Purpose: The European registry for minimally invasive pancreatic surgery (E-MIPS) collects data on laparoscopic and robotic MIPS procedures in all low- and high-volume centers across Europe. The aim is to monitor and report on safety and quality outcomes of MIPS in daily clinical practice. Pancreatic surgery is known for high postoperative morbidity rates. The minority of these procedures is done through a minimally invasive approach. Methods: This is an analysis in the prospective multicenter E-MIPS registry, including data of all minimally invasive distal pancreatectomies (MIDP) and minimally invasive pancreatoduodenectomies (MIPD) of the first year (2019) of the E-MIPS registry. Main study parameters were patient demographics, perioperative- and oncological outcomes. Subsequently, a comparison between the laparoscopic and robotic approach was made. All analyses were performed on an intention-to-treat basis. Results: A total of 1122 patients from 55 centers in 15 countries were included, 559 patients underwent MIDP, 401 patients MIPD and 163 other MIPS procedures. Overall 90 day mortality was 6 (1.1%) for MIDP and 15 (3.7%) for MIPD. MIDP was mostly performed laparoscopic (401 laparoscopic [79.6%], 157 robot) and MIPD mostly robotic (167 laparoscopic, 234 robot [55.6%]). Median annual hospital volume for MIDP was 10 (IQR 7-20) and 9 for MIPD (IQR 2-20). In 30/55 centers, MIPD was conducted of which 13/30 (43%) centers performed ≥20 MIPD annually. Conclusions: This first report of the E-MIPS quality registry shows that MIDP is mainly performed using laparoscopy whereas MIPD is mostly performed using the robot. Higher center volumes for MIPD are reported in Europe than in previous studies from the United States. The E-MIPS registry will continue to monitor the practice and outcomes of MIPS in Europe.