Major Mode Research Articles

A Comparison of Music Characteristics of Funeral Music from Croatia, the Netherlands, and the United Kingdom

Music forms an integral and essential part of funeral rituals worldwide, but has to date received little systematic research attention. Recent investigations into funeral music used in the Netherlands showed that it is lower in tempo and valence, less energetic, and more acoustic than popular music. Funeral music is also often in a major mode. The present study sought to replicate these findings for a Dutch (NL) funeral music sample and to expand upon previous knowledge by investigating the audio features provided by Spotify, namely: valence, energy, tempo, acousticness, instrumentalness, mode, and danceability for funeral music samples from Croatia (HR) and the United Kingdom (UK). First, values of music characteristics for funeral music used in HR, N = 388 pieces, NL, N = 500 pieces, and UK, N = 439 pieces, were compared to values of popular control music from each country separately. Previous findings were replicated: for HR, NL, and UK, funeral music displayed a similar pattern as described above. Second, the values of Spotify audio features for funeral music were compared between countries. Analyses revealed significant differences between NL/UK and HR, namely lower valence and energy and higher acousticness (only HR-UK) and instrumentalness for NL/UK compared to HR. Effect sizes were, however, small and are likely due to differences in music selections. These results suggest that, even though there is much diversity in music pieces and songs, funeral music within and across these European countries is more alike than different in terms of its audio characteristics.

Abstract 3444: Role of AKR1C3 in converting reservoirs of DHEA-S into potent androgens that drive prostate cancer cell growth

Abstract Castration resistant prostate cancer (CRPC) treatment aims to stop a resurgence of androgen receptor (AR) signaling with a class of therapeutics known as androgen receptor signaling inhibitors (ARSI). Through inhibition of CYP17A1, Abiraterone (Abi) prevents an upstream step in androgen biosynthesis, while Enzalutamide (ENZ) acts as an AR antagonist. Despite the early success of ARSI, a subset of patients develop resistance and succumb to the disease. One major mode of resistance is thought to occur when steroidogenic enzymes that are upregulated in CRPC convert weaker circulating precursors to testosterone (T) and dihydrotestosterone (DHT) to restore AR signaling. In this study, we identify a mechanism driving intratumoral steroidogenesis that involves AKR1C3 (type 5 17β-hydroxysteroid dehydrogenase type 5). AKR1C3 is a major steroidogenic enzyme in the prostate that is involved in all androgen biosynthetic pathways to T and DHT, upregulated in CRPC patients, and is a component of Abi and ENZ drug resistance. Previously with Taplin et al. we observed in patients on Leuprolide that T was reduced to 5 ng/dL, and the addition of Abi lowered DHEA-S by 90% (from 230,000 ng/dL to 22,000 ng/dL). However, the DHEA-S that remained was 4,000x greater than circulating T, making it a reservoir for intratumoral steroidogenesis post Abi treatment. Here, we demonstrate that post-Abi concentrations of DHEA-S, and castrate levels of DHEA-S (post-leuprolide but pre-Abi treatment), which also corresponds to DHEA-S levels patients on ENZ are 1) converted to T in an AKR1C3-dependent manner in prostate cancer (PCa) cells, and 2) sufficient to stimulate AKR1C3-dependent cell growth. Our observations are consistent across both primary and metastatic PCa cell lines, CWR22PC and DuCaP, respectively. Androgen measurements were made using our highly sensitive and specific stable isotope dilution liquid chromatography tandem mass spectrometry (SID-LC-MS/MS) method. Additionally, we demonstrate AKR1C3-dependence using genetic and pharmacological approaches with an AKR1C3 stable knockdown for each cell line and two AKR1C3 competitive inhibitors. Taken together, we have identified a mechanism of resistance to ARSIs common to both primary and metastatic cell lines that operates through AKR1C3’s intratumoral conversion of DHEA-S to potent androgens that drive prostate cancer growth. Citation Format: Andrea J. Detlefsen, Ling Duan, Clementina Mesaros, Trevor M. Penning. Role of AKR1C3 in converting reservoirs of DHEA-S into potent androgens that drive prostate cancer cell growth [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 3444.

