in the absence of new editions, might have accessed the books themselves. A survey of 41 circulating and subscription library catalogues dated between 1799 and 1842 reveals that, despite scholarly assumptions otherwise, Wollstonecraft’s works remained widely available. Even when books left the library, they did not necessarily disappear, as a copy of Wollstonecraft’s Vindication of the Rights of Woman that moved from a circulating library into a private collection attests. Placing the information in these catalogues in conversation with what can be gleaned from this copy of the work, this article argues that the durability of the hand-press book complicates the narrative of Wollstonecraft’s posthumous reputation.

Fiction by Danil Makeev

Danil Makeev was the first in Yakut literature to turn to the fate of war prisoners, the most tragic side of the World War II theme. The story “The Traitor” reveals the story of Yakut soldier Tarabukin, who went through a penal company and managed to maintain his honor and dignity. The even more acutely tragic fate of a man who suffered mortal trials and monstrous humiliations of captivity is revealed in the story “The Destiny of Fate.” Compared to the story “The Traitor,” the author deepened in it the psychological side of the state of the individual, who many times found himself on the brink of death. The story has a complex composition and is structured like the memoirs of a World War II veteran who, in his declining years, recalls the episodes of the environment, the joy of liberation and the vicissitudes of post-war life with the stigma of a person who was in German captivity. In another story, “Brothers,” Makeev tells about the military “odyssey” of three siblings who returned safely from the front. As for the writer’s stories, what is striking is the variety of intra-genre types in his short prose, skillful plot construction based on the principle of testing heroes, the use of traditions of foreign and Russian literature in creating characters, and a rich arsenal of visual and expressive means. In general, Makeev’s talentedly written novels and short stories give reason to believe that he can create major epic works on the theme of the Great Patriotic War, which in the light of recent events has gained new relevance

SPIRITUALITY AND SUSTAINABILITY: A BIBLIOMETRIC REVIEW

Amidst the global stress escalation triggered by the COVID-19 pandemic, there has been a noticeable surge in people turning to spirituality. Recognizing the growing importance of spirituality in contemporary society, this study investigates the relationship between spirituality and sustainability through a bibliometric analysis, utilizing the SCOPUS database. The main objective of the study is to holistically map and evaluate the direction of the area by identifying prominent themes, patterns, and major works, which in turn will be used as the guiding principles for future research. The analysis of 384 documents reveals a substantial upward trend in publications between 1993 and 2023. Predominantly, studies on spirituality and sustainability originate from the United States of America, India, and Australia. Through the evaluation of bibliometric data, this research identifies leading authors, publications, journals, and institutions in the field. Additionally, keyword co-occurrence analysis, topic modeling, and content analysis unveil the theoretical foundations and emerging patterns, offering valuable insights for future research directions. The study showcases diverse themes in spirituality and sustainability, providing implications for both academics and organizations. Furthermore, it sheds light on areas where research is lagging in the current landscape.

Compound eyes of Camponotus compressus (Fabricius, 1798) (Hymenoptera, Formicidae) reflects caste specific organisation and adaptation

Caste polymorphs of the ant Camponotus compressus (Fabricius, 1798) are distinct by their morphology and life styles; the two distinct castes are largely nocturnal and rely on their visual sensory system to interpret their temporal niches. The compound eyes of the castes were explored through Light and Scanning Electron Microscopy (SEM) in order to delineate cast specific organisation and adaptations of the compound eye. The findings reveal that major workers of C. compressus possess a more sophisticated visual system in terms of its morphological features along with optical properties that enhances a better vision, which includes a greater number of ommatidia and high ommatidial density, a higher ommatidial diameter, low inter ommatidial angle and a more efficient pupillary mechanism to counter conditions where ambient light levels are high. This underlines the dependence of scouts (major workers) on visual system and the foragers on olfactory system in the species.

