Since the beginning of 2020, media around the world have started and intensified their TikTok activity to gain notoriety and reach young people, their main user group. However, as with other previously popularized social media, such as Facebook or Twitter, the platform’s logic is different from that traditionally employed by the media system when developing information products. The objective of this paper is to analyze the degree of adaptation to the logic of this network for the activity developed on it by the Spanish media. For this purpose, a combined methodology of quantitative and content analysis was applied to 446 videos posted by the official user accounts of 20 Minutos, Antena 3 Noticias, El Diario, El Mundo, and El País –the five media outlets with the largest online audience in that period –from the time the accounts were created until January 31, 2022. Specifically, we studied the activity developed, the notoriety achieved, and the interaction obtained, as well as the most common formats, topics, protagonists, and brand identity elements. The results show that the main Spanish media have tried to adapt to the entertainment logic of the platform both with the use of native editing resources as well as through the creation of original materials, predominantly soft news, about entertainment, celebrities, and lifestyle. The videos that gain more notoriety are those that are more adapted to this logic. However, the Spanish media analyzed post less frequently than international media, obtain fewer views, and register lower engagement levels; in addition, they do not use their presence on this social network to promote their other editorial products.