The role of intralaminar damages on the delamination evolution in laminated composite structures

Delamination is a major failure mode affecting laminated composite structures. This failure mechanism, if not properly monitored, can lead to uncontrolled cracks growth and premature structural collapse. Thus, predicting delamination propagation is mandatory to determine the structural integrity. At present, delamination has been extensively investigated in laminated composite structures but only a few studies have been performed on how the intralaminar damages influence the interfacial release energy and, consequently, the delamination evolution. In this paper, the well-established SMart-Time XB delamination simulation tool, has been coupled with a Hashin Criteria based User-Material Subroutine (UserMat) to study the role of the intralaminar damages in delamination propagation. A benchmark case based on the mixed-mode I/II Single Leg Bending (SLB) specimen for delamination evolution assessment under quasi-static loading has been investigated. Subsequently, a composite material plate, characterized by an artificial circular delamination, under compression has been considered. This study proved to be valuable by underlining the influence of fibre and matrix breakage on the interlaminar damages evolution. Interestingly, taking into account the effect of intralaminar flaws changes the local energy release rates values on the delamination front and, consequently, the crack shape and evolution.

Dynamics and Characteristics of Compound Heatwaves over Asia

The increasing frequency of heat waves in East Asia (EA) affects agriculture, water management, and people's livelihoods. In recent years, record-breaking heatwaves have occurred corresponding to extreme drought and are increasing in frequency. The two leading modes of heatwavesoverEA are closely related to dry conditions, but their temporal developments are somewhat different. The first major mode of heatwaves appears over northern EA, starting in early summer and lasting throughout the summer. The second mode of heatwaves occurs over central China and Korea and is closely related to negative precipitation anomalies during late summer and startsin July or August.This study investigated the quantitative feedback attribution of heatwave-related surface temperature anomalies using the coupled air-surface climate feedback-response analysis (CFRAM). The warming anomalies related tothe first mode of heatwaves are usually controlled by cloud, latent heat, and surface dynamics processes. It can be explained by reducing heat release from the surface to the atmosphere due to the lack of soil moisture under severe dry conditions.While surface warming related to the second mode of heatwaves is contributed by cloud feedback and atmospheric dynamic process. Reduction in cloud area associated with anticycloniccirculation anomalies induces increased insolation and it affects surface warming. However, the effect of humidity on high-temperature events has not yet been fully explored. Thus, this study identifiedcompound heatwaves that are described simultaneously with relative humidity conditions and suggested the future projections of two types of heatwaves over EA using phase six of the Coupled Model Intercomparison Project (CMIP6) model simulation. CMIP6 models projected intensification of dry heatwaves and increased moist heatwave days in response to projected increases in greenhouse gas concentrations.

The effect of rural roads on consumption in Ethiopia

PurposeThis study empirically examines the impact of rural roads on consumption of households in Ethiopia.Design/methodology/approachBoth descriptive statistics and econometric techniques are used to address the aforementioned objective. Specifically, quantile regression, fixed- and random-effect models are used to understand the impact of rural road quality on welfare.FindingsThe econometric analysis revealed that improving the quality of rural roads and/or creating access to all-weather roads raises households' average real consumption per capita by as much as 10%. The other transport indicator – mode of transport – also has a positive effect on real consumption per capita. The result indicated that real consumption per capita for households using the traditional mode of transport would increase by as much as 7% compared to those using foot as a major mode of transport. However, the fixed quantile estimation result revealed that rural road access has a positive and significant effect on consumption per capita only for the 0.8th and 0.9th percentiles, indicating that the access to roads is not pro-poor.Research limitations/implicationsImproving rural roads to a level of all-weather road standards and provision of agricultural transport facilities should be strategic priorities.Originality/valueThis study provides empirical evidence pertinent to the effect rural mobility has on the consumption of households as well as the pro-poorness of such investments in rural settings.

Improved collection of rooftop micrometeorites through optimized extraction methods: The Budel collection