Pengaruh Kecukupan Pakan Terhadap Produksi Susu dan Kualitas Susu Kambing Di Kecamatan Turi Kabupaten Sleman Yogyakarta

This research aims to determined the effect of feed adequacy on the production and quality of dairy goat milk in Turi District. This research was carried out in the field and laboratory from 01 to 24 October 2023. A total of 98 dairy goat breeders were selected as respondents with the criteria of having at least 1 year of farming experience and having at least 2 animals. From each goat they raise, milk samples are taken to test the quality in the laboratory. The data obtained were analyzed descriptively and by multiple linear regression analysis. The results showed that the average age of farmers is 44 years, with an education level of 86% high school graduates, the number of family dependents of 4-5 people is 67%, the majority work as farmers 52% (69% ≤10 years and 31% ≥11 years). Livestock ownership status is 100% privately owned with an average ownership of 2-5 heads. The average body weight of dairy goats was 40.13 ± 6.91 kg, with milk production of 2.21 ± 0.51 liters/day. Furthermore, the milk quality variable shows that the average specific gravity and non-fat solids are 1.055 ± 0.08 and 8.42 ± 0.43. Feed adequacy (Dry Matter) is 1.43 and Crude Protein adequacy is 7.44. Milk production was significantly (p&lt;0.05) 52.6% influenced by the level of feed adequacy with the regression equation Y = -1.513 + 0.033XI + 0.495X2. Meanwhile, milk density was 48.5% influenced by the level of feed adequacy (p&gt;0.05) with the regression equation Y = 1.043 + 0.073XI - 0.013X2. Likewise, the lean solitaire variable which was not significant (p&gt;0.05) was influenced by the level of feed adequacy (0.75%) with the regression equation Y = 6.874 + 0.155XI + 0.183X2. It was concluded that the adequacy of feed for dairy goats in Turi District for production was sufficient and for milk quality it was in accordance with the 2011 SNI.

The Good Shepherd. On Endre Bálint’s late photomontages

In this paper I analyse the photomontages of Endre Bálint (1914–1986) in the context of the cultural politics of the Iron Curtain period in Eastern Europe and Hungary. First, the study takes a diachronic, historical approach to photomontage as a creative method that maintained continuity between the avant-garde generations of artists, a way of thinking and a creative process accordingly, cultivated in the circles of persecuted, banned or silenced artists experimenting during the decades from the 1920s to 1970s. Second, by placing Endre Bálint’s late photomontages (made after his 1963 return from his “exodus” to Paris) in the context of contemporary artistic phenomena (e.g. Brecht’s photobook, Jean-Luc Godard’s work, David Hockney’s montages or bricoleur punk artists), I argue that, in contrast to the generally held view, they are not the withering signs of renunciation, but rather a way out of renunciation, that is, a solution. “We breathe in fragments,” Bálint wrote, and the pictorial form to fittingly reflect a fragmented way of existence (together with the psychological burdens, shadows of the past, and the social and cultural-political determinations) was the montage-technique that had flourished from the 1920s, and whose Eastern European, distinctively Hungarian variant found its guardian, its good shepherd in Bálint, in his creative practice. Bálint’s late photomontages also deserve attention from the point of view of a silent narrative of art history, which does not focus on middle-aged artists’ major works, but on the profuse production by the old masters, the masters of sprezzatura, which is characterised by an aesthetic lightness, a kind of aesthetic liberation and swiftness, and the ability to allow memories a free influx into the creative work. One of the conclusions of this study is that Hungarian photomontage, and especially the late work of Endre Bálint, can be instructively read in conjunction with the equally restrained psychoanalytic literature of the period, in which the splitting of Self as a traumatic consequence of shocking events and also a means to survive those events is a key concept. A critically productive artistic construction that is based on fragments can be seen and read as the visual counterpart of a psychological notion of Self-splitting.

