AbstractModern agriculture has posed a great impact upon natural resources in terms of exploitation and their luxurious use. Ever increasing population pressure has exhausted the sustainable agricultural production system by exploiting land and water resources. High external inputs, required for high yield targets, are nowadays heavily dependent upon artificial sources and ways, amongst which nitrogen (N) is of global concern. Nitrogen is required by crops for active growth and photosynthetic machinery throughout the crop cycle. Among cereals, maize has the highest yield potential, hence it removes huge amounts of N and water from soil. To achieve high yields, farmers mostly use high dose of N fertilizers, causing soil, water and environmental pollution in the form of soil degradation, eutrophication and volatilization, thus reducing nitrogen use efficiency (NUE). This review critically focuses on N fertilizer management and regulation in maize farming systems with high population density. Achievements ha...