AbstractThe scientific value of micrometeorites collected from deep‐sea sediments or glacial deposits can be limited by poorly constrained accumulation times or severe alteration, coupled with a complex infrastructure of sampling expeditions. Collecting micrometeorites from rooftops has recently become a feasible alternative, but extraction methods have not been optimized or standardized to date. Here, we show that existing methods for the recovery of melted cosmic spherules (CSs) can be strongly improved by using a sequence of mineral separation techniques, including shape separation with an asymmetric vibrator and heavy liquid density separation with overflow centrifuges. We retrieved 1006 micrometeorites from the gutter of a barn in Budel, the Netherlands. Particle diameters are 80–515 μm, with the major mode at 130 μm and a slope exponent of −4.88. Differences in size distributions among various types of CSs indicate a multi‐source influx, with CS textures controlled by their parent body's mineralogy and orbital parameters. Repeated sampling of the rooftop after accumulation times of 959 and 333 days allows for a time‐integrated global mass flux estimate of 472 t year−1. This estimate is notably higher than previous rooftop‐based estimates but is still severely affected by micrometeorite loss from the gutter through drainage. The mass flux peaks at an equivalent particle diameter of ~200 μm. The Budel collection is the first rooftop collection to contain abundant vitreous micrometeorites and include the coarse‐grained S‐type CS class. Unmelted and I‐type micrometeorites remain difficult to extract from rooftop samples. Vitreous micrometeorites display various stages of weathering, showing that severe alteration of glass can progress at a faster rate in populated regions than previously assumed. This study demonstrates that methodological adjustments can drastically increase the scientific potential of rooftop micrometeorite collections.

Design and Implementation of a Futuristic EV Energy Trading System (FEETS) Connected with Buildings, PV, and ESS for a Carbon-Neutral Society

To realize carbon neutrality, understanding the energy consumed in the building sector, which is more than that in other sectors, such as industry, agriculture, and commerce, is pivotal. Approximately 37% of energy consumption belongs to the building sector, and management of building energy is a critical factor. In this paper, we present an energy sharing scenario for energy stabilization, assuming that electric vehicles and their charging stations are widely distributed in the future. Consequently, fewer fuel cars will exist, and electric cars will become the major mode of transportation. Therefore, it is essential to install charging stations for electric vehicles in the parking lots of future buildings, and business models are expected to expand. In this paper, we introduce a future energy stabilization mechanism for peak power management in buildings and present a platform that entails connection-based energy trading technology based on a scenario. We also propose an energy supply strategy to prevent excess prices incurred due to peak consumption. Then, we analyzed the electricity bill for one month through scenario-based simulations of an existing building and the proposed system. When applying the proposed system, we derived a result that can reduce electricity rates by 38.3% (best case) to 78.5% (worst case) compared with the existing rates.

Single crystal structure of nitro terminated Azo Schiff base: DNA binding, antioxidant, enzyme inhibitory and photo-isomerization investigation

Novel azo schiff base compound, namely, 2‑hydroxy-5-[(E)-phenyldiazenyl] benzaldehyde (AzNP) was synthesized by reacting 2‑hydroxy-5-[(E)-phenyldiazenyl]benzaldehyde and 4-(4-nitrophenoxy)benzenamine under inert conditions. The synthesized compound AzNP was characterized by Fourier transform (FT-IR), Nuclear magnetic resonance (NMR) and Ultraviolet-visible (UV–vis) spectroscopy. The solid state structure was elucidated by single-crystal X-ray crystallography. The compound was crystallized in the Monoclinic system with P 1 21/c1 space group, having a = 6.4859(3 Å, b = 15.6673(7) Å, c = 19.7908(9) Å, β = 90.945(2), and Z = 4, showing only one intermolecular C21-H21...N2 interaction, with donor and acceptor distance of 3.5774(16) Å, responsible for the elegant 3D network of the structure. DFT calculations were performed for structure-property relationship information of AzNP. In order to comprehend the selectivity behavior of the compound, binding interaction with CT-DNA was examined using standard optical spectroscopy. The observed hypochromism in the binding studies indicated that ligand substantially interact via the groove binding mode (Kb =9.91×103 mol−1dm3) with the DNA. Further assessment of binding mode of AzNP with DNA was made through hydrodynamic measurement and molecular docking analysis which confirmed the major groove binding mode of the ligand. Additionally, the DPPH (2,2-diphenyl-1-picrylhydrazyl), the ferric reducing power, and the α-amylase inhibition assays were used to evaluate the biological significance. Analysis of Cis-Trans conformational changes was also done to investigate photoisomerization properties of synthesized compound AzNP.