SZABÓ DEZSŐ TÖRTÉNÉSZPROFESSZOR PÁLYAKÉPE

Dezső Szabó was professor of history at the University of Debrecen for 35 years from 1924 to 1959. He graduated from the University of Budapest with a degree in History and Latin. It was at the instigation of his patron, Henrik Marczali, that he began his research on the Hungarian assemblies of the pre-Mohács period. He also wrote his doctoral dissertation on this topic. Thanks to his excellent academic achievements, he graduated from the university with a royal gold ring of honour (sub auspiciis regis). He taught for many years in secondary schools and in 1912 became a privatdocent at the Budapest University of Science. In February 1924, Governor Miklós Horthy appointed him full professor of medieval and modern (universal) history at the University of Debrecen. At that time, his research was already focused on the Urbarium of Maria Theresa. In 1931 he was elected a corresponding member of the Hungarian Academy of Sciences. He published relatively little and concentrated his activities on secondary school teacher training. He was the dean of the Faculty of Humanities for four academic years. He made an invaluable contribution to the reorganisation of university education in 1944. Despite this, he was repeatedly persecuted under the new regime and was only able to retain his chair thanks to the intervention of his influential students. He retired at the age of 77. The second and third volumes of his work, A magyarországi úrbérrendezés története Mária Terézia korában, which is considered the major work of his life, are still awaiting publication.

Analisis Pemberdayaan Ekonomi Masyarakat Pesisir di Desa Perlis Kecamatan Brandan Barat Kabupaten Langkat

Empowerment is a process of being empowered, having the strength, ability and energy to master something. As a process, empowerment is the first step for people who are powerless to become empowered where people can have strength, ability and master something that can empower their lives, both personally, in their families and in society. Empowerment of coastal communities is expected to be more empowering and improve welfare. In order to improve the community's economy and improve the Human Resources (HR) of fishing communities, of course empowerment programs must exist and be implemented to reach the fishing communities. This research aims to analyze the economic empowerment of coastal communities in Perlis Village, West Brandan District, Langkat Regency with an Enabling, Empowering and Protecting approach. The research method used is qualitative. The results of this research are that Perlis Village, with the majority working as fishermen, has potential, namely processed products from the sea in the form of sea salt, shrimp paste (belacan), and salted fish. The proceeds from sales of these products can help society improve welfare. Furthermore, fishermen who used to work in the sea looking for fish now concentrate on cultivating mud crabs and overseeing ecotourism, although there is still mangrove tourism in the area. These potentials still need to continue to be developed with the empowerment program implemented by the Perlis Village government. Regional government has four roles in community empowerment. First, the role of government regulators is to set rules to balance development implementation. Second, the government functions as a dynamist by encouraging the participation of various parties when the development process stops (encouraging and maintaining the dynamics of regional development). Third, the government functions as a facilitator by creating conducive conditions for the implementation of development (bridging the interests of various parties in optimizing regional development). Fourth, the government functions as a catalyst by encouraging the participation of various parties when the development process is stagnant.

TREATMENT OF INDUSTRIAL WASTEWATER BY USING ECO-FRIENDLY TECHNIQUE

The textile industry is one of the major industries and work as the backbone of economy of Pakistan. It employs thousands of people without any education. It plays important role in the economy of every country around the world. The textile industry has high importance when it comes to the environment because it consumes many environmental resources such as water. Also, it produces a large amount of wastewater which is then discharged into the environment and causes environmental pollution. In this study, Ocimum basilicum L. (sweet basil seeds) and Tamarindus indica seeds have been evaluated as an active natural coagulant for the removal of pollutants from textile wastewater. The change in pH, Dissolved Oxygen, Electrical conductivity, TDS, COD, and heavy metals/pollutants were analyzed. Also, the dye concentration was found to be the most important parameter affecting color removal. Pollutant removal efficiency was obtained by using a low number of coagulants. The mucilage of O. basilicum and the powder of T. indica seeds were found to be highly effective in treating textile wastewater as a sole coagulant. The results show that these coagulants help to reduce heavy metals from 0.16 ppm to 0.02 ppm. Utilization of these natural coagulants was found to be suitable, easier, cost-effective, and environment friendly for textile waste water treatment.