Thermal performance of the aquifer thermal energy storage system considering vertical heat losses through aquitards

The aquifer thermal energy storage (ATES) system is an efficient method to overcome the gap between energy supply and demand over time and space. Heat storage and preservation abilities are key issues of a successful ATES project. However, most of previous studies only focus on heat storage and recovery abilities of the ATES, while the heat preservation ability of aquitards is neglected. Besides, effects of key factors on heat losses into aquitards still remain unclear, which makes appropriately selecting reservoirs for the heat storage challenging. Thus, the heat loss efficiency is defined to represent the heat preservation ability of aquitards, through which ATES thermal performances are comprehensively evaluated. Effects of key factors on thermal performances are analyzed and optimal reservoirs for the heat storage are recommended. Results indicated that key factors had different impacts on heat losses and thermal recovery. The conduction was the major loss mode and was sensitively affected by aquitard parameters. An aquifer with a lower thermal conductivity, a higher porosity and a superior heat capacity was more suitable for the heat storage. The aquitard with lower porosity, thermal conductivity and heat capacity was better. On the premise of sealing, increasing the aquitard permeability was conducive.

Ethnobotanical survey and utilization of medicinal and food plants of Panjgur Balochistan, Pakistan

Abstract. Ayoub M, Saeed S, Ahmed A, Ahmed M. 2023. Ethnobotanical survey and utilization of medicinal and food plants of Panjgur Balochistan, Pakistan. Asian J Ethnobiol 6: 27-36. The present study observes the ethnobotanical and ethnopharmacological of indigenous rural communities' knowledge of the Panjgur District of Balochistan, Pakistan. The rural community of Panjgur utilizes different plants as medicine and food, and wild food plants play a secondary role in dietary supplementation. The study aimed to document medicinal plants and traditional herbal medicines used by rural people in the area. Plant specimens were collected, and plant uses were recorded by semi-structured interviews and group discussions of 120 informants, of which 90 were males and 30 were females under different age groups. A total of 63 species were used as medicine or food by local communities. Most species reported were herbs (56%), followed by shrubs (24%). The major preparation mode was fresh use (36%), and leaves were the main parts used. The total use citations for all the plant species used to cure various ailments were reported. The highest use citation for stomachic problems followed by a throat infection, anti-acne, skin allergy, and joint pain. The Use Value (UV) ranged from 0.03 to 3 by Cannabis sativa, followed by Aloe vera, Arundo donax, Chenopodium album, Citrullus colocynthis, Convolvulus arvensis, Prosopis juliflora, Phoenix dactylifera, Lactuca sativa, Ziziphora clinopodioides, and Cestrum nocturnum. This study is the first initiative for ethnobotanical investigation in the Panjgur District of Balochistan. The local community not only uses these medicinal and food plants as food and for herbal treatments but also considers them a source of income. The information generated from this study will also provide a baseline for future investigation to be carried out to evaluate the nutritional and bioactive properties of wild medicinal and food plants.

Detrital zircon U[sbnd]Pb geochronology of modern river sediment in the Eastern Pamir Syntaxis and its implications for the formation of the Pamir and growth of the Tibetan Plateau

The Eastern Pamir Syntaxis links the western Tibetan Plateau with the western syntaxis of the Himalayan-Tibetan orogen. Quantifying temporal and spatial variations in uplift rates for the Eastern Pamir Syntaxis is critical for understanding the growth of the Himalayan-Tibetan orogen. To better understand these variations, we report n = 285 new detrital zircon UPb ages from sediments in modern rivers of the Eastern Pamir Syntaxis. When compared with previous work, our data, with a major age mode around ∼107 Ma, indicate that siliciclastic sediments in the Taxkorgan River were primarily derived from Cretaceous rocks. Whereas a less prominent age mode around ∼13 Ma suggests that Miocene rocks made an important sediment contribution to the Taxkorgan River. The other notable age modes are in the range of 200–300 Ma and 600–800 Ma. Our data suggest that detrital zircon UPb signatures for rivers draining the Eastern Pamir Syntaxis change significantly from south to north, and the influence of Cretaceous proto-sources gradually diminishes northward. Because Tibetan sutures are traceable into the Pamir, these data help define the distribution of late Early Cretaceous rocks associated with the closure of the Meso-Tethys within the Pamir. These data support the establishment of the modern-like river pattern in the Eastern Pamir Syntaxis contemporaneous with activity on the Kongur Extensional System in the northeast Pamir.

Pulmonary Paragonimiasis: A Case Series.

case reports; eosinophilia; paragonimiasis; pleural effusion.