Reactive power compensation during the convergence of grid system with FACTS devices

From the last few years power demanding is increasing as per load requirement. The condition of power demand is not accompanied by only generation and transmission of electricity. Many industrial power plants are running on higher capacity to fulfill load requirement. There are many issues such as voltage instability and power quality which led to many power plants. In distributed generation generators are distributed asynchronous type and mostly affected by the reactive power. They basically cannot generate reactive power but draws away from the power system. It causes the voltage drop to the consumer side which may be not acceptable. Then reactive power management is essential for reducing those problems and provides continuity of electricity to the consumers. Distributed generation systems and FACTS devices are converting conventional power grid into smart grid. Reactive power compensation is now challenging issue to preserve adequate power quality and improve the performance of distribution system. There are many FACTS devices such as we can control power factor of the circuit and reactive power compensation. Many researchers have focused on behavior of FACTS device in an unbalanced condition and majority work is done only with DSTATCOM. This paper deals with different FACTS devices in grid systems with analysis and overview of D-FACTS devices. Hence in this paper, applications of various D-FACTS devices have been described to find location of compensation devices for reliable operation.

Unraveling the association between oral impacts on daily performances and dental caries among adults in a South Indian Metropolis

Objectives: Conventionally, oral health outcomes have been assessed using clinical criteria and the subjective opinions of clinicians. However, these methods have failed to capture the true impact of oral diseases on an individual’s overall quality of life (QoL). Specifically, dental caries and tooth loss have been identified as factors that can significantly affect an individual’s oral health-related QoL (OHRQoL). Taking this into consideration, a recent study was conducted to investigate the association between oral impacts on daily performance (OIDP) scores and the oral health status of adults aged 25 years and older residing in Bengaluru South. Materials and Methods: A cross-sectional study was conducted among 800 adults aged 25 years and older in Bengaluru, South city. Clinical examination was performed using the decayed, missing-filled teeth (DMFT) index. OHRQoL was assessed using the OIDP questionnaire. For statistical analysis, the Chi-square test, Mann– Whitney U-test, Kruskal–Wallis test, and Spearman’s correlation were applied. Results: 70.4% of the study participants had at least one oral impact affecting their daily performances. Out of eight daily performances, the most affected performance was eating, followed by emotional stability and carrying out major work. DMFT was significantly associated with OIDP. Conclusion: The prevalence of OIDPs in this population is high. Oral impacts had affected their QoL primarily through difficulties in eating. Appropriate program implementation is required for the upliftment of such deprived populations.

Lamb and Lion, Eyes and Horns: Spirit Christology in the Apocalypse of John

Abstract What contribution may the Apocalypse of John make to Spirit Christology? This article focuses on Rev 5:5–6, progressively unveiling these verses’ promise for the project of Spirit Christology through the examination of seven theses. The aim of this exercise is mutual enrichment: Spirit Christology gains an expanded biblical basis beyond its traditional concentration on the New Testament gospels, while the theological interpretation of the Apocalypse of John benefits from a Spirit-christological reading heretofore lacking in major works on the theological interpretation of Revelation.

The Concept of the Absurd: Camus' Literary Exploration of Existential Philosophy

This article explores Albert Camus' literary embodiment of the concept of the absurd within the framework of existential philosophy. By analyzing major works such as "The Stranger," "The Plague," and "The Fall," the article illustrates how Camus articulates the conflict between the human quest for meaning and an indifferent universe. The discussion includes an introduction to existentialism, the definition of the absurd, and the thematic and symbolic elements in Camus' novels. The article also addresses Camus' influence on literature and philosophy, his philosophical contributions, and critiques and interpretations of his work. Ultimately, it highlights the enduring relevance of Camus' exploration of the absurd in contemporary discourse, encouraging readers to engage with his works and the profound questions they pose about meaning, existence, and the human condition.

Public Preferences for Surgeon Gender in Saudi Arabia: A Cross-Sectional Analysis.

Gender equity in healthcare ensures equal access to services and resources for all individuals, regardless of gender. Studies show that patients' gender influences their healthcare experiences and decisions, and societal gender preferences impact surgeon selection. Therefore, the objective of this study was to address the surgeons' gender preferences among Saudi Arabia's population. This study used a cross-sectional research design and survey methodology to gather data from a representative sample of adults aged 18 and older from the general population in Saudi Arabia. This study used SPSS version 26 for statistical data entry and analysis, employing descriptive and inferential statistics, frequency distributions, descriptive statistics, and multivariate analysis using multiple logistic regression for variables significantly associated with population gender in univariate analysis. This study involved 2085 participants, with 51.2% aged 18-25, 18.4% aged 26-35, 16.7% aged 36-45, and 13.8% aged 45 and above. The majority were Saudi Arabian, with a majority holding a university degree. The majority worked in the healthcare sector, while the remaining 29.7% were unemployed. This study found that there were significant gender preferences among survey respondents for different types of surgical procedures. Male participants preferred male surgeons for routine non-emergency visits and sensitive obstetric, genital, sexual, and minor procedures (p < 0.001). Female participants, on the other hand, had no preference for emergency surgeries and major surgical procedures (p < 0.001). This study found that participants were more likely to prefer female surgeons for regular non-emergency visits to the surgery clinic (p < 0.001; aOR = 2.344). Additionally, participants had a high preference for female surgeons for sensitive cases (p < 0.001; aOR = 7.064) and minor surgical procedures (p < 0.001; aOR = 2.489). This study underscores the significance of cognizance and the incorporation of a patient's gender preferences when selecting surgical procedures, thus fostering an environment that is more accommodating and focused on the patient.

CURRENT STATE AND DEVELOPMENT PROSPECTS FOR THE RENEWAL OF SEWERAGE NETWORKS IN KHARKIV CITY

Ensuring the reliable operation of sewerage systems is one of the essential tasks of municipal services in Ukrainian cities. As the research shows, in most cases, their construction involved concrete and reinforced concrete, which are prone to destruction under the influence of many factors, particularly microbiological corrosion. The destruction of sewage collectors is often the reason for wastewater leaking into groundwater and soil, resulting in pollution. The article provides statistical data on the ‘Kharkivvodovidvedennia’ Complex of the ME ‘Kharkivvodokanal’ as of 01.01.2024, which operates the city’s external water drainage networks. The article outlines the most common factors that lead to emergencies in sewage networks, such as aging and wear of infrastructure, insufficient maintenance and repair, mechanical damage, pollution and clogging, increased volume of wastewater, planning problems, chemical reactions, biological corrosion, and connection defects. The relationship between these causes may be that corrosion can weaken pipeline materials, making them more vulnerable to mechanical damage and leakage. According to preliminary calculations, it is necessary to relay or rehabilitate (trenchless pipeline laying) at least 22–25 km of city networks annually to ensure the reliability of sewage networks. The article analyses the work cycles performed on the tunnel collectors’ objects and large-diameter collectors over five years. Major repair and reconstruction work that deserves attention includes work on the repair of mine No. 12 of the tunnel collector of the 761 micro-district (mine depth H = 6.75 m, diameter – 5 m); restoration work of the Oleksiivskyi collector Ø 2000 mm near the viewing chamber No. 33 on the street Lopanska; restoration of the collector of the Northern group of factories Ø 900 mm at Danylivskyi Uzviz. As a result, we carried out an analysis of the current state of the sewage network of the city of Kharkiv. The main factor in the wear and tear of sewerage networks is corrosion, which, in turn, can weaken pipeline materials, making them more vulnerable to mechanical damage and leaks. Despite the difficult economic conditions, work on the repair and operation of networks is carried out. Also worthy of special attention for future research is the survey of mines where restoration work took place over the past ten years using modern methods. Keywords: underground construction, sewerage, renewal, repair, reconstruction, bearing capacity, wear, corrosion.

Luther in Norwegian

Abstract: The article traces the translation history of Luther's texts into Norwegian. Until their independence in 1814, the Norwegians became acquainted with Luther through Danish translations. His Small Catechism dominated the reception, mainly due to the Pietist school reform of the 1730s. Hymns and sermons from the Church Postil were important genres in the nineteenth century, but also major works such as Luther's Genesis Lectures and his Galatian commentary appeared in Norwegian. Many of these were translated by conservative theologians, who wanted to preserve Lutheran roots. In the twentieth century, the picture is less clear, but Luther was used in the ongoing battle over the legacy of liberal theology before World War II. The most important publication came as a six-volume edition at the Reformer's 500th birthday, a selection of mostly early writings of Luther, albeit with some texts from his later years.