An AKT1-and TRIM21-mediated phosphodegron controls proteasomal degradation of HuR enabling cell survival under heat shock

Post-transcriptional regulation by RNA-binding proteins (RBPs) is a major mode of controlling gene expression under stress conditions. The RBP HuR regulates the translation/turnover of multiple mRNAs in stress responses. HuR is degraded in response to heat stress consequent to ubiquitination of the K182 amino acid residue. We have identified TRIM21 as the E3-ubiquitin ligase causing HuR polyubiquitination at K182 and proteasomal degradation under heat shock. The S100 and E101 residues are required for binding of TRIM21 to HuR. Heat shock-induced phosphorylation of S100 is necessary for TRIM21 interaction with HuR and subsequent degradation. We identified AKT1 as the kinase which phosphorylates S100, allowing the recognition of HuR by TRIM21. Sequential phosphorylation by AKT1 and ubiquitination by TRIM21 therefore determine a "phosphodegron" in HuR that is required for regulating the cellular level of HuR under heat shock, thereby enabling a crucial adaptive mechanism allowing cell survival in response to heat stress.

A brGDGT‐Based Reconstruction of Terrestrial Temperature From the Maritime Continent Spanning the Last Glacial Maximum

AbstractThe tropics exert enormous influence on global climate. Despite the importance of tropical regions, the terrestrial temperature history in the Indo‐Pacific Warm Pool (IPWP) region during the last deglaciation is poorly constrained. Although numerous sea surface temperature (SST) reconstructions provide estimates of SST warming from the Last Glacial Maximum to the Holocene, the timing of the onset of deglacial warming varies between records and inhibits determining the forcings driving deglacial warming in the IPWP. We present a 60,000‐year long temperature reconstruction based on branched glycerol dialkyl glycerol tetraethers (brGDGTs) in a sediment core from Lake Towuti, located in Sulawesi, Indonesia. BrGDGTs are bacterial membrane‐spanning lipids that, globally, become more methylated with decreasing temperature and more cyclized with decreasing pH. Although changes in temperature are the dominant control on brGDGTs in regional and global calibrations, we find that the cyclization of the brGDGTs is a major mode of variation at Lake Towuti that records important changes in the lacustrine biogeochemical environment. We separate the influence of lake chemistry changes from temperature changes on the brGDGT records, and develop a temperature record spanning the last 60,000 years. The timing of the deglacial warming in our record occurs after the onset of the deglacial increase in CO2 concentrations, which suggests rising greenhouse gas concentrations and the associated radiative forcing may have forced deglacial warming in the IPWP. Peaks in temperature around 55 and 34 ka indicate that Northern Hemisphere summer insolation may also influence land surface temperature in the IPWP region.

A Social Network Analysis of Large-Scale Wildlife Seizures Made at US Ports of Entry

ABSTRACT The United States is among the largest markets of both legal and illegal wildlife in the world. Prior studies of wildlife seized at US ports of entry have demonstrated that a small number of flora and fauna species account for a disproportionate share of illicit wildlife seizures and that a select number of entry ports and export countries account for the large majority of these seizures. However, the distributional flow of wildlife entering the US – the patterns of where a particular wildlife originates and the port of entry it arrives at – remains unclear. Using a social network analysis to model 31,270 large-scale trafficking incidents between 2003 and 2012, we found that removing five ports from the network would disrupt over 66% of the illegal wildlife trade by each major mode of transportation (air cargo, mail, personal baggage, ocean cargo). Further, certain ports have emerged as important seizure hubs regardless of transportation modes, such as San Francisco and Los Angeles, while other US entry ports are highly dense and seized most illicit wildlife specifically by one transportation mode. On the exporter side, China, Mexico, and Southeast Asia had an outsized effect on network clusters and should be targeted for network fragmentation and anti-trafficking education campaigns.

Benefits of having regular practical sessions at medical universities

Practical education is slowly making its way towards becoming the major mode of education especially in medical universities. Not only medical students many other people are also studying through practical education. Practical education these days is mainly based on bookish learning. Even when coming to remote rural areas, many world-class educational institutes are offering practical lessons to students. Practical education helps students understand the relationship between theory and practice. Without theory, there is no real practical education. Practical training imparts students with the basic knowledge on how to handle an emergency condition. On the one hand, it also helps students learn how to treat diseased people. Here in this article, we will discuss about how having daily practical sessions benefits medical students.

Activation of E3 ubiquitin ligase WWP2 by non-receptor tyrosine kinase ACK1.