Filsafat Sosio-politik Al-Farabi dan Implementasinya terhadap Demokrasi

From Greece to the contemporary era, democracy has become the main pillar of the global political system with its basic principle that power comes from the people, making democracy an ideal paradigm. As is well known, there is an impression that democracy has regressed. There are even claims that democracy is an illusion. This article aims to explain how Al-Farabi's socio-political philosophy can be integrated and applied concretely in the dynamics of democracy. The research approach uses qualitative theoretical analysis by referring to Al-Farabi's major works, especially "Al-Madina Al-Fadila." A review was conducted on contemporary journals and relevant literature. Research Findings This study identifies Al-Farabi's philosophical concepts, such as justice, moral leadership, and citizen participation, which have significant potential to shape social and political dynamics. The results provide an overview of the ethical values championed by Al-Farabi and are in line with the basic principles of democracy. The theoretical and practical implications of this research provide a strong impetus for critical reflection and constructive discussion regarding the implementation of democracy in the contemporary context.

Isbijab – a new centre for the development of Islamic law (XI-XII)

The relevance of this article covers historical, religious, local and diplomatic factors, which reflect the importance of research and the multifaceted nature of Isbijab. The purpose is to study the Isbijab School of fiqh law in the Middle Ages in the context of Islamic law and the history of Kazakhstan. In this work, standard historiographical methods are used: historical-systemic method, historical-comparative method, method of historical periodization and others. The main result is to clarify the role of the fiqh school of Isbijab in the context of studying the history of Islamic law on the territory of modern Kazakhstan and in the region as a whole. The authors also found that Isbijab was one of the centres of Islamic studies and law not only in Kazakhstan but also in the whole of Central Asia in the XI to XII centuries. It was the time when Isbijab developed its legal concept and school of fiqh, the Hanafi madhhab. This school of Islamic law introduced a new generation of legal scholars and their pupils, whose major works and academic degrees paved their way in the historiography. Their experience helped the researchers to study the manuscript works of medieval Isbijab jurists from a historical-legal and theological point of view. The paper shows the findings of an ongoing study of Isbijab legal practitioners in the framework of the "Mukhtasar al-Tahawi" book. Work has practical relevance not only in the context of Islamic studies and Islamic law but also in history, international relations, country knowledge and in other disciplines.

Vaccination against COVID-19 among healthcare workers as a cocoon strategy for people living with HIV

IntroductionHealthcare professionals working in infectious disease units are often engaged in the care of patients with HIV infection. A cocoon vaccination strategy may protect those who are immunocompromised from a severe course of COVID-19. MethodsThe research was conducted between January 2021 and June 2022. The study participants were 450 healthcare workers (HCWs) from the Hospital for Infectious Diseases in Warsaw who were vaccinated against COVID-19 with the BNT162b2 mRNA vaccine (Pfizer-BioNTech) –, thefirst available type of vaccine in Poland. Sera were collected according to the schedule of the study. Statistical analyses were performed with non-parametric tests: Wilcoxon's test was used to compare dependent numerical variables, and Fisher's exact test and the Chi-squared test to compare categorical variables. A p value of <0.05 was considered statistically significant. ResultsAmong the 450 HCWs working in the Hospital for Infectious Diseases in Warsaw 412 (91,5 %) were vaccinated against COVID-19. In total 170 (41,3 %) vaccinated HCWs were included in the final analysis. Their median age was 51 years [interquartile range (IQR): 41–60 years] and median body mass index (BMI) was 25.10 [IQR: 22.68–29.03]. Most of the cohort consisted of women (n = 137, 80.59 %), with the majority working directly with patients (n = 137, 73.21 %). It was found that as early as 14 days after the second dose of the vaccine, 100 % of the study participants achieved a positive result for SARS CoV-2 S-RBD antibodies. There were 168 subjects who had had a COVID-19 diagnosis before entering study and after vaccination 65 HCWs was diagnosed with COVID-19. ConclusionsDue to the fact that people living with HIV with severe immunodeficiency may have an incomplete immune response to COVID vaccination and be at risk of a severe course of the disease, the cocoon strategy of vaccinating medical personnel may be beneficial for these patients.