WW domain containing E3 ubiquitin protein ligase 2 (WWP2) is a member of the NEDD4 E3 ubiquitin ligase family. WWP2 ligase activity is regulated by the 2, 3-linker auto-inhibition. Tyrosine phosphorylation of the 2, 3-linker was identified as an activating means for releasing the auto-inhibition of WWP2. However, the tyrosine kinase (TK) for the phosphorylation and activation remains unknown. In this report, we have found that non-receptor TK ACK1 binds to the WW3 domain of WWP2 and phosphorylates WWP2. ACK1 phosphorylates WWP2 at the 2, 3-linker and partially activates the ubiquitination ligase activity. Unexpectedly, tyrosine phosphorylation of the 2, 3-linker seems not a major mode for activation of WWP2, as ACK1 causes much higher activation of the 2, 3-linker tyrosine phosphorylation defective mutants of WWP2 than that of wild-type WWP2. Furthermore, epidermal growth factor (EGF) stimulates tyrosine phosphorylation of WWP2 and this EGF-stimulated phosphorylation of WWP2 is mediated by ACK1. Finally, knockdown of WWP2 by shWWP2 inhibits the EGF-dependent cell proliferation of lung cancer A549 cells, suggesting that WWP2 may function in the EGFR signaling in lung cancer progression. Taken together, our findings have revealed a novel mechanism underlying activation of WWP2.

Outbreak of Lumpy skin disease in India 2022- an emerging threat to livestock & livelihoods

An ongoing outbreak of Lumpy skin disease (LSD) has affected many states in India since May 2022. The disease originated in Zambia in 1929. The disease first appeared in South Asia in July 2019, with Bangladesh reporting an outbreak. India reported its first ever Lumpy skin disease outbreak in August 2019. LSD is a contagious epizootic disease caused by the Capri pox virus, which spreads among cattle. The major mode of transmission is vector-borne. There is no specific treatment for LSD. The current preventive measure include vaccination, movement control of bovine animals and quarantining, implementing biosecurity through vector control. There is no evidence that it can affect humans. The current outbreak in India has a wide range of morbidity rates, and higher range of mortality rates among cattle, comparing to the previous outbreak. The outbreak has resulted in huge economic implications for dairy farmers, which is exacerbated by the spread of misinformation through social media.

The Perceptual and Emotional Consequences of Articulation in Music

Two experiments investigated perceptual and emotional consequences of note articulation in music by examining the degree to which participants perceived notes to be separated from each other in a musical phrase. Seven-note piano melodies were synthesized with staccato notes (short decay) or legato notes (gradual/sustained decay). Experiment 1 (n = 64) addressed the impact of articulation on perceived melodic cohesion and perceived emotion expressed through melodies. Participants rated melodic cohesion and perceived emotions conveyed by 32 legato and 32 staccato melodies. Legato melodies were rated more cohesive than staccato melodies and perceived as emotionally calmer and sadder than staccato melodies. Staccato melodies were perceived as having greater tension and energy. Experiment 2 (n = 60) addressed whether articulation is associated with humor and fear in music, and whether the impact of articulation depends on major vs. minor mode. For both modes, legato melodies were scarier than staccato melodies, whereas staccato melodies were more amusing and surprising. The effect of articulation on perceived happiness and sadness was dependent on mode: staccato enhanced perceived happiness for minor melodies; legato enhanced perceived sadness for minor melodies. Findings are discussed in relation to theories of music processing, with implications for music composition, performance, and pedagogy.

Happy and sad music acutely modulate different types of attention in older adults.

Of the three subtypes of attention outlined by the attentional subsystems model, alerting (vigilance or arousal needed for task completion) and executive control (the ability to inhibit distracting information while completing a goal) are susceptible to age-related decline, while orienting remains relatively stable. Yet, few studies have investigated strategies that may acutely maintain or promote attention in typically aging older adults. Music listening may be one potential strategy for attentional maintenance as past research shows that listening to happy music characterized by a fast tempo and major mode increases cognitive task performance, likely by increasing cognitive arousal. The present study sought to investigate whether listening to happy music (fast tempo, major mode) impacts alerting, orienting, and executive control attention in 57 middle and older-aged adults (M = 61.09 years, SD = 7.16). Participants completed the Attention Network Test (ANT) before and after listening to music rated as happy or sad (slow tempo, minor mode), or no music (i.e., silence) for 10 min. Our results demonstrate that happy music increased alerting attention, particularly when relevant and irrelevant information conflicted within a trial. Contrary to what was predicted, sad music modulated executive control performance. Overall, our findings indicate that music written in the major mode with a fast tempo (happy) and minor mode with a slow tempo (sad) modulate different aspects of attention in the short-term.